Lespenefril, lespefril, lespeflan for cats and dogs

Description and characteristics

The medicine is made on the basis of plant materials and is used as a symptomatic medicine against chronic kidney failure (CRF). The main component of the solution is an extract of lespedeza bicolor shoots. The composition also contains ethyl alcohol (solvent) and anise oil.

The drug has a diuretic effect, but does not flush potassium and magnesium from the body.

Lespedeza is a natural regulator of metabolic processes in the body, affecting the functioning of all systems. The medicine is included in complex therapy and is used separately.

When treating the genitourinary system and kidneys, the solution alleviates the course of the disease and shortens the period of exacerbation of chronic renal failure. As part of complex therapy, Lespefril has the following effects:

• restoration of metabolism;
• maintaining and restoring immunity;
• regulation of water-salt metabolism in the body;
• excretion of nitrogenous wastes through urine;
• increasing the rate of sodium excretion.

The medication is available in the form of a solution for internal use. The standard packaging volume is 100 milliliters. The average cost of a bottle is 150-200 milliliters, dispensed without a doctor’s prescription. Due to the characteristics of the composition and mechanism of action, information on pharmacokinetics and pharmacodynamics is insufficient.

Storage and sales conditions

The drug is available exclusively in liquid form. Manufacturer: VIFITECH (Russia). When purchasing, you do not need a doctor's prescription, but it is not recommended to purchase the medication without a prescription due to the list of contraindications.

The medicine must be stored in a dark place, protected from children and animals, at a temperature of 15 to 25 degrees. The shelf life of unopened packaging is 3 years. After opening and consumption, the shelf life is reduced to a month.

Differences between Lespefril and Lespeflan

Lespeflan is a herbal medicine in the form of a solution. Sold through pharmacy chains at an average cost of 200-240 rubles without a doctor’s prescription. Manufacturers of the drug: DALKHIMFARM (Russia), PHARMACENTR VILAR (Russia). The main component of the medicine is also a liquid extract of lespedeza bicolor shoots. The composition contains ethyl alcohol and anise oil.

Differences from Lespefril can be studied according to the instructions. The manufacturer of Lespeflan indicates that the list of side effects may include heartbeat disturbances, tachycardia, and slowed psychomotor reactions. The solution rarely causes allergic reactions. The difference is also in price. The average cost of Lespeflan is 30-40 rubles higher in Russian pharmacy chains. The dosages of the medication are the same; the instructions recommend taking the medication before meals once a day.

Analogues and substitutes of the drug

A complex of mild diuretic, anti-inflammatory and analgesic effects can be provided by a lot of herbal and chemical-based medicines. Substitutes with a similar composition and mechanism of action are produced in liquid form.

Analogs are selected if Lespefril is insufficiently effective or if there is increased sensitivity to the manufacturing components.

Indications and features of use

The main indication for use of the drug is chronic renal failure. With this disease, the drug helps relieve inflammation and improve fluid excretion. Lespefril also helps as part of complex therapy for the following lesions and conditions of the body:

• pyelonephritis;

• urolithiasis disease;
• kidney stone disease;
• glomerulonephritis.

The main purpose of the medicine is auxiliary. The medication improves the general condition of patients, helps improve well-being, and eliminates unwanted symptoms. Lespefril is effective against kidney disease in which renal failure is a symptom or complication.

Before use, the medicine must be diluted in a small amount of clean water.

The drug is used up to four times a day. The size of one dosage for an adult is from 5 to 15 milliliters (from a teaspoon to a tablespoon), depending on the indications, the severity of the lesion and the individual characteristics of the patient. The duration of the therapeutic course is also determined individually.

Typically it lasts from three to four weeks. The course can be repeated with a break of two to three weeks. Meal regimen is not important since absorption data are not available.

Contraindications for use

Despite its relatively safe composition, the medication has some contraindications, which are important to consider when prescribing treatment. Absolute restrictions include:

• children's age (up to 18 years);
• alcohol dependence (the drug is incompatible with alcohol due to an increase in the level of toxicity in the body and danger to the liver);

• epilepsy;
• pregnancy, breastfeeding;
• traumatic brain injuries;
• liver damage, dysfunction of the hepatic system against the background of progression of various pathologies of the organ;
• hypersensitivity to the main component and other substances in the composition of the drug;
• various types of brain diseases.

The drug should not be taken together with disulfiram, non-selective monoamine oxidase inhibitors. Complex therapy with the use of sulfonamide and metformin is not recommended. The effects of sedative medications can be unpredictable, so treatment using them is also excluded. Also, when used together, it is important to take into account the presence of ethyl alcohol in the composition, which can increase toxicity and side effects.

Particular caution should be exercised in patients suffering from insulin-dependent diabetes mellitus, since Lespefril is not compatible with insulin medications.

It is not recommended to use Lespefril in cases of severe hyponatremia. But the condition can be compensated for with sodium medications.

During the treatment period, care must be taken when driving vehicles and machinery. It is recommended to avoid activities that require increased concentration and quick reactions.

What is better than Lespefril and Lespenefril?

Lespenefril and Lesprefril differ insignificantly in composition. Lespenefril is based on lespedeza capitate powder, ethyl alcohol and anise essence (Lesprefril contains anise oil). In terms of use, Lespenefril is better because it is sold in a solution for internal use and injection.

This allows you to expand the range of applications, but increase the list of contraindications and side effects. The average cost of a package of medicine is 120-130 rubles. Manufacturer: UCB HealthCare (France).

Negative effects

Lespefril is a relatively safe herbal medicine that rarely causes side effects. In some cases, allergic reactions may occur in the form of urticaria, skin rash and redness, itching, and swelling. The drug does not wash out potassium and magnesium, but with systematic use there is a risk of hyponatremia. In such situations, medications, multivitamins and foods containing sodium help compensate for the loss of microelements. In case of overdose, the likelihood of allergies and hyponatremia increases.

Taking Lespefril together with alcohol can enhance the effect of the latter. Ethyl alcohol is also contained in the solution. The component can also enhance the effect of other medications, which is important to consider when using other medications, including sedatives. If it is necessary to include other medications in a complex treatment, it is important to consult a doctor to prevent the development of undesirable effects.

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