Rumalon in injections - indications for use

Description of the drug and action

Rumalon belongs to the group of drugs that improve metabolic processes in cartilage tissue. The drug is produced in the form of a solution, packaged in 1 ml ampoules. Ampoules in a package of 10 pieces cost 1,150 rubles, in a package of 25 — 2,150 rubles. The product is a prescription product and is produced in Romania.

The main effect is due to the work of the active glycosaminoglycan-peptide complex, which is part of Rumalon.

This substance is obtained from the trachea and bone marrow of cattle, it is isolated from the extract of these parts. The solution is transparent, has a yellowish or brownish tint, and has a characteristic odor of metacresol. The latter is present in the solution as a preservative. Each ml of the drug contains 2.5 mg of the main substance.

The medicine is of natural (animal) origin. The peptide complex belongs to the biogenic stimulants, provides a powerful chondroprotective effect - protects joint cartilage from destruction and damage. The drug has the following actions:

• reduces the speed and force of action of enzymes that disrupt the strength of joint tissues;
• inhibits catabolic processes;
• normalizes the metabolism of hyaline tissue;
• helps accelerate the production of collagen, mucopolysaccharides, glycosaminoglycans;
• stimulates cell regeneration.

Thus, the drug accelerates the restoration of damaged joint tissues using the body’s own forces and itself serves as a “building material”. It improves the quality and increases the quantity of lubricant - intra-articular fluid, and optimizes the nutrition of the joint.

Indications of the drug

The main indication for the use of Rumalon is the presence of any stage of osteoarthritis of the joints. With this disease, thinning of the cartilage plate, disruption of the integrity of the cartilage and changes in its surface are observed. This degenerative pathology most often begins in the following joints:

• knee;
• ankle;
• elbows.

The drug is also indicated for other forms of joint arthrosis. Rumalon in injections helps against arthrosis of the interdigital joints, and against coxarthrosis - damage to the heads of the pelvic bones. Other indications include the following pathologies:

• dystrophy of the joints of the toes and feet;
• inflammatory process in the bags located around the joints (bursitis);
• osteochondrosis - decreased height of intervertebral cartilage;
• meniscopathy - damage, destruction of the menisci of the knees;
• chondromalacia - necrosis of cartilage, which most often occurs after injuries to the kneecaps;
• spondylosis - depletion of the cartilage of the intervertebral joints, including in combination with arthrosis (spondyloarthrosis).

The medicine can also be given to prevent the progression of these diseases and to prevent their development in a patient with a large number of risk factors. Also, the preventive use of Rumalon is indicated for those with a genetic predisposition to such pathologies.

Contraindications, indications for treatment

The instructions recommend the use of Rumalon for degenerative lesions of the joints:

• for arthrosis, spondylosis, coxarthrosis;
• meniscopathies – pathologies of cartilage in the knee joints, accompanied by functional disorders and pain;
• spondyloarthrosis, gonarthrosis;
• chondromalacia – necrosis of cartilage cells.

The medicine is contraindicated in patients:

• with individual intolerance to the component composition;
• rheumatoid arthritis, thrombophlebitis;
• tendency to spontaneous bleeding.

Rumalon is not prescribed to pregnant and lactating women and minor patients. During lactation, the medication can be used provided that the newborn is transferred to artificial nutrition.

Particular caution and supervision by the attending physician is needed during treatment with the drug in patients with blood clotting disorders, diabetes mellitus, renal, and hepatic pathologies. The same requirements apply to women planning pregnancy and overweight or obese patients.

Side effects

The instructions describe how many and what negative actions may occur. The drug is usually well tolerated, but if abused, used for too long, or in people prone to sensitization, a number of side effects may occur. Injections should be given with caution to those who often undergo allergic reactions.

The use of Rumalon can cause rash, itchy skin, flushing, hyperthermia, and even anaphylactic shock and Quincke's edema.

If any allergy develops, treatment should be stopped immediately before the existing phenomena begin to develop and reach a severe form.

Sometimes allergies occur when the dosage is used incorrectly or when the dosage is exceeded. The following side effects may also worsen the patient's condition:

• dizziness, headaches;
• feeling of weakness;
• decline in performance;
• migraine;
• throbbing pain;
• vascular spasms.

From the gastrointestinal tract, vomiting and nausea are sometimes observed, pain in the abdomen, stomach, and symptoms of dyspepsia, including bloating, gas formation, and diarrhea may appear. If you inject increased doses of the drug, joint pain is recorded, which later goes away.

Local reactions often include pain at the injection site, redness, swelling or a slight bruise. Local phenomena usually do not require discontinuation of the drug. Also considered normal is moderate pain in the limbs, which appears during therapy and goes away a few hours after the injection.

Adverse reactions

Therapeutic procedures can provoke non-standard responses of the body, manifested by:

• dizziness, cephalgia, erythema;
• nettle fever, eczema, maculopapular rash with itching or swelling;
• dyspeptic disorders, nausea with vomiting;
• allergies, anaphylaxis, Quincke's edema;
• painful sensations in the joints - the disorder does not require discontinuation of the medication and goes away spontaneously;
• local bleeding - in the area of ​​drug administration.

The occurrence of side effects during therapy with Rumalon requires additional consultation with a doctor. The patient must describe in detail the deviations that have arisen, and the specialist must select a more suitable drug.

Contraindications for Rumalon

Prohibitions on treatment include intolerance to components, hypersensitivity in response to the administration of the drug. Rumalon is prohibited for use in children (due to insufficient data); it is indicated only for adults over 18 years of age. Contraindications are pregnancy and lactation.

Rumalon should not be given if the patient is diagnosed with rheumatoid arthritis, an autoimmune disease of the joints: the prohibition is due to the possibility of increasing the immune response, which will harm the body.

Also, injections are prohibited for women of reproductive age who do not use reliable methods of contraception. This is associated with the risk of developing pregnancy and continuing therapy, whereas during gestation it is prohibited. The medicine should be administered with caution to those patients who have already had allergic or hypersensitivity reactions to similar drugs or other drugs of animal origin.

How to give Rumalon injections correctly?

The drug is given intramuscularly, injected deeply, gradually. Therapy should be carried out according to a special scheme:

• on the first day, 0.3 ml is administered;
• on the second day put 0.5 ml;
• then they begin to administer the medicine three times a week, 1 ml;
• similarly treated for up to 5-6 weeks.

The treatment regimen is always the same, regardless of the initial or repeated course. With proven clinical effectiveness, courses can be repeated, taking a break of several months. Repeated courses must have a clear recommendation from a doctor with the necessary preliminary examinations. The doctor can extend the therapeutic course to 8 weeks.

Special conditions

There are a number of recommendations for treatment and instructions on the body’s reactions to the use of the drug:

• Rumalon does not affect attention or memory, it can be used without fear when operating vehicles or machinery;
• the solution is intended only for intramuscular injections;
• the drug cannot be injected into the upper layers of fatty tissue; deep administration is practiced;
• a gradual increase in dosage is necessary to minimize the risk of severe allergic reactions;
• if a rash or spots appear on the skin after the first dose of the medicine, further therapy should be abandoned;
• the effect in the form of pain reduction and improvement in the functional state of joints is usually achieved 14 days after the start of therapy, which does not mean the possibility of an unauthorized reduction in the course;
• Rumalon is compatible with any type of physiotherapeutic treatment;
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• During therapy, it is better to completely avoid drinking alcoholic beverages, since alcohol reduces the absorption of the active substance.

There were no cases of overdose. However, with increasing or prolonging the dose, the risk of side effects or hypersensitivity reactions increases, so you must follow the prescribed Rumalon dosage.

Instructions from the manufacturer and interaction features

The instructions indicate the following nuances:

• therapeutic procedures with Rumalon are stopped when signs of an allergic reaction appear;
• the medication is prohibited for use by minors, pregnant and lactating women;
• Before using the medicine, a diagnostic examination and confirmation of the presumptive diagnosis is necessary.

Improvement in joint mobility, suppression of pain and other therapeutic effects are recorded 14-21 days from the start of treatment. The results obtained last for several months after completion of the procedures.

Rumalon improves the effect of individual drugs during joint therapy, the list includes:

• indirect anticoagulants;
• antiplatelet agents;
• fibrinolytics.

The combination with them requires regular checking of blood clotting speed. Combining Rumalon with NSAIDs allows you to reduce the dosage of the latter medications.

Analogs and other data

There are no analogs with exact structure in pharmacies; Rumalon is a unique drug that does not even have generics. According to indications, there are a number of other medications in the form of injections, but replacement is allowed only with the approval of a doctor:

Rumalon is often used in conjunction with corticosteroids and NSAIDs. Both of these groups of drugs are indicated for severe pain, which often accompanies arthrosis and other inflammatory, degenerative diseases of the joints and spine. When taking Rumalon with anticoagulants, fibrinolytics, or antiplatelet agents, their effect may be enhanced, which must be taken into account when selecting an adequate dose. To avoid unpleasant consequences with this combination of drugs, you need to regularly take blood clotting tests.

Analogs

The occurrence of intolerance to the drug or side effects requires its replacement. The list of popular analogues is presented:

• Alflutop;
• Arthroi;
• Bishofite;
• Gialganom Phidias;
• Glucosamine-Chondroitin;
• Incenoy;
• KONDROnova;
• Movex Comfort;
• Piaskledin 300;
• Traumemel S;
• Chondroitin Complex;
• The goal of T.

The product has no complete structural analogues.