Dentinox is a German drug produced in the form of a gel and solution for topical use. The sphere of influence is the oral cavity. Accordingly, due to its composition, it has an analgesic and anti-inflammatory effect on the affected mucosal tissues.
1 g of gel or solution contains up to 150 mg of chamomile extract, about 3.4 mg of lidocaine, and 3.2 mg of polyconadol 600. The solution is distributed in dark dropper bottles. The gel is packaged in tubes with a capacity of 10 g.
Pharmacological properties of the drug Dentinox-gel n
Local anesthetic of plant origin. When using the herbal remedy of chamomile infusion, the anesthetic lidocaine and polidocanol 600 (macrogol lauryl ether) in a low dose specially selected for children, pain during teething of baby teeth is eliminated. Chamomile infusion: a herbal remedy with anti-inflammatory effects in a standardized pharmaceutical form. Lidocaine hydrochloride: an anesthetic used topically in a safe dose (0.34%). Polidocanol 600 (macrogol lauryl ether): local anesthetic, is well retained on the oral mucosa and has a long-lasting therapeutic effect. Dentinox-Gel N is better distributed and stays on the mucous membrane longer. The drug does not cause dental caries.
Dentinox gel N gel 10g No. 1
Name
Dentinox gel N gel in tubes 10g per pack. No. 1
Description
Homogeneous opalescent gel.
Main active ingredient
Lidocaine+lauromacrogol 400+chamomile flower extract
Release form
Gel
pharmachologic effect
Dentinox® Gel N is a combined preparation that, along with a herbal component (tincture of chamomile flowers), which has an anti-inflammatory and soothing effect on gum irritation, also contains local anesthetics in a concentration approved for use in children and infants. Lidocaine provides a quick analgesic, but short-term effect, which occurs a few minutes after application of the drug to the gums. The analgesic effect of polidocanol occurs later, but is longer lasting. Together they have a quick and long-lasting effect at low dosages. The use of the drug ensures the eruption of the first teeth, all milk teeth, as well as molars without pain and complications. Dentinox ® Gel N prevents the occurrence of local inflammatory reactions, allows you to largely avoid gum irritation and the formation of excessive salivation. The xylitol and sorbitol contained in the preparation do not cause dental caries. Dentinox® Gel N does not contain preservatives or sugar.
Indications for use
It is used for short-term relief of pain during the eruption of the first teeth, all milk and molars, as well as to prevent inflammation and irritation of the gums.
Directions for use and doses
Using a clean finger or a clean cotton swab, apply a pea-sized drop of Dentinox ® Gel N to the area of the gum where the tooth is emerging and rub in lightly. Repeat the procedure 2-3 times a day, especially after meals and before bed. If necessary, use the drug during the entire period of eruption of baby teeth, and later molars.
Use during pregnancy and lactation
Since this drug is used exclusively to relieve pain during the first teething in children, there is no information on the use of this drug during pregnancy and lactation.
Precautionary measures
Contraindicated in patients with rare hereditary fructose intolerance. Avoid getting the drug in your eyes! Dentinox® Gel N is applied locally to the gums. When applied to the oral mucosa, local irritation is possible due to the presence of propylene glycol. This drug contains a small amount of ethanol (alcohol), less than 100 mg per dose, which is due to the active component of the drug - chamomile tincture, which is produced by extraction with ethanol. Caution should be exercised when using Dentinox® Gel N to patients with damage to the mucous membrane in the area of application, if it is larger in size than is usually observed during teething, since in this case increased systemic absorption is possible.
Interaction with other drugs
not known. The effect on the ability to drive vehicles and operate machinery has not been studied.
Contraindications
Hypersensitivity to the active components or to one of the excipients included in the drug, as well as to Asteraceae or to local anesthetics of the amide group.
Compound
1 g of gel contains: Active substances: tincture of chamomile flowers 150 mg, lidocaine hydrochloride 3.4 mg, polidocanol 600 (macrogol lauryl ether) 3.2 mg. Excipients: propylene glycol, xylitol, 70% sorbitol solution, sodium edetate, 10% sodium hydroxide solution, carbomer (974P), polysorbate 20, sodium saccharin, menthol (levomenthol), purified water.
Overdose
There are no known cases of overdose or intoxication with lidocaine when using Dentinox Gel N. Since the drug is applied topically to the gums, when used in accordance with the therapeutic prescription, overdoses are excluded. In case of accidental ingestion of a large amount of the drug (more than one whole package at a time), disorders of the gastrointestinal tract (abdominal pain and nausea) may occur. When taking a very high dose of lidocaine orally (several packages of the drug at the same time), symptoms of depression of the central nervous system, bradycardia, depression of myocardial function, cardiogenic shock, and respiratory depression may be observed. Treatment is symptomatic: oxygen therapy is carried out, anticonvulsants, vasoconstrictors are prescribed, and for bradycardia - anticholinergics.
Side effect
When assessing side effects, the following frequency scale was used: very often: ≥1/10 often: ≥1/100,
Storage conditions
Store at a temperature not exceeding 25°C in a protected place. Keep out of the reach of children.
Buy Dentinox gel N gel in tubes 10g per pack. No. 1 in pharmacy
Price for Dentinox gel N gel in tubes 10g per pack. No. 1
Instructions for use for Dentinox gel N gel in tubes 10g per pack. No. 1
Application
For stomatitis or pain, Dentinox is applied as a solution as follows:
- The hands of the person who will apply the product must first be washed with soap.
- Next, depending on the application method, drop the solution onto a cotton swab or onto a clean finger. 3 drops are enough.
- Smear the gums in the teething area with light massage movements for 30 seconds - 1 minute.
If necessary, both types, both Dentinox baby in drops and the gel, can be alternated and used during this period of teething, both primary and primary. When using gel the principle is the same:
- Wash your hands thoroughly.
- Apply the product onto your finger or cotton swab. Literally one drop, which is the size of a small pea, is enough.
- Rub the mixture into the gum where the tooth is erupting. Do this without pressure, as carefully, carefully and easily as possible.
Next, wash your hands from the product and close the bottle or tube. The procedure can be performed up to 3 times a day and only after meals, as well as before bedtime. The product is applied only in the presence of pain, if the child has a hard time with the teething process. If you are unsure about the regimen for using the medication, consult your doctor first.
Make sure that the tip of the dropper or the area around the entrance of the tube does not touch the skin. Otherwise, there is a risk of contamination of the contents.
If you forget to apply Dentinox Baby to the treatment area, then under no circumstances should you apply a double dosage. This can cause severe side effects. If a dose is missed, simply continue to use the medication according to the standard regimen after the next feeding.
Contraindications, side effects
Instructions for use of Dentinox show that direct contraindications to the use of the product are:
- Allergy to chamomile extract and asteraceae;
- Allergy to lidocoine or related pain relievers;
- Allergy to other components of the drug;
- Fructose intolerance.
The use of Detinox with other foods and drinks does not require any restrictions. But you should follow the application rule: only after meals or just before bed. Avoid contact of the solution or gel with the eyes.
The use of the drug during lactation is not prescribed in the instructions, but it is known that it is used to relieve pain during the first eruption of different types of teeth. There is no information on use during pregnancy, since no relevant studies have been conducted.
If a larger amount of the drug was applied to the gums, then the side effects appear with greater force. In such an incident, the use of the drug is canceled completely, as well as its analogues. Next, show the child to the doctor and describe the situation. Side effects may appear in the form of local allergic-type reactions:
- Irritation;
- Hives;
- Increased sensitivity of the treated area.
In case of overdose, the following may also occur:
- Tissue swelling;
- Erythema;
- Angioedema;
- Bronchospasm;
- Anaphylactic shock (this occurs in exceptional cases).
Systemic exposure is unlikely since only a small amount of lidocaine enters the bloodstream. But nervous excitement, dizziness, loss of consciousness, insomnia, respiratory paralysis, decreased blood pressure, cardiac arrest, bradycardia, and myocardial depression can still occur with oral administration (that is, when a large amount of the drug is ingested).
If a side effect occurs, you should immediately stop using the drug, since lidocaine is considered an allergenic substance and can, under certain conditions, cause serious pathological conditions. If signs of angioedema appear, then the use of oral antihistamines is prohibited due to the risk of suffocation. It is necessary to immediately call an ambulance, which will help eliminate the consequences of an overdose or the development of an allergic reaction.
In general, there are no known cases of overdose or side effects at the moment, but if any undesirable reactions occur on the part of the child’s body, the use of the drug should be stopped. It is worth understanding that a child’s body is more sensitive to allergens and reacts to them more acutely.
Indications for use of the drug
Primarily due to the composition, it has an antiseptic and anesthetic effect. The drug also has an anti-inflammatory effect. It acts exclusively locally and is used strictly according to the instructions. Thanks to the composition, it significantly facilitates the process of teething of primary and primary teeth, as well as incisors. Accordingly, the drug is used in infants and children of the first year of life during teething in order to simultaneously prevent inflammatory processes and pain.
The drug is safe in its composition and does not cause allergic or other negative reactions. No side effects were identified in the instructions or during the research process. The gel can be stored for up to 5 years, but the solution can be stored for only 3. But after opening the package, the shelf life is reduced to 1 year, which in principle is quite sufficient for a specific drug and the age of the child.
In simpler terms, the medication is used mainly for the prevention of inflammatory-infectious pathologies, increases local immunity thanks to chamomile extract, and also has a time-limited analgesic effect. Dentinox gel helps eliminate irritation by acting on nerve receptors in the soft tissues of the gums. This, in turn, improves the overall well-being of the baby.
Composition of the drug and its effect
As mentioned earlier, Dentinox gel contains substances such as lidocaine, chamomile extract and lauromacrogol-600. These are the active components of both forms of the drug. Excipients are represented mainly by sorbitol, xylitol, propylene glycol, carbomer (974 R), sodium hydroxide 10% solution, polysorbate 20, sodium edetate, sodium saccharin, menthol (levomenthol), purified water.
Lidocaine has an anesthetic effect on the teething areas. There is a slight freezing effect, which allows you to quickly relieve even intense pain in a baby. Together with lauromacrogol-600 it shows not only high efficiency, but also a prolonged effect.
Chamomile extract has antimicrobial and anti-inflammatory effects. This is a natural component of the drug that has a gentle effect on the mucous membranes. Its action is quite prolonged.
The component lauromacrogol 600 has a local anesthetic effect. This substance is well distributed over the surface of the oral mucosa. This action helps to provide a long-lasting therapeutic effect. Helps enhance the analgesic activity of lidocaine without developing negative effects.
It is prohibited to use the drug outside the oral cavity due to the ineffectiveness and lack of appropriate instructions that Dentinox contains.
The result of the complex effect is painless eruption of the first incisors and the molars that follow them. Dentinox dental gel helps prevent gum irritation, as well as inflammation of the oral mucosa. That is, it helps to prevent stomatitis and severe pain in the aftermath.
Traditionally, the medication is used to effectively stimulate tooth growth, as well as to prevent dental pathologies. Dentinox contains sweeteners that do not cause caries, but at the same time help facilitate the application process. Accordingly, the drug does not contribute to the destruction of enamel. Also, the product does not contain preservatives, and therefore is completely safe for the child’s body.
