Throughout life, a person repeatedly experiences abdominal pain. Under the age of 50, most often the cause of pain is not organic, but functional in nature, when drug therapy is most likely to be effective. The cause may be intestinal colic (in children in the first months of life), irritable bowel syndrome, biliary dyskinesia, dysfunction of the sphincter of Oddi, etc. About a third of cases of functional pain are accompanied by spasm of the smooth muscles of the gastrointestinal tract. This is why antispasmodics are so widely used without a doctor’s prescription. Providing a pronounced analgesic effect and normalizing the functioning of the organ, they, unlike non-narcotic and opioid analgesics, do not interfere with the mechanisms of pain, that is, they do not “erase” the picture of the disease, which is critically important in diagnosis.
Top 8 effective medications for the treatment of gastritis.
May 28, 2021
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Content
- Nolpaza
- Omez
- Nexium
- Gastal
- Rennie
- Maalox
- De-Nol
- Vikair
With gastritis, the gastric mucosa becomes inflamed, and a person experiences symptoms such as nausea, pain, belching, heartburn, etc. Today, gastritis is a very common occurrence, and the disease has become noticeably “younger” and is found even in children. If gastritis is not treated, it becomes chronic and significantly worsens the quality of life.
But you need to understand that there is no universal treatment for gastritis. It can be with high or low acidity, with or without the presence of Helicobacter pylori, with or without concomitant diseases, and many more individual characteristics. Therefore, only a doctor should prescribe drugs for gastritis.
We have compiled a rating of the safest and most effective medications for gastritis, working in three areas: antisecretory agents, antacids and drugs for the treatment of Helicobacter pylori.
The first group of drugs for the treatment of gastritis are drugs that reduce the acidity of gastric juice and the secretory activity of the stomach.
Medicines for stomach pain: what pills to take and how to relieve the pain?
The first thing that needs to be done to improve the patient’s condition is to relieve or reduce discomfort.
On the one hand, analgesics and antispasmodics are necessary, on the other hand, there is a risk of blurring the clinical picture, masking significant symptoms and missing the onset of a serious disease.
Some drugs should not be used before a diagnosis is made, so as not to worsen the patient’s condition. Others are quite safe and recommended for use. It is best to consult a doctor. Only a specialist can accurately determine the diagnosis and prescribe the right medicine.
Nolpaza
These tablets for gastritis not only reduce the amount of hydrochloric acid in the stomach and reduce acidity, but are also indicated in complex therapy (in combination with antibiotics) for Helicobacter pylori. The active substance of Nolpaza, pantoprazole, heals the gastric mucosa during gastritis and ulcers, eliminating unpleasant symptoms. It is recommended to take Nolpaza once or twice a day; the drug is contraindicated for children. We recommend that you study the list of side effects.
Nolpaza
KRKA (KRKA), Slovenia
- gastroesophageal reflux disease (GERD), incl.
erosive and ulcerative reflux esophagitis and symptoms associated with GERD (heartburn, acid regurgitation, pain when swallowing); - erosive and ulcerative lesions of the stomach and duodenum associated with taking NSAIDs; — peptic ulcer of the stomach and duodenum, treatment and prevention; — eradication of Helicobacter pylori in combination with two antibiotics; - Zollinger-Ellison syndrome and other pathological conditions associated with increased gastric secretion. from 92
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Acute pancreatitis has been dealt with. What about chronic?
If the toxic effect on the pancreas does not stop (for example, a person continues to drink excessively) or the organ was very damaged during the first (acute) episode of pancreatitis, the pain returns again and again.
During exacerbations of chronic pancreatitis, blood tests may remain normal. But over time, external signs may appear, which doctors detect by examining the pancreas using ultrasound (ultrasound), X-rays (CT or computed tomography) or magnetic resonance imaging (MRI). These are narrowing of the pancreatic ducts, the appearance of compactions in it - calcifications, as well as the appearance of cysts - bubbles with liquid in place of dead tissue. An examination for suspected chronic pancreatitis is carried out with another important goal - not to miss pancreatic cancer, which may initially be accompanied by the same symptoms.
With constantly renewed inflammation of the pancreas, its function—the secretion of enzymes that digest food—is disrupted over time. As a result, a person is bothered by constant bloating, diarrhea, and the stool becomes greasy (for example, it is difficult to flush from the toilet). This condition - exocrine insufficiency - is most conveniently identified by determining the content of pancreatic elastase (a pancreatic enzyme) in the stool.
Omez
This drug against gastritis perfectly reduces the production of stomach acid, thereby relieving discomfort. Omez became the first drug in its category, the effectiveness and safety of which were confirmed by research. The active substance of the drug is omeprazole. “Omez” forms a protective layer on the gastric mucosa and at the same time heals existing damage - the acute symptoms of gastritis disappear. "Omez" can be taken both for treatment and for preventive purposes (for example, when taking non-steroidal anti-inflammatory drugs) to protect the gastrointestinal tract.
Omez
Dr. Reddy's Laboratories, India
Adults - peptic ulcer of the stomach and duodenum (including prevention of relapses);
- gastroesophageal reflux disease (GERD); - hypersecretory conditions (Zollinger-Ellison syndrome, stress ulcers of the gastrointestinal tract, multiple endocrine adenomatosis, systemic mastocytosis); — eradication of Helicobacter pylori in infected patients with gastric and duodenal ulcers (as part of combination therapy); - prevention and treatment of damage to the mucous membrane of the stomach and duodenum caused by taking NSAIDs (NSAID gastropathy): dyspepsia, erosion of the mucous membrane, peptic ulcer; - prevention of Mendelssohn syndrome (aspiration pneumonitis). Children - treatment of gastroesophageal reflux disease in children over 2 years of age, weighing more than 20 kg; - treatment of duodenal ulcer caused by Helicobacter pylori in children over 4 years of age, weighing more than 20 kg. Safety and effectiveness of the drug for other indications in patients children over 60
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Phosphodiesterase inhibitors (PDE) type IV
These are traditionally widely used antispasmodics: drotaverine hydrochloride and papaverine. Their injectable forms are sold with a prescription, while their tablet forms are available without a prescription. PDE IV is widely present in smooth muscle along the entire length of the intestine, as well as in the biliary and urinary tracts. Thus, blocking PDE IV has a universal antispasmodic effect regardless of the severity of the spasm or its cause. In addition, drotaverine has anti-edematous and anti-inflammatory effects. Drotaverine can be used for acute abdominal pain - both to relieve acute spasms and for long-term treatment of biliary dyskinesia, cholelithiasis, chronic intestinal diseases with spastic syndrome, which are accompanied by colicky or bursting pain. Unlike M-anticholinergics, drotaverine can be used in elderly men with prostate pathology, as well as with concomitant pathology and combined use with other drugs. The therapeutic concentration of drotaverine in plasma when taken orally is achieved after 45 minutes.
Nexium
This is a modern remedy for the treatment of gastritis and reflux disease, which has almost no side effects. Nexium is a proton pump inhibitor that permanently reduces the amount of acid in the stomach. Nexium helps relieve inflammation and heal stomach ulcers, and the effect after treatment lasts a long time. This drug for gastritis is not cheap, but the price is quite justified, especially since it can also be prescribed to children.
Nexium
AstraZeneca, Sweden
Gastroesophageal reflux disease: treatment of erosive reflux esophagitis;
long-term maintenance treatment after healing of erosive reflux esophagitis to prevent relapse; symptomatic treatment of gastroesophageal reflux disease; Peptic ulcer of the stomach and duodenum As part of combination therapy: treatment of duodenal ulcer associated with Helicobacter pylori; prevention of relapses of peptic ulcers associated with Helicobacter pylori. Long-term acid suppression therapy in patients who have suffered bleeding from a peptic ulcer (after intravenous use of drugs that reduce the secretion of gastric glands to prevent relapse). Patients taking NSAIDs for a long time: healing of gastric ulcers associated with taking NSAIDs; prevention of gastric and duodenal ulcers associated with taking NSAIDs in patients at risk. Zollinger-Ellison syndrome or other conditions characterized by pathological hypersecretion of the gastric glands, including from 127
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The next group of drugs are antacids, which eliminate excess acid in the stomach.
Common Causes
Main causes of problems:
- eating large amounts of food, which greatly stretches the stomach tissue and takes a long time to digest;
- intoxication (poisoning) after eating stale food;
- biliary dyskinesia, when the flow of bile into the small intestine is delayed or too fast;
- chronic catarrhal gastritis;
- Pankeratitis.
These are some of the most “harmless” reasons why your stomach is bothering you. But there are more serious pathologies that occur in the body during attacks.
Any acute sudden attack can signal the onset of critical conditions requiring urgent surgical intervention.
You can roughly determine your diagnosis based on the symptoms in the table below: Your doctor will be able to give you an accurate diagnosis.
| DISEASE | SYMPTOMS |
| Exacerbation of chronic gastritis is dangerous by the development of stomach ulcers, phlegmonous and atrophic gastritis, leading to precancerous conditions. |
|
| Peptic ulcer with exacerbation - when the ulcer is perforated, painful shock, internal bleeding and death are possible. |
|
| Renal colic, masquerading as an “acute abdomen ” - there is a high probability of painful shock and collapse. |
|
| Colitis, acute colitis - dangerous by transition to ulcerative colitis, thrombosis and embolism of the abdominal aorta. |
|
| Inflammation of the appendix - if there is a delay in calling an ambulance and applying a heating pad, rupture of the cecum is possible, followed by purulent inflammation of the peritoneum and sepsis. If you have similar symptoms, consult your surgeon. |
|
| Exacerbation of cholecystitis (inflammation of the gallbladder) is dangerous by transition to gangrenous cholecystitis and peritonitis (inflammation of the peritoneum). Diagnoses and advises the therapist. |
|
| Acute pancreatitis - inflammation of the pancreas - is a serious condition that requires immediate treatment in a hospital. |
|
| Myocardial infarction in the abdominal form - a spasm in the heart is often disguised as stomach pain, which poses a direct threat to life, since the provision of medical care occurs too late. If you suspect, consult a cardiologist or cardiac surgeon. |
|
Gastal
"Gastal" are lozenges, so they are always convenient to have on hand and do not need to be washed down with water. It contains magnesium and aluminum, which instantly “quench” heartburn, and the positive effect lasts for about two hours after the tablet is dissolved. "Gastal" not only reduces acidity, but also helps the gastric mucosa to recover. The drug is prescribed in the complex treatment of gastritis and ulcers.
The course of treatment with Gastal is selected by the doctor; you can also use the drug as a one-time “first aid” to relieve the symptoms of heartburn. You can take no more than 8 Gastal tablets per day. It is important that side effects from taking this medication are very rare.
Gastal
TEVA, Ukraine
The combined drug Gastal contains aluminum hydroxide, magnesium carbonate and magnesium oxide.
The combination of active ingredients provides a high antacid (reducing stomach acidity) effect and reducing the possibility of constipation. from 156
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Read also: Top 5 best sorbents for poisoning Rating of the most effective and safe sorbents that help with poisoning and hangover syndrome.
What to do at home
If your gastrointestinal tract suddenly becomes ill, there are several methods that can be used to make you feel better at home. However, it is worth knowing that home remedies have a high risk of worsening the condition. They are used only if you are completely confident in the doctor’s diagnosis. In case of severe attacks that do not subside for more than half an hour, the following is contraindicated:
- warm the abdominal area with a hot heating pad, take a bath, as this can lead to internal bleeding, rupture of the inflamed intestine, perforation of the ulcer and death;
- give water and medicine if you suspect a perforation of the ulcer, which is accompanied by profuse sweat, vomiting, severe panic, and after that - a false improvement in the condition.
Non-drug ways to relieve an attack
With an accurate diagnosis, the following methods of relieving unpleasant sensations are allowed:
- If the diagnosis of “pancreatitis” has been established, then during an exacerbation it is allowed to apply ice to the pancreas area, since this slows down the development of acute inflammation, with refusal to eat for a day or two. You need to drink water.
- In case of exacerbation of gastritis, urgent home help consists of rinsing the epigastrium (if the diagnosis of acute gastritis is beyond doubt) with a solution of baking soda (a teaspoon per liter of water).
Acute sudden attacks in the abdomen are a common symptom of threatening diseases of internal organs: heart, liver, gall bladder, rupture of the cecum filled with pus, perforation of the epigastrium due to an ulcer, internal bleeding. In such cases, the first thing you need to do, without wasting a minute, is to urgently call an ambulance.
Learn more about the causes of abdominal pain and methods of treating it from the video:
Useful articles on the topic: What can pain under the left rib in front indicate? Pain in the right side under the ribs in front - what could it be?
This article has been verified by a current qualified physician, Victoria Druzhikina, and can be considered a reliable source of information for site users.
Bibliography
1. https://www.zakonprost.ru/content/base/part/431434 https://ivo.garant.ru/#/document/70349708/paragraph/11:0
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Rennie
"Rennie" are heartburn tablets with different flavors (they are even available without sugar). Rennie contains calcium carbonate and magnesium hydroxycarbonate. In the stomach, this gastritis medicine neutralizes excess acid. At the same time, the drug increases the production of mucus, which protects the stomach and heals damage to the mucosa. "Rennie" begins to act very quickly - literally three to five minutes after administration. The big advantage of these tablets is that they can be taken by pregnant women (and heartburn is a common occurrence during this period).
Rennie
Bayer Bitterfeld GmbH, Germany
The drug is taken for diseases of the gastrointestinal tract associated with increased acidity of gastric juice
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Cellular mechanism of pain
Smooth muscle cells are mainly found in the large intestine. There are significantly fewer of them in the small intestine. The mechanism of cell contraction depends on the concentration of calcium ions in the cytoplasm. The sources of calcium are the extracellular space, connected to the cytoplasm through calcium (slow) membrane channels, as well as the intracellular depot. The release of calcium causes the muscle cell to contract. The contraction of muscle cells forms a spasm and the person feels pain.
The process of muscle contraction is most often triggered by the mediator acetylcholine, binding to muscarinic cholinergic receptors (M-cholinergic receptors). Thus, blockade of M-cholinergic receptors leads to a decrease in tone and relaxation of smooth muscles (and therefore helps relieve abdominal pain). This, in particular, is the basis for the mechanism of action of a group of drugs called M-anticholinergics.
The interaction of calcium with calmodulin leads to the interaction of actin with myosin and cell contraction. CAMP (cyclic adenosine monophosphate) and cGMP (cyclic guanosine monophosphate) weaken the interaction of calcium with calmodulin and also impede the entry of calcium ions into the cell. The level of cAMP and cGMP is controlled by phosphodiesterase (PDE), which destroys excess of these nucleotides. Thus, if you reduce the activity of PDE, the concentration of calcium ions in the cytoplasm will decrease and the tone of the muscle cell will decrease.
Based on the described mechanisms for regulating the calcium concentration inside the muscle cell, which are disrupted under pathological conditions and lead to spasm, the main groups of antispasmodics have been created:
- M-anticholinergics (atropine, hyoscine butyl bromide).
- PDE IV inhibitors (drotaverine).
- Blockers of calcium release from intracellular stores or sodium channel blockers (mebeverine).
- Calcium channel blockers.
Maalox
"Maalox" for gastritis is presented in the form of chewable tablets and suspensions. This drug neutralizes hydrochloric acid and increases the pH level in the stomach. The active ingredients of Maalox are magnesium hydroxide and hydrated aluminum oxide. Also, this medicine for gastritis envelops the stomach, works as an adsorbent, and protects the mucous membrane from acid. "Maalox" is prescribed for gastritis, reflux esophagitis and ulcers. Before taking these tablets for gastritis, we recommend that you carefully read the contraindications.
Maalox
Chinoin (Sanofi-Sintelabo), Hungary
- peptic ulcer of the stomach and duodenum in the acute phase;
- acute gastroduodenitis; — chronic gastroduodenitis with normal or increased secretory function in the acute phase; - hiatal hernia; - reflux esophagitis; - dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, sour belching after errors in the diet, excessive consumption of ethanol, coffee, nicotine, etc.; - dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, sour belching (and their prevention), resulting from the use of certain medications (including NSAIDs, corticosteroids). from 20
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The last group is bismuth preparations, which are prescribed for the treatment of Helicobacter pylori.
Typical pathologies
Acute pain
If it appears suddenly, accompanied by vomiting and fever, then this may be a symptom of poisoning, infection, or surgical disease. There is a special form of myocardial infarction (abdominal), in which acute pain occurs not in the heart, but in the epigastrium. All of these conditions are life threatening. In order not to waste time, you need to urgently call “03”.
Strong pain
Occurs in acute gastritis, exacerbation of peptic ulcer, complications of ulcer (penetration, perforation), pancreatitis, in the initial stage of appendicitis. If it appears, you need to urgently consult a doctor or call “03” to rule out surgical pathology (we recommend asking a surgeon a question).
Sharp
Characteristic of tumors of the epigastrium, pancreas, penetration of the ulcer (its penetration into nearby organs), the development of adhesive processes in the tissues surrounding the ulcer. Periodic is characteristic of gastritis, duodenitis, exacerbation of peptic ulcer. The diagnosis is established using FGDS. All these symptoms are a reason to consult a specialist.
Aching
Constant aching pain is characteristic of tumors of the stomach, pancreas, penetration of the ulcer (its penetration into nearby organs), and the development of adhesive processes in the tissues surrounding the ulcer. Periodic spasms are characteristic of gastritis, duodenitis, exacerbation of peptic ulcer disease. The diagnosis is established using FGDS.
Hungry pain in the stomach
Occurs with increased acidity. It is observed in gastritis, peptic ulcers and is quickly eliminated by antacids (phosphalugel, Rennie, Almagel). These drugs relieve discomfort, but do not treat the underlying disease. To establish the cause, you should contact a gastroenterologist or therapist.
During pregnancy
The cause may be acute and chronic diseases of the gastrointestinal tract, toxicosis, hormonal changes, and after 20 weeks - displacement of internal organs by the growing uterus. To find out the nature of the ailment, you need to consult a therapist. Pregnant women can take No-shpu and non-absorbable antacids (Gatracid, Maalox, Almagel), other drugs - strictly as prescribed by the doctor. Consult your gynecologist.
De-Nol
This medication contains 120 mg of bismuth per tablet. "De-Nol" destroys the bacterium Helicobacter pylori and protects the stomach from acid. De-Nol works best in combination with antibiotics. This drug must be prescribed by a doctor and is approved for children over 4 years of age. The cost of De-Nol is high, and while taking it you may experience constipation, and your stool may turn dark.
De-nol
Astellas Pharma Europe, Russia
De-Nol is an antiulcer drug containing the active substance – bismuth subcitrate.
De-Nol belongs to the group of astringent drugs, however, it has a multifaceted effect, influencing various parts of the pathogenesis of peptic ulcer disease. The main pharmacological effects of the drug include astringent, antimicrobial and gastrocytoprotective effects. from 294
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Gastritis
Gastritis is a lesion of the mucous membrane. The symptoms of this pathology are the following: heaviness and pain in the stomach, nausea, heartburn. Pain sensations are localized in the ribs. With chronic gastritis, after eating food you feel heaviness and aching pain.
This pathology develops due to an increased level of acidity, which is why the stomach is affected by the microorganism Helicobacter. This disorder poisons the body, provokes the development of inflammation of the gastric mucosa, which causes tissue atrophy.
Vikair
This medicine for gastritis contains not only bismuth from Helicobacter pylori, but also plant components (buckthorn bark, calamus rhizome extract), as well as magnesium carbonate and sodium bicarbonate. This composition of Vikair makes it both an antispasmodic, an antacid and a drug with an astringent and laxative effect. The medicine has low cost and excellent effectiveness, so it is popular in the treatment of gastritis. But it is worth remembering that Vikair is contraindicated during pregnancy and children.
Vikair
Nota bene!
When a client asks for a remedy for abdominal pain, it is necessary to exclude urgent situations in order to send the sufferer to a doctor in time. These include:
- Severe pain that prevents you from sleeping or doing anything, lasts longer than 1-2 hours.
- Severe abdominal pain is accompanied by vomiting.
- Severe pain is accompanied by elevated body temperature - 38.5°C and above.
- Severe pain is accompanied by loss of consciousness.
- Severe abdominal pain in a pregnant woman.
- The abdominal muscles are tense and the stomach is as hard as a board.
- Diarrhea mixed with bright red blood.
- The stool is dark and tarry.
- Vomiting blood.
- Abdominal pain is accompanied by vomiting, diarrhea and severe dehydration.
