Compound
The solution for injection contains 42.5 mg/ml hemoderivate (extract) from calf blood as an active substance and water for injection (Aqua pro injectionibus) as an auxiliary component.
One gram of eye gel contains 8.3 g of active substance and auxiliary ingredients: sodium carboxymethyl cellulose (Sodium carboxymethyl cellulose), sorbitol (Sorbitol), water for injection (Aqua pro injectionibus), benzalkonium chloride (Benzalkonii chloridum).
One gram ointment contains 2.07 mg of active substance and a number of auxiliary components: methyl parahydroxybenzoate (E 218; Methyl parahydroxybenzoate), propyl parahydroxybenzoate (E 216; Propyl parahydroxybenzoate), cetyl alcohol (Cetyl spiritus), cholesterol (Cholesterol), white petroleum jelly ( Vaselinum album), water for injection (Aqua pro injectionibus).
One gram of jelly contains 4.15 mg of active substance and a number of auxiliary components: methyl parahydroxybenzoate (E 218; Methyl parahydroxybenzoate), propyl parahydroxybenzoate (E 216; Propyl parahydroxybenzoate), propylene glycol (Propylene glycol), carboxymethyl cellulose sodium salt (Sodium carboxymethyl cellulose), water for injection (Aqua pro injectionibus), calcium lactate pentahydrate (Calcii lactas pentahydrate).
pharmachologic effect
Solcoseryl is a medicine that affects mainly metabolic processes in tissues. They activate tissue metabolic processes , improve trophism and stimulate tissue repair and when exposed to damaging factors.
Solcoseryl in injection form belongs to the pharmacotherapeutic group “ Hemodialysates and hemofiltrates ”, ointment and jelly - to the category of drugs used to treat wounds and ulcers (including poorly healing ones), gel - to the category of drugs used to treat ophthalmological diseases .
Which is better: Metrogyl Denta or Solcoseryl
Both drugs can be used in the treatment of stomatitis. However, it is better to consider them not as drugs of choice, but from the point of view of a combination of two types of gels. The thing is that stomatitis is most often caused by bacterial infection of the tissues of the oral cavity, which causes the appearance of wounds and ulcers. Metrogyl Denta is an antimicrobial drug with a pronounced antibacterial effect. At the same time, everyone who has encountered stomatitis at least once knows how much one wants to speed up the healing process of ulcers that cause severe pain, especially when eating food. Solcoseryl can force tissue to regenerate as quickly as possible, which ensures prompt healing of wounds.
Pharmacodynamics and pharmacokinetics
The main component of Solcoseryl preparations are fractions of the blood of calves with natural low-molecular substances included in their composition, the molecular weight of which does not exceed 5 thousand daltons.
To date, its properties have only been partially studied. In vitro tests, as well as preclinical and clinical studies, have shown that calf blood extract:
- promotes the restoration and/or maintenance of aerobic metabolism and oxidative phosphorylation processes, and also ensures the replenishment of cells that do not receive sufficient nutrition with high-energy phosphates;
- in vitro enhances the utilization of oxygen and activates the transport of glucose into tissues and cells hypoxia and ;
- helps improve repair and regeneration processes in damaged tissues that do not receive sufficient nutrition;
- prevents the development or reduces the severity of secondary degradation and pathological changes in reversibly damaged cells and cellular systems ;
- in in vitro models activates collagen synthesis ;
- has a stimulating effect on the proliferation (reproduction) of cells and their migration (in in vitro models).
Thus, Solcoseryl protects tissues that are in a state of oxygen starvation and nutritional deficiency, and accelerates the processes of their restoration and healing.
Solcoseryl eye gel is a dosage form that was developed specifically for the treatment of lesions with troma of the cornea .
The gel-like consistency of the product ensures its uniform distribution on the cornea , and good adhesive properties allow it to remain on it for a long period of time. The use of eye gel accelerates the restoration of damaged tissues and prevents scarring.
The rate and extent of absorption, distribution, as well as the rate and route of elimination of the active substance from the patient’s body cannot be determined using conventional pharmacokinetic methods, since protein-free calf blood extract has pharmacodynamic effects that are characteristic of molecules with different chemical and physical properties.
In the process of studying the pharmacokinetic characteristics of Solcoseryl solution in animals, it was found that after a bolus injection, the effect of the drug develops within half an hour. The effect lasts for three hours after administration of the solution.
Solcoseryl ointment as a face mask
Cosmetologists claim that the use of Solcoseryl in the early stages of age-related changes allows you to maintain youthful skin. Timely start of use can replace expensive laser rejuvenation in the salon. First of all, Solcoseryl allows you to get rid of wrinkles and prevent their earlier appearance. The ointment is capable of:
- provide adequate nutrition to the facial skin;
- get rid of acne;
- relieve inflammation;
- improve complexion;
- tighten the oval;
- get rid of wrinkles.
The expected effects are possible due to the fact that using a mask allows you to saturate tissues and cells with oxygen and accelerate regeneration. Thanks to the application of the cream, collagen, which is responsible for skin elasticity, begins to be actively produced. The more collagen produced, the fewer wrinkles your skin will have. It is like a support for a heavy skin sheet, preventing its individual areas from falling through, preventing the formation of wrinkles.
Indications for use
Solcoseryl injections: what are they for and what groups of patients are they prescribed for?
Solcoseryl in ampoules is indicated for patients who have been diagnosed with occlusive peripheral artery disease of the third or fourth degree according to the Fontaine classification and who have contraindications or intolerance to other vasoactive drugs .
It is also prescribed to patients with chronic venous insufficiency , which is accompanied by the formation of treatment-resistant trophic ulcers , as well as to patients with disorders of cerebral metabolism .
What is Solcoseryl ointment and jelly for?
The use of ointment and jelly is advisable for the treatment of minor injuries (for example, abrasions or cuts), frostbite, first and second degree burns (thermal or solar), difficult-to-heal wounds (for example, trophic skin disorders of venous etiology or bedsores ).
Indications for use of eye gel
Solcoseryl eye gel is recommended:
- for the treatment of mechanical injuries and erosive damage to the cornea and conjunctiva ;
- to accelerate the healing processes of postoperative scars in the postoperative period (for example, after a cornea transplant , surgery to remove a cloudy lens , surgical treatment of glaucoma , etc.);
- for the treatment of burns of the cornea of various origins (thermal, chemical or radiation);
- for the treatment of ulcerative lesions of the cornea and keratitis of various etiologies ;
- for dystrophic lesions of the cornea of various etiologies, including neuroparalytic keratitis , endothelial-epithelial dystrophy ( bullous keratopathy ), etc.;
- for the treatment of corneal xerophthalmia with lagofatalmos (non-closure of the palpebral fissure);
- to improve the tolerability of contact lenses and reduce the time of adaptation to them.
Indications for use of Solcoseryl dragees
The drug in the form of pills is taken to treat trophic and radiation ulcers , bedsores , gangrene , and chronic venous insufficiency . They are also prescribed to patients with gastric and duodenal ulcers and patients who require skin and/or corneal transplantation .
Solcoseryl (gel), 1 pc., 20 g, gel for external use
Solcoseryl injection solution:
IV
or
IM
.
In the treatment of occlusive diseases of peripheral arteries in stages III–IV according to Fontaine
- IV 20 ml daily. Intravenous drip administration in isotonic sodium chloride solution or 5% glucose solution is possible. The duration of therapy is up to 4 weeks and is determined by the clinical picture of the disease.
In the treatment of chronic venous insufficiency accompanied by trophic disorders (Ulcera cruris)
- IV 10 ml 3 times a week. The duration of therapy is no more than 4 weeks and is determined by the clinical picture of the disease. An important additional measure aimed at preventing peripheral “venous” edema is the application of a pressure bandage using an elastic bandage.
In the presence of local trophic tissue disorders, simultaneous therapy with Solcoseryl jelly and then Solcoseryl ointment is recommended.
In the treatment of ischemic and hemorrhagic strokes in severe and extremely severe forms
as the main course - 10 or 20 ml intravenously, respectively, daily for 10 days. Upon completion of the main course - 2 ml intramuscularly or intravenously for 30 days.
Traumatic brain injury (severe brain contusion)
- IV 1000 mg, daily for 5 days.
If intravenous administration of the drug is not possible, the drug can be administered intramuscularly, usually 2 ml per day undiluted.
When using the undiluted drug intravenously, it must be administered slowly, since it is a hypertonic solution.
Solcoseryl gel, ointment:
topically.
Apply directly to the wound surface after preliminary cleansing of the wound using a disinfectant solution.
Before starting treatment of trophic ulcers, as well as in cases of purulent infection of the wound, preliminary surgical treatment is necessary.
Solcoseryl gel is applied to fresh wounds, wounds with wet discharge, and to ulcers with signs of weeping - a thin layer on a cleaned wound 2-3 times a day. It is recommended to lubricate areas where epithelization has begun with Solcoseryl ointment. The use of Solcoseryl gel continues until pronounced granulation tissue forms on the damaged skin surface and the wound dries out.
Solcoseryl ointment is used primarily for the treatment of dry (non-wetting) wounds.
Solcoseryl ointment is applied in a thin layer to a cleaned wound 1-2 times a day; it can be used under bandages. The course of treatment with Solcoseryl ointment continues until the wound is completely healed, its epithelization and the formation of elastic scar tissue.
For the treatment of severe trophic damage to the skin and soft tissues, the simultaneous use of parenteral forms of Solcoseryl is recommended.
Contraindications
Administration of the solution is contraindicated in patients with known hypersensitivity to calf blood dialysates. The solution is also contraindicated for atopy and for persons allergic to milk .
Since the ointment, jelly and solution contain derivatives of parahydroxybenzoic acid , which are used as preservatives, as well as trace concentrations of benzoic acid in free form, it is not used in the presence of allergic reactions to the above substances.
With caution, ointment and jelly are prescribed to persons with a predisposition to allergic reactions .
A contraindication to the use of eye gel is hypersensitivity to its components. Since the eye gel can cause temporary visual impairment, you should not drive a car or operate potentially dangerous machinery for half an hour after its use.
Contraindications and side effects –
The only contraindication for use is the presence of hypersensitivity to any of the components of the drug. The ointment has no contraindications depending on age, as well as contraindications for use during pregnancy and lactation.
However, if you are predisposed to allergic reactions (especially to cosmetics or oral hygiene products), you should use this drug with caution. An allergic reaction to Solcoseryl ointment usually develops as urticaria or dermatitis. If an allergy occurs, you should stop using the drug. Please note that when applying the ointment, a short-term burning sensation may appear (this is absolutely normal), but if the burning does not go away, then the ointment should be washed off and further use of the drug should be discontinued.
Special instructions -
- Solcoseryl ointment should not be applied to contaminated, infected wounds, because the drug does not contain antimicrobial components. Also, the ointment is not suitable for treating wounds with wet discharge (here you need a form of Solcoseryl in the form of a gel).
- If you experience pain, swelling, redness, a fistula with discharge near the site where the ointment was applied, or an increase in body temperature, you should immediately consult your doctor, because these are the first symptoms of purulent inflammation.
- If, while using the drug, your wound does not heal (about 2 weeks), you should immediately consult a doctor, because this may indicate the presence of a benign or malignant tumor. We hope that our article on the topic: What is Solcoseryl ointment used for, treatment regimens - turned out to be useful to you!
Sources:
1. Dental education of the author of the article, 2. Additional professional education in the field of cosmetology, 3. Personal experience as a maxillofacial surgeon, 4. “Outpatient surgical dentistry” (Bezrukov V.), 5. https://solcolife.ru/.
Side effects
Administration of Solcoseryl IV or IM in very rare cases (their frequency does not exceed 0.1%) provokes the development of allergic or anaphylactic reactions , which are most likely caused by class E immunoglobulins .
If body temperature rises, urticaria , swelling and hyperemia at the site of drug administration, the use of Solcoseryl is stopped, and symptomatic treatment will be prescribed to eliminate the symptoms that appear.
Since the solution contains potassium, its administration may cause pain at the injection site.
When using Solcoseryl cream, a short-term burning sensation may be felt at the site of application. Discontinuation of the drug is required only in cases where the unpleasant sensation does not disappear for a long period of time.
In isolated cases, the use of jelly and ointment can cause the development of allergic reactions . If allergy symptoms , the use of these products should be discontinued.
Toxicological studies of Solcoseryl eye gel have shown the high safety of this drug when used for its intended purpose in accordance with the instructions.
After instillation of the product, a short-term burning sensation and mild irritation may be observed, which are not reasons for stopping treatment. Repeated instillation in rare cases provokes the development of allergic reactions (a similar effect is also observed during treatment with other ophthalmic drugs for topical use).
Solcoseryl, 1 pc., 20 g, ointment for external use
Solcoseryl injection solution:
IV
or
IM
.
In the treatment of occlusive diseases of peripheral arteries in stages III–IV according to Fontaine
- IV 20 ml daily. Intravenous drip administration in isotonic sodium chloride solution or 5% glucose solution is possible. The duration of therapy is up to 4 weeks and is determined by the clinical picture of the disease.
In the treatment of chronic venous insufficiency accompanied by trophic disorders (Ulcera cruris)
- IV 10 ml 3 times a week. The duration of therapy is no more than 4 weeks and is determined by the clinical picture of the disease. An important additional measure aimed at preventing peripheral “venous” edema is the application of a pressure bandage using an elastic bandage.
In the presence of local trophic tissue disorders, simultaneous therapy with Solcoseryl jelly and then Solcoseryl ointment is recommended.
In the treatment of ischemic and hemorrhagic strokes in severe and extremely severe forms
as the main course - 10 or 20 ml intravenously, respectively, daily for 10 days. Upon completion of the main course - 2 ml intramuscularly or intravenously for 30 days.
Traumatic brain injury (severe brain contusion)
- IV 1000 mg, daily for 5 days.
If intravenous administration of the drug is not possible, the drug can be administered intramuscularly, usually 2 ml per day undiluted.
When using the undiluted drug intravenously, it must be administered slowly, since it is a hypertonic solution.
Solcoseryl gel, ointment:
topically.
Apply directly to the wound surface after preliminary cleansing of the wound using a disinfectant solution.
Before starting treatment of trophic ulcers, as well as in cases of purulent infection of the wound, preliminary surgical treatment is necessary.
Solcoseryl gel is applied to fresh wounds, wounds with wet discharge, and to ulcers with signs of weeping - a thin layer on a cleaned wound 2-3 times a day. It is recommended to lubricate areas where epithelization has begun with Solcoseryl ointment. The use of Solcoseryl gel continues until pronounced granulation tissue forms on the damaged skin surface and the wound dries out.
Solcoseryl ointment is used primarily for the treatment of dry (non-wetting) wounds.
Solcoseryl ointment is applied in a thin layer to a cleaned wound 1-2 times a day; it can be used under bandages. The course of treatment with Solcoseryl ointment continues until the wound is completely healed, its epithelization and the formation of elastic scar tissue.
For the treatment of severe trophic damage to the skin and soft tissues, the simultaneous use of parenteral forms of Solcoseryl is recommended.
Instructions for use of Solcoseryl (Method and dosage)
Solution for injection: instructions for use
In cases where the patient's condition allows, the drug is recommended to be used in the form of an injection solution diluted at least 50:50 with saline or glucose solution .
Solcoseryl in ampoules is intended for slow administration in the form of intravenous injections or infusions. If intravenous administration is not possible, the drug can be injected into the muscle.
Since the drug in its pure form is a hypertonic solution, it should be administered slowly.
For intravenous infusion, the drug should be pre-diluted with 0.25 l of 0.9% NaCl solution or 5% glucose solution . Solcoseryl solution is administered intravenously by drip. The rate of administration depends on the hemodynamic status of the patient.
Patients with occlusive disease of peripheral arteries of the third or fourth degree according to the Fontaine classification are shown daily injection into a vein of 0.85 g (or 20 ml of undiluted solution) Solcoseryl.
The duration of use is usually up to four weeks and depends on the clinical situation.
Patients with chronic venous insufficiency , which is accompanied by the formation of treatment-resistant trophic ulcers , are indicated for intravenous administration of 0.425 g (or 10 ml of undiluted solution) Solcoseryl three times a week.
The duration of the course of treatment should not exceed four weeks (it is determined depending on the nature of the disease).
To prevent the appearance of peripheral “venous” edema , therapy is supplemented by applying a pressure bandage using an elastic bandage. If the patient has skin trophic disorders, treatment is carried out by combining injections or infusions of Solcoseryl solution with the use of jelly, and then ointment.
Patients who have suffered ischemic or hemorrhagic stroke are prescribed daily intravenous administration of 0.425 or 0.85 g of Solcoseryl (10 or 20 ml of undiluted solution) as the main course. The duration of the main course is 10 days.
Further treatment involves daily administration of 85 mg (or 2 ml of undiluted solution) Solcoseryl for one month.
In severe forms of brain contusions, daily injection of 1000 mg of Solcoseryl into a vein (corresponding to 23-24 ml of undiluted solution) is prescribed for 5 days.
The drug is administered intramuscularly undiluted at a dose of 2 ml/day.
Solcoseryl jelly and ointment: instructions for use
Cream and ointment are intended for application directly to the wound surface. Before using these dosage forms, the wound is first cleaned using a disinfectant solution.
Patients with trophic ulcers , as well as in cases of purulent infection of wounds , require preliminary surgical treatment before starting treatment.
When using jelly and ointment for frostbite , as well as for the treatment of ulcers and skin injuries , it is important to remember that only sterile dressings should be used to treat damaged areas.
The gel is intended for application to fresh (including wet) wounds and weeping ulcers . The product is applied in a thin layer to a previously cleaned wound surface two or three times a day.
To treat areas where epithelization has begun, the use of ointment is indicated. The use of jelly is advisable until pronounced granulation tissue begins to form on the damaged surface of the skin and the wound begins to dry out.
The ointment is used primarily for the treatment of dry (without weeping) wounds . The product is applied in a thin layer to a previously cleaned wound surface once or twice a day. If necessary, cover the treated surface with a bandage.
The course of treatment with the drug in this dosage form continues until the wound heals and is completely healed with elastic tissue.
For patients with severe trophic damage to the skin and soft tissues, it is recommended to combine jelly and ointment with the injection form of Solcoseryl.
Experience with the use of jelly and ointment for children is limited.
The drug does not have such release forms as suppositories. However, in the complex therapy of chronic colitis (inflammation of the colon), microenemas with Solcoseryl jelly are often prescribed.
Before use, the jelly contained in the tube (all 20 g) is added to 30 ml of warm water and after the enema procedure, which is carried out to cleanse the intestines , it is administered daily for 10 days.
Solcoseryl eye gel: instructions for use
Unless otherwise instructed by the attending physician, the eye gel is instilled into the conjunctival cavity , one drop three or four times a day. It is recommended to use the product daily until complete recovery.
In particularly difficult cases, eye ointment can be used one drop per hour. If the patient is simultaneously prescribed eye drops and Solcoseryl eye gel, the gel should be applied approximately half an hour after the drops.
During the period of adaptation to contact lenses, the drug is instilled into the conjunctival cavity immediately before installing the lenses and immediately after removing them.
Dragee Solcoseryl: instructions for use
The instructions recommend taking 100 mg tablets three times a day.
Solcoseryl injections: what for
Any surgical intervention is accompanied by a violation of the integrity of the skin and tissues. If the operation involves the removal of some fragment of an internal organ, the body will require a long rehabilitation period, during which the body will be fully or partially restored. Solcoseryl in ampoules can be instantly delivered to tissues, shortening the recovery period. Injections allow you to mobilize all the internal forces of the body to heal wounds, cuts and sutures not only on the outside, but on the internal organs that remain after operations.
Special cases include the prescription of intravenous or intramuscular administration to patients after ophthalmological operations. Solcoseryl ensures active blood circulation, which accelerates the process of adaptation of the organ of vision in the postoperative period, and also reduces the risk of complications.
special instructions
Studies regarding the safety of using Solcoseryl solution for the treatment of children have not been conducted, therefore the drug is not recommended for the treatment of children under the age of 18 years.
Experience in treating children with the use of eye gel and topical dosage forms of the drug is also limited.
Solcoseryl in ampoules should be administered separately from other drugs (it is especially incompatible with phytoextracts). The exceptions are isotonic 0.9% NaCl solution and 5% glucose solution . It is also not recommended to dilute the product in potassium-containing solutions for infusion.
Eye gels are characterized by the ability to stick to contact lenses, so it is recommended to stop wearing lenses during treatment with the drug.
If allergic reactions associated with the use of the drug, you should immediately report them to your doctor. If the drug is used to treat an infectious disease of the cornea , therapy is supplemented with the prescription of appropriate antimicrobial agents .
Avoid contact of the gel with soft contact lenses as it may discolor them.
If necessary, treatment with Solcoseryl can be supplemented with antibacterial , vasodilating and other drugs.
Solcoseryl in cosmetology: for the face, hands, rough elbows and heels, for the skin around the eyes
In medicine, Solcoseryl preparations are used to accelerate the healing of damaged skin; in home cosmetology, they are used as a remedy for acne, stretch marks, and wrinkles. They are used to soften the skin, increase its turgor, improve complexion and eliminate acne .
In cosmetology, the ointment can be used as a stand-alone product (it is applied pointwise to problem areas, in the form of a mask once a week before bedtime and two to three times a week on the skin around the eyes), or in combination with other products, in particular with the drug Dimexide . Let's look at how to use these medications together.
For the face, Dimexide and Solcoseryl are used as follows: on the face, neck and décolleté, previously cleaned with peeling agents (you can also do alkaline peeling using tar soap, salt and soda), apply a solution of Dimexide with water, prepared in a ratio of 1:10 (enough dilute 5 ml (teaspoon) of Dimexide in 50 ml of water); Before the product has time to be absorbed, Solcoseryl ointment is applied to it in a thick layer.
If the gel is used in cosmetology, then the mask should be periodically sprayed with thermal water (you can also use regular water through a spray bottle). The mask is left on the face for about half an hour to an hour, then washed off and a light hypoallergenic cream is applied to the skin.
According to women who have tried this mask recipe on themselves, Solcoseryl ointment is more comfortable for the face than gel (after application, you don’t have to wash it off, just remove the residue with a napkin). In addition, it is not recommended to use a gel mask more than once a month.
Used as a remedy for wrinkles around the eyes, Solcoseryl ointment has proven itself to be a very effective remedy. Applying it like a regular cream, within a week you can see that the number of wrinkles and wrinkles has decreased, the skin has tightened and smoothed, and its color has become fresher and healthier.
Dimexide and Solcoseryl are no less effective against wrinkles, and perhaps even more effective. This is due to the ability of Dimexide to enhance the penetration of the active substance of drugs deep into the tissue. After using these products in combination, skin irregularities and imperfections disappear, and the effect of the mask is comparable to the effect of Botox .
The gel and ointment can also be used to soften rough skin on the elbows and heels. It is best to apply them to problem areas before bed.
Analogues of Solcoseryl
Level 4 ATX code matches:
Badyaga Forte
Badyaga
Rogaine
Capsiol
Vulnuzan
Skin cap
Petrolatum
Generolon
Alerana
Apilak
Tsinocap
Silocast
Analogs of Solcoseryl: Aekol , Acerbin , Bepanten , Shostakovsky balm , Vundehil , Depantol , Contractubex , Pantekrem , Pantexol Yadran , Panthenol , Pantestin , Hepiderm Plus , Echinatsin Madaus .
Reviews of Solcoseryl
Almost all reviews left on the forums about injections, eye gel, jelly and Solcoseryl ointment are positive. Rare negative reviews are due largely to the fact that the drug provoked allergic reactions associated with intolerance to its active component.
Reviews of Solcoseryl gel and the drug in the form of an ointment allow us to conclude that these drugs effectively cope not only with minor scratches and minor burns, but also help cure difficult-to-heal wounds and ulcers .
The average rating of a drug on sites where people share their impressions of certain drugs is 4.8 on a 5-point scale.
The effectiveness of the ointment in cosmetology is also highly appreciated. Reviews of Solcoseryl ointment for the face indicate that this is truly an indispensable product for those who want to quickly get rid of wrinkles, acne, and simply improve the color and tone of the skin.
Gel is no less effective against wrinkles, but cosmetologists believe that it should not be used as part of masks too often (optimally - once a month). The ointment can be used as a regular cream.
The effectiveness of Solcoseryl against wrinkles increases when combined with Dimexide, which is due to the latter’s ability to improve the penetration of the active substance deeper into the skin.
Solcoseryl anti-wrinkle ointment: reviews
Sometimes patients use Solcoseryl facial ointment for cosmetic purposes to get rid of wrinkles.
The logic here is clear - since the drug increases the proliferation and activity of fibroblasts and leads to an increase in collagen production in damaged skin tissues (in wounds), then its regular use should probably lead to an increase in collagen production in healthy, undamaged skin. However, when using Solcoseryl ointment for wrinkles, reviews from cosmetologists indicate the absence of an anti-aging effect. The fact is that the drug affects the production of collagen and the proliferation of fibroblasts exclusively where the skin tissue has been damaged. As soon as the process of tissue restoration ends (and the young granulation tissue that has arisen at the site of damage turns into mature connective tissue), the effect of the drug stops.
However, long-term use of Solcoseryl ointment for the face (given the content of a fatty substance in it) can moisturize the skin, making it a little more elastic. But this does not occur due to an increase in collagen content, but due to a fatty film on the surface of the skin, which prevents the evaporation of moisture and therefore makes the skin a little more hydrated. At the same time, in patients with acne, the ointment can also cause an exacerbation of acne and pimples (due to the Vaseline content).
To stimulate collagen production in aging skin, the following 2 types of products are most effective (for arguments and clinical studies, see the links below) –
- products with retinoids,
- fractional lasers.
Solcoseryl price, where to buy
How much does Solcoseryl cost in Ukraine?
The average price of Solcoseryl in ampoules in Ukrainian pharmacies is from 265 to 515 UAH (depending on the volume of ampoules and their number in the package). The price of Solcoseryl ointment in Ukraine is 57-60 UAH. You can buy jelly for an average of 52 UAH. Eye cream costs on average from 60 to 74 UAH.
Cost of the drug in Russia
The price for Solcoseryl injections in Russian pharmacies varies from 400 to 1300 rubles (depending on the volume of ampoules and their number in the package). The price of Solcoseryl gel (which can be used as an anti-wrinkle gel) is 180-200 rubles. The price of the eye gel is 290-325 rubles. Pharmacies provide information on the price of tablets upon request.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
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