Is it possible to drink Azithromycin and alcohol at the same time: negative consequences and risks

Alcohol and antibiotics are a combination that doctors do not recommend using. Harm to health and danger to life are guaranteed. In some situations, you cannot do without medication. Diseases always appear at the wrong time - on the eve of a holiday or celebration, symptoms suddenly appear, indicating an infectious disease.

In this situation, people prefer to isolate themselves from the crowd by refusing a sip of wine or beer. Others forget about taking medications for the evening, thinking that one evening does not solve anything. If you miss at least one dose, the entire result of treatment comes to naught, since the pathogen receives fertile soil for development. To defeat the bacteria, you will have to use stronger combinations, which harms the body, weakens it, making it vulnerable.

During antibacterial treatment, you are allowed to drink a glass of opinion. According to the results of laboratory studies, alcohol does not affect the use of antibiotic compounds. You should not expect any unpleasant side effects. Maintain boundaries without overusing them. Mixing treatment with alcohol is associated with the following consequences:

  • Development of an allergic reaction to components containing alcohol.
  • Redness of the skin, rash, increased sweating. A feeling of heat and temperature appears.
  • Intoxication of the whole body. Symptoms include vomiting, convulsions, severe headache and dizziness.
  • Liver dysfunction. Metabolism slows down. Recycling products cease to be excreted. The exchange is slow and atypical. This inhibits the work and function of systems, accumulates toxins and products, which affects well-being.
  • Blood pressure surges.

Everyone's reaction is different based on the combination. The mechanism of action is different, so it is difficult to give a definite answer. Call a doctor at home for a consultation. Please call our 24-hour service contact number. The operator will answer, ask questions and dispatch a team that will arrive within thirty minutes within the city. After examining the patient, the doctor will describe the picture, prescribe treatment, and help get out of intoxication. Some restrictions are imposed on the patient’s usual life and diet in order to get rid of unfavorable manifestations and return to the working rhythm.

Is it possible to drink alcohol with antibiotics?

You have been prescribed antibiotics, and you do not know whether you can drink a glass of wine or a glass of beer.
There is an opinion that you should not mix antibiotics and alcohol. For many who don’t like to drink, it has even become a convenient excuse for drinking. As soon as you say that you are taking antibiotics, the persuasion to drink immediately stops. However, legends are legends, but it doesn’t hurt to find out the truth. Let's figure out whether you can afford alcohol during antibacterial therapy. To begin with, a few words about antibiotics.
These are medications prescribed for bacterial infections. Different antibiotics have different mechanisms of action, but the result is the same - the death of bacteria or their inability to reproduce. Important. Antibiotics are not taken for viral diseases because they are unable to fight viruses.
Therefore, for flu and colds, taking antibiotics is not advisable. Many people, with symptoms of acute respiratory diseases, immediately grab antibiotics, which makes a big mistake. You can take these medications only with your doctor's permission. Like other medications, antibiotics have side effects. It is noteworthy that when combined with alcoholic beverages, the likelihood of side effects may increase. In addition, there is a danger of new adverse reactions. This, by the way, applies not only to antibiotics, but also to other medications, for example, sleeping pills, antiallergic drugs, sedatives, anti-inflammatory and painkillers.

Speaking about antibiotics and alcohol, the compatibility of which is questioned, it is important to note how alcohol interacts with the drug. Let's consider 2 main mechanisms due to which it is impossible to mix antibiotics and alcohol.

Metabolism of drugs

Any drug is metabolized in the body, that is, it goes through a series of transformations. The medicine begins to disintegrate already in the oral cavity. This process is enhanced in the gastrointestinal tract, where the drug is absorbed into the blood in the small intestine. The substance then passes through the liver, where it can undergo changes. The drug circulates in the bloodstream for some time, after which it is excreted in the urine (often in an altered form).

Now let's figure out what happens when you take alcohol while on antibiotic therapy. Like medications, alcohol is also metabolized. This happens in the liver with the help of specific enzymes. If the liver needs to cope with both alcohol and drugs at the same time, then the enzymes will either work too quickly or will not have time to do their job.

If the liver works too quickly, then the antibiotic will be destroyed prematurely and will not have time to fully realize the therapeutic effect. If liver function is slowed down, the antibiotic will accumulate in the blood too quickly, which leads to great toxicity of the drug.

Increased side effects

In some cases, the combination of alcohol with antibiotics can cause increased side effects or the appearance of new ones (from taking antibiotics). In particular, this is indicated for antibiotics that, for example, cause drowsiness. If you also drink alcohol, your drowsiness will increase. However, in addition to increasing the main side effects (which are indicated in the instructions for the drug), new ones may also appear. Often these are headaches, nausea, heart rhythm disturbances, intestinal disorders and abdominal pain.

Important: antibiotic resistance. Bacteria, like any other living organisms, evolve, adapting to new environmental conditions. In this case, they are able to adapt to the action of antibiotics. This is how antibiotic resistance develops—the resistance of certain types of bacteria to one or another type of antibiotic. Currently, this is one of the most serious medical problems, as resistant bacteria are becoming more and more, and the search for new antibiotics is difficult. Uncontrolled use of antibiotics is one of the reasons for bacterial resistance. Often patients stop taking the medication on their own as soon as they feel improvement. You can't do this with antibiotics. It is important to drink the entire course prescribed by the doctor, even if you feel significant relief “ahead of schedule.”

Dangerous side effects of azithromycin

Most people take azithromycin without side effects, but it can cause serious side effects. Serious reactions to azithromycin:

  • difficulty breathing or swallowing;
  • swelling of the throat, lips, tongue, or face;
  • cardiopalmus;
  • hives, itching, or skin rash;
  • fever not related to the original infection;
  • liver problems.

Drinking alcohol may make it difficult to detect these serious side effects. For example, a person may not notice weakness from the drug if they think they simply drank too much alcohol. A person may also think that abdominal pain is caused by a hangover rather than a reaction to azithromycin.

What happens if you drink alcohol with antibiotics?

Let's look at some of the negative consequences of taking alcohol and antibiotics at the same time. Let us immediately note that such phenomena may not be observed, but we are obliged to tell the reader about this, since such reactions occur in medical practice.

  • Liver dysfunction . If you have a healthy liver, you may not feel the effects of mixing alcohol with antibiotics. However, be aware that the liver experiences a double burden of processing both alcohol and the drug.
  • Disturbances in the functioning of the nervous system . In some people, alcohol in combination with antibiotics causes significant disturbances in the central and peripheral nervous system. In particular, this is expressed by headaches, dizziness, nausea and even convulsions.
  • Sleep disorder . Disturbances may occur up to the reversal of day and night.
  • Cardiovascular disorders . Most often this is a change in blood pressure (both upward and downward).
  • Allergic reactions . In rare cases, antibiotics and alcohol can cause severe allergic reactions, including anaphylactic shock. The latter is a serious condition that threatens human life. In this case, you need to call an ambulance.
  • Digestive tract disorders . Combining antibacterial drugs with alcohol may cause indigestion, abdominal pain, and diarrhea.

How many days after taking antibiotics can you drink alcohol?

How much should you not drink after taking antibiotics? This is also one of the most common questions asked by patients forced to take antibacterial drugs. In this case, much depends on the specific drug, namely, the time it takes to remove it from the body.

In most cases, it is enough to take a two-day break (48 hours) after taking antibiotics, after which you can indulge in alcohol. In some countries they recommend waiting 3 days. There is no consensus on this matter. The only thing that can be said for sure is that you need to wait at least 2 days.

Other drug interactions with azithromycin

Azithromycin may interfere with the way some medications and supplements work. A person should keep a list of all the vitamins, herbs, supplements and medications they take. This can help prevent dangerous interactions.

Azithromycin may interact with:

  • antacids containing aluminum or magnesium;
  • blood thinning drugs;
  • medicines taken to treat atrial fibrillation;
  • antiepileptic drugs;
  • nelfinavir (Viracept), an antiretroviral drug that treats HIV.

Why you shouldn't drink while on antibiotics

The medical literature (scientific articles, treatment recommendations, etc.), which talks about the harmfulness of combining antibacterial drugs with alcohol, indicates a number of negative phenomena that occur when taking alcoholic beverages and antibiotics at the same time. The negative consequences come down to two undesirable effects, namely:

  • Reduced effectiveness of antibacterial therapy . It is indicated that alcohol inhibits the antibacterial activity of antibiotics. Thus, the suppression of pathogenic microflora is less effective, which creates the need to extend treatment or find a new antibiotic.
  • Liver damage . With the simultaneous use of alcoholic beverages and antibiotics, a large load is placed on the liver tissue. The risk of intoxication not only of the liver, but also of the body increases, since the liver is a filter through which blood passes.

Let's figure out how true these statements are. And if an antibiotic and alcohol have already been mixed, what will happen to the body?

As for reducing the effectiveness of antibiotic therapy, such a danger really exists. But this applies not only to antibiotics, but also to other medications. It is noteworthy that there is still no convincing data regarding the negative effects of alcohol on various groups of antibiotics. In one animal study, no interaction between antibiotics and alcohol was observed. A study in humans did not show a significant decrease in the effectiveness of antibacterial therapy.

However, the instructions for such drugs state in black and white that it is advisable to abstain from drinking alcohol. Experts say that not enough research has been done on this issue, so it is better to stay away from alcohol while taking antibiotics. In addition, in the studies conducted, volunteers were given small doses of alcohol, which most likely do not have a significant effect on the metabolism of pharmacological drugs. Therefore, to the question of whether you can drink if you take antibiotics, the answer is still negative.

To summarize the above, we can identify 5 main reasons why it is undesirable to combine antibiotics and alcohol:

  1. Deterioration of metabolic processes . Alcoholic drinks impair the absorption of nutrients, vitamins, minerals, and medications. This means that antibiotics will be less absorbed into the blood, which will reduce their effectiveness.
  2. Increased blood sugar . Alcohol is metabolized in the body to form sugars. This is a particularly dangerous situation for patients with diabetes. In addition, an increase in sugar levels during infectious diseases can only aggravate the course of the pathological process, because sugar is a substrate for pathogenic microorganisms.
  3. Decreased immunity . Drinking alcoholic beverages reduces the body's defenses. Thus, the infectious process will only intensify.
  4. Allergy . Combining antibiotics and alcohol increases the likelihood of allergic reactions such as skin rashes.
  5. Unpredictable consequences . Despite the contradictory evidence base, it is difficult to make predictions regarding the interaction of drugs with alcohol in each specific case. Perhaps this combination will lead to undesirable consequences for you.

Important: antibiotics and other medications. For the information of our readers, it is undesirable to combine antibiotics not only with alcohol, but also with some other medications. When prescribing antibacterial therapy, the doctor will definitely ask what medications the patient is currently taking. As a rule, antibiotics are not recommended to be combined with anticoagulants, anticonvulsants, some hypoglycemic drugs and other drugs. If for some reason the doctor forgot to ask about the medications you are taking, then do not hesitate to ask him this question.

What is azithromycin

The polysynthetic antibiotic azithromycin belongs to the azalide group. It is prescribed for the treatment of infectious and other diseases caused by bacterial lesions. List of diseases for which treatment with this drug is indicated:

  • otitis;
  • respiratory tract diseases;
  • genitourinary infections;
  • colds, respiratory diseases;
  • inflammation of the skin;
  • some pathologies affecting soft tissues

Contraindications to the use of the drug also include arrhythmia, kidney and liver diseases, myasthenia gravis, any adverse reactions that occur when taking the drug, the presence of allergic reactions to one of the components of the medication.

The treatment regimen when prescribing this drug cannot be violated; the dosage is strictly observed in accordance with the doctor’s instructions. It is unacceptable to start therapy on your own or interrupt it at your own request. The prohibition includes the simultaneous use of medication and any alcohol-containing drink, including non-alcoholic beer.

Antibiotics and beer

Or maybe beer with antibiotics, because of all alcoholic drinks this is the least “strong”? Indeed, beer is a low-alcohol drink. However, its insidiousness is that, as a rule, people drink a lot of beer. So, 100 ml of beer contains approximately 3-6 ml of pure alcohol. Thus, if you drink 0.5 liters of beer, then this is already 15-30 ml of ethanol. And if the beer is strong, then this is already 40-50 ml of alcohol.

You shouldn’t relax about non-alcoholic beer either, because it still contains some amount of alcohol. Therefore, if you are taking antibiotics (especially if it is a short-term course), then it is better to abstain from alcohol, even if it is beer. For the sake of your health, you can wait a week or two without a bottle of beer.

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Antibiotics and alcohol: myths

So, as mentioned above, the negative effect of alcohol on antibiotics is a debatable issue. No one has proven this yet. Medical recommendations regarding abstinence from drinking alcohol during antibacterial therapy are rather “insurance” against a possible negative effect.

There are several theories why doctors still prohibit drinking alcohol while taking antibiotics. One of these is that when treating sexually transmitted diseases, doctors in this way simply punished their patients for their dissolute lifestyle.

There is a second interesting story related to the shortage of penicillin during World War II. It was in Africa, where British troops were conducting military operations. For the doctors there, penicillin was worth its weight in gold. It got to the point that urine was taken from sick soldiers in order to isolate penicillin from it and reuse the drug. But if you drink beer at the same time, the volume of urine increases sharply, which complicates the process of excreting the medicine from the urine. Therefore, patients who were prescribed an antibiotic were prohibited from drinking.

Augmentin and alcohol

Among other things, many patients may have a question: is it possible to drink alcohol while taking Augmentin? Is Augmentin compatible with beer, cognac and other alcoholic drinks? It is noteworthy that the American instructions for amoxicillin with clavulanic acid (Augmentin) do not list side effects associated with the combined use of alcohol. There have also not been any studies on the negative effects of combining amoxicillin with alcohol to reasonably prohibit patients from taking alcohol during antibiotic therapy.

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