Furadonin tablets: instructions for use, price, reviews for cystitis. Indications for use

pharmachologic effect

The medicine belongs to the group of nitrofurans and is an antimicrobial drug. Bactericidal and bacteriostatic effects are achieved by disrupting the process of protein synthesis in bacteria and the permeability of the cell membrane. Furadonin demonstrates activity against a number of gram-positive and gram-negative bacteria (these are Shigella , streptococci , staphylococci , Escherichia coli , etc.). Effective in the development of urinary tract infections.

During treatment with this drug, bacterial resistance rarely develops, but with prolonged use of the drug, resistance is still possible.

The most pronounced drug activity is observed in acidic urine. If the urine pH is 8 or more, the bactericidal activity of the product is noticeably reduced.

Answering the question whether Furadonin is an antibiotic or not, it should be noted that this drug is not an antibiotic.

Instructions for use of Furadonin

The medicine must be taken after meals with a sufficient amount of water. The tablets should not be chewed, but simply swallowed whole.

The therapeutic dosage of the drug per day is 0.3 g, maximum 0.6 g for adult patients. This dose is divided into 3-4 doses per day.

For the treatment of mild forms of the infectious process, it is indicated to use 50 mg three times a day.

In acute conditions, a course lasting 7-10 days is prescribed. If no therapeutic effect is observed after the end of the course, the drug is not extended.

To prevent exacerbations of pathological processes and prophylaxis, the medicine is taken in an amount of 1-2 mg/kg body weight.

For children, the therapeutic dose is calculated individually. Per 1 kg of weight there are 5-7 mg of the drug. The total amount is divided into 4 doses during the day.

To make treatment with an antimicrobial agent more effective, it is necessary to consume more protein foods during the course.

Indications for use of Furadonin

Before starting treatment, the patient must understand what Furadonin tablets are and what they help with. The following indications for the use of Furadonin are determined:

infectious-inflammatory diseases of the urinary tract, which are provoked by microorganisms sensitive to Furadonin ( urethritis , pyelonephritis , cystitis , pyelitis );
For the purpose of prevention, it is used for cytoscopy , urological surgical interventions, catheterization.

Before you start treatment with Furadonin, you should find out from a specialist what these tablets are for and how to take them.

Contraindications

The following contraindications to the use of the drug are determined:

high sensitivity to the drug;
chronic renal failure ;
chronic heart failure of the second or third degree;
cirrhosis of the liver;
acute porphyria ;
hepatitis in chronic form.

Also contraindications to taking Furadonin are the period of pregnancy and lactation, the age of the child under 1 month.

Contraindications for Furadonin

The following conditions are contraindications to taking an antimicrobial agent:

Allergic reaction to the active or additional component.
Severe heart failure.
Liver cirrhosis.
Chronic course of hepatitis.
Serious liver disorders.
Acute form of porphyria.

In addition, the drug is prohibited for use by children under 1 month of age and by women while pregnant and breastfeeding.

Side effects

During treatment with this drug, the following side effects may develop:

allergic manifestations: chills, rash , Quincke's edema , etc.;
disturbances in the functioning of the respiratory system: cough, eosinophilia , pain in the chest, pulmonary infiltrates, decreased respiratory function, asthma attacks in people with a history of bronchial asthma
disturbances in the functions of the digestive system: vomiting, anorexia , nausea, epigastric discomfort, in rare cases - hepatitis , jaundice , diarrhea ;
disturbances in the functioning of the nervous system: dizziness, headache , drowsiness ;
disorders of the hematopoietic system: granulocytopenia , leukopenia , thrombocytopenia , agranulocytosis , anemia ;
skin reactions: erythema , dermatitis ;
other disorders: arthralgia , anaphylaxis , myalgia , drug fever, superinfection of the genitourinary tract.

If the side effects described above occur during treatment, you should definitely consult a doctor.

Side effects

The use of Furadonin may cause side effects such as:

Disturbance of the digestive tract - nausea, vomiting, emaciation, pain in the epigastric region. Signs of hepatitis, jaundice and diarrhea are rarely observed.
Dysfunction of the respiratory system - cough, chest discomfort, eosinophilia are observed, signs of asthma develop in people suffering from asthma attacks.
Headache, dizziness, insomnia or drowsiness.
Allergic reaction - skin rash, hyperemia, itching. Urticaria and angioedema are sometimes possible.
Changes in laboratory blood values.
Other manifestations include fever, myalgia, and arthralgia.

Furadonin tablets, instructions for use (Method and dosage)

Instructions for use of Furadonin stipulate that the drug should be taken with plenty of liquid, preferably taken after meals. Since the tablets have a bitter taste, chewing them is not recommended, especially for children. The highest daily dose for adult patients is 0.6 g, a single dose is 0.3 g.

Instructions for use for adult patients include taking 0.1-0.15 g of medication 3-4 times a day.

For uncomplicated infectious diseases, Furadonin should be taken 50 mg three times a day.

Patients with acute urological diseases take the drug for 7 to 10 days. If no improvement in the patient’s condition is observed during the period of therapy, further treatment with the drug is not advisable. In order to prevent relapses of diseases and for prophylaxis, the drug should be taken in a dose of 1-2 mg per 1 kg of weight.

Instructions for use for children

For children, the medicine is prescribed at the rate of 5-7 mg per 1 kg of child weight per day. The total dose should be divided into 4 doses. With long-term use for the purpose of prevention, it is enough to take a dose of 1 mg per 1 kg of weight per day.

Those who are interested in how to take Furadonin should note that the effect of the drug on the body becomes more pronounced in an acidic environment, so it is recommended to prefer protein foods during treatment.

The medicine Furadonin is widely used for cystitis. A specialist will tell you in detail how to take Furadonin for cystitis in each specific case. Treatment of cystitis with Furadonin tablets is practiced for both acute and chronic forms of the disease. As a rule, taking 3-4 tablets of the drug per day is indicated (unless the doctor has prescribed a different regimen on how to take tablets for cystitis).

Composition and release form

The drug is dispensed from the pharmacy in several dosage forms:

Tablets have a thin soluble film coating.
Suspension - mainly used for the treatment and prevention of children.
Powder - represents small granules of a light shade. Used to prepare a solution.

All dosage forms are intended for oral administration. Packaged in cardboard packaging with attached instructions for use.

The active substance is nitrofurantoin. Its quantity varies depending on the form of release. Auxiliary components: calcium stearate, starch, silicon dioxide and more.

Interaction

You should not simultaneously take Furadonin and antacid preparations containing magnesium trisilicate , as well as nalidixic acid , as this reduces the antibacterial effect of the drug.

You cannot combine the medicine with fluoroquinolones .

Drugs that block tubular secretion due to a decrease in the concentration of nitrofurantoin in the urine reduce the degree of antimicrobial effect of the drug and also increase the concentration of this substance in the blood, which leads to increased toxicity of the drug.

The antibacterial effect of Furadonin decreases in alkaline urine. Therefore, there is no need to take this remedy in parallel with medications that increase urine pH.

The process of removing Furadonin from the body is reduced by sulfinpyrazone and probenecid , therefore, the simultaneous use of these drugs is undesirable.

Interaction with other drugs

It is prohibited to take the medicine together with fluoroquinolones.

The antimicrobial effect of the drug is reduced when taken simultaneously with antacid medications containing magnesium trisilicate and nalidixic acid.

Drugs that block tubular secretion also lead to a decrease in the pharmacological effect. They, with increasing concentrations of nitrofurantoin, can increase the toxicity of the drug.

The therapeutic effect of the antimicrobial drug is suppressed in alkaline urine. Therefore, it is forbidden to combine the medicine with other drugs that increase the pH of urine.

It is not recommended to combine Furadonin with Probenecid and Sulfinpyrazone, as they inhibit the process of drug elimination.

special instructions

It should be taken into account that in people suffering from hypovitaminosis B , anemia , diabetes , electrolyte imbalance during treatment with Furadonin, the likelihood of peripheral neuropathy .

Not used for the treatment of prostatitis , purulent paranephritis .

To reduce the risk of side effects from the gastrointestinal tract, the drug should be taken with food or milk.

Nitrofurantoin should not be prescribed together with medications that can cause renal dysfunction.

Furadonin's analogs

Level 4 ATX code matches:
Furagin

Furamag

There are no structural analogues of Furadonin. There are a number of analogues of this drug according to the mechanism of therapeutic effect, these drugs are:

Furasol
Furagin
furazidine
Furamag

Furadonin or Furagin - which is better?

Furagin belongs to the same group (nitrofuran derivatives). The indications for use of both drugs are similar, and at the same time they provoke the development of almost identical side effects. It is generally accepted that Furagin is a milder medicine. But the final decision on the choice of drug should be made only by a specialist, which requires consultation with a doctor.

Furadonin during pregnancy and lactation

Furadonin during pregnancy increases the risk of developing hemolytic anemia in the baby. The active substance passes through the placenta and has a toxic effect on the fetus. In some cases, Furadonin is used to treat pregnant women after 12 weeks, but only strictly as directed and after comparing the possible risks and benefits.

If you are breastfeeding , you should not use this medicine because its active substance passes into breast milk.

Reviews about Furadonin

Reviews about Furadonin are mostly positive: patients write about the high effectiveness of the product. Reviews of Furadonin for cystitis indicate that this remedy allows you to get rid of unpleasant symptoms within a few days. There are also positive reviews that the drug is relatively cheap.

However, quite often there is information from patients about the manifestation of side effects: headaches , nausea , vomiting , dizziness , etc.

Furadonin

The incidence of adverse reactions noted when taking nitrofurantoin is given in the following gradation: very often (≥ 1/10), often (≥ 1/100, < 1/10), infrequently (≥ 1/1,000, < 1/100) , rare (≥ 1/10,000, < 1/1,000), very rare (< 1/10,000) and frequency unknown (cannot be estimated from available data).

Infectious and parasitic diseases:

frequency unknown - pseudomembranous colitis, superinfection of the genitourinary tract, most often caused by
Pseudomonas aeruginosa
or
Candida spp.
Blood and lymphatic system disorders:

rarely - megaloblastic anemia, leukopenia, granulocytopenia or agranulocytosis, thrombocytopenia, hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency.

Immune system disorders:

very rarely - lupus-like syndrome (rash, eosinophilia, fever, arthralgia), in which an increase in two or more parameters is observed in the blood serum - antinuclear antibodies, antibodies to smooth muscle or to the glomerular basement membrane and Coombs' reaction. In some cases - angioedema, anaphylaxis, autoimmune reactions associated with chronic changes in the lungs or liver.

Nervous system disorders:

often - headache; rarely - increased intracranial pressure; frequency unknown - dizziness, asthenia, nystagmus, drowsiness; peripheral polyneuropathy (including optic neuritis), the first symptoms of which are a feeling of numbness and burning in the legs, muscle weakness.

Disorders of the respiratory system, chest and mediastinal organs:

very rare: acute and chronic hypersensitivity reactions of the lungs, characterized by fever, eosinophilia, cough, chest pain, shortness of breath (“nitrofurantoin pneumonia”), interstitial changes in the lungs, broncho-obstructive syndrome, pleurisy. Pulmonary infiltrate or consolidation and pleural effusion may appear within hours or days of initiation of therapy; they usually resolve after stopping the drug. Subacute or acute pulmonary symptoms, including pulmonary fibrosis, may develop insidiously in patients with prolonged therapy; fibrosis may be irreversible, especially if therapy is continued after the onset of symptoms (see section "Contraindications").

Gastrointestinal disorders

: often - nausea, vomiting, lack of appetite; rarely - diarrhea, abdominal pain, pancreatitis, inflammation of the salivary glands.

Disorders of the liver and/or biliary tract:

rarely - hepatitis, cholestatic jaundice (dose-independent and disappear after discontinuation of the drug).

Disorders of the skin and subcutaneous tissues:

often - allergic reactions (skin rashes, urticaria, itching); very rarely - exfoliative dermatitis, polymorphic erythema.

Genital and breast disorders

: very rarely - a passing disorder of spermatogenesis.

Others

: rarely - joint pain, reversible hair loss.

Furadonin price, where to buy

The price of Furadonin 50 mg tablets is on average 60 rubles. per pack 10 pcs. The average price of Furadonin 100 mg is 180 rubles. per pack 20 pcs.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine
Online pharmacies in KazakhstanKazakhstan

ZdravCity

Furadonin tab.
50 mg 10 pcs YuzhPharm LLC RU 51 rub. order
Furadonin tablets 100 mg 20 pcs. Olainfarm JSC
162 RUR order
Furadonin Avexima tablets 50 mg 20 pcs. JSC Irbitsky Chemical Plant
112 rub. order
Furadonin Avexima tablets 100 mg 20 pcs. JSC Irbitsky Chemical Plant
177 RUR order
Furadonin Avexima tablets 50 mg 10 pcs. JSC Irbitsky Chemical Plant
70 rub. order

Pharmacy Dialogue

Furadonin Avexima tablets 50 mg No. 20 Irbitsky HFZ
108 RUR order
Furadonin Avexima tablets 50 mg No. 10 Irbitsky HFZ
67 RUR order
Furadonin (tab. 50 mg No. 20) YuzhPharm
70 rub. order
Furadonin Avexima (tab. 100 mg No. 20) Irbitsky Chemical Plant
180 rub. order
Furadonin tablets 100 mg No. 20Olainfarm OA
182 RUR order

Pharmacy24

Furadonin 0.1g No. 20 tablets AT "Olainfarm", Latvia
49 UAH. order

PaniPharmacy

Furadonin tablets Furadonin tablets 0.1g No. 20 Latvia, Olainfarm JSC
51 UAH order