Biovestin-lacto, 7 pcs., 12 ml, emulsion for oral administration

Indications for use Biovestin

Biovestin is indicated for use if it is necessary to restore normal flora in the intestines after long-term use of antimicrobial drugs, as well as as part of complex care for.

• dysbacteriosis of varying severity and origin, which are caused by disturbances in the quantity and quality of one’s own flora in the absence of pathogenic bacteria;
• dysfunction of the gastrointestinal tract, accompanied by constipation, diarrhea, bloating;
• prenatal preparation;
• food allergies;
• treatment with hormonal drugs or radiation;
• respiratory diseases and their prevention;
• diagnosing vitamin deficiency and iron deficiency anemia;
• vaginosis of bacterial origin.

Probiotics series Biovestin

Baby food: taking care of what matters most | Functional nutrition | Probiotics series Biovestin

| Probiotics for B2B | Permits | Biovestin dietary supplement

Probiotics in the modern world are not a fad, but an urgent need for humans. Manufacturers mainly offer them in dry form - tablets or capsules.

But only in liquid form can a probiotic begin to work immediately after administration. It contains not just living, but active bifidobacteria, which immediately begin to restore the intestinal microflora.

Why can only a liquid probiotic help?

"Biovestin" from Bio-Vesta - intestinal health in a small bottle

• live active liquid bifidobacteria that begin to work immediately after administration
• restores intestinal microflora, launches its normal motility
• strengthens the immune system
• protects the liver from toxins
• helps prevent food allergies helps with poisoning rich in valuable metabolites, volatile fatty acids
• absolutely safe to take - only natural, healthy strains

How do we produce Biovestin?

"Biovestin"

A unique liquid probiotic created by scientists from the Koltsovo science city. Contains bifidobacterium strain in live active form - Bifidobacterium longum MC-42

.

The probiotic contains a colossal amount of these microorganisms vital for the intestines. Biovestin can be given to children from the first day of life. You need to consult a pediatrician - you can get it on our hotline.

Sold in two types of packaging - 7 bottles and 28 bottles.

Ingredients: skim milk, bifidobacteria starter Bifidum longum MC-42

Shelf life: 2.5 months

Where to buy Biovestin?

More details on the website Biovestin.ru

"Biovestin-lacto"

In addition to bifidobacteria, the probiotic contains lactobacilli strain L.Plantarum 8PA3

. It is this that can help the body to a greater extent while taking antibiotics - so it is best to take such a liquid probiotic during treatment. It is important to separate Biovestin-Lacto and medications for at least two hours. And after that, take the Biovestin course.

Biovestin-lakto can be given to children from one year of age, but it is necessary to consult a pediatrician.

Sold in two types of packaging - 7 bottles and 250 milliliters.

Ingredients: skim milk, lactobacterium starter Lactobacillus plantarum 8PA3

and
Bifidobacterium longum MS-42
Shelf life: 2.5 months

Where to buy Biovestin-lacto?

More details on the website Biovestin.ru

"Biovestin-A"

The liquid probiotic of the Biovestin-A series is ideal for daily use. Live and active bifidobacteria will help you easily cope with stress and fatigue, and also strengthen your immune system.

Sold in two types of packaging - 7 bottles, each with a volume of 12 milliliters and separate bottles of 50 and 250 milliliters.

Ingredients: skim milk, sodium bicarbonate, probiotic bifidobacteria starter ( Bifidobacterium longum strain MS-42

).

Shelf life: 3 months.

Where to buy Biovestin-A?

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Directions for use and dosage

Take Biovestin on an empty stomach before meals (about half an hour). This period of time is necessary for the maximum speed of delivery of the drug to the appropriate parts of the intestine from the stomach. It is possible to dilute a single dose in chilled milk, juice, water, so that taking it does not cause discomfort.

Biovestin is compatible with any medications, including antimicrobials. Accordingly, previously prescribed medications will not interfere with the use of a probiotic.

Course duration:

• prevention of dysbacteriosis: 2 times a year, 2–4 weeks;
• restoration of the number of beneficial bacteria: from 14 days (maximum duration: 3 months).

Daily dosage:

• children (age less than one year): no more than 1 ml per day;
• children (age more than a year, but less than 12 years): no more than 6 ml per day;
• adults: no more than 12 ml per day.

It should be remembered that an overdose of beneficial bacteria does not pose a danger, since Biovestin is absolutely physiological.

Side effects

According to laboratory studies and long-term practice of using the drug, it does not cause side effects, regardless of the patient’s age and medical history.

Contraindications

The use of Biovestin is contraindicated in cases of individual intolerance to lactose (milk protein), since the composition contains both lacto- and bifidobacteria.

Biovestin-lacto, 7 pcs., 12 ml, emulsion for oral administration

"Biovestin-lacto" is a complex preparation containing representatives of normal human microflora - bifidobacteria and lactobacilli. "Biovestin-lacto" contains 2 strains of bifidobacteria: the pharmacopoeial Bifidobacterium bifidum 792 and Bifidobacterium adolescentis MS-42, which have high antagonistic activity against opportunistic and pathogenic microorganisms and resistance to therapeutic doses of the most common antibiotics. In addition, “biovestin-lacto” contains 1 strain of lactobacilli, such as the pharmacopoeial Lactobacillus plantarum 8P AZ, known for its positive properties in the treatment of human dysbiosis.

INDICATIONS FOR USE Biovestin-lacto should be used to protect the intestinal microflora when using antibiotics and other antibacterial drugs.

In addition, Biovestin-lacto should be used in complex therapy for

• intestinal dysfunctions (diarrhea as a clinical manifestation of dysbiosis);
• dysbacteriosis of various origins, caused by the presence of opportunistic and pathogenic intestinal microflora;
• correction of the microflora of open mucous membranes (oral cavity);
• carrying out prenatal preparation;
• long-term receipt of hormonal and radiation therapy;
• respiratory infections and their prevention;
• food allergies;
• iron deficiency anemia, vitamin deficiency conditions, rickets;
• bacterial vaginosis;

METHOD OF APPLICATION AND DOSES It is advisable to take Biovestin-lacto 30 minutes before meals, so that its evacuation from the stomach to the underlying parts of the intestine occurs as quickly as possible. For more comfortable use, you can dilute a single dose in boiled chilled water, milk, juice. Biovestin-lacto is compatible with all medications, including antibiotics. Taking Biovestin-lakto does not require discontinuation of medications.

When eliminating dysbiosis caused by a lack of bifidobacteria and lactobacilli, the course of taking “Biovestin-Lacto” is 2 weeks. To protect the normal intestinal microflora while taking antibiotics, the course of treatment is the entire period of taking antibiotics.

Daily doses of “biovestin-lakto”:

• children from 1 year to 12 years - up to 6 ml per day;
• adults - up to 12 ml per day;

"Biovestin-lacto" is absolutely physiological for humans and its overdose is not dangerous.

CONTRAINDICATIONS Individual intolerance to milk protein.

RELEASE FORM The product is packaged in glass bottles of 12 ml.

STORAGE CONDITIONS AND SHELF LIFE “Biovestin-lacto” is stored in the refrigerator for 60 days, at a temperature of +2 +6 oC. When storing Biovestin-Lacto, a white film may appear on the inner wall of the bottle—remnants of milk fat. When the contents of the bottle are heated to room temperature, the film dissolves. Do not shake bottles with “biovestin-lacto” and do not heat them above +40oC. Opened bottles are stored in the refrigerator for no more than two days. Please note that Biovestin-Lacto, which contains lactobacilli, becomes more acidic over time, even when stored in the refrigerator. This is due to the active activity of lactobacilli in a wide temperature range, while the quality of the product is maintained

"Biovestin" live bifidobacteria

Additional information confirmed by voluntary certification.

Mandatory consumer information is placed on the packaging

Areas of use

• To prevent complications during antibiotic therapy and chemoradiotherapy.
• To correct the immune status, including in HIV-infected people.
• To restore normal intestinal microflora, incl. nasointestinal probe and rectal endoscopic method.
• To normalize microflora and improve the barrier function of human mucous membranes.
• To improve the motor-evacuation function of the digestive system, restore the condition of the mucous membrane of the digestive tract.
• To restore the activity of the immune system in often long-term ill children, often ill people, after acute infectious diseases, during seasonal epidemic diseases.
• To prevent and reduce the severity of viral diarrhea.
• For inflammatory diseases of the genitourinary system (cystitis, pyelonephritis, bacterial prostatitis, bacterial vaginosis, chronic salpingoophoritis).
• To correct lipid metabolism.
• To reduce the external and internal toxic load on the body, incl. as a hepatoprotective agent.
• To protect against intoxication by harmful environmental chemicals.
• For chronic stress, winter fatigue syndrome, chronic fatigue syndrome.
• To increase endurance and sports performance in athletes of various qualifications.

Mechanisms of action
of the dietary supplement Biovestin is an additional source of bifidobacteria and promotes the restoration of symbiont microflora (SM).

Immunomodulatory

Symbiont microflora has universal immunomodulatory properties. The main immunomodulatory mechanisms are provided by bifidobacteria and lactobacilli. Colonization of the intestinal epithelium by bifidobacteria during interaction on the surface of M-cells of Peyer's patches leads to stimulation of lymphoid tissue, enhancement of innate immune reactions of the cellular and humoral immunity, and activation of cytokine production. Secretory IgA, produced with the direct participation of the normal flora of the mucous membrane of the genital tract and oropharynx, is an important factor in local immunity. Bifidobacteria, in addition to activating the production of IgA, stimulate phagocytosis and the formation of interleukins and interferons.

Antimicrobial

SM, through bacterial metabolites, has a modulating effect on the production of cytokines in the intestine, prostaglandins, and leukotrienes. SM, in particular bifidobacteria, produce antimicrobial (in relation to pathogenic and opportunistic microflora (hereinafter referred to as PM and UPM) substances): bacteriocins, benzoic, mevalonic acids, methylhydantoin, antibiotic-like substances, spectrum of SCFA (SM.6,7. Interaction of parietal intestinal SM and epithelium ensures the attachment of the secretory component to immunoglobulin class A (IgA), which blocks the attachment of nonsymbiotic bacteria to epithelial cells and activates the synthesis of lysozyme.

Regenerative (restoration of the intestinal mucosa)

SM metabolites take an important part in the life of the intestinal mucosa. Volatile fatty acids are a source of nutrition for mucosal cells, as well as an energy substrate for colonocytes. Butyric acid, butyrate, and estrogen-like substances are involved in the regulation of proliferation and differentiation of the epithelium of the gastrointestinal mucosa.

Metabolic

Violation of one of the functions of the intestinal microbiocenosis entails disturbances of various types of metabolism, contributing to the emergence of a deficiency of micronutrients - vitamins, microelements, minerals. SM ensures the synthesis of B vitamins, vit. K, folic acid due to its own synthesis. SM highly contributes to the modulation of the mineral metabolism of sodium, potassium, calcium, magnesium, phosphorus, chlorine, iron, zinc, manganese, selenium, copper, etc. SCFAs produced by SM as energy substrates occupy a significant place in the daily energy balance of a person.

Detoxification

Symbiont microflora (SM) inactivates toxins and microflora aggression factors, reduces histamine synthesis by inhibiting histidine decarboxylation, which helps reduce the content of endogenous toxins in the intestine. The metabolic products of SM and SCFA contribute to the suppression of putrefactive processes and suppression of the formation of ammonia, aromatic amines, sulfides, and endogenous carcinogens.

SM performs a detoxification function against many exogenous potentially toxicogenic substances supplied with food, water, and air. Such as salts of heavy metals, pesticides, nitrates, food additives and other xenobiotics. SM also acts as a “natural sorbent”, accumulating toxic products and preventing them from entering the portal vein system.

In addition, SM has antimutagenic activity.
Hypolilipidemic
Components of SM metabolize fatty acids and cholesterol with the formation of coprostanone, coprostanol, cholestenone through the hydrogenation reaction of the 5th and 6th double bonds of the cholesterol core.

Bifidobacteria, in the presence of bile salts, promote the transition of taurine and glycine-containing bile acid amides into poorly soluble precipitates that bind colonic cholesterol, which ensures its excretion with feces, and reduces the release of cholesterol from liver cells.
Anti-stress
The anaerobic component of the symbiont microflora is involved in the synthesis and regulation of neurotransmitters: alpha-alanine, 5-aminovaleric and GABA, glutamate, serotonin, dopamine, etc. SM through bacterial metabolites activates the synthesis of serotonin in the intestine.

Barrier (protective)

SM prevents the colonization of the intestinal mucosa by the PM and UPM by ensuring colonization resistance due to the competition of normal flora elements for adhesion sites, the production of corresponding metabolites - SCFA, bacteriocins, and competition for food substrates. The interaction of SM with the humoral and cellular components of mucosal immunity prevents the colonization of the mucous membrane of the genital tract by foreign microorganisms and prevents their translocation to other biotopes. The same barrier mechanism also operates in the biotope of the mucous membrane of the oropharynx.

Bibliography:

1. Immunobiological drugs and prospects for their use in infectology / G.G. Onishchenko, V.A. Aleshkin, S.S. Afanasyev, V.V. Pospelov. - M.: State Educational Establishment VUNMC Ministry of Health of the Russian Federation, 2002.

2. Belousova E.A. Possibilities of lactolulose in the correction of intestinal microflora disorders / E.A. Belousova, N.A. Morozova // Pharmateka. -2008. ‐No. 1. -WITH.

3. Shulpeneva Yu.O. Excessive bacterial growth in the intestine: pathogenetic features and therapeutic approaches / Yu.O. Shulpeneva // RMJ. -2003. -T. 11. -No. 5(177). -P.281-284

4. Kalmykova A.I., Selyatitskaya V.G., Palchikova N.A., Bgatova N.P. Cellular and systemic mechanisms of action of probiotics. - Novosibirsk: Novosibirsk book publishing house, 2007. – 279 p.

5. Microbiocenoses and human health/edited by V.A. Aleshkina, S.S. Afanasyeva, A.V. Karaulova M., Dynasty Publishing House, 2015, 548 p.

6. Bondarenko V.M., Matsulevich T.V. Intestinal dysbiosis as a clinical and laboratory syndrome: current state of the problem. M.: GEOTAR-Media; 2006.

7. Doronin F.A., Shenderov B.A. Functional nutrition. - M.: Grant, 2002. - 296 p.

8. Current issues in the correction of intestinal microbiocenosis. Educational and methodological manual. St. Petersburg, 2012.

Bondarenko V.M., Matsulevich T.V. Intestinal dysbiosis as a clinical and laboratory syndrome: current state of the problem. M.: GEOTAR-Media; 2006.

9. Bondarenko V.M. The role of opportunistic bacteria in chronic processes of various localization / M.: Tver-Triad. – 2011; 88 p.

10. Shenderov B.A. Medical microbial ecology and functional nutrition. T.1: Microflora of humans and animals and its functions – M.: GRANT, 1998. -228 p.

11. Tkachenko E.I., Uspensky Yu.P. Nutrition, microbiocenosis and human intelligence. SPB.: SpetsLit-2006-590 p.

12. Arutyunov G. A., Kafarskaya L. I., Vlasenko V. K. et al. Intestinal biocenosis and cardiovascular continuum // Heart failure. – 2004.

13. Probiotics and prebiotics / World Gastroenterological Organization (WGO). Practical recommendations. 2008; 3. Petrov L.N. et al. Bacterial probiotics: biotechnology, clinic, selection algorithm / St. Petersburg: Federal State Unitary Enterprise Gos. Research Institute of OCB. – 2008; With. 31.

14. Grigoriev P.Ya., Yakovenko E.P. Violation of the normal composition of intestinal microflora, clinical significance and issues of therapy (methodological manual). -M., 2000. - 224 p.

15. Microbiocenoses and human health/edited by V.A. Aleshkina, S.S. Afanasyeva, A.V. Karaulova M., Dynasty Publishing House, 2015, 548 p.

16. Kulinenkov O.S. Pharmacological assistance to an athlete: correction of factors limiting sports performance. - Moscow: Soviet sport 2007. - 138 p.

How to open a bottle. How to dose the contents in drops

• Lift the cap cover according to fig. 1-2.
• Open from the side of the dotted notch on the cap.
• For drip dosing: pierce the membrane with two straws so that one touches the bottom of the bottle - fig. 4.
• Invert the bottle and dose according to the instructions, Fig. 5.

Dosing method

Age	O - 3 months.	3 months - 1 year	1-3 years	3-6 years	From 6 years and adults
Daily dose	0.5 ml 10 drops	1 ml 20 drops	3 ml By mark or ¼ fl	6 ml By mark or ½ fl.	12 ml 1/1 bottle

Recommended daily doses are taken in 1-2 doses with meals. The course of admission is 3-4 weeks. Before use, the contents of the bottle can be carefully mixed. To increase the effectiveness of use, it is recommended to take Biovestin 30 minutes before meals, or 1.5 hours after meals.

Contraindications: individual intolerance to the components of the product, intolerance to milk protein. Consult your physician before use. Children from birth to 14 years old need to consult a pediatrician.

Storage conditions: store at a temperature of (4±2) C. When stored in the refrigerator, a consistency with occasional inclusions of milk fat or a fatty film is allowed. When opening the package, a slight release of carbon dioxide is allowed, due to the technology used to obtain the product. After opening, store in the refrigerator in a tightly closed bottle for no more than one day. Shelf life: 75 days from the production date in unopened original packaging.

Hotline “BIO-WESTS”. The call is free within Russia.