Gastroenterologist "SM-Clinic" spoke about the course of gastritis


September 22, 2020

Gastritis is an inflammation of the gastric mucosa, leading to disruption of its secretory function

Gastritis is an inflammation of the gastric mucosa, leading to disruption of its secretory function. During the inflammatory process, food entering the stomach is poorly digested, which leads to impaired absorption of nutrients.

Chronic gastritis affects about 60-85% of the world's population, including young people aged 18 to 35 years. Due to the modern rhythm of life, gastritis has begun to occur more often in children aged 5 to 13 years. Among all diseases of the gastrointestinal tract, gastritis is the most common; a common “marker” of gastritis is the appearance of pain in the stomach. American scientists Marshall and Warren received the Nobel Prize for their discovery of the infectious mechanism of gastritis, caused by the microorganism Helicobacter pylori. This microorganism has been identified in the mucous membranes of many patients suffering from chronic gastritis.

Top 8 effective medications for the treatment of gastritis.

May 28, 2021
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Content
  • Nolpaza
  • Omez
  • Nexium
  • Gastal
  • Rennie
  • Maalox
  • De-Nol
  • Vikair

With gastritis, the gastric mucosa becomes inflamed, and a person experiences symptoms such as nausea, pain, belching, heartburn, etc. Today, gastritis is a very common occurrence, and the disease has become noticeably “younger” and is found even in children. If gastritis is not treated, it becomes chronic and significantly worsens the quality of life.

But you need to understand that there is no universal treatment for gastritis. It can be with high or low acidity, with or without the presence of Helicobacter pylori, with or without concomitant diseases, and many more individual characteristics. Therefore, only a doctor should prescribe drugs for gastritis.

We have compiled a rating of the safest and most effective medications for gastritis, working in three areas: antisecretory agents, antacids and drugs for the treatment of Helicobacter pylori.

The first group of drugs for the treatment of gastritis are drugs that reduce the acidity of gastric juice and the secretory activity of the stomach.

General signs of gastritis

Regardless of the type (acute or chronic), it always manifests itself as pain in the epigastric region (only its nature differs). Pain appears after eating or, conversely, from hunger. Other symptoms from the digestive system are possible:

  • belching;
  • nausea;
  • vomit;
  • bowel disorders.
  • Symptoms in adults are more severe than in children. In children, attacks are often accompanied by weakness, fever, and bruises under the eyes. Parents may confuse the first signs of gastritis with poisoning.

    Another noticeable symptom of many types of this disease is a white (less often yellow) coating on the tongue. It is not cleaned during normal hygiene procedures. In most cases, plaque indicates a decrease in acidity.

    Nolpaza

    These tablets for gastritis not only reduce the amount of hydrochloric acid in the stomach and reduce acidity, but are also indicated in complex therapy (in combination with antibiotics) for Helicobacter pylori. The active substance of Nolpaza, pantoprazole, heals the gastric mucosa during gastritis and ulcers, eliminating unpleasant symptoms. It is recommended to take Nolpaza once or twice a day; the drug is contraindicated for children. We recommend that you study the list of side effects.

    Nolpaza
    KRKA (KRKA), Slovenia

    - gastroesophageal reflux disease (GERD), incl.
    erosive and ulcerative reflux esophagitis and symptoms associated with GERD (heartburn, acid regurgitation, pain when swallowing); - erosive and ulcerative lesions of the stomach and duodenum associated with taking NSAIDs; — peptic ulcer of the stomach and duodenum, treatment and prevention; — eradication of Helicobacter pylori in combination with two antibiotics; - Zollinger-Ellison syndrome and other pathological conditions associated with increased gastric secretion. from 92

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    Digestive processes in the human body

    Our stomach is the most vulnerable organ of the digestive system. The most important and complex digestive processes take place in it:

    • Mixing of food occurs in the stomach - this is a mechanical process.
    • Next, the breakdown of food occurs there - this is a chemical process.
    • And absorption of nutrients. If at least one of these processes goes wrong, the entire digestive system suffers, and all further stages of its work are disrupted.

    Most often, the inner wall of the stomach is damaged, its mucous membrane, where the production of the most important components of digestion occurs - gastric juice and protective mucus.

    Omez

    This drug against gastritis perfectly reduces the production of stomach acid, thereby relieving discomfort. Omez became the first drug in its category, the effectiveness and safety of which were confirmed by research. The active substance of the drug is omeprazole. “Omez” forms a protective layer on the gastric mucosa and at the same time heals existing damage - the acute symptoms of gastritis disappear. "Omez" can be taken both for treatment and for preventive purposes (for example, when taking non-steroidal anti-inflammatory drugs) to protect the gastrointestinal tract.

    Omez
    Dr. Reddy's Laboratories, India

    Adults - peptic ulcer of the stomach and duodenum (including prevention of relapses);
    - gastroesophageal reflux disease (GERD); - hypersecretory conditions (Zollinger-Ellison syndrome, stress ulcers of the gastrointestinal tract, multiple endocrine adenomatosis, systemic mastocytosis); — eradication of Helicobacter pylori in infected patients with gastric and duodenal ulcers (as part of combination therapy); - prevention and treatment of damage to the mucous membrane of the stomach and duodenum caused by taking NSAIDs (NSAID gastropathy): dyspepsia, erosion of the mucous membrane, peptic ulcer; - prevention of Mendelssohn syndrome (aspiration pneumonitis). Children - treatment of gastroesophageal reflux disease in children over 2 years of age, weighing more than 20 kg; - treatment of duodenal ulcer caused by Helicobacter pylori in children over 4 years of age, weighing more than 20 kg. Safety and effectiveness of the drug for other indications in patients children over 60

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    Types of damage to the mucous membrane

    Gastritis can also be classified according to the degree of change in the gastric mucosa. The mildest form is superficial, when the inflammatory process affects only the upper part of the mucosa. More dangerous forms include the following:

  • erosive – leading to the appearance of scars;
  • atrophic – destroying the cells responsible for the production of hydrochloric acid;
  • hyperplastic – causing thickening of the mucosa and provoking the growth of polyps and cysts.
  • Although hyperplastic gastritis is characterized by the appearance of neoplasms, they are predominantly benign.
    The atrophic form often leads to stomach cancer. Each of these types can be focal or diffuse: the first covers a small area of ​​the mucous membrane (although there may be several of them), the second spreads over its entire surface.

    Nexium

    This is a modern remedy for the treatment of gastritis and reflux disease, which has almost no side effects. Nexium is a proton pump inhibitor that permanently reduces the amount of acid in the stomach. Nexium helps relieve inflammation and heal stomach ulcers, and the effect after treatment lasts a long time. This drug for gastritis is not cheap, but the price is quite justified, especially since it can also be prescribed to children.

    Nexium
    AstraZeneca, Sweden

    Gastroesophageal reflux disease: treatment of erosive reflux esophagitis;
    long-term maintenance treatment after healing of erosive reflux esophagitis to prevent relapse; symptomatic treatment of gastroesophageal reflux disease; Peptic ulcer of the stomach and duodenum As part of combination therapy: treatment of duodenal ulcer associated with Helicobacter pylori; prevention of relapses of peptic ulcers associated with Helicobacter pylori. Long-term acid suppression therapy in patients who have suffered bleeding from a peptic ulcer (after intravenous use of drugs that reduce the secretion of gastric glands to prevent relapse). Patients taking NSAIDs for a long time: healing of gastric ulcers associated with taking NSAIDs; prevention of gastric and duodenal ulcers associated with taking NSAIDs in patients at risk. Zollinger-Ellison syndrome or other conditions characterized by pathological hypersecretion of the gastric glands, including from 127

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    The next group of drugs are antacids, which eliminate excess acid in the stomach.

    Acute and chronic gastritis

    Acute is the nightmare of any person who has been diagnosed with this disease. During exacerbation the following are observed:

    • severe pain;
    • vomit;
    • bloating;
    • temperature increase;
    • internal bleeding.

    Moreover, it is worth noting that acute gastritis can be caused by alcohol, spicy food, taking antibiotics, allergies or severe stress. If the disease is neglected, there is a high probability of developing ulcers.

    Chronic - it is distinguished by its “secrecy”, so it cannot be immediately recognized. The disease proceeds unnoticed and worsens only when taking potentially dangerous foods and medications. In the event of an attack, patients experience similar symptoms as during an exacerbation.

    Gastal

    "Gastal" are lozenges, so they are always convenient to have on hand and do not need to be washed down with water. It contains magnesium and aluminum, which instantly “quench” heartburn, and the positive effect lasts for about two hours after the tablet is dissolved. "Gastal" not only reduces acidity, but also helps the gastric mucosa to recover. The drug is prescribed in the complex treatment of gastritis and ulcers.

    The course of treatment with Gastal is selected by the doctor; you can also use the drug as a one-time “first aid” to relieve the symptoms of heartburn. You can take no more than 8 Gastal tablets per day. It is important that side effects from taking this medication are very rare.

    Gastal
    TEVA, Ukraine

    The combined drug Gastal contains aluminum hydroxide, magnesium carbonate and magnesium oxide.
    The combination of active ingredients provides a high antacid (reducing stomach acidity) effect and reducing the possibility of constipation. from 156

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    Read also: Top 5 best sorbents for poisoning Rating of the most effective and safe sorbents that help with poisoning and hangover syndrome.

    Causes

    It is quite difficult to name the exact cause of gastritis. However, doctors still identify several factors that provoke the appearance and further development of this unpleasant disease:

    • passive lifestyle;
    • improper and irregular nutrition;
    • bad habits;
    • taking dangerous drugs;
    • constant stress.

    pixabay.com/carlosfs05

    Rennie

    "Rennie" are heartburn tablets with different flavors (they are even available without sugar). Rennie contains calcium carbonate and magnesium hydroxycarbonate. In the stomach, this gastritis medicine neutralizes excess acid. At the same time, the drug increases the production of mucus, which protects the stomach and heals damage to the mucosa. "Rennie" begins to act very quickly - literally three to five minutes after administration. The big advantage of these tablets is that they can be taken by pregnant women (and heartburn is a common occurrence during this period).

    Rennie
    Bayer Bitterfeld GmbH, Germany

    The drug is taken for diseases of the gastrointestinal tract associated with increased acidity of gastric juice
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    Treatment of acidity disorders

    If there are signs of low acidity, replacement therapy with enzyme preparations is prescribed. Its main task is to normalize the production of pepsin. Preparations containing acedin-pepsin help with this. Drug stimulation of gastric juice secretion is also necessary.

    If the diagnostic results reveal increased acidity, the patient is prescribed antacids. They neutralize acid, weaken the activity of pepsin, and in some cases have an enveloping effect. To eliminate symptoms, medications are recommended that stimulate gastrointestinal motility and relieve spasms of smooth muscles. Additionally, you can use folk remedies - herbs, flax seeds, potato juice.

    Maalox

    "Maalox" for gastritis is presented in the form of chewable tablets and suspensions. This drug neutralizes hydrochloric acid and increases the pH level in the stomach. The active ingredients of Maalox are magnesium hydroxide and hydrated aluminum oxide. Also, this medicine for gastritis envelops the stomach, works as an adsorbent, and protects the mucous membrane from acid. "Maalox" is prescribed for gastritis, reflux esophagitis and ulcers. Before taking these tablets for gastritis, we recommend that you carefully read the contraindications.

    Maalox
    Chinoin (Sanofi-Sintelabo), Hungary

    - peptic ulcer of the stomach and duodenum in the acute phase;
    - acute gastroduodenitis; — chronic gastroduodenitis with normal or increased secretory function in the acute phase; - hiatal hernia; - reflux esophagitis; - dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, sour belching after errors in the diet, excessive consumption of ethanol, coffee, nicotine, etc.; - dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, sour belching (and their prevention), resulting from the use of certain medications (including NSAIDs, corticosteroids). from 20

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    The last group is bismuth preparations, which are prescribed for the treatment of Helicobacter pylori.

    This is interesting

    It should be noted that Helicobacter pylori is one of the most common human infections; residents of megacities are more likely to suffer.
    According to Russian scientists, the prevalence of this infection in Moscow is 60.7 - 88%, in St. Petersburg - 63.6%, in the cities of Eastern Siberia - up to 90% (data from the TsNIIG GBUZ MKNTs DZM published in the journal "Treating Doctor" in 2021). The less processed and the simpler the product is prepared, the healthier it is for the stomach. Boiled or baked meat is healthier for the stomach than sausages and frankfurters.

    Drink water 30-40 minutes before meals (a glass of warm water drunk before meals normalizes stomach acidity). At the same time, do not drink during meals or immediately after it, but at least after half an hour or an hour.

    Chew your food thoroughly. If food enters the stomach in large pieces, this creates additional stress, causing discomfort and bloating.

    In the evening, try to eat at least three hours before bedtime, and preferably four. Don't sleep after a big lunch.

    Don't get used to enduring pain and discomfort. If you begin to “feel” your stomach, immediately consult a gastroenterologist.

    Numerous studies show that the main problem in the development of gastritis of the stomach is damage to the mucous membranes by the bacterium Helicobacter pylori. And eliminating contamination with this bacterium is the gold standard of gastroenterology today. It is clear that no diet in the world can get rid of Helicobacter. This requires complex therapy.

    De-Nol

    This medication contains 120 mg of bismuth per tablet. "De-Nol" destroys the bacterium Helicobacter pylori and protects the stomach from acid. De-Nol works best in combination with antibiotics. This drug must be prescribed by a doctor and is approved for children over 4 years of age. The cost of De-Nol is high, and while taking it you may experience constipation, and your stool may turn dark.

    De-nol
    Astellas Pharma Europe, Russia

    De-Nol is an antiulcer drug containing the active substance – bismuth subcitrate.
    De-Nol belongs to the group of astringent drugs, however, it has a multifaceted effect, influencing various parts of the pathogenesis of peptic ulcer disease. The main pharmacological effects of the drug include astringent, antimicrobial and gastrocytoprotective effects. from 294

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    Diagnostics

    • General clinical analysis of blood and urine
    • Analysis of stool for coprogram
    • Biochemical blood test (liver tests, cholesterol, alkaline phosphatase)
    • ECG
    • X-ray of the chest organs in 2 projections
    • X-ray of the esophagus, stomach with barium mixture
    • Ultrasound of the hepatobiliary system
    • 24-hour pH monitoring in the lower esophagus and stomach
    • EGDS
    • Non-invasive tests for the determination of Helicobacter pylori (respiratory)

    Vikair

    This medicine for gastritis contains not only bismuth from Helicobacter pylori, but also plant components (buckthorn bark, calamus rhizome extract), as well as magnesium carbonate and sodium bicarbonate. This composition of Vikair makes it both an antispasmodic, an antacid and a drug with an astringent and laxative effect. The medicine has low cost and excellent effectiveness, so it is popular in the treatment of gastritis. But it is worth remembering that Vikair is contraindicated during pregnancy and children.

    Vikair

    What kind of disease is this

    Gastritis is an inflammatory process that occurs on the inner lining of the stomach. This disease causes severe damage to the mucous membrane, which leads not only to unpleasant sensations, but also disrupts the process of food absorption. As a result, not only the stomach, but also the intestines suffer from gastritis. If you contact a gastroenterologist, the doctor will definitely say that this disease occurs in almost every second Russian.

    It often happens that people do not even suspect they have gastritis. And if discomfort in the stomach does occur, many people use painkillers or other drugs that relieve symptoms but do not cure the disease. Only a doctor can diagnose gastritis. Moreover, it is worth noting that there are several forms of gastritis, which differ in their symptoms and nature of origin. Let's look at each type separately.

    How to choose the right nutrition

    For each form of gastritis, a separate diet is prescribed, which the patient must follow for the entire period of treatment. But it is still possible to highlight individual foods and dishes that are allowed to be eaten with gastritis. Among them:

    • broths from lean meat and fish,
    • dietary meat;
    • steamed casseroles and cutlets;
    • baked and boiled vegetables without seasoning;
    • porridge cooked in water;
    • boiled chicken eggs.

    Some patients are prescribed baby food during an exacerbation. However, we advise you to consult a doctor and not select diets on your own.

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