Compound
- 100 grams of Cyclodinone drops include 193-288 mg of dry extract of common twig . Additional substances: polysorbate 20, 70% sorbitol , povidone , mint flavor, water, sodium sucrose dihydrate, 96% ethanol.
- 1 tablet of Cyclodinone contains 3.3-4.8 mg of dry extract of common twig . Additional substances: microcrystalline cellulose, indigotine, silicon dioxide, povidone , lactose monohydrate, starch, magnesium stearate, titanium dioxide, talc, iron oxide, macrogol 6000 , emethacrylic acid copolymer, ethacrylic acid copolymer.
Common twig fruit extract in Cyclodinone: how does it work and has its effectiveness been proven?
Vitex sacred, or common twig2, has been known since the 4th century BC. e. It was described by Hippocrates, who mentioned the benefits of the plant for uterine bleeding in women who have given birth. In 1539, vitex was described in the herbalism of Hieronymus Bock, a German biologist, and also at the beginning of the 6th century in the work “On Medicinal Substances” by the ancient Greek physician Dioscorides.
Today, there are more than 500 publications dedicated to chasteberry, a plant whose medicinal effects have been proven for years. It is included in the European and British pharmacopoeias (European Pharmacopoeia and BP).
An article about common twig and its effect on cycle disorders is contained in the Register of Medicines of Russia. The document states that the substance normalizes the content of sex hormones.
All information, including the history of use, mechanisms of action and effects of Vitex, is presented in the WHO monograph. Scientific articles give an idea of why Cyclodinone® is prescribed and thanks to which active components contained in the extract of dry chasteberry fruits, the drug has an effect. For example, diterpenes are the most active compounds that have a dopaminergic effect and are thus responsible for normalizing prolactin levels3. Common twig is not just a “weed”, and the extract from this plant is not just a “substance”. This is a well-studied drug with proven effects, established purpose, and developed dosages. The concept of phytoniring, used by , ensures quality control of the starting components, production, as well as the effectiveness of the final medicine.
You can read about the pharmacokinetics and how and why to take Cyclodinone® in the medical instructions for the drug.
Pharmacodynamics and pharmacokinetics
Is cyclodinone a hormonal drug?
The medicine is obtained from raw materials of plant origin, so it is not hormonal, but has a normalizing effect on the content of sex hormones.
Mechanism of action
The main component is ordinary twig . The dopaminergic effects of the drug eliminate hyperprolactinemia prolactin production . An increased content of prolactin disrupts the synthesis of gonadotropins , which can cause disturbances in the development of follicles, the corpus luteum and ovulation , which leads to an imbalance of estradiol and progesterone and can cause mastodynia and changes in the menstrual cycle.
Prolactin demonstrates a stimulating effect on the development of cells in the mammary glands and can stimulate the appearance of connective tissue, as well as cause an enlargement of the milk ducts.
prolactin content causes regression of pathological processes in the mammary gland and reduces pain. Correct production and regulation of the proportion of gonadotropic hormones normalizes the 2nd phase of the menstrual cycle.
When is it indicated to take Cyclodinone?
A medicine based on herbal raw materials is useful for treating sexual hormonal imbalances and the pathological conditions caused by them. Among them:
- mammalgia;
- long delays in the menstrual cycle, occurring periodically or constantly;
- prolonged absence of ovulation;
- high level of prolactin in test results;
- painful premenstrual syndrome.
In some cases, Cyclodinone helps stop prolonged lactation when breast milk is no longer needed.
Instructions for use of Cyclodinone (Method and dosage)
How to take the drug?
The drops are taken orally, after shaking the bottle. When taking all forms of release, you must wash them down with water.
Instructions for use of drops
The medicine in this form of release is taken orally, 40 drops once a day in the morning, washed down with water.
Cyclodinone tablets, instructions for use
The tablets are also taken orally, 1 piece once a day, in the morning, with water and without chewing.
Treatment is usually carried out over the course of a quarter, without interruption during menstruation. After relief of symptoms and improvement of the patient's condition, therapy should be continued for another 2-3 weeks.
If after completion of treatment complaints reappear, you should consult your doctor.
On what day of the cycle should you start taking the medication?
You can start taking the drug regardless of the duration of your menstrual cycle.
Note!
Description of the drug Cyclodinone table. p/o No. 30 on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
special instructions
depression while taking the medication, you should consult a doctor.
Drops are not recommended for use after anti-alcohol treatment has been completed.
Lactose intolerance (the tablets contain lactose) may cause diarrhea and pain in the epigastric region.
Patients with diabetes are allowed to take Cyclodinone both in drops and tablets, since a single dose of this drug contains up to 0.03 XE.
Does not affect the ability to drive vehicles.
Composition and dosage forms
Cyclodinone is intended for oral administration and is available in liquid and tablet forms:
- Drops: a solution containing ethyl alcohol, a light brown transparent liquid with a mint-herbal aroma. Packaged in dark glass bottles of 50 or 100 ml and secondary cardboard packaging. The vessels are equipped with special dispensing attachments.
- Tablets: light green, round, film-coated, packaged in blisters, the drug package contains 2 or 4 plates of 15 pcs. in each.
The active component of the drug is dry extract of common twig (Vitex agnus-castus L). The plant reduces the production of the hormone prolactin, thus stimulating the synthesis of gonadotropic hormones. In addition to the main substance, Cyclodinone drops contain alcohol, purified water, menthol and sweeteners. The tablets contain starch, lactose, other formative substances and stabilizers.
During long-term storage in the drug solution, a precipitate may appear. This feature does not affect the pharmacological properties and does not indicate a decrease in the quality of the drug.
Cyclodinone analogs
Level 4 ATC code matches:
Floragin
Agnucaston
Bioselac
Trioginal
Qi-Klim
Saguenite
Gynekohel
Mastodinon
Klimaktoplan
Mamoklam
Tazalok
Gynoflor E
Klimadinon
Klimadinon Uno
Klimalanin
The most common analogues of Cyclodinone are listed below: Prefemin , Agnukaston, Mastodinone, Bromocriptine, Indinol, Mastopol.
Reviews about Cyclodinone
Reviews from doctors about Cyclodinone indicate that the drug is quite effective when used to normalize the cycle. Reviews for mastopathy and menopause characterize the product on the positive side. Among the disadvantages, high prices and frequent negative effects on the skin with long-term use are often noted.
The online forum discussions do not reveal the difference in the clinical effects of different dosage forms (tablets, drops). It is also worth recalling that pregnancy is a strict contraindication for taking the drug.
Adverse reactions and contraindications
You should stop using Cyclodinone:
- under the age of 18;
- during pregnancy, breastfeeding;
- for pituitary tumors;
- intolerance to fructose, lactose;
- malignant neoplasms;
- allergic reactions to components.
Cyclodinone solution is prohibited for alcoholism or ethyl alcohol intolerance.
During treatment, the drug may occasionally cause adverse effects:
- headache;
- nausea;
- epigastric pain;
- acne;
- physical weakness.
If there is a sharp deterioration in health, you should interrupt treatment and undergo additional medical examination. It is also necessary to stop taking the drug if pregnancy occurs. Caution in therapy must be observed if patients have liver dysfunction or a history of epilepsy.
Cyclodinone price, where to buy
The price of Cyclodinone in tablets No. 30 (60 tablets per package is quite difficult to find on sale) in Russia is 430-640 rubles. The price of Cyclodinone drops 50 ml ranges from 450 to 510 rubles.
Ukraine gives approximately comparable prices: the cost of the indicated package of tablets reaches 340 hryvnia, and buying 50 ml of drops will cost no more than 260 hryvnia.
Despite the fact that Cyclodinone is not a hormonal drug, it is sold in pharmacies only by prescription.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Cyclodinone drops for oral administration 50mlBionorica GmbH
RUB 631 order
Pharmacy Dialogue
- Cyclodinone (tablet No. 30)Bionorica
RUB 864 order
- Cyclodinone (50ml drops)Bionorica
RUR 641 order
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Pharmacy24
- Cyclodinone N30 tablets Bionorica SE, Nimechchina
280 UAH. order - Cyclodinone 50 ml oral drops Bionorika SE, Nimechchina
214 UAH order
PaniPharmacy
- Cyclodinone liquid Cyclodinone drops 50ml Germany, Bionorica
226 UAH order
- Cyclodinone tablets Cyclodinone tablets No. 30 Germany, Bionorica
278 UAH order
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The drug Cyclodinone® - homeopathy, dietary supplement or not?
A common mistake is to assume that all herbal remedies are classified as dietary supplements or homeopathy.
Despite its plant origin, due to which the side effects of Cyclodinone are minimal, it is not classified as a dietary supplement. This is a medicine, as evidenced by its registration as a medicinal product. The registration number is included in the State Register of Medicines. Unlike dietary supplements, Cyclodinone® is characterized by strict adherence to the concentration of the active substance in each dose, be it drops or film-coated tablets. The instructions for the dietary supplement indicate the approximate content, which may vary from tablet to tablet. This is the main reason why supplements should be used only for prevention or as an adjuvant as part of complex therapy. The packages of dietary supplements indicate that they are not a medicine.
The indications for the use of Cyclodinone indicate that this drug is prescribed to women for treatment, and not just for the prevention of menstrual irregularities, PMS and mastodynia. The instructions were approved by the Ministry of Health of the Russian Federation1.
Among other things, the components in dietary supplements are not always well studied, unlike drugs whose effectiveness has been clinically proven. The answer to the question of whether Cyclodinone® is hormonal or not lies in its composition. It is based on an extract from the dried fruits of the common twig, a product of plant origin, which means there is definitely no talk of hormones in the composition.
