Picamilon: main characteristics, contraindications

Indications for use of Picamilon

What are the pills for?

• prescribed for migraine and open-angle glaucoma ;
• asthenia , depressive disorders in older people, anxiety , emotional instability;
• Vegetative-vascular dystonia may be an indication for the use of the drug ;
• Picamilon tablets are prescribed for the treatment of alcoholism ;
• during mental and physical stress (for example, among athletes);
• injections of the drug help with cerebral circulatory disorders of varying severity;
• the medicine can be prescribed to children and adults in complex therapy for the treatment of urological diseases;
• with neuritis of the auditory nerve .

Picamilon

Picamilon (N-nicotinoyl-gamma-aminobutyric acid sodium salt) is a nootropic drug. In recent years, the scope of use of nootropics in medicine has expanded significantly: these drugs are in demand in psychiatry, neurology, narcology, geriatrics, and pediatrics. They are successfully used for disorders of cognitive functions (memory, attention, concentration, mental activity), for the rehabilitation of patients suffering from cerebrovascular accidents, chronic alcoholism, etc. One of the most prescribed nootropics is Picamilon. This drug was synthesized in 1969 at the All-Union Vitamin Research Institute, and it has been used in medicine since 1986. It is a derivative of nicotinic and gamma-aminobutyric (GABA) acids. Nicotinic acid is an active participant in the processes of cellular respiration, has a vasodilating, antihypoxic, antiplatelet effect, facilitates the penetration of the drug through the blood-brain barrier (GABA itself lacks this ability), and enhances the neurometabolic and neuroprotective effects of GABA. Picamilon has a positive effect on metabolic processes and blood flow in the cerebral cortex, and stimulates blood circulation in the coronary arteries. In terms of the power and duration of cerebrovascular action, the drug is significantly superior to the substances from which it is synthesized - nicotinic acid and GABA. In the fast pace of life dictated by the harsh reality of recent decades, Picamilon will be useful to a wide range of people: sick and healthy, young and old.

One of its most important qualities is the ability to quickly return reduced physical and mental performance to its previous level. The use of Picamilon for fatigue is widespread in absolutely healthy people who, due to increased stress load, require adequate pharmacological support. Picamilon makes it possible to reduce dosages or completely abandon prescribed medications. It combines well with other drugs in complex treatment algorithms for various diseases. Picamilon provides high compliance, has a positive safety profile, and exhibits virtually no clinically significant side effects, which allows it to be prescribed to women during pregnancy and breastfeeding, as well as used in pediatric practice. The drug reduces the increased vascular tone of the carotid and vertebral arteries, increases the intensity of cerebral blood flow, incl. in ischemic areas, has a protective effect on neurons of the cerebral cortex, protecting them from the aggressive effects of free radicals and oxygen starvation, and improves the lipid profile. Has a mild tranquilizing effect. It is not addictive and does not exhibit a muscle relaxant effect. Well tolerated by patients during a course of treatment.

Instructions for use of Picamilon (Method and dosage)

Depending on the course and type of disease, the doctor may prescribe a course of the drug in tablets or injections. In both cases, the medication is taken regardless of food intake.

Instructions for Picamilon tablets

For diseases of the cerebral vessels: the daily dose ranges from 60 to 150 mg, distributed into 2-3 doses per day, the course is 30-60 days.

For depression in elderly people: daily dose up to 120 mg, in 2-3 doses, course – 45-90 days.

For mental and physical stress: 60-80 mg per day, for one and a half months; for athletes, a similar dosage is 14 days.

For the treatment of alcoholism and during abstinence: 0.1-0.15 g per day, 6-7 days.

Picamilon injections

The solution is administered slowly intramuscularly or intravenously.

For chronic cerebrovascular disorders, the daily dose is from 20 to 40 mg of the drug. It is administered intravenously in the morning and intramuscularly in the evening. The course of treatment ranges from 15 days to a month.

To treat acute intoxication , a single injection of 5 mg per 1 kg of weight is given. To maintain the state of abstinence, 1.56 mg per kilogram of body weight per hour (4 hours in the morning and evening) in a volume of 2.5 liters of solution for infusion.

How to take the drug for children

For children from three to ten years old, the daily dose is 0.04 g, the drug is taken 2 times. For children over 10 years old – 0.06 g, divided into 3 doses. The course of treatment is from one to two months.

Description and main characteristics

The drug is produced in the form of tablets of 30, 50, 100 pieces. in each package, as well as in the form of a solution in ampoules for injections. The volume of one ampoule is 200 ml, including the main component - 20 ml.

The active ingredient of Picamilon (solution) is the sodium salt of gamma-aminobutyric acid: dosage 10 mg per 1 ml of solution. The composition also contains distilled water.

Along with the same active ingredient, the tablets contain additional components - starch, talc and organic calcium salt (stearate).

The drug is dispensed only with a prescription. Store in a cool, dark place - in the refrigerator. Storage at room temperature up to 25 degrees is allowed. The shelf life is 18 months from the date of production.

Picamilon analogs

Level 4 ATX code matches:
Bravinton

Acefen

Carnicetine

Pyracesin

Nooclerin

Semax

Piracetam

Olatropil

Fezam

Vinpocetine

Cerebrocurin

Cavinton Forte

Calcium hopantenate

Glutamic acid

Cephabol

Olanzapine

Cerebrolysate

Pramistar

Sidnocarb

Vinpotropil

The most common analogues are:

• Aminalon
• Ceregamon
• Amylonosar
• Bisaw
• Bifren
• Lutsetam
• Neurovin
• Neuro-Norm
• Nootropil
• Noofen
• Piracetam
• Soakson
• Phenibut
• Fenotropil
• Cerebrolysin

Analogs and prices in pharmacies

The selection of analogues is carried out by the attending physician in two cases: if Picamilon is insufficiently effective and if an allergy occurs to the components of the drug. Prices for medications that better cope with problems also depend on the manufacturer, packaging volume and region of sale.

Picamilon is used as part of complex therapy in the form of a drip solution or capsules. It proves its effectiveness in therapeutic practice in the treatment of vascular lesions, the central nervous system, urological lesions, alcoholism, and changes in mental state. The advantage of the medication is the possibility of use in pediatrics.

Reviews for Picamilon

There are good reviews about the drug on the forums. However, some found its action insufficiently effective. The medicine has proven itself well as part of complex therapy.

Feedback on children's admission

Despite the fact that the drug is not recommended for children under 3 years of age, many doctors prescribe it to young children from 2 years of age. The medicine does not cause allergies, there are practically no side effects. Parents are happy, children become calmer, and sleep returns to normal. For some, taking Picamilon stimulates speech development.

Reviews from doctors

Doctors speak well of the drug. But they insist that the medicine greatly affects blood circulation and metabolic processes in the brain, so it should not be used without a doctor’s prescription.

Contraindications and side effects

Absolute contraindications apply only to 3 cases:

• pregnancy (all trimesters);
• breastfeeding (all periods);
• children under 3 years old.

In other cases, use is possible, but in the presence of kidney disease and individual sensitivity to the active substances - with caution.

In most cases, the drug does not cause side effects. But sometimes there are consequences such as:

• headache;
• mood swings;
• irritability;
• nausea;
• skin rash and other allergic reactions.

Picamilon price, where to buy

Price for tablets 0.02 g in packs of 30 pcs. is about 100 rubles.

The price for 10 ampoules of 2 ml is about 150 rubles.

• Online pharmacies in RussiaRussia

ZdravCity

• Picamilon tablets 20 mg 30 pcs. Pharmstandard-Ufavita Ufimsky vitamin plant OJSC
  106 rub. order
• Picamilon tablets 50 mg 30 pcs. JSC Pharmstandard-UfaVITA

  114 RUR order

• Picamilon solution for intravenous and intramuscular injection. 50mg/ml 2ml 10 pcs. (bufus) JSC Pharmstandard-UfaVITA

  RUB 143 order

• Picamilon solution for oral administration with measuring tape. spoon 4 mg/ml 100 ml JSC Pharmstandard-Leksredstva

  RUB 168 order

• Picamilon tab. 0.05g 60pcs JSC Pharmstandard-UfaVITA

  RUB 187 order

Possible negative effects

The medicine in any form is most often well tolerated by patients. Negative side effects are rare. With long-term use and increased dosages, the following are possible:

• irritability;
• increased excitability;
• headache;
• dizziness;
• nausea and vomiting.

With increased sensitivity, allergic reactions are likely to occur in the form of skin rashes, itching, and redness. With uncontrolled use or significantly exceeding the prescribed doses, side effects may increase. In such cases, symptomatic therapy is carried out.