Compound
The Raunatin tablet, coated with a special coating, contains 2 mg. active compound of rauwolfia alkaloid , as well as auxiliary compounds: cerulesum, sugar, calcium stearate, cross-povidone, glucose, stearic acid, basic magnesium carbonate, gelatin, aerosil, medium molecular weight polyvinylpyrrolidone , talc, pigment titanium dioxide, beeswax, dyes E 104 and KF-6001.
The drug belongs to the group of sympatholytics , as well as antihypertensive drugs. The question of what Raunatin tablets are for can be answered as follows - the drug is indicated for hypertension .
Special instructions and recommendations
Despite the natural composition and a slight range of restrictions, the drug can only be taken as prescribed by a doctor. The specialist also determines the optimal dosage, dosage regimen and duration of the therapeutic course with Raunatin for a particular patient.
If surgery is planned, the pills should be stopped a few days before the date of the intended operation.
In patients with diagnosed coronary artery disease, the medication can provoke angina attacks. In such situations, it is necessary to consult a doctor about temporarily stopping treatment or adjusting the daily dosage of Raunatin.
Since the drug is characterized by the presence of sedative and sedative properties, at the beginning of therapy it is recommended to refrain from driving a car and other activities that require quick reactions and extreme concentration. If there is no effect on cognitive functions, you can return to your usual lifestyle.
Raunatin can cause a decrease in concentration, so it is better not to drive during treatment with the drug
Pharmacodynamics and pharmacokinetics
Since Raunatin contains components such as rauwolfia alkaloids , it has a pronounced hypotensive as well as antiarrhythmic effect . The drug has a beneficial effect on the health of patients suffering from arterial hypertension , both mild and moderate.
It is noteworthy that the sedative effect of this drug is less pronounced than its antiarrhythmic and hypotensive properties . However, in comparison with Reserpine, Raunatin is in most cases much better tolerated, although the pronounced hypotensive effect of this drug occurs more slowly.
Pharmacodynamic characteristics
Blood pressure tablets Raunatin have a pronounced hypotensive effect. The therapeutic effect is due to the ability of the drug to reduce the concentration of the hormone norepinephrine, serotonin and dopamine.
Raunatin lowers blood pressure smoothly and gradually, which is considered an advantage of the drug, as well as its ability to activate glomerular filtration processes localized in the renal canals, increasing blood flow in the renal apparatus.
The tablets stabilize the psycho-emotional state of the user, have a moderate sedative effect, relieve anxiety and tension, stabilize the heart rhythm, eliminating manifestations of arrhythmia.
The drug has a cumulative effect, so therapeutic results become noticeable after 1.5-2 weeks of treatment. Blood pressure levels are fully stabilized after a 2-3 month course of Raunatin tablets.
Raunatin has a cumulative effect, so you should complete the full course of treatment with the drug
Contraindications
It is not recommended to use the drug for:
- depression;
- organic myocardial damage ;
- arterial hypotension;
- the patient's age is under 18 years;
- coronary circulatory insufficiency ;
- aortic defects;
- pregnancy (third trimester);
- nephrosclerosis;
- stomach and duodenal ulcers;
- hypersensitivity.
What does Raunatin help with?
Doctors recommend taking Raunatin for high blood pressure, users who have the following clinical indications:
- Diseases of a cardiac nature;
- Arterial hypertension;
- Rapid heartbeat (tachycardia);
- Hypertonic disease;
- Thyrotoxicosis, accompanied by increased blood pressure, rapid pulse and heart rhythm disturbances;
- Diseases of the gastrointestinal tract of an infectious or parasitic nature.
In most cases, tablets are prescribed to patients with diagnosed hypertension to reduce blood pressure, improve blood supply to the kidneys, and strengthen the cardiovascular and central nervous systems.
Raunatin tablets, instructions for use (Method and dosage)
In accordance with the instructions for use of Raunatin, tablets are taken after meals. In order not to harm the patient’s health, the patient should strictly adhere to the drug dosage regimen, and, in addition, the recommended dosages. On the first day, take one tablet, i.e. 2 mg each. rauwolfia alkaloids before bed.
On the second day - one tablet twice a day, the next day - three tablets, thus gradually increasing the dosage to six pieces. After a two-week therapeutic course of treatment, the dosage is also gradually reduced to a maximum of two tablets per day.
When use is contraindicated
Raunatin for high blood pressure is strictly prohibited for use by patients with the following clinical contraindications:
- Bronchial asthma;
- Nephrosclerosis;
- Ulcerative lesions of the gastrointestinal tract;
- Individual intolerance and excessive sensitivity to the components included in the tablets;
- Hypotonic disease (low blood pressure);
- Severe form of depression;
- Aortic defects;
- Violation of coronary circulation processes;
- Biliary dyskinesia;
- Myocardial pathologies;
- Colitis;
- Parkinson's disease;
- Cerebral atherosclerosis;
- Pheochromocytoma;
- Severe heart failure;
- Epileptic syndrome;
- Bradycardia (slow heart rate).
Despite the fact that the drug is good for blood pressure, using the tablets to treat minor patients, women expecting the birth of a baby or breastfeeding is strictly contraindicated!
The drug should be taken strictly as prescribed by the doctor
Raunatina price, where to buy
The average price of Raunatin (pack of 50 tablets) varies from 100 to 120 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Raunatin tablets p.p.o.
2 mg 50 pcs. Wifitech ZAO 109 rub. order - Raunatin tab. p/o 2 mg 50 pcs LLC FC Zdorovye
109 rub. order
Pharmacy Dialogue
- Raunatin (tablet p/o 2 mg No. 50)Health/Ukraine
90 rub. order
- Raunatin (tablet p/o 2 mg No. 50) Vifitech CJSC
94 RUR order
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PaniPharmacy
- Raunatin tablets Raunatin tablets.
p/o 0.002g No. 20 Ukraine, Health LLC 28 UAH. order - Raunatin tablets Raunatin tablets. p/o 0.002g No. 10 Ukraine, Health LLC
13 UAH order
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Side effects from taking the drug
Treatment with Raunatin may cause the following side effects:
- Rhinitis;
- Impaired liver function;
- Depressive states;
- Increased sweating;
- Decreased libido and erectile dysfunction in representatives of the stronger sex;
- Chronic fatigue syndrome;
- Lethargy, apathy, decreased performance, drowsiness during the daytime;
- Dyspeptic disorders;
- Skin itching and allergic rashes such as urticaria;
- Swelling and dryness of the mucous membranes;
- Painful sensations localized under the shoulder blade;
- Manifestations of heart failure.
If you detect at least one of the adverse reactions listed above, you should stop taking the pills and seek advice from a medical specialist! It may be necessary to reduce the daily dose of the drug or select a more suitable analogue.
Raunatin 2 mg 50 pcs. film-coated tablets (Ukraine)
pharmachologic effect
Antihypertensive herbal remedy.
Composition and release form Raunatin 2 mg 50 pcs. film-coated tablets (Ukraine)
Tablets - 1 tablet:
- Active component: Raunatin (Rauwolfia alkaloids) in terms of 100% content of the total alkaloids - 0.002 g;
- Kernel excipients: Sugar (sucrose) - 0.0346 g; Potato starch - 0.0290 g; Glucose monohydrate (dextrose monohydrate) - 0.0136 g; Calcium stearate - 0.0008 g; Kernel mass - 0.08 g;
- Shell excipients: Sugar (sucrose) - 0.0617012 g; Basic magnesium carbonate (magnesium hydroxycarbonate) - 0.0153066 g; Low molecular weight medical polyvinylpyrrolidone (povidone) - 0.0010564 g; Titanium dioxide - 0.0009680 g; Aerosil (colloidal silicon dioxide) - 0.0008880 g; Vaseline oil (liquid paraffin) - 0.0000384 g; Beeswax - 0.0000256 g; Talc - 0.0000158 g.
10 tablets per blister pack.
3 or 5 blister packs along with instructions for use are placed in a cardboard pack.
Description of the dosage form
The tablets are round, biconvex, white coated.
Directions for use and doses
Inside, after eating. Treatment should be carried out under the supervision of a physician.
On the first day, take 1 tablet (0.002 g) at night; on the second day - 1 tablet 2 times a day; on the third day - 3 tablets.
The maximum daily dose is 6 tablets per day. After achieving a therapeutic effect (after 10-14 days), the dose is gradually reduced to 1-2 tablets per day. Maintenance dose - 1 tablet per day.
The course of treatment is 3-4 weeks, repeated courses are recommended by a doctor.
Pharmacodynamics
Raunatin is the sum of alkaloids from rauwolfia roots, the content of which in terms of dry matter is at least 90%. Alkaloids are represented by reserpine, serpentine, ajmaline and others.
It has a hypotensive effect and antiarrhythmic effect, as well as a calming effect on the central nervous system. The latter is less pronounced than that of reserpine, but the drug is not inferior to reserpine in its hypotensive effect. In some cases, Raunatin is better tolerated than reserpine. The hypotensive effect of the drug develops more slowly than that of reserpine.
Pharmacokinetics
It is well absorbed from the gastrointestinal tract, but more slowly than reserpine, so the hypotensive effect develops gradually. Approximately 60% of the drug is excreted in feces and 8% in urine. The half-life is 45-168 hours.
Indications for use Raunatin 2 mg 50 pcs. film-coated tablets (Ukraine)
Arterial hypertension of the first degree of severity.
Contraindications
Hypersensitivity to the components of the drug, arterial hypotension, severe bradycardia, coronary circulatory failure, organic myocardial lesions, aortic defects, gastric and duodenal ulcers, nephrosclerosis, depression, sucrase/isomaltase deficiency, congenital fructose intolerance, glucose-galactose malabsorption, pregnancy, period of breastfeeding, age up to 18 years.
Carefully:
Cardiac ischemia; patients with diabetes and people on a low-carbohydrate diet.
If you have one of the listed diseases, be sure to consult your doctor before taking the drug.
Application Raunatin 2 mg 50 pcs. film-coated tablets (Ukraine) during pregnancy and breastfeeding
contraindicated.
special instructions
In patients with coronary heart disease, an increase in angina attacks is possible. If pain in the heart area occurs, it is necessary to reduce the dose of Raunatin or interrupt treatment (for 1-3 days) and consult a doctor.
Before planned surgery, the drug should be discontinued several days before surgery. If emergency surgery is necessary under general anesthesia in patients taking Raunatin, premedication with atropine is necessary.
The drug should not be used before an electropulse therapy session. The dose of the drug should be reduced gradually.
Patients with diabetes should take into account that one tablet contains about 0.139 g of carbohydrates (0.012 XE).
Impact on the ability to drive vehicles and operate machinery
During treatment with the drug, patients should refrain from driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Overdose
Symptoms: pronounced decrease in blood pressure up to collapse, increased sweating, general weakness.
Treatment: symptomatic - gastric lavage, taking activated charcoal. If there is a pronounced decrease in blood pressure, if the patient collapses, lay the patient down and raise his legs; if necessary, intravenous administration of rheopolyglucin or phenylephrine solution or other vasoconstrictors is indicated. There are no specific antidotes.
Side effects Raunatin 2 mg 50 pcs. film-coated tablets (Ukraine)
Possible allergic reactions, swelling of the nasal mucosa, increased sweating, asthenia, bradycardia, pain in the heart, worsening angina, development of depression or worsening of its course, decreased libido.
If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Drug interactions
Can be used simultaneously or sequentially with other antihypertensive drugs (ganglion blockers, hydrochlorothiazide, hydralazine and others).
Prescribe with caution in combination with quinidine, guanethidine, cardiac glycosides, beta-blockers (risk of increased severity of negative chrono- and dromotropic effects).
The drug can enhance the effect of ethanol and barbiturates on the central nervous system.
What to do in case of overdose
The use of Raunatin at high blood pressure in large quantities, uncontrolled and for a long time can lead to an overdose, manifested by the following characteristic symptoms:
- Weakness, lethargy, apathy, decreased performance;
- Fainting conditions;
- A sharp decrease in blood pressure (hypotonic crisis);
- Excessive sweating.
You can help the patient by inducing artificial vomiting and allowing him to take sorbents. A good effect is achieved by diuresis and the use of diuretics, which allow toxic substances to be eliminated through the renal apparatus.
In case of fainting, an emergency call is necessary. Doctors will detoxify the body using IVs and, if necessary, provide artificial ventilation. After stabilization of the patient's condition, symptomatic treatment is prescribed.
An overdose of the drug can cause weakness and sweating
Substitutes for Raunatin
The following analogues of Raunatin are presented in pharmacy chains:
- Cinepres;
- Adelfan;
- Reserpine;
- Triseride K;
- Bretylate;
- Acenosine;
- Normatens;
- Brinerdine;
- Kristepin;
- Rawolfia extract.
Despite the difference in composition, the drugs listed above have a similar therapeutic effect to Raunatin, which allows them to be used as substitutes.
Raunatin for hypertension is an effective drug that normalizes blood pressure, heartbeat, and improves the general condition of the patient. To obtain the most pronounced positive result and prevent side effects, you should take the tablets in the dosage recommended by the doctor, strictly following all the recommendations of a medical specialist.