Instructions for use FLUCINAR ointment

Pharmacodynamics and pharmacokinetics

Flucinar ointment, like the gel, has antiexudative, antipruritic, antiallergic and anti-inflammatory effects.

Its effect is achieved by inhibiting phospholipase A2, reducing PG synthesis and releasing macrophage chemotactic factor.

This ensures the migration of macrophages and lymphocytes to the area of ​​inflammation, stabilization of the lysosome membrane, prevention of the release of lysosomal enzymes , blocking the release of biologically active components from sensitized mast cells, histamine basophils, and so on.

It has been established that the activity of this drug is 40 times hydrocortisone

Interactions of the drug Flucinar

No interactions were observed with external use of GCS. However, it should be noted that during treatment with the drug it is not recommended to vaccinate against smallpox, as well as carry out other types of immunization (especially with prolonged use on large areas of the skin) due to the possible lack of an adequate immunological response in the form of the production of appropriate antibodies. Flucinar may enhance the effect of immunosuppressive drugs and weaken the effect of immunostimulating drugs.

Indications for use

Flucinar gel and ointment are used for external lesions. Therefore, the main indications for the use of ointment and gel are the treatment of severe inflammatory and allergic diseases of the skin and mucous membranes:

• neurodermatitis;
• seborrheic dermatitis;
• eczema;
• psoriasis;
• lichen planus.

Special instructions for the use of the drug Flucinar

Do not use continuously for more than 2 weeks. With prolonged use on large areas of the skin, the incidence of side effects and the possibility of developing edema, arterial hypertension, hyperglycemia, and decreased body resistance increases. With external use of the drug, the following are possible: a decrease in the production of ACTH by the pituitary gland due to inhibition of the adrenal-pituitary gland system, a decrease in the level of cortisol in the blood and the development of Cushing's syndrome, which disappears after stopping the use of the drug. If an infection develops at the site of application of the ointment, appropriate antibacterial or antifungal treatment should be carried out. If symptoms of infection do not disappear, you must stop using the drug while the infection is being treated. Avoid applying the drug to the eyelids or the skin around the eyes in patients with angle-closure and open-angle glaucoma, as well as in patients with cataracts due to a possible increase in the symptoms of the disease. On the skin of the face, axillary and groin area, use only in case of special need, since there may be increased absorption and a high risk of side effects (telangiectasia, perioral dermatitis), even after short-term use. The drug should be used with caution in the presence of subcutaneous tissue atrophy, mainly in the elderly. Use during pregnancy and lactation. As a result of animal studies, it has been confirmed that GCS have a teratogenic effect even when used in small doses. The teratogenic effect in animals was also confirmed when strong corticosteroids were applied to the skin. Controlled studies have not been conducted to evaluate the possible teratogenic effects in women during pregnancy when applied topically to the skin. Flucinar can be prescribed during pregnancy only if the potential benefit of the drug for the mother outweighs the risk to the fetus. The drug is absolutely contraindicated in the first trimester of pregnancy. It is not known whether fluocinolone acetonide can pass into breast milk after topical use. After oral administration of corticosteroids, which can potentially cause effects in a newborn baby, their significant concentrations in breast milk have not been determined. You need to be especially careful when using Flucinarau in women during breastfeeding. Children. The drug is not used in children under 2 years of age. The ability to influence the reaction rate when driving a vehicle or working with other mechanisms. The drug does not limit mental and motor abilities, as well as the ability to drive vehicles and machinery.

Instructions for use of Flucinar (Method and dosage)

Flucinar ointment instructions for use recommend applying it externally. In this case, the area of ​​application of the ointment is determined by the degree of damage.

Flucinar gel instructions for use also recommend applying to the affected area, gently rubbing, up to 2 times a day, no more than 2 g.

For psoriasis, Flucinar N ointment is often used, which can be applied under an occlusive dressing. The duration of treatment with the drug on the skin on the face should not exceed 1 week, on other places - up to 2 weeks.

Treatment of children over 2 years of age should be carried out with extreme caution, no more than once a day, on small areas of the skin.

Side effects of the drug Flucinar

The following side effects may occur: acne, post-steroid purpura, inhibition of epidermal growth, subcutaneous tissue atrophy, dry skin, excessive body hair growth or alopecia, depigmentation or hyperpigmentation of the skin, atrophy and loss of skin integrity, telangiectasias, perioral dermatitis, furunculosis, atrophic streaks (striae), secondary infections. In some cases, the following may appear: urticaria, itching, burning, contact dermatitis, pstantic-papular rash or exacerbation of existing skin changes. The use of ointment under an occlusive dressing, given the increased absorption, can cause a pronounced systemic effect, which manifests itself in the form of edema, arterial hypertension, and a decrease in the body's resistance to infections. When applied externally to the skin of the eyelids, it can sometimes contribute to the development of cataracts or glaucoma.

Analogs

Level 4 ATC code matches:
Gistan-N

Sinalar

Avecourt

Mesoderm

Momederm

Betazon

Silkaren

Elokom

Sinaflan

Celestoderm

Cutivate

Advantan

Betamethasone

Beloderm

Mometasone Furoate

Uniderm

Momat

The main ointment analogues: Akriderm, Metipred, Dermovate and Lokoid .

Reviews of Flucinar

There are often reviews of Flucinar ointment on the Internet, but opinions about its effectiveness are very ambiguous. Patients often report that the drug helps well at the initial stage of treatment, but further effects may be unexpected.

If for some people this remedy helps to quickly get rid of the symptoms of psoriasis - for which Flucinar ointment is used most often - then others note a significant weakening of the effect or its complete disappearance.

In addition, you can come across reports that the drug helps eliminate unwanted symptoms well, but after stopping its use they arise with renewed vigor. When the ointment is not used for a while, itching, flaking and redness begin to appear again.

Sometimes patients suffering from psoriasis use Flucinar N to treat new plaques. They say that applying the ointment under the bandages helps get rid of spots and other manifestations of the disease. At the same time, other users clarify whether Flucinar ointment is hormonal or not, and how often it can be used.

Unfortunately, often users, even without knowing exactly what Flucinar ointment is intended for, apply it to the skin for a variety of skin lesions: itching, redness, peeling and irritation.

The use of this drug without a doctor’s prescription for serious disorders does not help solve the problem, but, on the contrary, complicates the course of the disease. Moreover, this ointment is not a completely safe product, and its uncontrolled use can cause numerous side effects. This can be avoided by timely contacting a specialist and mandatory compliance with all his appointments.

Pharmacological properties of the drug Flucinar

Framacodynamics. Fluocinolone acetonide is a synthetic fluorinated corticosteroid for external use. When used as an ointment at a concentration of 0.025%, it has a pronounced anti-inflammatory, antipruritic, antiallergic and vasoconstrictor effect. It has lipophilic properties and is well absorbed through the skin. Already after applying 2 g of ointment, the production of ACTH by the pituitary gland may decrease as a result of inhibition of the adrenal-pituitary gland system. The mechanism of the anti-inflammatory effect of fluocinolone acetonide has not been fully studied and suggests that this drug affects the inflammation process by inhibiting the production of prostaglandins and leukotrienes as a result of a decrease in the activity of phospholipase A2 and the release of arachoidonic acid from cell membrane phospholipids. The antiallergic effect is manifested by inhibiting the development of local hypersensitivity reactions. As a result of local vasoconstrictive action, it reduces the risk of developing exudative reactions. Reduces protein synthesis and collagen deposition. Accelerates the breakdown of proteins in the skin and weakens proliferative processes. Pharmacokinetics. Fluocinolone acetonide penetrates well through the stratum corneum of the epidermis, where it gradually accumulates and is detected even 15 days after application. Does not biotransform in the skin. After absorption, it is systemically biotransformed, mainly in the liver. It is excreted in the urine and in smaller quantities in bile, mainly in the form of a compound with glucuronic acid, and also in a small amount unchanged. Absorption of fluocinolone acetonide through the skin is enhanced when applied to sensitive skin - areas of anatomical folds of the body and face, as well as to skin with damaged epidermis or inflammation. The use of an occlusive dressing causes an increase in skin temperature and humidity, which also leads to increased absorption of fluocinolone acetonide. In addition, absorption increases with frequent use of the drug and over large areas of the skin. Absorption through the skin occurs faster in adolescents than in adults.

Flucinar price, where to buy

The price of Flucinar ointment is 216-250 rubles.

The price of Flucinar gel varies between 220-260 rubles.

You can buy the drug in almost any Russian pharmacy without a prescription.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Flucinar ointment 0.025% 15gJelfa SA
  RUB 297 order
• Flucinar gel 0.025% 15gJelfa SA

  RUB 297 order

• Flucinar N ointment d/nar. approx. tube 15gJelfa SA

  RUB 217 order

Pharmacy Dialogue

• Flucinar N ointment (tube 15g)Jelfa SA

  RUB 226 order

• Flucinar ointment (tube 0.025% 15g)Jelfa

  RUB 323 order

• Flucinar gel (tube 15g)Jelfa

  RUB 323 order

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Pharmacy24

• Flucinar 0.025% 15 g gel Elfa A.T. Pharmaceutical Plant, Poland
  106 UAH order
• Flucinar 0.25 mg/1 g 15 g ointment Elfa A.T. Pharmaceutical Plant, Poland

  104 UAH order

• Flucinar N 15 g ointment Farmzavod Elfa A.T., Poland

  111 UAH order

PaniPharmacy

• Flucinar N ointment Flucinar N ointment 15g Poland, Jelfa

  115 UAH order

• Flucinar gel Flucinar gel 0.025% 15g Poland, Jelfa

  116 UAH order

• Flucinar ointment Flucinar ointment 0.025% 15g Poland, Jelfa

  116 UAH order

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Composition and release form

in tubes of 15 g; in a cardboard pack 1 tube.

in tubes of 15 g, in a cardboard pack 1 tube.