Dimexide: how to take the drug

Composition of Dimexide

The concentrate for preparing Dimexide solution contains at least 99% dimethyl sulfoxide (DMSO) undiluted.
Dimexide gel contains DMSO at a concentration of 0.25 mg/g or 0.5 mg/g, as well as nipagin, nipazole, sodium carmellose, and purified water.

Dimexide ointment is prepared on the basis of polyethylene oxide 1500 gel (an emulsifier is added to it to give the preparation the necessary consistency) or on the basis of mink oil. The concentration of the active substance is from 30 to 70%.

DMSO is also included in some gels and ointments ( Triacort , Dolobene , Chondroxide , Capsicam , Remisid , Ketorol) , but in them it acts as a penetrator and is not an active substance.

Contains DMSO and Propolis-D . In addition to this substance, the medicine contains propolis extract 20% and cocoa butter.

Pharmacodynamics and pharmacokinetics

Dimexide - what is it?

To the question “What is Dimexide?” Wikipedia answers that this is an external drug that is used primarily to relieve pain and inflammation in diseases of the musculoskeletal system (MSD), as well as to enhance the penetration of a number of other drugs into tissues.

Pharmacodynamics

The mechanism of action of DMSO is associated with the ability of this substance to inactivate hydroxyl radicals and improve the course of metabolic processes in the site of inflammation.

The drug has a local analgesic and anesthetic effect . Shows moderate fibrinolytic and antiseptic activity.

DMSO helps normalize the processes of fibrin formation, improves microcirculation in tissues, inhibits erythrocyte and neutrophil , increases the activity and intensity of phagocytosis , and reduces the content of CEC.

When applied topically, it quickly and well passes through biological membranes (mucous membranes, skin, bacterial cell walls), increasing their permeability to other drugs.

These properties of DMSO allow it to be used as a transporter of other drugs through mucous membranes and skin.

Pharmakinetics

When applied to mucous membranes or skin, it is absorbed quickly and almost completely.

Bioavailability - 60-70%. Moreover, the penetration depth and bioavailability of DMSO are directly proportional to its concentration.

After application to the skin, the drug is detected in the blood serum within ten minutes. Concentrations reach peak values ​​after four to eight hours.

Penetrates well into tissue cells of all organs. The exception is cells of nails, hair, and tooth enamel.

In the body, DMSO is oxidized to methylsulfonylmethane and then reduced to dimethyl sulfide.

The active substance and its metabolic products are excreted in feces and urine. In addition, DMSO can be excreted through the lungs and skin, which is accompanied by the appearance of a specific garlic odor.

Even with long-term use of Dimexide, DMSO and its metabolites do not accumulate in the body.

Instructions for use

Registration number

No. LP-000501 dated 03/01/2011

Trade name of the drug

Dimexide

International nonproprietary name

Dimethyl sulfoxide

Dosage form

Gel for external use

Compound

Description

Colorless or yellowish-tinged transparent gel with a weak specific odor.

Pharmacotherapeutic group

Anti-inflammatory agent for external use.

ATX code

[MO2AHO3]

Pharmacological properties

An anti-inflammatory agent with local analgesic and anti-inflammatory effects. Has a moderate antiseptic and fibrinolytic effect.

Pharmacodynamics

Dimethyl sulfoxide inhibits inflammatory tissue infiltration. In addition, dimethyl sulfoxide helps normalize fibrin formation processes. Dimethyl sulfoxide increases microcirculation in tissues, inhibiting erythrocyte aggregation, increases the activity of phagocytes, suppresses neutrophil chemotaxis and reduces the content of circulating immune complexes. Penetrates through the skin, mucous membranes, bacterial cell walls (increases their sensitivity to antibiotics) and other biological membranes, increases their permeability to drugs. The drug is low toxic.

Pharmacokinetics

When applying the drug, dimethyl sulfoxide is detected in the blood serum after 8-15 minutes, with the maximum content observed after 2-8 hours. As a rule, after 30-36 hours, dimethyl sulfoxide is no longer detected in the blood serum. Dimethyl sulfoxide does not accumulate. When applied topically, dimethyl sulfoxide penetrates the joint cavity and binds to proteins in the blood and tissues. Dimethyl sulfoxide is excreted from the body through the kidneys unchanged and in the form of oxidation products - dimethyl sulfone and dimethyl sulfate; and also in the form of a reduced product (dimethyl sulfide) is released in exhaled air.

Indications for use

Used to relieve pain in the complex treatment of rheumatoid arthritis, ankylosing spondylitis, deforming osteoarthritis, arthropathy, radiculitis, trigeminal neuralgia, etc., for the treatment of bruises, ligament damage, traumatic infiltrates, and in the treatment of erythema nodosum.

Contraindications

Hypersensitivity to Dimexide or other components of the drug, pregnancy, lactation, severe liver and kidney damage, angina pectoris, myocardial infarction, severe atherosclerosis, various types of stroke, glaucoma, cataracts, coma, children under 12 years of age. Carefully

Due to the fact that Dimexide can enhance not only the activity, but also the toxicity of some drugs, caution should be exercised when prescribing it simultaneously with other drugs.

Directions for use and doses

Externally. For adults and children over 12 years of age, the drug is applied in a thin layer to the affected area 1-2 times a day. Duration of treatment is 10-14 days. Repeated courses can be carried out no less than 10 days later.

Side effect

During the use of the drug, contact dermatitis, a garlicky odor of exhaled air, increased skin pigmentation, allergic reactions, erythematous rashes, dry skin, and a slight burning sensation may be observed. Some patients do not perceive the smell of the drug well (nausea, vomiting); in isolated cases, bronchospasm is possible.

If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Overdose

Symptoms: increased dose-dependent side effects. In these cases, the drug should be discontinued, the damaged area should be washed, and the drug should be removed.

Interaction

Compatible with heparin, antibacterial drugs, non-steroidal anti-inflammatory drugs (NSAIDs). Increases the sensitivity of microorganisms to aminoglycoside and beta-lactam antibiotics; chloramphenicol, rifampicin, griseofulvin.

special instructions

Considering the possibility of individual intolerance to the drug, it is recommended to conduct a drug test to determine tolerance to it. To do this, apply a thin layer of gel to the skin of the elbow. The appearance of severe redness and itching indicates increased sensitivity to Dimexide.

If allergic reactions occur during treatment with the drug, the use of the drug is stopped and H1-histamine receptor blockers are prescribed.

Release form

Gel for external use 25% in aluminum or plastic tubes of 20, 30, 50, 100, 150, 200, 250 gil, 500 g each in a jar with a high-density polyethylene lid or in a bottle with a high-density polyethylene lid. Each tube, together with instructions for use of the medicinal product for medical use, is placed in a cardboard box. Each jar or bottle is accompanied by instructions for using the medicinal product for medical use. From 5 to 20 cans or bottles in a cardboard box (for hospitals).

Storage conditions

Store at a temperature not exceeding 25 °C. Keep out of the reach of children.

Best before date

2 years. Do not use after expiration date.

Conditions for dispensing from pharmacies

Without a doctor's prescription.

Name and address of the company - 194292, Russia, St. Petersburg, 5th Verkhniy lane, 19A AVZ S-P LLC, 141305, Russia, Moscow region, Sergiev Posad, st. Central, 1

Consumer complaints should be sent to the organization that carries out quality control: Pharmamed LLC, 194292, Russia, St. Petersburg, 5th Verkhniy lane, 19 A, tel., website: pharmamed.rf

Indications for use of Dimexide

Dimexide has been approved for medical use since 1971. Indications for use of the medicine:

• sprains;
• edema of various etiologies;
• purulent wounds;
• phlegmon;
• trophic ulcers;
• lymphostasis;
• burns;
• hemorrhages in the joints;
• thrombophlebitis (acute or chronic);
• eczema;
• erysipelas;
• diffuse streptoderma;
• keloid scars;
• discoid lupus erythematosus;
• limited scleroderma ;
• alopecia;
• pyoderma;
• erythema nodosum;
• furunculosis;
• acne.

According to the manufacturer's instructions, applications with Dimexide are prescribed for diseases of the musculoskeletal system such as deforming osteoarthritis (in case of damage to periarticular tissues), ankylosing spondylitis , rheumatoid arthritis , reactive synovitis , radiculitis . The drug is used in combination with other drugs and procedures.

Dimexide is effective for bruises and gout ; it is used to accelerate the resorption of traumatic infiltrates and to treat heel spurs.

For a number of neurological diseases, as well as when it is impossible to use oral forms of NSAIDs (for example, with peptic ulcer electrophoresis with Dimexide may be recommended This method of treatment is used when it is necessary to relieve joint pain, pain due to osteochondrosis or post-traumatic pain (including if the patient has a damaged nerve).

In skin plastic surgery, Dimexide is used for the preservation of skin homografts , as well as for the treatment of transplanted skin homo- and autografts .

In dental practice, the product is used for inflammatory processes in the maxillofacial area and inflammatory damage to the salivary glands , for pulpitis , periodontitis , periodontitis , arthritis/atrosis of the temporomandibular joint .

Indications for use in gynecology are colpitis , cervical erosion , endometritis , adnexitis , thrush , complications developing after gynecological operations and childbirth, etc.

Due to its bactericidal and anti-inflammatory properties, the drug is often used in cosmetology. A mask with Dimexide and Solcoseryl is considered one of the most effective remedies for wrinkles and the best replacement for mesotherapy and Botox , and compresses and wraps with the solution help reduce the appearance of cellulite . In addition, cosmetologists recommend the drug as an anti- acne .

Hair masks with natural oils and Dimexide reduce hair loss and stimulate hair growth.

Dimexide

Dosage form

Concentrate for preparing a solution for external use.

Compound

Dimethyl sulfoxide – 50, 100 ml

Description

Colorless transparent liquid or colorless crystals, odorless or with a weak specific odor. Hygroscopic.

Pharmacotherapeutic group

Anti-inflammatory agent for topical use

ATX code: M02AH0Z

Pharmacological properties

Pharmacodynamics

Anti-inflammatory drug for external use, inactivates hydroxyl radicals, improves the course of metabolic processes in the site of inflammation. It also has local anesthetic, analgesic and antimicrobial effects; has moderate fibrinolytic activity. Penetrates through the skin, mucous membranes, the membrane of microbial cells (increases their sensitivity to antibiotics) and other biological membranes, increases their permeability to drugs.

Pharmacokinetics

When a solution of dimethyl sulfoxide is applied to the skin, it is detected in the blood after 5 minutes, reaching its maximum concentration after 4-6 hours, maintaining an almost unchanged level for 1.5-3 days. Dimethyl sulfoxide is excreted in urine and feces, both unchanged and in the form of dimethyl sulfone.

Indications for use

As part of complex therapy: diseases of the musculoskeletal system: rheumatoid arthritis, ankylosing spondylitis (ankylosing spondylitis), deforming osteoarthritis (in the presence of damage to periarticular tissues), reactive synovitis; limited scleroderma, erythema nodosum, discoid lupus erythematosus, mycoses of the feet, keloid scars, thrombophlebitis, alopecia, eczema, streptoderma, erysipelas, bruises, sprains, traumatic infiltrates, purulent wounds, burns, radiculitis, trophic ulcers, acne, furunculosis; in skin plastic surgery – preservation of skin homografts.

Contraindications

Hypersensitivity, severe hepatic and/or renal failure, angina pectoris, severe atherosclerosis, glaucoma, cataracts, stroke, coma, myocardial infarction, pregnancy, breastfeeding. Do not administer to children under twelve years of age.

Use during pregnancy and breastfeeding

Use during pregnancy and breastfeeding is contraindicated.

Directions for use and doses

Externally, in the form of applications and irrigations (washes). Gauze wipes are moistened in a solution of the required concentration and applied to the affected areas for 20-30 minutes. A plastic film and cotton or linen cloth are placed on top of the napkin. The duration of applications is 10-15 days.

When treating erysipelas and trophic ulcers - in the form of a 30-50% solution in water, 50-100 ml 2-3 times a day.

For eczema, streptoderma - compresses with a 40-90% solution in water.

For local anesthesia for pain syndromes - a 25-50% solution in water in the form of compresses of 100-150 ml (depending on the area being treated) 2-3 times a day.

For facial skin and other highly sensitive areas, use 10-20-30% solutions in water.

In skin plastic surgery, a 5% solution in Ringer's solution is used as a preservative medium for storing skin homografts.

Purulent-necrotic and inflammatory foci and cavities are washed with less concentrated solutions.

Side effect

Allergic reactions, contact dermatitis, erythematous rashes, dry skin, mild burning, itchy dermatitis; rarely – bronchospasm.

Overdose

Symptoms: increased dose-dependent side effects. Treatment is symptomatic.

Interaction with other drugs

Increases absorption and enhances the effect of ethanol, insulin and other drugs. Compatible with heparin, antibacterial drugs, non-steroidal anti-inflammatory drugs. Increases the sensitivity of microorganisms to aminoglycoside and beta-lactam antibiotics; chloramphenicol, rifampicin, griseofulvin. Sensitizes the body to drugs for general anesthesia.

special instructions

Some patients smell garlic in the air they breathe. Before using the drug, it is necessary to test for tolerance to it. To do this, dimethyl sulfoxide of the required concentration is applied to the skin using a cotton swab soaked in it; the appearance of hyperemia and severe itching indicates hypersensitivity.

When stored at a temperature of 18 °C and below, crystallization of dimethyl sulfoxide occurs, which does not affect the quality of the drug. To melt the crystals, carefully heat the bottle with the drug in a water bath (water temperature no higher than 60 ° C).

Impact on the ability to drive vehicles and machinery

The use of the drug does not affect the ability to perform potentially hazardous activities that require increased concentration, special attention and speed of psychomotor reactions (driving vehicles, working with moving mechanisms, working as a dispatcher and operator).

Release form

Concentrate for preparing a solution for external use 99%.

50, 100 ml in orange glass bottles with a screw neck, sealed with polyethylene stoppers and screw caps. Each bottle with instructions for use is placed in a cardboard pack.

Best before date

2 years. Do not use after the expiration date.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Vacation conditions

Dispensed by prescription.

Contraindications

Contraindications for use:

• intolerance to the components of the drug;
• liver/kidney failure;
• stroke;
• severe atherosclerosis ;
• angina pectoris;
• myocardial infarction;
• cataract;
• glaucoma;
• coma;
• pregnancy;
• lactation.

When prescribing a drug, take into account the fact that it can enhance not only the activity, but also the severity of the toxic effects of a number of drugs.

When even a small amount of dimethyl sulfoxide is swallowed, as well as when used for applications in the oral cavity, the patient may experience stomach upset or intestinal spasms.

Instructions for use of Dimexide (Method and dosage)

Dimexide solution: instructions for use

A solution based on Dimexide concentrate (Dimexide Zhff, Dimexide Lugal) is used as a means of external therapy. It is used for washing affected body surfaces (irrigations) and in the form of applications.

Moisten a gauze pad in a solution of the required concentration and apply it to the affected area for 20-30 minutes. The top of the napkin is covered with plastic film and linen (or cotton) cloth. It is recommended to repeat the procedures 1-3 times/day (depending on the indications) for 10-15 days.

How to dilute Dimexide concentrate depends on the purpose for which the medicine is being prepared.

To treat trophic ulcers, a 30-50% solution of dimethyl sulfoxide is used (for one treatment, 50 to 100 ml of liquid is used), eczema - a solution with a concentration of 40-90%.

For local anesthesia, the drug is used 2 or 3 times a day in the form of compresses with a 25-50% solution. Single dose - from 100 to 150 ml.

For joint pain (for example, with atrosis of the knee joint), lotions on the joint with the drug diluted to the same concentration are indicated. Compresses with Dimexide for the knee or ankle are applied for 20-60 minutes. The course is designed for 15-20 procedures.

If the lesion is localized in a highly sensitive area of ​​the body, the concentrate is diluted to obtain a 10-30% solution.

For patients who have undergone skin plastic surgery, bandages impregnated with a 10-20% Dimexide solution are applied to the transplanted homo- and autografts immediately after the operation and subsequently until the transplant is permanently engrafted.

To preserve skin homografts, a 5% solution of DMSO in Ringer's solution is used.

Less concentrated solutions are used for washing inflammatory and purulent-necrotic lesions and cavities.

Gel Dimexide: instructions for use

The gel (ointment) is used as a means of external therapy to treat patients over 12 years of age.

The product is applied to the affected area of ​​the body in a thin layer from 1 to 3 rubles/day. Gel 50% is intended for treating the skin; for mucous membranes it is recommended to use gel 25%. The course lasts from 10 to 15 days. It can be repeated no earlier than 10 days later.

For diffuse streptoderma , eczema , as well as for local anesthesia, applications with gel (50%) in the form of compresses are used. The procedure is repeated 2-3 times during the day.

For thrombophlebitis, the patient is prescribed simultaneous applications of Dimexide with heparin gel or heparin ointment . Applications should be done 2-3 rubles/day. The course is designed for 10-15 procedures.

In skin plastic surgery, dressings with 25% gel are applied to skin homo- and autografts . The first bandage is applied immediately after the operation, and further procedures should be repeated until the implant is firmly engrafted.

How to dilute the drug for joints for gout?

For diseases of the rheumatic type (in particular, gout ), compresses with Dimexide can significantly reduce pain and quickly relieve inflammation in them.

Penetrating well into the tissue, the drug promotes the gradual dissolution of salt build-ups on the joints of the small bones of the foot and joints affected by the pathological process.

To prepare a compress, the concentrate is diluted in an equal volume of water at room temperature. Then a piece of gauze is folded into several layers, soaked in the resulting solution, applied to the sore spot and insulated with polyethylene, cotton cloth and a woolen scarf.

Exposure time is from 20 minutes to half an hour. Treatment, depending on the degree of joint damage, lasts from 10 days to 2 months.

Since Dimexide is a good transporter of other drugs, before using it, to enhance the effect, you can lubricate the sore joint with anti-inflammatory ointment/gel ( Bystrum-gel , Chondroxide and their analogues).

To relieve intense pain, Dimexide (30 ml) can be mixed with a two percent solution of Novocaine (50 ml). The bandage is applied in the same sequence. Exposure time is from 30 minutes to 1 hour.

How to dilute Dimexide for a compress for heel spurs?

With a heel spur, to alleviate the patient’s condition and improve his quality of life, Dimexide is used in small dosages in the form of compresses or rinses.

To prepare the solution, the concentrate is diluted with water in a ratio of 1:5. Then a napkin soaked in liquid is placed on the sore heel and a sock is put on top. Exposure time: 30 minutes.

The effect of the procedure will be more pronounced if you rub anti-inflammatory ointment into the sore spot 15 minutes before applying the compress.

of Hydrocortisone , Dropiredol , Novocaine , Analgin to the Dimexide solution . This composition gives the best anti-inflammatory and analgesic effect. The compress should be removed no later than after 40 minutes, otherwise skin irritation may occur.

Why is Dimexide used in pediatrics?

In children, Dimexide is used to treat diseases of the musculoskeletal system , inflammatory , purulent and ulcerative skin lesions , erysipelas , eczema , streptoderma , burns , as well as diseases of the upper respiratory tract .

Compresses with the drug warm up well, stop the inflammatory process and relieve coughs that irritate the throat. This treatment is appropriate for pharyngitis , tonsillitis , and sore throat .

The proportions of the Dimexide compress with Novocaine for cough are as follows: three to four parts of water to one part of the concentrate (the younger the child, the less concentrated the solution should be prepared).

To prepare the composition, you can use two parts of the concentrate: one part water, one part juice squeezed from aloe stems and two parts honey melted in a water bath. Before use, the mixture is slightly warmed.

Gauze folded five times and soaked in the resulting mixture is applied to the throat and secured first with polyethylene and cotton cloth, and then with a scarf. Remove the compress after 50 minutes (earlier if a burning sensation occurs).

It is better to carry out the procedure at night.

For bronchitis , compresses with Dimexide help relax the bronchi and improve blood circulation.

The instructions for a compress with Dimexide and Novocaine for a child are as follows: one tbsp. a spoonful of concentrate is diluted in the same volume of boiled/distilled water, then diclofenac sodium (one ampoule) and 10 ml of a two percent solution of Novocaine .

Gauze soaked in the product is applied to the feet, back (in the area of ​​the shoulder blades) and chest, covered with polyethylene and secured with a bandage (scarf). The child is covered with a blanket. The duration of the procedure is 30 minutes. Compresses are applied once a day for a week and only if the child has a normal temperature.

The medicine is used warm (but not hot!). When applying gauze to the chest, avoid the heart area.

Contraindications for use in pediatrics are pathologies of the heart, blood vessels, kidneys and liver, problems with the immune system, age under 12 years, elevated body temperature.

Application in gynecology: how to make tampons with Dimexide?

Dimexide is used in gynecology in the form of vaginal tampons. To prepare a medicinal mixture, one part of the concentrate is diluted in five parts of water, and then aloe juice, antibiotics or Lidase .

Ready-made tampons that women use for menstrual bleeding are not suitable for treatment, since they are often impregnated with various compounds that can react with dimethyl sulfoxide. Therefore, tampons should be made independently from sterile cotton wool.

The tampon should be inserted into the vagina in such a way that it can be easily removed. The active substance is quickly absorbed, penetrating the inflamed ovaries or uterus even with shallow injection.

The duration of each procedure, as well as the duration of the course, depend on the degree of neglect of the pathological process.

Propolis-D as an adjuvant .

Due to the presence of propolis and DMSO in these suppositories, they provide good pain relief, stop the inflammatory process, have an antibacterial effect, help strengthen the immune system and increase the effectiveness of basic therapy.

They should be used twice a day, one at a time, for 10-14 days.

Dimexide for hair

The use of Dimexide in combination with natural oils and vitamins helps improve the structure and accelerate hair growth. What is dimethyl sulfoxide? A conductor for other substances and a universal stimulator of metabolic processes.

Mask with Dimexide for oily hair: one part of Dimexide concentrate, one part of ampoule solutions of vitamins A and E, one part of lemon juice (the juice can be replaced with vodka, cognac or 70-degree alcohol if desired). This composition should be left on the hair for no more than half an hour.

A mask for oily hair based on Dimexide (1 teaspoon), macadamia oil (1 teaspoon), almond oil (1 teaspoon), eggs (1 piece), cognac (1 tablespoon) also earned good reviews from trichologists. ). The mixture is applied to the hair for half an hour, then washed off with shampoo and rinsed with water and lemon juice.

To prepare a mask for hair growth and strengthening hair follicles, you need to mix castor and burdock oils taken in equal volumes, add to them oil solutions of vitamins E and A (one ampoule each) and 5 drops of lemon juice. Mix the ingredients thoroughly and add 1 tbsp. a spoonful of Dimexide concentrate.

After the composition is applied to the hair roots, a plastic cap is put on the head and tied with a towel. After an hour (if a burning sensation occurs - immediately), the hair is washed with shampoo.

A similar composition in which lemon juice is replaced with the yolk of one egg also works well on hair.

To stimulate hair growth, use a mask with sea buckthorn oil. To prepare the composition, mix the heated oil with the concentrate in a 3:1 ratio. The mixture is rubbed into the hair roots, insulated with polyethylene and a towel, and washed off after an hour. Instead of a rinse aid, at the end of the procedure you can use apple cider vinegar diluted with water in a ratio of 1:10.

Reviews about Dimexide for hair growth are mostly positive, but it should be remembered that the drug is a powerful pharmaceutical that has a number of contraindications and can cause a fairly severe burn.

Dimexide for face

In facial cosmetology, Dimexide is used to improve the condition of aging skin, as well as to treat problematic skin prone to rashes.

A very effective remedy for combating wrinkles and rejuvenating the face is a mask made from Dimexide and Solcoseryl . To begin with, you should dilute one volume of concentrate in ten volumes of boiled water and thoroughly wipe your facial skin with this solution. Then Solcoseryl .

The duration of the procedure is one hour. During this entire time, the mask must be sprayed with warm water so that it does not harden. After an hour, the gel (or ointment) is removed with a damp cotton swab, and the skin is moisturized with cream.

To prevent wrinkles, the mask can be done 1-2 times a month, if there are deep wrinkles - once every three days for a month.

An equally popular care product is a face mask with Dimexide and melaleuca (tea tree) oil. This composition is good at treating purulent-inflammatory skin lesions.

To prepare the mask, you need to mix equal volumes of a 10% aqueous solution of Dimexide and essential oil. The product is applied to the face using a cotton sponge for several hours or overnight, and then the residue is washed off with warm water. If a burning sensation occurs, wash off the mask immediately.

Dimexide for acne

The easiest way to use it for acne is to daily wipe the acne- areas with Dimexide solution (DMSO concentration - no more than 10%). The procedure is repeated twice a day.

However, reviews indicate that better results can be achieved using more complex mixtures.

You can dissolve two Erythromycin in a 10% solution of the drug, or you can mix four tablespoons of concentrate with 50 ml of two percent salicylic alcohol , 40 ml of glycerin and the contents of 10 ampoules of a ten percent solution of Dioxidin.

Both formulations should be applied to problem areas of the skin twice a day.

A very powerful remedy for acne is a composition prepared from 40 ml of salicylic alcohol (2%), 10 tablets of Metronidazole , 10 capsules of Doxycycline , and 10 ml of Dimexide (the concentrate is added last).

Dimexide for cellulite

The drug has a vasodilating effect and helps restore metabolic processes throughout the body, which allows it to be used to combat cellulite.

To reduce the “orange peel”, the product is used in the form of applications and compresses, after mixing with distilled water. Optimal proportions are selected depending on the zone for which the drug will be used.

For the thighs, the concentrate is diluted with water in a ratio of 1:1, for the armpits, neck and arms - in a ratio of 1:20 or 1:10.

Then gauze soaked in the resulting solution is applied to problem areas, covered with polyethylene, insulated and left on the skin for 50 minutes. The course is designed for 12-15 procedures.

Alginate wraps with Dimexide and wraps with Dimexide and seaweed are very popular in cosmetology.

Before starting the wrap, it is recommended to take a warm shower (or bath) and cleanse the skin with a fine-grained scrub. Then the skin of problem areas of the body is wiped with a cotton pad soaked in Dimexide solution.

For women with sensitive skin, the drug should be diluted with one volume of concentrate in three volumes of distilled or boiled water. If there is no allergy to the medicine, it is used in its pure form.

To treat the legs and abdomen, 1 teaspoon of solution is enough. After applying Dimexide, an anti-cellulite agent is rubbed into the skin. When it is absorbed, begin preparing the alginate. Since the drug hardens quickly, it should be prepared very quickly.

Alginate diluted in water is distributed over the skin, wrapped on top with two layers of foil (cling film) and a terry towel. Exposure time is from 40 minutes to one hour. There is no need to rinse off the product after wrapping. Simply apply cosmetic milk or moisturizer to your legs and stomach.

Seaweed wraps are made using the same principle.

How to dilute Dimexide for boils

Inflammation of the skin glands, which develop into boils, is often accompanied by a local increase in temperature and tension on the skin surface. In order to relieve pain and reduce tissue tension due to growing inflammation, dilute Dimexide in warm water in the proportion of 1 ml of concentrate per 10 ml of clean water. Cotton pads are soaked in the resulting solution and applied to the boils. It is important not to rub, rub, or knead an unruptured boil. Safe use is considered to be simply applying a moistened swab to the inflamed area.

Interaction

DMSO increases absorption and enhances the effects of a number of other drugs (including insulin) and ethanol.

Compatible with NSAIDs, antibacterial drugs , heparin .

Increases the sensitivity of microflora to beta-lactam antibiotics and aminoglycosides , rifampicin , chloramphenicol , griseofulvin .

Sensitizes the body to general anesthesia.

special instructions

Some patients smell garlic in the air they breathe.

To determine possible individual intolerance to the drug, before using it, it is recommended to conduct a drug test (the solution is applied to the skin and the patient’s reaction is observed).

Evidence of increased sensitivity is itching and severe redness of the skin.

If during treatment with Dimexide the patient experiences allergic reactions , he should be prescribed an antihistamine .

Non-medical use of the drug or how to clean polyurethane foam?

One of the little-known properties of Dimexide is its ability to remove hardened polyurethane foam well.

To do this, the concentrate should be applied to a cotton swab or sponge, rub it into the surface on which the foam has fallen, and wait a few minutes until the foam begins to become covered with a well-peeling crust. If necessary, the manipulations are repeated several times.

It is necessary to work with rubber gloves so as not to burn the skin of your hands.

How to treat a burn from Dimexide?

You can get a burn from Dimexide if the drug is diluted incorrectly, as well as if it is used undiluted.

Photo of a burn with Dimexide:

What to do in case of a burn? A cabbage leaf applied to the burned area is good for soothing irritated skin (it can be secured with a bandage on top).

Panthenol diluted in water at room temperature . In case of severe burns, you can use ointment with corticosteroids ( Hydrocortisone or Prednisolone ).

How to take it correctly

Solution

The drug in the form of a solution is used externally. The product is washed over the affected areas of the body and used in the form of applications.

Dip a gauze cloth into the prepared solution and apply it to the damaged area for half an hour. Secure the top with a cloth. The procedure must be done 2-3 times a day for 12-14 days.

Gel

The gel can be used externally by patients over 12 years of age. Apply a thin layer of gel to the affected area. Carry out the procedure 1-3 times a day. The treatment course lasts from 12 to 14 days. If you need to resume the course, you should take a break for 10 days.

Analogs

Level 4 ATX code matches:
Dolobene

Nayatoks

Finalgon

Apizartron

Bee venom

Gavkamen

Menthol oil

Gum turpentine

Capsicam

Tizol

Camphor alcohol

Turpentine ointment

Formic alcohol

Mataren Plus

Dimethyl sulfoxide

Fast Relief

Synonyms: Dimexide-Lugal , Dimexide Zhff , Dimethyl sulfoxide .

Analogs with a similar mechanism of action: Alvipsal , Apifor , Artran , Boromenthol , Viprosal , Medical bile , Diclogen , Camphor alcohol , Camphor (ointment/oil), Capsicam , Carmolis , Kolkhuri , Kim , Mataren , Kuznetsov ointment , Pikhtanol , Revma-gel , Chondroxide , Honsurid , Chondroitin , Espol , Eftimethacin .

Reviews of Dimexide

Dimexide is a drug with unique chemical properties. Numerous reviews from doctors confirm the versatility of this remedy.

Dimexide quickly relieves inflammation, relieves pain well, restores the nutritional processes of cells and tissues, improves blood flow in blood vessels, has an antibacterial effect and promotes the dissolution of blood clots.

These properties make it possible to use Dimexide for the treatment of diseases of the musculoskeletal system (compresses are very effective for arthrosis of the ankle or knee joints ) and diseases of the upper respiratory tract , as well as infectious and inflammatory diseases in gynecology .

Reviews of the Dimexide gel are also positive: the product very quickly stops the inflammatory process, removes pus, treats acne, contusions, bruises, osteoarthritis , purulent wounds and thrombophlebitis .

Dimexide is also successfully used in cosmetology. Solcoseryl mask is an excellent alternative to expensive procedures for facial rejuvenation, and reviews of Dimexide for hair allow us to conclude that the use of the drug is one of the most affordable and effective ways to strengthen and activate hair growth.

There are a lot of good reviews about Dimexide for acne. The product “works” both independently and in combination with antibiotics . Some girls add concentrate (a few drops) to clay masks.

As a result, the skin brightens, inflammation dries out, and recovery of the affected areas is accelerated.

Another category of reviews is reviews of Dimexide for cellulite. The product works really well on orange peel. The effect of wraps and applications becomes noticeable after just a couple of procedures, while Dimexide costs significantly less than most anti-cellulite products.

Summarizing the reviews, we can draw the following conclusion - Dimexide is indispensable in a home medicine cabinet, but when using it for cosmetic purposes, it is very important to remember that this is primarily a medicine that has contraindications and can cause allergies and burns.

Medicine for children

The drug is approved for use by children over 12 years of age. It is prescribed for problems with the musculoskeletal system, ulcerative and purulent lesions of the skin, burns, eczema, and diseases of the upper respiratory tract.

The product is used for compresses, which provide excellent warmth, prevent the development of inflammatory processes, and eliminate an unpleasant cough. This method of treatment is suitable for sore throat and pharyngitis. It is best to do compresses before bed.

For bronchitis, this method allows you to improve blood circulation and improve the condition of the bronchi.

How much does Dimexide cost in a pharmacy?

Cost of the drug in Russian pharmacies

The price of Dimexide in ampoules (bottles) of 50 ml in Russian pharmacies is from 22 rubles. The cost of 100 ml bottles is from 36 rubles. The price of Dimexide gel is 172 rubles.

Price of Dimexide in Ukraine

The price of Dimexide solution (50 ml) is from 12 UAH. You can buy a 100 ml bottle of concentrate for an average of 21 UAH. Ukrainian pharmaceutical companies do not produce ointment (gel) Dimexide.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Dimexide gel for external use
  application 25% 30g LLC AVZ S-P/Pharmamed LLC 199 rub. order

Pharmacy Dialogue

• Dimexide gel (tube 25% 30g) Pharmamed/AVZ S-P LLC

  RUB 216 order

• Dimexide (bottle 100ml) TCPP

  110 rub. order

• Dimexide gel (tube 25% 30g) Farmamed

  RUB 191 order

• Dimexide (bottle 100ml) Tula FF

  119 RUR order

• Dimexide (100ml bottle (plastic))Iodine technologies and marketing

  102 RUR order

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Pharmacy24

• Dimexide 50 ml solution PAT "Lubnipharm", Ukraine
  12 UAH. order
• Dimexide 50 ml solution PAT "Galichfarm", Ukraine

  15 UAH order

• Dimexide 50 ml solution TOV "DKP Pharm.Fabrika", Ukraine

  12 UAH order

• Dimexide 100 ml solution PAT "Lubnipharm", Ukraine

  21 UAH order

PaniPharmacy

• DIMEXID liquid Dimexide 50ml Ukraine, Galichfarm JSC

  16 UAH order

• DIMEXIDE liquid Dimexide liquid 50ml fl. Ukraine, Lubnyfarm PJSC

  13 UAH order

• Dimexide liquid Dimethyl sulfoxide 50ml Ukraine, GEZMP GP

  17 UAH order

• DIMEXIDE liquid Dimexide liquid 100ml fl. Ukraine, Lubnyfarm PJSC

  24 UAH order

• Dimexide liquid Dimexide solution for external approx. 50ml Ukraine, Zhytomyr FF LLC

  14 UAH order

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