Ascorutin tablets: instructions for use, price, reviews during pregnancy. Indications for use

pharmachologic effect

Ascorutin - what is it?

This pharmaceutical drug is a combination drug that has the properties of a vitamin and other useful biological components included in the tablets. By inhibiting the activity of the enzyme hyaluronidase , rutin and ascorbic acid reduce the permeability and fragility of capillaries, which significantly strengthens the vascular wall of the microcirculatory and macrocirculatory beds. The combination of active components makes it possible to inhibit the aggression of platelets , the main cellular element of the blood clotting system, due to which the drug suppresses nosological units, which are based on increased thrombus formation.

Vitamin C also has antioxidant properties, that is, it protects cellular structures from the harmful effects of oxidized molecules, free radicals and peroxidation of the bilipid membrane. These therapeutic effects are used in the fight against acute respiratory diseases . In addition, ascorbic acid takes part in many redox metabolic pathways. For example, the participation of this biologically active component in the metabolism of fats, the synthesis of collagen and other connective tissue proteins, the reactions of conversion of folic acid into folinic acid, the synthesis of catecholamines, the metabolism of aromatic acids and the metabolism of steroid hormones, in particular, in the metabolism of thyroxine .

It should not be forgotten that ascorbic acid is a powerful factor in the body's defense, both as part of the immune system and as a nonspecific agent. By enhancing the processes of natural repair and restoration of cellular elements, vitamin C increases resistance to infections and reduces exposure to various types of exogenous allergens.

Rutin exhibits strong anti-inflammatory effects, which are actively used in the conservative treatment of certain diseases. The mechanism of action is to reduce the exudation of the liquid part of the plasma and diapedesis of cellular elements into the pathological focus through the vascular wall. That is, one of the extremely important stages in the development of a typical inflammatory process is eliminated. We should not forget that rutin also has choleretic and mild antihypertensive effects, which helps normalize the functions of the cardiovascular and digestive systems.

Ascorutin tablets - what are they for?

Due to the breadth of the pharmacological action of the drug, it is very difficult to say exactly what these tablets are for. Of course, like any medicine, there is a certain list of indications for conservative therapy with Ascorutin, however, popular advice also recommends using the drug to reduce swelling and pain in chronic venous insufficiency . Rutin in combination with vitamin C eliminates trophic disorders, especially in the lower extremities, as it cleanses and strengthens the vascular bed.

It has been clinically confirmed that Ascorutin can be used in oncology. What is it used for? Medical research has proven that cancer cells are a kind of “trap” for beneficial nutrients, including vitamin complexes. Therefore, in order to avoid the development of hypovitamin pathological conditions, tablets are also prescribed to cancer patients.

What childhood diseases are treated with ascorutin?

Ascorutin is very effective in fighting infections. The poor condition of the vascular system greatly aggravates the course of diseases such as influenza, scarlet fever, tonsillitis and measles. The drug serves to strengthen the walls of blood vessels, eliminates their fragility, and improves permeability. It relieves skin rashes that often accompany infectious diseases.

With the help of ascorutin, it is possible to prevent and alleviate the course of childhood chronic glomerulonephritis. These diseases are expressed in the impact of infection on the kidneys, further tissue inflammation, swelling and loss of organ functionality. Glomerulonephritis is accompanied by accelerated loss of proteins, which entails weakening of the child’s body. Ascorutin takes an active part in returning the renal tubules and glomeruli to their functionality. During the treatment of glomerulonephritis in children over 3 years of age, the drug is often included in a complex of health procedures.

Ascorutin helps to effectively treat children suffering from hemorrhagic diathesis

Increased bleeding can be caused by capillary toxicosis (Henoch-Schönlein disease). Children aged 5–10 years are often susceptible to this disease. The pathology develops in the process of joining an allergic reaction to the vascular tissues to the infection. Due to excessive capillary permeability, the skin becomes covered with a characteristic rash. Hemorrhagic diathesis is also expressed by thrombocytopenic purpura (Werlhof's disease), in which blood clotting is impaired as a result of platelet deficiency. Ascorutin, which is involved in the complex treatment of hemorrhagic diathesis, strengthens blood vessels and reduces the activity of the enzyme hyaluronidase, which destroys intercellular tissue.

Ascorutin is used to treat nosebleeds in children.

Indications for use of Ascorutin

Indications for use of the drug Ascorutin are as follows:

prevention of hypo- and avitaminosis P and C;
treatment of deficiency of vitamin complexes;
impaired vascular permeability (for example, hemorrhagic diathesis , radiation sickness , retinal hemorrhages, septic endocarditis , glomerulonephritis , capillary toxicosis , arachnoiditis , allergic diseases, thrombocytopenic purpura , typhus , measles and scarlet fever as part of complex therapy);
preventive treatment of colds;
elimination of flu ;
capillary lesions that are associated with the direct effect of other drugs (indirect anticoagulants or salicylates, for example).

Pharmacological effect

What are the benefits of Ascorutin? A combined vitamin-containing product helps solve many problems with various diseases. Ascorutin is prescribed to enhance redox processes, to establish carbohydrate metabolism, and the synthesis of natural steroid hormones. The drug also takes an active part in the restoration and synthesis of connective tissue in the body.

In addition, the medicine weakens the effects of radiation, promotes the elimination of waste and toxins, which is important during the recovery period from influenza, acute respiratory viral infections and other diseases. Indications for the use of the drug Ascorutin include conditions in patients with acute venous insufficiency, accompanied by pain, swelling, and vascular inflammation

Contraindications

Contraindications for use include the following pathological conditions and nosological entities:

increased individual sensitivity to the constituent components of the drug;
hereditary or acquired intolerance to auxiliary or biologically active substances;
increased blood clotting;
thrombophlebitis with a tendency to thrombosis ;
diabetes;
severe kidney disease;
gout , oxalaturia , urolithiasis , hypokalemia , cystinuria ;
malabsorption syndrome or maldigestion syndrome ;
fructose intolerance;
first trimester of pregnancy ;
children under 4 years of age.

Contraindications and side effects

Despite the fact that Ascorutin is a regular vitamin, the drug has contraindications. First of all, this is individual sensitivity to the components that make up it.

The drug is prescribed with caution in cases of increased blood viscosity and a tendency to form blood clots.

Ascorutin is not recommended for people with chronic diseases of the urinary system, including urolithiasis and renal failure. The drug is prohibited for patients with impaired potassium-magnesium homeostasis. Diabetics should be careful when choosing a product, giving preference to drugs without sugar.

Taking the drug may be accompanied by symptoms such as:

nausea;
dizziness;
allergic reactions;
loose stools;
vomit.

If the side effects are pronounced, it is better to stop taking the drug.

Overdose

Exceeding the therapeutic dose of ascorbic acid can cause an increase in the concentration of oxalic acid in the urine, crystallization of citrates and urates. The consequence is diarrhea or urolithiasis.

Side effects

Adverse effects of conservative treatment and various side effects are extremely rare, because the main active components of a pharmaceutical drug are part of the natural metabolism of the human body, but the following manifestations may occur:

From the central nervous system: headache , disturbance of sleep and wakefulness, increased fatigue, increased excitability of the central nervous system.
From the blood system: thrombocytosis, hyperthrombinemia , increased production of red blood cells and platelets, neutrophilic leukocytosis .
Cardiovascular system: disruption of natural tissue trophism, cardiac muscle dystrophy , increased blood pressure (hypertensive crises), development of microangiopathies.
On the metabolic side: inhibition of the normal function of the pancreatic insular apparatus (manifested in the form of hyperglycemia , glucosuria ) and glycogen synthesis, fluid and sodium retention by the body, hypervitaminosis C , impaired metabolic properties of zinc and copper.
Gastrointestinal tract: irritation of the mucous membrane of the digestive tube, heartburn , nausea, vomiting, diarrhea .
Allergic reactions (occur extremely rarely): skin rashes, itching , angioedema , anaphylactic shock , urticaria .

Ascorutin tablets, instructions for use (Method and dosage)

The pharmaceutical drug is prescribed for use orally, since the active ingredients are well absorbed from the gastrointestinal tract. The dosage of the drug, as a rule, is selected individually, based on the needs, stage of the pathophysiological process of the nosological unit, age and other physical parameters. Also, the amount of the drug used is influenced by the initial data of clinical tests. However, there are general schemes for prescribing Ascorutin for children, adolescents and adults.

How to take Ascorutin for adults

For preventive purposes, 1-2 tablets are used once a day, and for treatment, 1-2 tablets are prescribed 2-3 times a day. The dosage regimen may vary depending on the nosological unit at the discretion of a qualified specialist who prescribes the drug for conservative therapy.

A repeated course of treatment is carried out upon request and is also regulated by the attending physician.

Instructions for use of Ascorutin for children

For the age category over 4 years, a dosage of half or a whole tablet is used as an active prevention of various pathologies (for which Ascorutin is used in preventive sanitation, see above).

For therapeutic purposes, children under adolescence are prescribed half or a whole tablet 2-3 times a day. The average duration of the course is 3-4 weeks; as a rule, the exact duration is prescribed by the attending physician.

Adolescents are prescribed adult dosages with mandatory preliminary monitoring of all systems and organs, since the irreversible consequences of conservative treatment in this age category are manifested by the most severe symptoms.

Rules of use for pregnant women

The drug should not be used in the first trimester due to the risk of developing a pathological condition of vitamin C oversaturation. It is also strictly forbidden to use Ascorutin in combination with other mineral-vitamin complexes. For women in the critical period, 1 tablet is prescribed 2-3 times a day. It is not recommended to drink the pharmaceutical drug with mineral or alkaline water, otherwise the ability of the active ingredients to be absorbed in the digestive tube will significantly deteriorate.

Composition and properties

According to the instructions for use, “Ascorutin” is produced in the form of tablets for oral administration. The tablets are yellowish-green in color with small inclusions. One package can contain 30 or 50 tablets. The drug contains the following active ingredients:

Vitamin C.
Rutin (vitamin P).

Auxiliary components of the drug are calcium stearate, talc, potato starch, sugar.

The combination of two vitamins makes the scope of Ascorutin quite wide. It is often prescribed as part of complex therapy for the treatment of various pathologies. The goal of such therapy is to increase the intensity of redox processes, improve carbohydrate metabolism, and stimulate the production of natural steroid hormones. In addition, the vitamins contained in the medication take an active part in the regeneration of connective tissues in the body.

As the instructions for use indicate, “Ascorutin” is also used for children.

The drug reduces the effects of radiation and also accelerates the process of eliminating toxins and waste, which is important during the recovery period after suffering from influenza, acute respiratory infections and other viral diseases.

Overdose

With long-term use of the pharmaceutical drug in large dosages, it is possible to inhibit the function of the insular apparatus of the pancreatic gland and disrupt the normal functioning of the kidneys. Also, the following symptoms of an overdose of Ascorutin may develop:

epigastric pain;
nausea and vomiting;
profuse skin rashes and itching (predominantly on the flexor surfaces of the upper and lower extremities, abdomen and chest);
increased excitability of the nervous system;
thrombus formation;
increased blood pressure and the development of symptomatic hypertension;
headache.

As therapeutic measures in case of overdose, symptomatic treatment of individual manifestations, gastric lavage, and sorbents are used, since there is no specific antidote for a vitamin drug on the pharmaceutical market.

Drug overdose

With uncontrolled use of the medication, an overdose can quite easily occur. As a rule, this happens if the patient takes 10 or more tablets at a time.

In such situations, a person may experience the following symptoms:

a sharp increase in blood pressure;
disruption of the pancreas;
renal dysfunction.

Also, after taking a large number of pills, the patient often experiences headaches, vomiting, insomnia, diarrhea and nausea. In case of an intentional or accidental overdose of Ascorutin, the victim is recommended to drink 6-7 tablets of activated carbon, and then immediately call an ambulance.

Interaction

The use of acetylsalicylic acid , alkaline drinking or oral contraceptives inhibits the active processes of absorption of the biological components of the drug. The absorption of a pharmaceutical drug is similarly affected by consuming fresh fruit or vegetable juices.

Penicillin increases the ability of the vitamin complex to be absorbed .

The therapeutic effectiveness of ascorbic acid as the main active ingredient of the drug is reduced by the action of Heparin , indirect anticoagulants , antibiotics from the group of aminoglycosides , and sulfonamide drugs. The simultaneous use of Ascorutin with B vitamins, on the contrary, weakens its medicinal properties.

It should also be noted that ascorbic acid increases the serum concentration of salicylates , benzylpenicillin , ethinyl estradiol and tetracycline , which manifests itself in an increased risk of developing any side effects or other unpleasant consequences of conservative sanitation.

The use of Ascorutin for more than 4 weeks (long course of drug therapy) during treatment with cardiac glycosides, non-steroidal anti-inflammatory drugs or antihypertensive drugs may enhance the effect of the latter, which requires special attention, since the adverse consequences can be very disastrous.

Storage conditions and terms

The medicine does not require special storage conditions. It is enough to place the packaging away from ultraviolet rays, where it will be inaccessible to small children.

Temperature range: from +15 to +25 degrees. You should not put the tablets in the refrigerator. The shelf life of the pharmacological product is three years, starting from the date of release. Taking expired medications is not allowed.

It must be remembered that any drugs, even very harmless ones at first glance, cannot be prescribed independently. A specialist will develop a regimen for the treatment or prevention of nosebleeds in children or adolescents.

special instructions

Cuperosis is a disorder of the blood circulation of the skin, which is manifested by unnatural local redness (the area of the nose, cheeks and forehead is primarily affected). Also, there is an unpleasant burning sensation and increased sensitivity of the external integument to exogenous irritants. The pathogenesis of this pathological condition directly depends on the elasticity and fragility of the walls of the bloodstream, congestion, therefore, the cosmetic defect can be eliminated with the help of Ascorutin. For rosacea, tablets allow you to restore a healthy color to your face, get rid of the unaesthetic appearance of protruding capillaries and enrich the structures of the microcirculatory bed with vitamin C.

The pharmaceutical drug also performed well in clinical studies for varicose veins , a chronic lesion of the venous network.

The active components of the drug, ascorbic acid and rutin, improve trophism, normalize regional blood flow, strengthen the walls of the vascular bed, and prevent congestion in the veins of the lower extremities. Accordingly, the tablets are a pathogenetic treatment for a given nosological unit, that is, the medicine affects the mechanism of development of the disease and eliminates the corresponding stages, preventing its genesis.

Of course, the question immediately arises - how to drink Ascorutin for varicose veins ? For this pathology, you should undergo a course of treatment. The dosage used is 2-3 tablets 2 times a day. It is recommended to use the drug both during and after meals to increase the absorption capacity of the active ingredients.

There is no clinically confirmed data that the vitamins included in Ascorutin affect the speed of psychomotor reactions or concentration of attention, therefore driving a car or other complex mechanisms during conservative treatment with the drug is not prohibited.

Description of the drug

Ascorutin belongs to the pharmacological group of drugs with a combined effect. The tablets are sweet and sour in taste, light green in color, beveled and scored. They have a flat-cylindrical shape. Cardboard packaging may contain 10, 50 or 100 tablets. When packaged in PVC or glass bottles - 30 or 50 pieces. The pharmacological agent is approved for over-the-counter release.

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The drug compensates for the deficiency of ascorbic acid and rutin. It is known that vitamins P and C increase resistance to infections, as well as harmful environmental factors. Their combination strengthens connective tissues and promotes cell regeneration. Prescribed for conditions characterized by increased permeability of the vascular wall and capillary fragility.

Rutin is absorbed in the digestive tract, facilitating the transport of ascorbic acid to the small intestine. It is excreted from the body within a maximum of 24 hours with bile or urine. Ascorbic acid in the body is converted to dehydroascorbic acid, after which it is distributed throughout the body. Most goes to the adrenal glands, where the substance is metabolized and then eliminated through the urinary system in the form of oxalate. The remaining part is excreted with bile through the digestive tract.

Analogues of Ascorutin

Level 4 ATX code matches:
Rutin

Venosmin

Indovazin

Venoruton

Troxevasin Neo

Troxevasin

Detralex

Ginkor Gel

Ginkor fort

Vasocket

Anavenol

Troxerutin

Antistax

Venarus

Analogues of the active ingredients of the pharmaceutical drug:

Askorutin D
Askorutin-UBF
Profilaktin S

Analogs for the therapeutic effects of the drug:

Angiovitis
Venarus
Detralex
Cyclo 3 Fort
Aescusan

Analogs

Instead of Ascorutin, you can use analogues containing the same active substances:

Ascorutin D or Ascorutin-UBF. These drugs have the same composition and the same indications for use as Ascorutin.
Prophylactic S. In this preparation, the dosage of ascorbic acid is higher (100 mg), and rutoside, on the contrary, is reduced (25 mg). The medicine is prescribed to prevent or eliminate the deficiency of its constituent compounds, as well as for children over 4 years of age with heavy loads or intensive growth. The drug is in demand for the prevention of acute respiratory infections, as well as for their complex treatment.
AscoRutical forte. These film-coated tablets contain not only rutoside at a dose of 50 mg and vitamin C at a higher dose (200 mg), but also 200 mg of calcium. The remedy is indicated for a- or hypovitaminosis, infectious diseases, as well as problems with blood vessels. It can be given from 5 years of age.

Ascorutin for children

The pharmaceutical drug is actively used in pediatric practice for children over 4 years of age, since the constituent components of the drug are part of the natural metabolism of the human body. At an early age, it is especially important to accurately regulate the number of tablets taken according to the instructions, because hypervitaminosis C for children can lead to such serious consequences as:

hemolysis is the destruction of red blood cells (erythrocytes) in people with a deficiency of the enzyme glucose-6-phosphate dehydrogenase;
deficiency of vitamin B12 , and accordingly macrocytic , megaloblastic anemia (ascorbic acid slows down the absorption of vitamin B12 in the gastrointestinal tract);
damage to tooth enamel;
irreversible deterioration of pancreatic function;
peptic ulcer of the stomach (if vitamin C is taken during treatment with Aspirin ).

Analogs of vitamin preparation

Ascorutin tablets are produced by many Russian pharmaceutical companies. Medicines with the same composition are not produced abroad. The domestic drugs Ascorutin-UBF and Ascorutin-D are considered complete structural analogues of the active ingredients. The difference between the second remedy is the absence of sucrose.

Ascorutin-D tablets can be taken by patients with diabetes. Many domestic and foreign medicines contain one of the active ingredients - ascorbic acid or rutin. Partial analogues are Rutin, Ascovit, Vitamin C, Venoruton. If you need a substitute, you should consult a doctor, since not all analogues of Ascorutin can be used in childhood.

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Ascorutin during pregnancy and lactation

contraindications for taking a pharmaceutical drug during lactation , so you can and should safely use tablets to strengthen the general condition of the body after such a difficult ordeal in a woman’s life as childbirth. The drug has strong antioxidant properties, which will allow you to quickly return to your former athletic shape, form the much-desired waistline and feel much better.

Ascorutin is actively used during pregnancy , since this critical condition in a woman’s life is always accompanied by rapid consumption of internal reserves of useful nutrients and in particular vitamins to build a new organism. Also, the use of the drug “in position” is recommended due to the direct pharmacological effect of the tablets. It is no secret that the circulatory system of the placenta is usually weak, inelastic with a high risk of ruptures and internal hemorrhages, therefore strengthening new capillaries so that the fetus does not experience possible oxygen starvation will never be superfluous.

Ascorutin during menstruation should be taken only in cases where there is an urgent need to suppress the abundance of menstrual flow or its duration. That is, the use of a pharmaceutical drug is really justified only in serious situations (official performance, competitions, exams, and so on). From the age of 18, you can take 2-3 tablets throughout the day, and you need to swallow them immediately with a small amount of water. It is advisable to carry out the manipulation after eating, since the ability to be absorbed by the active ingredients is higher.

A conservative course for menstruation should be started 3-4 days before the expected start of menstrual flow. The duration of the entire therapy should not exceed 10 days, except in situations where a qualified attending physician has given other recommendations. It is advisable to conduct diagnostic blood tests before and after menstruation and consult with a gynecologist based on the results obtained.

Reviews about Ascorutin

The drug is very popular in the modern pharmaceutical market. First of all, because of the cheapness of the drug, because, as a rule, crazy amounts are spent on conservative therapy, and Ascorutin is a pleasant exception. Also, the good reputation of the tablets is maintained due to the wide range of pharmacological actions and the unintended effectiveness of the biologically active components. Vitamin C in combination with rutin and other excipients have a noticeable therapeutic effect, improve well-being and significantly change the indicators of clinical tests towards internationally accepted standards.

A specialized pharmaceutical forum or any thematic Internet resource will also confirm the good reputation of the pharmaceutical drug, because Ascorutin often appears in grateful reviews. This is a medicine that does not hit the wallet hard, but brings a huge number of useful pharmacological effects that are actively used in the conservative treatment of various nosological entities.

Separately, it is worth noting the positive therapeutic effects in chronic vascular pathology . For example, in case of rosacea , after undergoing a course of conservative treatment with Ascorutin, a healthy complexion returns, an unaesthetic blush is eliminated, the problem of protruding capillaries and local hemorrhages disappears without a trace, since the pharmaceutical drug tones and strengthens the walls of the arterial and venous vascular bed, prevents the development of congestion, and improves trophic processes in the skin.

Reviews of Ascorutin for varicose veins also confirm the positive properties of the drug. The therapeutic effects of the active ingredients for this pathology are in many ways similar to the therapeutic properties for rosacea, but there are, of course, some differences. For example, the duration of a course of sanitation for varicose veins covers a slightly longer period of time, since the nosological unit is associated not only with damage to the walls of the venous bloodstream, but also with an increased tendency to form blood clots and thromboembolism .

The biologically active substances included in the Ascorutin tablets allow you to completely restore blood flow even in the most problematic areas, relieve the bloodstream of thrombotic masses, enrich the coagulation system with ascorbic acid and rutin, and reduce the risk of death.

Pigment spots are a common cosmetic problem that develops due to many reasons. The appearance of this pathological condition can be influenced by an increase in the amount of melanin , chronic stress, hormonal imbalances, age-related changes, decreased immunity, and so on. Of course, there is a specialized ointment or an expensive cream that can effectively eliminate the problem, but it is much more advisable to use Ascorutin for age spots, since this vitamin preparation restores and strengthens the functions of the skin, and therefore solves the pathological problem within just two to three weeks.

Reviews about Ascorutin during pregnancy are, as a rule, neutral in nature, since there are no effects visible to the naked eye in this critical condition for a woman. Of course, clinical tests, pathophysiological indicators and other parameters known to qualified gynecologists speak in favor of the use of the drug during pregnancy and lactation, but only specialists can explain this during a personal consultation, because most women do not think about the condition of their own placenta or the presence of internal hemorrhages .

Ascorutin price, where to buy

You can buy a pharmaceutical drug on the territory of the Russian Federation. You should find out how much the tablets cost at the nearest pharmacy kiosks. As a rule, the price of Ascorutin does not exceed 50-70 rubles for 50 pieces.

The price of Ascorutin in Ukraine is slightly lower. The average cost of a package of tablets is approximately 15 hryvnia.

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