Melanin in foods: what it is responsible for and how to increase its level in the body


Eye color also depends on the depth and level of this natural pigment.
If melanin is present only in the fourth and fifth layers, then the person will have blue or blue eyes. When the pigment is located in the anterior layers of the iris, the eye color is brown or yellow-brown, and when the melanin is unevenly distributed in the anterior layers, the eye color is gray or green. Some people have a hereditary disorder of melanin synthesis called albinism. They either produce this pigment in small quantities or not at all. Such people, in addition to significant changes in appearance (almost white eyes and hair, colorless white skin, red eyes, etc.), often suffer from problems with hearing and vision and differ from ordinary people in a significantly weakened immune system.

When there is an excess of melanin, a person develops melanosis, which can be:

  • physiological - observed in those organs where melanin should be present (skin, hair, meninges, eyes);
  • pathological - observed in those organs where melanin is not normally found (intestines, mucous membranes, esophagus).

What is melanin responsible for in the body?

Have you ever wondered what gives your skin its color or causes discoloration on certain parts of your body? The root cause of all this is melanin, a brown to black pigment found in the skin, hair and iris of the eye.

Melanin is the reason for the variety of skin colors. Additionally, the pigment melanin also acts as a protective layer on the skin, protecting it from damage from ultraviolet rays (UV). The curiosity surrounding melanin stems from its cosmetic, social and protective effects on humans. https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.201701472R

Melanin (from the Greek melas, melanos - dark, black) is a dark brown or black pigment found in hair, skin, as well as in the vascular (including the iris) and retina of the eye. In addition, it is also found in internal organs.

Melanin

- a universal pigment that gives a characteristic shade to the texture of hair, the iris of the eyes and the skin tone of people and animals. It is produced by pigment cells called melanocytes present in the epidermis of the skin, hair, eyes and other parts of the body. Melanin is formed by the oxidation of an amino acid called tyrosine.

Melanocytes are located in the lower layer of the epidermis - these are the cells that produce the brown pigment melanin. This pigment accumulates in keratinocytes and darkens the skin. The process of melanogenesis is responsible for long-term pigmentation, which is designed to protect the epidermis from damage by UV radiation and ensure the functionality of other organs and tissues. In addition, researchers have discovered that melanin plays an important role in the immune system and the health of other vital body systems.

According to natural history research, changes in skin color are an adaptive mechanism. As humans moved through hot environments in search of food, the body had to find ways to cool down. This need for thermoregulation led to an increase in the number of sweat glands and a decrease in the amount of body hair, which in turn made the skin more vulnerable to intense sun, especially in areas near the equator.

Darker pigmentation is like natural sunscreen. Those who lived in colder climates had lighter skin because they experienced lower ultraviolet radiation and needed skin that allowed sunlight to help the body produce vitamin D naturally.

That is melanin

is a natural skin pigment. The color of hair, skin and eyes in humans and animals mainly depends on the type and amount of melanin they have. Special skin cells called melanocytes produce melanin.

We all have the same number of melanocytes, but some people produce more melanin than others. If these cells produce low amounts of melanin, the hair, skin and iris of the eyes can be very light. If cells produce more melanin, hair, skin and eyes will be darker. The amount of melanin produced by the body depends on genes.

When you are in the sun, your body produces more melanin. It helps protect the body from harmful ultraviolet (UV) rays. But this is not enough to completely protect your skin from the sun, which is why it is so important to always use sunscreen.

Research shows that people with darker skin are less likely to experience skin cancer than people with lighter skin. However, more research is needed to see if this is related to the amount of melanin in their skin.

There are 3 types of melanin

:

Melanin and eye color

The amount of pigment in the stroma of the iris determines the color of the eyes. Those with little or no pigment tend to have blue irises. With a little more pigment, eye color is green, while eyes with more melanin are brown. Lighter eyes tend to be more sensitive to sunlight and are at greater risk for other problems, including macular degeneration. In comparison, people with darker eyes may be at higher risk of developing cataracts or glaucoma.

In addition, melanin has many other functions and capabilities.

:

  • ensuring the neutralization of free radicals;
  • promoting the acceleration of biochemical processes and reactions;
  • eliminating the influence of stress factors;
  • stabilization of immune function;
  • maintaining ideal functioning of the thyroid gland and liver.

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Melanin production depends on many factors

:

  1. Genetic composition

    : Descendants of different ethnic races and cultures are genetically predisposed to produce a certain amount and color of melanin as an inherited trait.

  2. Exposure to ultraviolet radiation

    : Melanin production is largely dependent on stimulation of melanocytes by ultraviolet light. Melanin acts as a protective shield to prevent skin damage from ultraviolet rays. People exposed to the sun are likely to produce more melanin.

  3. Melanocyte size

    : The size of melanocytes can vary between individuals. This can cause a significant difference in melanin production in an individual.

Why is melanin so important?

Melanin, being the primary determinant of the human races, has been the notorious cause of cruel and indiscriminate actions towards humans since time immemorial. However, revolutionary discoveries in science have revealed the real benefits of melanin. Melanin acts as a natural defense against damage caused by the sun's harmful ultraviolet rays. Ultraviolet exposure is an environmental factor that contributes to the development of skin cancers such as squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and malignant melanoma. Melanin is produced as granules in melanocytes and helps absorb and distribute light energy from ultraviolet rays to protect the genetic material in cells.

Fluctuations in a person's hormonal or genetic makeup can disrupt the production and distribution of melanin and lead to skin diseases such as skin burns and other malignant diseases such as cancer and albinism.

Melanin production can also be affected by certain diseases, such as albinism, which is a genetic disorder in which a person is unable to produce melanin, and vitiligo, which is an autoimmune disease characterized by the progressive loss of melanocytes. People with albinism are vulnerable to skin cancer, especially if their skin is not protected from ultraviolet radiation.

Where is melanin formed?

Melanocytes are cells that synthesize melanin. They have a multifaceted body, long dendritic processes that branch between the skin cells.

Melanocytes can be located in the connective tissue structure of the skin.

Dermatologist Marty Gidon

Connective tissue melanocytes and epidermal melanocytes have generally similar properties: neural origin, melanosomes, melanin biosynthesis enzymes, etc.

Melanin-containing cells are also found in the brain, spinal cord, genital area, inner ear, adrenal medulla, iris, and hair follicles.

The scalp (the scalp) has the highest number of melanocytes. The number of these cells does not change much with age, but their productivity does. Melanin is produced in smaller quantities as we age.

At the same time, there are some gender differences: men have more such cells than women.

Many people mistakenly believe that people of the Negroid race have a much higher number of melanocytes than white-skinned people. But in reality it is almost the same.

In dark-skinned individuals, these cells differ in size (larger), the predominant type of pigment produced (eumelanins), and location (melanin granules are present in all layers of the epidermis, including in corneocytes).

Symptoms, causes and consequences of insufficient melanin

Melanin

is a vital pigment that produces a compound responsible for determining skin and hair color. Melanin deficiency can lead to several disorders and diseases. For example, the complete absence of melanin causes a condition called albinism. Melanin deficiency has previously been associated with various genetic abnormalities and birth defects.

There are almost ten different types of albinism, a condition that is inherited in an autosomal recessive manner. This means that both parents must have carried one copy of the mutated gene, and the offspring must have received two copies.

  1. Oculocutaneous albinism

    A hereditary disease leading to insufficient or complete absence of pigmentation in the skin, hair and eyes. Albinism is more likely to occur when both parents have the recessive genetic disorder, and it can occur to varying degrees in any ethnic group. People with this type of disorder have skin that is highly susceptible to sun damage and cancer, as well as vision abnormalities, including involuntary eye movements and sensitivity to light. Those with albinism should wear sunglasses to protect their eyes and use sunscreen.

  2. Vitiligo

    When certain parts of the skin lose pigment, the result is patches of white (no pigment) skin. Vitiligo is most noticeable in people with darker skin and usually appears between the ages of 20 and 30. Although the reason for the destruction of these specific melanocytes remains unclear, there are three possible patterns of depigmentation

    :

      Localized loss of pigmentation

      occurs in one or more areas.

  3. Segmental

    - pigmentation is lost on only one side of the body.

  4. Generalized

    - widespread loss of pigment.

  5. Other types of hypopigmentation

    Another cause of hypopigmentation is skin trauma such as burns or blisters. Depending on the extent, melanin loss can be severe. Treatment for this type of hypopigmentation includes the use of concealing cosmetics or corticosteroid creams. The good news is that pigment loss may not be permanent, but it will take time to recover.

Types of hyperpigmentation

Overproduction of melanin is a common condition for all skin types and can occur anywhere in the body. One of the ways it manifests itself is the appearance of sun spots on sun-exposed skin. Treatment can often reduce or remove these mostly harmless spots if they bother a person. Freckles are a hereditary trait that become more noticeable with more sun exposure during the hotter months. Melasma is the presence of brown patches on the skin, especially on the face. It is more common in women during pregnancy because it is triggered by hormones.

Let's note a few more interesting facts about melanin.

Study

: Melanin, Melanin

What happens when there is a deficiency of melanin?

A change in the concentration of a substance in tissues can provoke the development of pathologies such as Parkinson’s disease, vitiligo, albinism, etc.

In addition, melanocytes that produce melanin are the founders of malignant formation - melanoma.

If pigment synthesis is insufficient or completely absent, albinos are born - people who have white hair and skin.

In addition to their distinctive appearance, such individuals have problems with vision, hearing, and immune defense.

There are also cases when pigment disappears in certain areas of the skin, and peculiar white “islands” form on the epidermis. This condition is called vitiligo.

There is an assumption that it is provoked by:

  • nervous tension;
  • injuries, operations;
  • medicines;
  • chemical, sunburn;
  • chronic inflammatory processes on the skin;
  • endocrine, autoimmune disorders;
  • genetic predisposition;
  • necrotic phenomena.

Foods that increase melanin production

The pigment is produced only by the human body from the amino acid tyrosine. It can be obtained from certain products: soybeans, beans, pumpkin seeds, sesame seeds, grains, avocados, almonds, dates, legumes, greens.

How to increase melanin levels in the body

Melanin is a natural protector against ultraviolet (UV) rays. According to the American Cancer Society, people who have more melanin in their skin have a lower risk of sunburn and skin cancer. Tanning is a sign that the skin produces melanin. This is a way to protect the skin from damage. However, experts have also linked sun exposure, sunburn and tanning to skin damage and skin cancer.

No research has yet proven that food or dietary supplements can increase melanin levels in humans. However, consuming certain nutrients can help protect your skin from UV damage and skin cancer.

  • Tanning to Boost Melanin Levels

    Although melanin has some protective properties, tanning is not a safe way to increase melanin levels. According to the Skin Cancer Foundation, tanning, sunburn and sun exposure significantly increase your risk of developing skin cancer. Additionally, the Skin Cancer Foundation says people should not try to get a “base tan” before going on holiday or spending long periods in the sun. This pre-tanning does not protect against sunburn, but it increases skin damage and the likelihood of developing skin cancer.

    Even though people with darker skin have some natural UV protection, the American Academy of Dermatology says people of all skin tones can get skin cancer and need to protect their skin from the sun.

    A healthy diet can also help prevent skin cancer, as certain nutrients may provide some protection against skin cancer. Here are some nutrients that research shows may be helpful in producing more melanin in the body.

  • Tyrosine-rich foods

    Melanin is formed as a result of the oxidation of the amino acid tyrosine. In addition, tyrosine is also involved in the production of various neurotransmitters that ensure the transmission of nerve impulses. Since tyrosine is a precursor to melanin, including foods that contain tyrosine in your diet, such as eggs, meat, chicken, cheese, turkey, and whole grains, can help increase melanin production in the body. In some cases, tyrosine supplementation may be helpful, but specialist advice is necessary.

  • Antioxidants

    Antioxidants

    are substances that can slow down or prevent cell damage. In some cases, they may help prevent certain types of cancer. Some research suggests that antioxidants may help mediate UV damage to skin and skin cancer. The National Institutes of Health (NIH) suggests that eating more foods rich in antioxidants may help prevent some types of diseases.

    While antioxidants in food can be very beneficial, getting them from supplements is a controversial topic. Some evidence suggests that high doses of antioxidant supplements may cause health risks, including an increased likelihood of certain types of cancer. They may also interact with medications.

    Study

    : The Role of Antioxidants in Skin Cancer Prevention and Treatment, Antioxidants: In Depth

    Antioxidants have the greatest potential to increase melanin production. Although more research and high-quality trials are needed, some studies suggest that antioxidants may help. Micronutrients such as polyphenols or flavonoids, which we get from plants, serve as powerful antioxidants and can affect melanin levels. Some may help increase melanin, while others may decrease it.

    Consume more antioxidant-rich foods such as brightly colored vegetables, dark berries, dark chocolate and dark leafy greens to get more antioxidants. Taking vitamin and mineral supplements may also help.

  • Flavonoids

    Flavonoids are nutrients found in almost all fruits and vegetables. These compounds have demonstrated some antitumor properties. One study found that certain flavonoids may help prevent melanoma, the deadliest form of skin cancer. The researchers used several flavonoids, many of which are found in fruits, vegetables and green tea.

    While they may not increase the amount of melanin, consuming flavonoids is a great way to help protect your skin from damage.

    A person's genetics determines their natural melanin levels and skin color. However, researchers are looking for ways to increase the amount of melanin and help prevent skin cancer. A diet rich in antioxidants and flavonoids is a good way to protect against skin damage and skin cancer.

    Additionally, people of all skin tones should protect themselves from UV rays by using sunscreen daily and wearing sunglasses and hats when they are out in the sun for long periods of time.

    https://www.fda.gov/radiation-emitting-products/tanning/risks-tanning

  • Vitamin A

    Researchers suggest that vitamin A plays an important role in the production of melanin and is an important ingredient for healthy skin. We can get vitamin A from food, especially from beta-carotene-rich vegetables such as peas, spinach, sweet potatoes and carrots.

    Since vitamin A also acts as an antioxidant, some researchers are of the opinion that unlike any other vitamin, vitamin A may have an effect on melanin production. However, more research is still required to prove this.

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    However, claims that vitamin A increases melanin levels are still not reliable. However, some research suggests that taking vitamin A (especially retinol) may be beneficial for overall skin health. For example, according to a 2014 study, a certain type of carotenoids (the substance that gives orange, red and yellow vegetables their color) is found in vitamin A.

    You can increase the amount of vitamin A in your body by eating more foods rich in vitamin A, such as fish, meat, and orange vegetables (such as sweet potatoes, carrots, red peppers, tomatoes).

    In some cases, supplementation may be necessary. Because vitamin A is a fat-soluble vitamin, it can be stored in the body, which is why the National Institutes of Health recommends a daily intake of 900 mcg for men and 700 mcg for women. For children, the daily intake of vitamin A should be lower.

    Eat foods high in beta-carotene and vitamin A. Add orange and red vegetables to your diet, such as carrots, tomatoes, sweet potatoes, zucchini, and red bell peppers, and fruits, such as pumpkin, papaya, and melon.

    Carotene does not technically stimulate melanin production, but this fat-soluble pigment will accumulate in the skin, imparting a natural golden glow. The effect of beta-carotene on skin pigmentation appears to be most effective on lighter skin tones. https://academic.oup.com/jn/article/132/3/399/4687282

  • Vitamin E

    Also a vital vitamin for skin health. It works as an antioxidant and can affect melanin production. While there are no studies directly linking increased melanin to vitamin E, some studies do show that vitamin E may help protect skin from sun damage.

    You can increase the amount of vitamin E in the body by eating foods such as grains, nuts, seeds, vegetables, some fruits, asparagus, avocados, and corn.

  • Vitamin C

    Like vitamins A and E, vitamin C acts as an antioxidant. It can increase melanin production and protect the skin. There are no studies that directly link vitamin C to melanin production. However, some evidence suggests that vitamin C may enhance melanin production.

    Consuming foods rich in vitamin C, such as berries, citrus fruits and leafy green vegetables, can increase melanin production. Taking a vitamin C supplement may also be helpful.

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    Foods rich in both vitamin E and vitamin C include green leafy vegetables, tomatoes, berries and broccoli. These products have antioxidant properties, meaning they can help protect the skin from cell damage while promoting balanced melanin production. To get the highest levels of vitamins from fruits and vegetables, try to eat them raw.

    Herbal products such as turmeric, green tea and tea tree are high in polyphenoids and flavonoids and may optimize melanin production and help protect the skin. It's worth noting that there are currently no studies directly proving a link between any herbs and increased melanin production. However, there is no harm in trying some herbs that can potentially protect your skin and possibly boost your melanin levels. These herbs can be found in essential oils, dietary supplements, and teas.

  • Fatty fish

    Increased melanin production reduces the skin's ability to absorb vitamin D when naturally exposed to sunlight. This is an essential vitamin for maintaining healthy bones and blood, so it is important to supplement your diet with foods containing this vitamin.

    Include fish such as salmon, catfish, mackerel and herring in your diet. Canned fish such as tuna and sardines are also good sources, as are fish oils, including cod liver oil. Use them sparingly so as not to exceed your total mercury intake.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356951/

Although some studies may suggest that there are several methods to increase melanin production, they are not completely reliable at this time. However, eating healthy foods or supplements that contain certain vitamins and minerals, such as vitamins A, C and E, can help maintain healthy skin and reduce the risk of developing skin cancer, some studies suggest.

At the same time, there is no convincing evidence that any nutrient or vitamin reliably increases melanin in people. The only sure way to reduce your risk of developing skin cancer is to avoid overexposure to ultraviolet rays and use a high-quality sunscreen.

Side effects of excess melanin

It is worth noting that excess melanin has undesirable consequences

:

  • Vitamin D deficiency

    Excess melanin can lead to vitamin D deficiency. Vitamin D synthesis is triggered by sunlight as it converts the precursor to its active form. People with excess melanin are more susceptible to vitamin D deficiency because melanin acts as a shield to prevent the absorption of sunlight needed to form vitamin D. It can also cause other diseases such as osteoporosis and rickets.

    Vitamin D plays an important role in the absorption of calcium and phosphorus and is also beneficial for maintaining bones and skeletal structure of the body. https://pubmed.ncbi.nlm.nih.gov/28620422/

  • Hyperpigmentation

    Excessive sun exposure in an attempt to increase melanin levels can lead to hyperpigmentation, causing dark spots, melasma and age spots.

Melanin and melatonin - what are the differences?

Due to the similarity in names, many people confuse melanin and melatonin. Also quite often there are questions of the following nature: what is it, why is it taken, does it affect sleep, etc.

Let's start with the fact that melanin and melatonin are 2 completely different substances.

Melanin, as stated above, is a high-molecular pigment that is responsible for the color of the skin, mucous membranes, hair, and eyes.

Melatonin is a hormone produced by the brain.

It has antioxidant and immunomodulatory properties, so it is often called the elixir of health, which helps maintain youth, freshness of the skin, and beauty.

Numerous clinical trials have proven the benefits of taking melatonin for the treatment of various diseases, ranging from cardiovascular diseases to disorders of the gastrointestinal tract.

Dermatologist Sean Allen

The role of melatonin

The hormone affects the functioning of the biological clock and a person’s appearance. The body of an adult usually contains 3 mg of this substance; during the day its concentration decreases, increases in the evening, and reaches its maximum level at night.

This is because synthesis begins between 10:00 pm and 4:00 am. The hormone triggers restoration processes in the body, activates the immune system, neutralizes reactive oxygen species, protecting the body from premature aging and disturbances in the functioning of organs and systems.

The substance protects against stress and promotes rapid sleep, so its role in the body is extremely important.

Why do many people experience melatonin deficiency?

In the rhythm of modern city life, every second person has problems falling asleep, quality, and duration of sleep.

To spend time with friends and favorite things after a productive day at work, sometimes you have to fall asleep after midnight. This disrupts the normal synthesis of the hormone, a deficiency develops, which is why a person stops feeling cheerful.

At the same time, the aging process of cells accelerates, which becomes a prerequisite for the development of various diseases and premature wrinkles.

But the full synthesis of this substance is hampered not only by untimely falling asleep, but also by increased lighting of the room during rest.

In order not to disrupt the synthesis of melatonin, it is recommended to sleep with the curtains closed, without nightlights, mobile devices and other light sources.

If work activity is associated with the second half of the day, then, if possible, lighting should be kept to a minimum.

Melatonin as a medicine

The properties of this hormone and its effect on the body make it possible to use it to treat various diseases. It is allowed to take medications with melatonin in small dosages to correct various conditions.

Very often the hormone is taken as a mild sleeping pill. But it doesn’t just help you sleep, its spectrum of action is much wider.

Dietary supplements are excellent helpers in the fight against the consequences of insufficient night rest: chronic fatigue, disruption of the nervous system, desynchronosis, depression, etc.

Some studies indicate the effectiveness of using this substance in the treatment of cardiac ischemia, high blood pressure, and stomach ulcers.

Taking the drug will benefit people after 40 years of age. The dietary supplement is taken in courses. You need to take 1-3 mg per day.

It is also suitable for use by those who regularly experience stressful situations or have a night work schedule. A course of melatonin will help normalize well-being for those who suffer from sleep deficiency.

Unfortunately, the synthesis of the substance decreases over the years, so many older people experience serious sleep problems. To compensate for the lack of the hormone, this substance is also recommended for older people.

There is no need to worry about the development of side effects if you follow the indicated dosage, duration of use, contraindications (diabetes mellitus, gestation period, breastfeeding, autoimmune diseases, epilepsy).

The substance does not cause addiction, nor does it reduce the synthesis of your own melanin.

Dermatological surgeon Jennifer Trent

In very rare cases, however, an individual reaction in the form of nausea, headache, and stomach discomfort is possible. In this case, it is recommended to either reduce the dosage or stop taking it altogether.

What foods contain melanin?

Over time and with age, the amount of pigment in the body may decrease. Therefore, a person may experience spots on the skin and gray hair. A harmonious and balanced diet, including healthy foods to increase melanin production, will help maintain health.

For the synthesis of melanin, it will be useful to maintain a healthy lifestyle, with walks in the fresh air, exposure to the sun for the optimal amount of time per day, and moderate physical activity. Let's talk in more detail about products that affect melanin production.

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Foods that support melanin production

:

  • Animal products

    . They contain copper and protein, which are necessary for the production of pigment.

  • Cereals, legumes and greens

    . Rich in vitamins A, E, B, which promotes better absorption of beneficial components from food.

  • Orange fruits and vegetables

    contain a large amount of carotene, which gives the fruit a rich color and also increases the amount of melanin produced.

  • And other groups of products that support melanin production, but in smaller quantities. For example, nuts, some fruits and vegetables, leafy crops

    .

Table of foods to support melanin production.

Category Name
Animal products Beef, dairy products (cheese, cottage cheese, milk), seafood (mussels, oysters, clams, lean fish, seaweed), turkey, offal (liver, kidneys)
Cereals, legumes, greens Sesame, pumpkin seeds, beans (soybeans, beans, lentils, peas, chickpeas), grain products and any types of cereals (mainly buckwheat, oatmeal, rolled oats), lettuce, spinach, celery, dill, parsley, green onions
Orange fruits and vegetables Pumpkin, carrot, apricot, melon, peach, persimmon, tangerine, orange
Nuts Peanuts, almonds, hazelnuts
Other fruits Bananas, avocados, coconuts
Other vegetables Cabbage, beets + leafy crops with dark shades

Melanin function (3 pluses)

Let's look at the beneficial functions of melanins to better understand what they are:

  1. Pigments support the barrier protective functions of the skin. They absorb ultraviolet light, bind cations, anions, chelate (capture, bind) pro-oxidant metal ions (manganese, chromium, copper, mercury, lead). When light is absorbed under the influence of this pigment, the energy is partially converted into heat and partially spent on photochemical reactions.
  2. In addition to optical protection, they inhibit the effects of free radical reactions in cells and have an antioxidant effect.
  3. Pigments are involved in eliminating the effects of stress and are an integral part of the immune system.
  4. They deactivate free radicals that are formed after irradiation with ionizing ultraviolet radiation.

But it also happens that melanins oxidize, polymerize, and produce free oxygen radicals that damage the cell, which causes premature aging of the skin (probably many have heard that with excessive exposure to the sun, the skin not only tans, but also ages faster).

Due to the pigment's ability to produce reactive oxygen species, it both protects and damages the skin when oversynthesized.

Rules for consuming foods containing melanin

As with other products, everything needs moderation. Any food in excess will not lead to anything good. Of primary importance, as always, will be the nutritional value and variety. Add foods from our table to your diet, experiment, but don’t forget about the rational basics of nutrition: nutritious meals, water regime, enough fiber, healthy fats, complete protein. Before getting the nutrients you need from supplements, unless you have serious deficiencies, try to get them by working on your diet.

How is melanin synthesized?

The synthesis of this pigment is extremely complex, depends on the interaction of many factors and is regulated by the action of melanocyte-stimulating hormones (α-MSH, β-MSH and γ-MSH) produced by the pituitary gland. Alpha-melanocyte-stimulating hormone has the most pronounced effect on the process of melanin formation.

Pigment synthesis occurs in the organelles of melanocytes - melanosomes. It begins with the oxidation of tyrosine (an amino acid). As a result of this reaction, the amino acid dihydroxyphenylalanine (DOPA) is formed as a precursor of adrenaline. Subsequently, the molecules of this amino acid are oxidized and, after a series of reactions, are converted into melanin.

The pigment accumulates in the cells of the epidermis, and its amount determines the shade of the skin, eye and hair color. Under the influence of ultraviolet rays, more of this pigment is synthesized in the lower layers of the skin, and it becomes tanned.

Reasons for increased melanin levels

Hyperpigmentation

- the process of oversaturation of certain areas of the skin with coloring pigment.

Causes

:

  • natural aging of the body;
  • hormonal changes as a result of menopause, pregnancy or taking hormonal medications;
  • liver dysfunction;
  • thyroid diseases.

Symptoms of excess melanin in the body

:

  • birthmarks

    – look like blurry spots of different diameters and shapes, colors – black, light beige, dark brown;

  • freckles

    – closely spaced small spots of dark and light brown tones.

  • dark spots

    – formed on clean skin or at sites of injury spontaneously or under the influence of external harmful factors, color – dark;

  • moles

    – a skin defect of an oval or round shape, the shade ranges from black to brown.

Question answer

When the sun's rays hit the skin, they begin to burn it. As a result, activation of free radicals is observed. The cell is literally destroyed. It is melanin that absorbs free radicals, which saves our cells.

If your tan is uneven, gray hair appears early, wrinkles appear, there are white spots on the skin surface, and you often have burns, then you should suspect a lack of melanin.

To do this, review your lifestyle, get rid of bad habits, eat healthy foods, and as prescribed by your doctor, you can start taking medications and dietary supplements.

What foods reduce melanin levels?

There are a number of products that, on the contrary, reduce pigment production. If such food is regularly present in the diet, the level of melanin decreases sharply. People who want a nice, even tan should avoid consuming these products while on holiday.

  • too salty crackers, which are consumed with beer, chips and peanuts, pickles and salty foods;
  • sweet pastries, cakes, pies, buns, ice cream, candies, marmalade, marshmallows, waffles and cookies;
  • alcohol, especially wine, martini, cognac, rum, aperitif, vodka and other alcoholic drinks;
  • carbonated drinks, strong coffee and tea;
  • boiled corn.

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Melanin pigment can be reduced through home treatments, in-clinic treatments and home remedies. Many people use kitchen ingredients to reduce melanin in the skin, but it's worth noting that there is no scientific evidence for these methods.

  • Potato

    Potatoes contain an enzyme called catecholase, which reduces the level of melanin in the skin. Potatoes are an excellent antioxidant that help the skin get rid of oxidative stress.

  • Lemon

    Lemon contains alpha hydroxy acid, which exfoliates the top layer of skin containing melanin. Lemon is a natural bleaching agent.

  • Tomatoes

    Tomatoes have many benefits for the skin. One of them is their ability to inhibit the enzyme tyrosinase, which helps in the synthesis of melanin. They also have anti-inflammatory and anti-aging properties.

However, you must understand that melanin depends not only on food, but also on genetics. It is impossible to change genetic factors, but a properly formulated diet can increase the concentration of melanin and, therefore, avoid the appearance of gray hair and age spots.

Foods that reduce melanin production

For pigment to be produced effectively, food should not include harmful products. Fried and smoked foods are strictly not recommended. You should not abuse food containing dyes, flavors, flavor enhancers and other additives.

If you want to get an even and healthy tan without risking a burn, do not include in your daily diet:

  • salted, fried and smoked;
  • sweets (especially chocolate);
  • coffee;
  • alcohol;
  • boiled corn.

Vitamin C reduces the production of melanin, but it effectively fights the effects of free radicals, so it cannot be excluded from the diet.

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