Relanium, 5 mg/ml, solution for intravenous and intramuscular administration, 2 ml, 5 pcs.

Features of the impact

Relanium belongs to the category of anxiolytic tranquilizers. It has a depressing effect on the functions of the central nervous system, which is realized mainly in certain parts of the brain and the limbic system. Activates the inhibitory effect of a substance that inhibits the transmission of nerve impulses in the central nervous system - gamma-aminobutyric acid. It has an anxiolytic, sedative and hypnotic effect, relaxes muscles and relieves cramps.

Pharmacodynamics and pharmacokinetics

The active ingredient is diazepam . The mechanism of action is based on stimulation of benzodiazepine receptors. The drug has central muscle relaxant, anticonvulsant, sedative, and hypnotic effects. The effect on the amygdala complex in the limbic system has an anxiolytic effect , reducing the severity of anxiety, fear, emotional stress, and restlessness.

Relanium has a sedative effect due to its effect on the nonspecific nuclei of the thalamus and the reticular pharmaceutics of the brain stem. The drug reduces symptoms of neurological origin. The drug in the brain stem inhibits the cells of the reticular pharmacy , causing a hypnotic effect . Relanium enhances presynaptic inhibition, providing an anticonvulsant effect. Diazepam does not relieve excitation in the epileptic focus, but suppresses the spread of epileptogenic activity.

Thanks to the inhibition of polysynaptic spinal afferent inhibitory pathways, a muscle relaxant effect is achieved. The sympatholytic effect leads to dilation of the coronary vessels and a drop in blood pressure.

Relanium is able to increase the threshold of pain sensitivity, suppress vestibular, parasympathetic, sympathoadrenal paroxysms.

The drug reduces the secretion of gastric juice at night.

The effectiveness of the drug appears on days 2-7 of treatment. Relanium does not affect productive symptoms of psychological origin (affective disorders, hallucinations, delusions).

In chronic alcoholism and withdrawal syndrome, Relanium leads to a weakening of tremor, agitation, hallucinations, alcoholic delirium, and negativism .

In patients with paresthesia, arrhythmias, and cardialgia, the therapeutic effect is recorded by the end of the first week.

Composition and terms of sale

According to the instructions, the main active ingredient of the drug is diazepam, a derivative of benzodiazepine. It is produced mainly in the form of a solution for intramuscular or intravenous administration, transparent, yellow-green or colorless. 1 ml of the substance contains 5 mg of the active ingredient, 10 mg in the ampoule.

The solution is packaged in ampoules and cardboard packs of 10 pieces. Less commonly, medicine can be found in the form of rectal suppositories or tablets - they have a less pronounced, delayed effect, and therefore are less popular.

The most complete absorption of the active component of the drug is achieved when the solution is injected into the deltoid muscle.

Relanium in any form is available in pharmacies with a prescription.

After intramuscular administration, the drug is absorbed unevenly and rather slowly. Bioavailability is about 90%, the maximum concentration is observed after 30-90 minutes. With regular use, the peak therapeutic effect is achieved after 1-2 weeks, excreted in the urine by 70%, in feces by 10%.

Indications for use

Indications for the use of Relanium include the following diseases and pathological conditions:

• neuroses and neurotic disorders accompanied by anxiety;

• elimination of psychomotor agitation;
• epilepsy, seizures;
• increased muscle tone (tetanus, blood flow disturbances in the arteries of the brain);
• elimination of delirium and withdrawal syndrome in the treatment of chronic alcoholism;
• preparation for surgical interventions or diagnostic procedures requiring absolute calm of the patient;
• complex therapy for hypertension, if symptoms include increased anxiety and excitability;

• preeclampsia, eclampsia, labor facilitation;
• menopausal and hormonal imbalances in women.

If there are appropriate indications for use, Relanium is prescribed for any pathologies accompanied by disruption of the nervous system, increased excitability, anxiety, insomnia, etc.

Mode of application

The method of administering the drug and the question of how much solution to administer to the patient depend on his condition and manifestations of the disease.

1. Increased anxiety and excitability
   . The medicine is administered intravenously at 5-10 (maximum 20) mg into a large vein, slowly - the injection rate is 5 mg per minute. If necessary, the procedure can be repeated after 3-4 hours.

2. Tetanus
   . Relanium is administered at a dose of 10 mg intravenously or as a maximally deep injection, after which an additional 100 mg of the active substance diluted in a solution of sodium chloride or glucose is administered.
3. Epilepsy
   . 10-20 mg intravenously or as an injection; if necessary, the drug is re-administered after 3-4 hours in a similar dose.
4. Muscle spasm
   . The solution is administered intramuscularly, the dosage is 10 mg. When preparing for surgery or diagnostics, the injection is given an hour before the procedure.

Relanium tablets are most often used for neuroses, in cardiology and rheumatology, the starting dosage is 2-5 mg per day, if necessary it is increased to 10 mg.

Solution for intravenous and intramuscular administration Relanium (Relanium)

Instructions for medical use of the drug

Description of pharmacological action

Anxiolytic drug (tranquilizer), benzodiazepine derivative. Diazepam has a depressant effect on the central nervous system, occurring primarily in the thalamus, hypothalamus and limbic system. Enhances the inhibitory effect of gamma-aminobutyric acid (GABA), which is one of the main mediators of pre- and postsynaptic inhibition of the transmission of nerve impulses in the central nervous system. It has anxiolytic, sedative, hypnotic, muscle relaxant and anticonvulsant effects. The mechanism of action of diazepam is determined by stimulation of benzodiazepine receptors of the supramolecular GABA-benzodiazepine-chlorionophore receptor complex, which leads to activation of the GABA receptor, causing a decrease in the excitability of subcortical brain structures and inhibition of polysynaptic spinal reflexes.

Indications for use

Neurotic and neurosis-like disorders with anxiety (treatment). Relief of psychomotor agitation associated with anxiety. Relief of epileptic seizures and convulsive states of various etiologies. Conditions accompanied by increased muscle tone (tetanus, acute cerebrovascular accidents, etc.). Relief of withdrawal syndrome and delirium in alcoholism. For premedication and ataralgesia in combination with analgesics and other neurotropic drugs in various diagnostic procedures, in surgical and obstetric practice. In the complex therapy of hypertension, accompanied by anxiety, increased excitability, hypertensive crisis, vascular spasms, menopausal and menstrual disorders.

Release form

doses for intravenous and intralingual administration 5 mg/ml; ampoule 2 ml, cardboard pack 10; doses for intravenous and intralingual administration 5 mg/ml; ampoule 2 ml, cardboard pack 50; doses for intravenous and intralingual administration 5 mg/ml; ampoule 2 ml, cardboard pack 5; doses for intravenous and intralingual administration 5 mg/ml; dark glass ampoule 2 ml, cardboard pack 10; doses for intravenous and intralingual administration 5 mg/ml; dark glass ampoule 2 ml, cardboard pack 5; doses for intravenous and intralingual administration 5 mg/ml; dark glass ampoule 2 ml, cardboard pack 50;

Pharmacokinetics

After intravenous administration, diazepams are absorbed completely and unevenly, depending on the place of administration; when introduced into the delto-like meat, the absorption of the liquid is complete. Bioavailability becomes 90%. Cmax when administered intramuscularly is reached in 0.5-1.5 hours, with intravenous administration it takes 0.25 hours. Subdivision With steady stagnation, Css is reached in 1-2 years. Binding with blood plasma proteins becomes 98%. Diazepam and its metabolites penetrate the blood-brain and placental barrier and are found in breast milk at concentrations similar to 1/10 of the concentration in blood plasma. When the drug is repeatedly administered, the accumulation of diazepam and its active metabolites is avoided. Metabolism Metabolized in the liver through the isoenzymes CYP2C19, CYP3A4, CYP3A5 and CYP3A7 by 98-99% with the active metabolites of desmethyldiazepam and less active ones - temazepam and oxazepam. The T1/2 level of desmethyl diazepam becomes 30-100 years, diazepam - 9.5-12.4 years and oxazepam - 5-15 years. Excreted in nirk - 70% (in the form of glucuronides), in the unchanged form - 1-2%, and less than 10% - in feces. Treat benzodiazepines with trival T1 / 2. After administration of medication, metabolites remain in the blood for several days or even longer. Pharmacokіnetics in special Klinichy vipades T1 / 2 can be zbilshuvat in the new university - up to 30, at the Patzihtv Pochutic Vika - up to 100 years, in Patzyntiv with Pechinovo I Nirkoy - up to 4 DIB.

Use during pregnancy

The drug is contraindicated before use during pregnancy and during lactation. Relanium has a toxic effect on the fetus and promotes the risk of development of birth defects when gestation stagnates in the first trimester. Taking the drug in therapeutic doses later in pregnancy may cause depression of the fetal central nervous system. Continuous stagnation during pregnancy can lead to physical congestion—possible symptoms of diarrhea in the newborn. When administered with Relanium in doses greater than 30 mg for 15 years before or before bedtime, the newborn may experience dizziness (even to the point of apnea), decreased muscle tone, decreased arterial pressure, hypothermia, weak blood flow. octanny (“baby baby syndrome” ).

Contraindications for use

— Important form of myasthenia; - Coma; — Shock; — Postcutaneous glaucoma; — A history of evidence of drug addiction, alcohol abuse (due to alcohol withdrawal syndrome and delirium); — Sleep apnea syndrome; — Alcohol intoxication level of varying degrees of severity; — Acute intoxication by medicinal means, which produces a galmic effect on the central nervous system (narcotic, drug and psychotropic means); — Important chronic obstructive illnesses (risk of progression of respiratory failure); — Gostra dikhalna insufficiency; — Childhood up to 30 days inclusive; — Vagity (especially the 1st and 3rd trimesters); — Lactation period (breastfeeding); — Increased sensitivity to benzodiazepines. Use caution in case of absence seizures (petit mal) or Lennox-Gastaut syndrome (if administered intravenously, it can provoke the development of tonic status epilepticus), epilepsy or epileptic seizures in the anamnesis (the beginning of treatment with diazepam or a severe Administration may accelerate the development of seizures or status epilepticus) , liver and/or nitric insufficiency, cerebral and spinal ataxia, with hyperkinesis, addiction to psychotropic drugs, with depression, organic diseases of the brain (possible paradoxical reactions), with hypoproteinemia, elderly patients.

Side effects

On the side of the central nervous system and peripheral nervous system: on the scalp (especially in patients with frailty) - drowsiness, confusion, fatigue, impaired concentration, ataxia, disorientation, dullness emotions, increased mental and emotional reactions, anterograde amnesia (develops more often, not when taking other benzodiazepines); rarely - headache, euphoria, depression, tremor, catalepsy, fluid confusion, dystonic extrapyramidal reactions (uncontrolled collapse), asthenia, muscle weakness, hyporeflexia, dysarthra Iya; in several episodes - paradoxical reactions (surges of aggression, psychomotor restlessness, fear, suicidal urges, muscle spasm, confusion, hallucinations, anxiety, sleep disturbance). On the side of the hematopoietic system: leukopenia, neutropenia, agranulocytosis (chills, hyperthermia, sore throat, severe fatigue or weakness), anemia, thrombocytopenia. On the side of the herbal system: dry mouth or hypersalivation, baking, gagging, gastralgia, boredom, vomiting, decreased appetite, constipation, impaired liver function, increased activity of liver transaminases and LF, zhovtyan itsya. On the side of the cardiovascular system: arterial hypotension, tachycardia. On the side of the sectiform system: non-trimming or shading of the secti, impaired function of the ribs. On the side of the arterial system: increased or decreased libido, dysmenorrhea. On the side of the respiratory system: suppressed diarrhea (with an overly administered drug). Allergic reactions: skin whistling, itching. Local reactions: phlebitis or venous thrombosis (worminess, swelling, pain) at the injection site. Others: call, medical deposit; rarely - suppression of the respiratory center, impaired vision (diplopia), bulimia, low body weight. With a sharply changed dose or over-ingestion - sleep syndrome (excessive fatigue, headache, anxiety, fear, psychomotor restlessness, sleep disturbance, dysphoria, spasm of smooth muscles of internal organs and skeletal muscles aturis, depersonalization, excessive sweating, depression, boredom, vomiting , tremor, sleep disorders, including hyperacusis, paresthesia, photophobia, tachycardia, seizures, hallucinations, and rarely psychotic disorders). When diagnosed in obstetrics in newborns - muscle hypotension, hypothermia, dyspnea.

Directions for use and doses

As a method of stopping psychomotor restlessness associated with anxiety, 5-10 mg is prescribed intravenously; if necessary, after 3-4 years the drug is re-administered in the same dose. For the right treatment, 10 mg is prescribed intravenously or deeply intramuscularly, then intravenously inject 100 mg of diazepam in 500 ml of 0.9% sodium chloride or 5% glucose at a rate of 5-15 mg/year. In case of status epilepticus, 10-20 mg is prescribed intramuscularly or intravenously; if necessary, after 3-4 years the drug is re-administered in the same dose. To relieve spasm of skeletal muscles - 10 mg IM 1-2 years before surgery. In obstetrics, 10-20 mg is prescribed intramuscularly when the cervix is ​​open to 2-3 fingers. The newly universal PISLI of the 5th Tizhnya Zhitty (older than 30 days) is recognized as a 100-300 μg / kg of Masi Til to the maximum dosi of 5 mg, with the non-core introduction of repeat after 2-4 years (in the deposits of the Klinichny symptoms). For children aged 5 years and older, the drug should be administered intravenously at 1 mg daily 2-5 times up to a maximum dose of 10 mg; If necessary, administration can be repeated after 2-4 years.

Overdose

Symptoms: drowsiness, decreased speed of consciousness of varying severity, paradoxical awakening, decreased reflexes to areflexia, decreased response to painful stimuli, dysarthria, ataxia, blurred vision (nystagmus), tremor, brady. arterial pressure, decreased arterial pressure, collapse, decreased cardiac activity, decreased respiratory function , coma. Treatment: washing the shunt, forcing diuresis, taking active vugill; carrying out symptomatic therapy (stimulus therapy and AT), individual ventilation of the lungs. Hemodialysis is ineffective. The specific antidote is flumazenil, which is present in hospital patients. Flumazenil is not indicated in patients with epilepsy who are taking benzodiazepine treatment. In such episodes, the antagonistic action of benzodiazepines can provoke the development of epileptic seizures.

Interactions with other drugs

MAO inhibitors, strychnine and corazole antagonize the effects of relanium. With one-hour ingestion of relanium with narcotics, sedatives, opioid analgesics, other tranquilizers similar to benzodiazepine, muscle relaxants, drugs for deep anesthesia, antidepressants, neuroleptics, and Also, with ethanol, beware of a sharp increase in the depressant effect on the central nervous system. With one-hour treatment with cimetidine, disulfiram, erythromycin, fluoxetine, as well as with oral contraceptives and estrogen-containing drugs, which competitively inhibit liver metabolism (oxidation processes) - increased metabolism is possible Changes in diazepam and increase in its concentration in blood plasma. Isoniazid, ketoconazole and metoprolol also increase the metabolism of diazepam and increase its concentration in the blood plasma. Propranolol and valproic acid increase the concentration of diazepam in blood plasma. Rifampicin may induce the metabolism of diazepam, leading to changes in plasma concentrations. Enzyme inducers change the effectiveness of relanium. Some analgesics enhance the oppressive infusion of relanium on the central nervous system. With one-hour ingestion with hypotensive agents, the hypotensive effect may be enhanced. With one-hour treatment with clozapine, it is possible to worsen the depression. With one-hour stagnation of relanium with cardiac glycosides, it is possible to increase the concentration of the remaining blood syringes and develop digitalis intoxication (as a result of competitive binding with plasma proteins). Relanium reduces the effectiveness of levodopa in patients with parkinsonism. Omeprazole lasts longer than diazepam. Dihal analeptics and psychostimulants reduce the activity of Relanium. With one-hour stagnation with Relanium, an increase in the toxicity of zidovudine is possible. Theophylline (in low doses) can replace the sedative effect with Relanium. Premedication with Relanium allows you to change the dose of fentanyl that is given for initial general anesthesia, and speed up the time of initial anesthesia. Pharmaceutical interaction Relanium insanity in one syringe with other drugs.

Precautions for use

If diazepam is prescribed for severe depression, additional special care is required - it is possible to use the drug for the implementation of suicidal intentions. It is not recommended to carry out continuous in/infusion - sedimentation and adsorption of the drug by PVC materials of infusion cylinders and tubes may occur. It is unacceptably sharply applied to the drug due to the risk of “wheezing” syndrome, but in connection with the increased excretion of diazepam from the body, it manifests weaker expressions than other benzodiazepines. When patients experience such emergency reactions as aggressiveness, psychomotor restlessness, anxiety, feeling like fear, thoughts of self-destruction, hallucinations, increased pain in the stomach, sleepiness, deep sleep - rejoicing after the reason iti. Treatment with diazepam or a sudden dose of medication in patients with epilepsy or a history of epileptic seizures may accelerate the development of seizures or status epilepticus. It produces a toxic effect on the fetus and increases the risk of development of birth defects when gestation is stagnant in the first trimester. Taking therapeutic doses later in pregnancy may cause depression of the fetal central nervous system. Constant stagnation during pregnancy can lead to physical lassitude—possible symptoms of “wheeling” in a newborn. Children, especially young ones, are very sensitive to the oppressive effects of benzodiazepines on the central nervous system. Newborns are not recommended to take medications that prevent benzyl alcohol - a possible development of a toxic syndrome, which is manifested by metabolic acidosis, central nervous system depression, difficulty breathing, nicotine deficiency, hypotension and, possibly, epileptic seizures, as well as intracranial hemorrhage. Vikoristannya in doses greater than 30 mg for 15 years before bed or before bed can cause the newborn to suffer from nausea (pre-apnea), decreased muscle tone and blood pressure, hypothermia, weak wetness (so-called “baby baby syndrome”). . For summer patients, Relanium® should be administered with special caution and should not be overdosed. The administration of Relanium® into the arterial bed through a possible development of gangrene is contraindicated. It is important to carefully evaluate the relationship between the rhizica and the cortex if it is considered to be vaginal, as well as if you are ill from a diseased liver or liver.

Special instructions for use

With particular caution, diazepam should be used in cases of severe depression, since the drug can be used to implement suicidal intentions. Injection of the relanium trace into the great vein, along the length of 1 x half. on the skin 5 mg (1 ml) of the drug. It is not recommended to carry out continuous infusion/infusion - sedimentation and adsorption of the drug by PVC materials of infusion cylinders and tubes may occur. In case of liver or liver failure and chronic congestion, it is necessary to monitor the peripheral blood picture and the activity of liver enzymes. The risk of drug addiction increases with high doses of Relanium, and with significant drug use in patients who were previously addicted to alcohol or drugs. Without special need, the drug should not be left to stagnate. It is unacceptable to sharply administer treatment through the risk of cessation syndrome, however, when given diazepam, the manifestation of this syndrome is much weaker than in other benzodiazepines. When such emergency reactions occur in patients, such as aggressiveness, psychomotor restlessness, anxiety, fear, suicidal thoughts, hallucinations, increased pain in the stomach, sleepiness, superficial sleep, liking the trace. pripiniti. The use of Relanium or its rapid administration in patients with epilepsy or a history of epileptic seizures may accelerate the development of seizures or status epilepticus. With special care and not exceeding the recommended dose, Relanium® should be administered in patients with advanced age. If it is necessary to administer the drug in patients with liver disease, the relationship between the risk and cost of therapy should be assessed. Relanium does not transmit intra-arterially through the rhizic development of gangrene. In case of trival stasis of the drug, the possible development of a call. During the period of treatment, alcohol consumption is prohibited. Research in pediatrics Children, especially young adults, are very sensitive to the oppressive influx of benzodiazepines on the central nervous system. Newborns are not recommended to take medications that replace benzyl alcohol, as this can lead to a toxic syndrome manifested by metabolic acidosis, central nervous system depression, difficulty breathing, nitric deficiency, arterial hypotension and, possibly, epileptic seizures, as well as intracranial hemorrhage. Impact on the ability to drive vehicles and operate machinery Patients who are taking the drug off should avoid engaging in potentially unsafe activities that require increased attention and fluidity of psychomotor reactions.

Storage conditions

Protected in a bright place, at a temperature of 15-25 ° C.

Best before date

60 months

ATX classification:

N Nervous system

N05 Psycholeptics

N05B Anxiolytics

N05BA Benzodiazepine derivatives

N05BA01 Diazepam

Use in children

The drug is used in obstetrics and pediatrics for psychosomatic, spastic, reactive disorders, and can be prescribed to children from 5 weeks. The solution is administered intravenously, slowly, the dose is calculated depending on body weight - 100-300 mcg per kilogram. Repeated administration is allowed no earlier than after 2 hours.

After the first administration of Relanium, it is necessary to monitor the patient’s reaction.

Repeated injections or increasing the dosage are possible only if the active substance is well tolerated.

For children over 5 years of age, the medicine is prescribed in tablets or in the form of a solution that is administered intravenously. The maximum dosage is 10 mg; when administered intravenously, it is important to administer it at a rate of no more than 1 mg in 2-5 minutes.

Use during pregnancy

The active ingredient of the drug penetrates the placental barrier and has a teratogenic effect, increasing the risk of intrauterine defects in the fetus. The use of Relanium in the last months of pregnancy can cause depression of the nervous system in the child. Constant use during pregnancy can cause signs of withdrawal syndrome in the newborn.

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The use of the active substance in an amount of more than 30 mg 15 hours before labor or during labor can cause respiratory depression, decreased muscle tone and blood pressure in the newborn.

Contraindications

Relanium is considered a potent drug that has a number of contraindications for use:

• myasthenia gravis in severe form;
• shock and coma;
• angle-closure glaucoma;
• addiction to drugs and alcohol (with the exception of treatment of withdrawal syndrome and alcoholic delirium);
• nocturnal apnea syndrome;
• alcohol intoxication;

• obstructive diseases of the respiratory system, respiratory failure;
• intoxication with medications, especially those that have a depressing effect on the function of the nervous system;
• children up to a month old;
• individual hypersensitivity to benzodiazepines and their derivatives.

Use with caution in severe renal and hepatic dysfunction, depression, organic brain disorders, Lennox-Gastaut syndrome, ataxia, and in old age.

Side effects

Treatment with Relanium can cause side effects from various organs and systems. The most common ones include:

• drowsiness, decreased performance;

• muscle hypotonicity;
• decrease in blood pressure;
• weakening of sexual desire;
• allergic manifestations;
• disturbances of speech and visual function;
• confusion, disorientation;
• bradycardia, tachycardia;

• cold extremities;
• thrombosis;
• dry mouth;
• digestive dysfunction;
• paradoxical reactions (increased excitability, insomnia, tremor);
• changes in laboratory blood parameters.

If dosages are observed, adverse reactions are rare, but during therapy the patient requires medical supervision. If adverse reactions develop, you must immediately stop treatment and consult a specialist.

Overdose

Manifested by confusion, drowsiness, decreased reflexes, paradoxical arousal, deep sleep, reduced response to painful stimulation, stupor, areflexia , impaired visual perception, apnea, severe weakness, shortness of breath, bradycardia, tremor, nystagmus, collapse, drop in blood pressure, respiratory depression , cardiac activity, coma.

Therapy involves forced diuresis , gastric lavage, taking enterosorbents, maintaining body functions, and mechanical ventilation.

The specific antagonist is flumazenil, used exclusively in hospital settings. Flumazenil is not prescribed to patients with epilepsy who are taking benzodiazepines (the drug may provoke an epileptic seizure). Hemodialysis is not effective in case of overdose.

special instructions

When prescribing the drug to children, debilitated and elderly people, medical supervision is necessary, as respiratory function disorders are possible.

The drug can cause coordination problems, drowsiness and a decrease in cognitive functions, therefore, when driving vehicles and performing hazardous activities, you need to be careful and, if possible, refuse such work.

Long-term use of Relanium is addictive, and abrupt cessation of use causes withdrawal syndrome, which is expressed by depression, cardiovascular disorders, paradoxical reactions: increased excitability, insomnia, irritability.

In obese patients, impaired hepatic and renal function, as well as elderly patients, the effect of the active substance may last longer due to the extended elimination period. To avoid drug incompatibility, taking any drugs in combination with Relanium should be agreed with your doctor.

It is necessary to administer the medicine intravenously slowly - rapid administration can cause collapse in the patient. The use of the drug in combination with ethanol, narcotic drugs and drugs that depress the nervous system can be life-threatening.

Reviews from people

Oksana Stupchenko

:

When the doctor prescribed this medicine for me, she didn’t even write it down on my card, but wrote it down for my aunt so that no one would know that I was taking it; most likely, it would not be advisable for people to know what the medicine is; a young girl was drinking at that time. This was about 9 years ago. You need to drink it a little at a time, a quarter, but it didn’t help me with my problem. I even took a whole tablet and it didn’t affect my consciousness in any way. With alcohol it’s the same garbage, after half an hour I’m sober. The doctor herself, this one said that she drank it for a whole year, only then it helped her. Her son died, and she took it hard. But to be honest, the medicine is not very good, I know, if you take a small dose it can make you feel uneasy, it causes hallucinations. I myself have neurosis and phobia, because of this I drank it. So I’ve had a phobia for 11 years, but then I took Relanium for less than a month and quit. It has a bad effect on internal organs. By the way, neuroses occur due to problems with the thyroid gland and gastrointestinal tract, so check the thyroid gland and stomach, if there is duodenitis, then it can cause neurosis. I also have duodenitis and problems with the thyroid gland, the bouquet is shorter :). But medicines and herbs (for duodenitis) have not helped yet, and it has not become any easier.

Valery Dyachenko

:

With alcohol withdrawal syndrome, the best thing is that I drink for several days, I don’t crave alcohol at all (I used to drink like a horse), my sleep has returned to normal. I can’t stand phenazepam at all; I start vomiting after one tablet. And I can take 4 tablets of Relium at a time, well, I’m a little slow, but I feel great, really, to each his own! Katya tell me why do you need it? Is it something you’re used to or is it vital?

Analogs

Analogue drugs include drugs based on the active ingredient diazepam, which have similar indications for use.

Before replacing one drug with another, you should consult your doctor, as drugs may have different side effects and specific uses.

Similar drugs:

• Picamilon (Picamilonum) Oral tablets
• Phenibut Oral tablets
• Phenibut Substance-powder
• Oxazepam Oral tablets
• Diazepam Oral tablets
• Neurobutal Oral tablets
• Alzolam Tablets
• Sibazon solution for injections 0.5% Solution for intravenous and intramuscular administration
• Apo-Lorazepam Oral tablets
• Diazepam Dragee

** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Relanium, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.

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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Relanium is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!

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