Pharmacodynamics and pharmacokinetics
The use of Iodomarin is indicated for the treatment and prevention of thyroid diseases.
Iodine is an indispensable, vital microelement for the human body, without which normal activity of the thyroid gland .
Its hormones regulate the functioning of the brain , heart , nervous and vascular systems , mammary glands , ovaries in women and testes in men, ensure the correct course of metabolic in the body (including proteins, carbohydrates and fats ), actively participate in energy metabolism, and are also responsible for the growth and normal development of the child.
The use of Iodomarin allows you to compensate for iodine deficiency when it is insufficiently supplied to the body through food, which is especially important in childhood, during periods of childbearing and breastfeeding, as well as for people who live in geochemical zones with iodine soil and water.
Iodine entering the body in physiological quantities makes it possible to normalize the size of the thyroid gland in children and young adults, as well as the ratio of thyroid hormones T3 and T4 and the level of thyroid-stimulating hormone .
After oral administration iodine is almost completely absorbed in the small intestine , after which within 2 hours it is distributed in the intercellular space and accumulates in the thyroid gland, salivary and mammary glands , kidneys, and stomach .
The concentration in blood plasma after using a p/os standard dose is from 10 to 50 ng/ml, while the concentration of iodine in breast milk, saliva and gastric juice is 30 times higher than its concentration in blood plasma .
The thyroid gland contains 75% of all iodine (from 10 to 20 mg).
Iodine from the body mainly through urine , and also, to a lesser extent, the lungs and intestinal .
Pharmacological properties
Pharmacodynamics
Iodine is a vital trace element that is a component of the thyroid hormones - thyroxine and triiodothyronine. Thyroid hormones are involved in the development of all organs and systems, in the regulation of metabolic processes in the body: they are responsible for the metabolism of proteins, fats, carbohydrates and energy in the body, regulate the activity of the brain, nervous and cardiovascular systems, reproductive and mammary glands, as well as growth and child development.
Iodine deficiency is especially dangerous for children, adolescents, pregnant and lactating women.
Pharmacokinetics
Suction
When taken orally, potassium iodide is almost completely absorbed in the small intestine.
Distribution
The average volume of distribution for healthy individuals is approximately 23 liters (38% of body weight). The normal plasma iodine concentration ranges from 0.1 to 0.5 μg/dL. Accumulates in the thyroid gland, salivary glands, mammary glands and stomach tissues. The concentration in saliva, gastric juice and breast milk is approximately 30 times higher than in blood plasma.
Removal
Excreted by the kidneys, the concentration of iodine in urine relative to creatinine (mcg/g) is an indicator of its intake into the body.
Indications for use
Indications for use of the drug:
- prevention of endemic goiter (associated with insufficient iodine content in the environment);
- prevention of goiter recurrence after completion of a course of conservative treatment with thyroid hormones or surgical removal;
- treatment of euthyroid (non-toxic diffuse) goiter by iodine deficiency in children, adolescents and adults under 40 years of age.
Contraindications
Contraindications to the use of Iodomarin are:
- hypersensitivity to iodine ;
- hyperthyroidism;
- senile (herpetiform) dermatitis.
In case of toxic thyroid adenoma (Plummer syndrome), nodular goiter , the use of the drug in doses exceeding 300 mcg per day is contraindicated. The exception is the need to prescribe iodine-induced thyroid blockade before surgery on this organ.
It is recommended to avoid prescribing the drug:
- during radioactive iodine ;
- patients who have been diagnosed with thyroid cancer , as well as if there is a suspicion of a cancerous tumor .
Can I take Iodomarin if I have hypothyroidism?
Iodomarin for hypothyroidism is prescribed only in cases where the latter has developed against the background of severe iodine deficiency.
special instructions
It should be taken into account that during drug therapy in patients with renal failure, hyperkalemia may develop.
Before starting therapy, it is necessary to exclude the presence of hyperthyroidism or nodular toxic goiter in the patient, as well as a history of these diseases.
If there is a predisposition to autoimmune thyroid diseases, the formation of antibodies to thyroid peroxidase is possible. Saturation of the thyroid gland with iodine can prevent the accumulation of radioactive iodine used for therapeutic or diagnostic purposes. In this regard, it is not recommended to take the drug before carrying out activities using radioactive iodine.
Side effects
Treatment of non-toxic diffuse goiter in newborn infants, children and adolescents, as well as the use of Iodomarin for preventive purposes (at any age), as a rule, does not provoke side effects.
In rare cases, against the background of long-term use of the drug, the development of iodism - aseptic inflammation of the skin and mucous membranes in places where iodine is released (in the area of the paranasal sinuses , salivary glands , respiratory tract ).
It manifests itself in the form of “cold” symptoms (lacrimation, conjunctivitis , runny nose , cough , “ iodine fever ”, etc.), bronchitis , the appearance of a metallic taste in the mouth and a characteristic odor from the mouth, increased salivation, urticaria , increased thirst, staining oral cavity, diarrhea , cramps , weakness, dizziness, soreness and burning sensation in the throat, a special skin rash (iododerma) and “iodine” acne. Vomit is yellow or blue.
, exfoliative dermatitis or Quincke's edema may develop .
When using the drug in a dose exceeding 150 mcg/day, latent (masked) hyperthyroidism often becomes manifest ( true hyperthyroidism ).
Long-term use of the drug at a dose exceeding 300 mcg/day can provoke iodine-induced thyrotoxicosis (the likelihood of its development is especially high in elderly patients who of goiter for a sufficiently long period of time; in the presence of Graves' disease or nodular goiter ).
Pharmacokinetics
Suction
When taken orally, potassium iodide is almost completely absorbed in the small intestine.
Distribution
The average volume of distribution for healthy individuals is approximately 23 L (38% of body weight). The normal plasma iodine concentration ranges from 0.1 to 0.5 μg/dL. Accumulates in the thyroid gland, salivary glands, mammary glands and stomach tissues. The concentration in saliva, gastric juice and breast milk is approximately 30 times higher than in blood plasma.
Removal
Excreted by the kidneys, the concentration of iodine in urine relative to creatinine (mcg/g) is an indicator of its intake into the body.
Instructions for Iodomarin (Method and dosage)
Instructions for use Iodomarin 100
To prevent goiter , Iodomarin for children under 12 years of age (including newborns) should be taken 1/2-1 tablet/day, the daily dose for patients over 12 years of age is 1-2 tablets/day.
During pregnancy and lactating women, it is recommended to take 2 tablets per day. Iodomarin 100 (200 mcg/day).
To prevent goiter recurrence, you should take 1-2 tablets per day.
Dosage regimen for euthyroid goiter :
- patients under 18 years of age (including newborn babies) - 1-2 tablets/day;
- adults under 40 years old - 3-5 tablets/day.
The tablets should be taken orally after meals with sufficient liquid. For children, the drug is pre-dissolved in milk or fruit juice.
For preventive purposes, it is recommended to drink Iodomarin for several years. If there are indications, the drug can be prescribed for life.
Treatment of goiter in newborn infants involves taking pills for 14-30 days; all other patients (children, adolescents and adults), as a rule, need to take the drug for six months to a year. In some cases, longer treatment may be required.
Instructions for use Yodomarin 200
To prevent iodine deficiency conditions and endemic goiter iodine entering the body of an adult does not exceed 150-200 mcg/day), you should take:
- ¼-½ tablet/day. (50-100 mcg/day) - children under 12 years of age (including newborn infants);
- ½-1 tablet/day. (100-200 mcg/day) - patients over 12 years of age;
- 1 tablet/day (200 mcg/day) - for pregnant women and during breastfeeding.
To prevent recurrence of iodine-deficient goiter after thyroidectomy , as well as after completing a course of therapy with thyroid hormones , both children and adults are prescribed to take 1-2 tablets daily.
Treatment of euthyroid goiter involves taking:
- from 100 to 200 mcg of iodine per day (½-1 tablet of Iodomarin 200) - for children;
- from 300 to 500 mcg of iodine per day (from 1 ½ to 2 ½ tablets) - for adults.
How to take Iodomarin 200?
It is recommended to take the tablets after meals. Take them with a sufficient amount of liquid, for example, a glass of water. Children under three years of age (including newborns) should first crush the tablets into powder before taking them.
Taking the drug for preventive purposes is usually recommended from several months to several years, often throughout life. Treatment of goiter in newborns usually takes from 2 to 4 weeks, in older children and adults - six months to a year or more.
In general, issues of dosing and duration of use of the drug for the prevention or treatment of thyroid diseases are decided individually by the attending physician.
Iodomarin 200 mcg No. 100 tab.
Instructions for medical use of the drug Iodomarin® 200 Trade name Iodomarin® 200 International nonproprietary name Potassium iodide Dosage form Tablets 200 mcg Composition One tablet contains the active substance - potassium iodide 0.262 mg (equivalent to iodine 0.200 mg), excipients: lactose monohydrate, magnesium carbonate basic light, gelatin, sodium carboxymethyl starch, type A, anhydrous silicon dioxide, magnesium stearate. Description Tablets are white to almost white in color, with a flat surface, with a bevel and a score on one side. Pharmacotherapeutic group Drugs for the treatment of thyroid diseases. Iodine preparations. ATC code H03CA Pharmacological properties Pharmacokinetics Typically, iodine enters the body through the gastrointestinal tract, but can also enter through the skin and from body cavities. This must be especially taken into account in case of erroneous medicinal administration of iodine. When taken orally, it is quickly absorbed from the gastrointestinal tract. Widely distributed in all tissues and fluids of the body. Inorganic iodine is absorbed in the small intestine almost 100%, and through the skin - insignificantly and uncontrollably. The volume of distribution in healthy people averages about 23 liters (38% of body weight). Serum inorganic iodine levels are usually between 0.1 and 0.5 μg/dL. In the body, iodide accumulates in the thyroid gland and other tissues such as the salivary glands, mammary glands and stomach. In saliva, gastric juice and milk, the concentration of iodide is 30 times higher than its concentration in blood plasma. Urinary iodine excretion, most often indicated in mcg/g creatinine, serves as a criterion for iodine supply, since in a balanced state it correlates with the daily iodine intake from food. Pharmacodynamics The effects that exogenously administered iodine has on the human body depend on the amount of iodine taken per day, on the type of iodine-containing drug, as well as on the condition of the thyroid gland (healthy organ, latent or manifest disease). As an element involved in the synthesis of thyroid hormones - thyroxine and triiodothyronine - iodine is an essential component of food. The need for it, that is, the amount of iodine that must be supplied to the body daily in order to prevent the development of endemic goiter, is about 100 - 150 mcg per day. The WHO recommended amount of iodine that should be consumed daily is 150 - 300 mcg. After iodine is absorbed by electrochemical means (iodination), oxidation occurs in the epithelial cells of the thyroid follicles with hydrogen peroxide (H2O2), which is a cosubstrate, catalyzed by the enzyme iodide peroxidase, from which elemental iodine is released. In this case, part of the tyrosine groups of the glucoprotein (thyroglobulin) is iodinated in positions 3 and, partially, 5 of the aromatic ring (iodization). As a result of oxidative condensation, the iodinated groups of tyrosine are combined to form the thyronine framework. The main products are thyroxine (T4) and triiodothyronine (T3). The “thyronine-thyroglobulin” complex formed in this way is released as a depot form of the thyroid hormone into the colloid of its follicle. Physiological amounts of iodine (up to 300 mcg) prevent the formation of goiter, which develops as a result of iodine deficiency, help normalize the size of the thyroid gland in newborns, children and adolescents, and also affect a number of disturbed biochemical parameters (T3/T4 ratio, TSH level). Indications for use - prevention of iodine deficiency (for example, for the prevention of endemic goiter and after resection of goiter caused by iodine deficiency) - treatment of diffuse euthyroid goiter caused by iodine deficiency in children, including infants, adolescents and young adults. Method of administration and doses Prevention of iodine deficiency diseases (in cases of insufficient intake of alimentary iodine into the body, amounting to at least 150-300 mcg per day): Infants, children 2 - 12 years old - ½ tablet per day Yodomarin® 200 (which corresponds to up to 100 mcg of iodine) Children from 12 years and adults - from ½ to 1 tablet of Iodomarin® 200 (which corresponds to 100 - 200 mcg of iodine) per day Pregnant and lactating: 1 tablet of Iodomarin® 200 (which corresponds to 200 mcg of iodine) per day Prevention of relapses after surgery for euthyroidism goiter or its drug treatment: ½ to 1 tablet of Iodomarin® 200 once a day (which corresponds to 100-200 mcg of iodine). Treatment of euthyroid goiter: Newborns, children and adolescents - from ½ to 1 tablet of Iodomarin® 200 mcg (which corresponds to 100-200 mcg of iodine) per day Adults at a young age - from 1 ½ to 2 ½ tablets of Iodomarin® 200 (which corresponds to 300- 500 mcg of iodine) per day Prophylactic administration of Yodomarin® 200 should usually be carried out for several years, often throughout life. For the treatment of goiter in newborns, in most cases, 2-4 weeks are sufficient; in children, adolescents and adults it usually takes 6-12 months or more. The duration of use of the drug is determined by the attending physician under the control of the level of iodine in the blood. The drug is taken after meals with a sufficient amount of liquid. For children, including newborns, it is recommended to first grind the drug and dissolve it in a small amount of milk or water. Side effects Very rarely - in the presence of larger autonomous areas in the thyroid gland and with daily doses of more than 150 mcg of iodine, hyperthyroidism can develop into a manifest form - when using the drug in a dose exceeding 300-1000 mcg of iodine per day, the development of hyperthyroidism is possible ( especially in elderly patients suffering from goiter for a long time, in the presence of nodular or diffuse toxic goiter) Contraindications - hypersensitivity to the active substance or one of the other components of the drug - manifest hyperthyroidism - latent hyperthyroidism in doses exceeding 150 mcg of iodine per day - toxic adenoma thyroid gland, nodular goiter (when used in doses from 300 to 1000 mcg/day), with the exception of preoperative iodine therapy for the purpose of blocking the thyroid gland according to Plummer) Drug interactions Iodine deficiency increases, and iodine excess decreases the response to hyperthyroidism therapy with thyroid drugs; In this regard, before or during treatment for hyperthyroidism, it is recommended to avoid, if possible, any iodine intake. Thyrostatic drugs, for their part, inhibit the transition of iodine to an organic compound in the thyroid gland and, thus, can cause the formation of goiter. The absorption of iodine by the thyroid gland is competitively suppressed by substances, the introduction of which into the thyroid gland occurs through the same “capture” mechanism as the introduction of iodide (for example, perchlorate, which, in addition, inhibits the recirculation of iodine in the thyroid gland), as well as substances that themselves are not transported by themselves, such as thiocyanate in concentrations exceeding 5 mg/dL. The absorption of iodine by the thyroid gland and its metabolism in it are stimulated by endogenous and exogenous thyroid-stimulating hormone (TSH). Simultaneous treatment with high doses of iodine, which suppress the secretion of thyroid hormones, and lithium salts can contribute to the occurrence of goiter and hypothyroidism. Higher doses of potassium iodide in combination with potassium-sparing diuretics may lead to hyperkalemia. Special instructions The drug Yodomarin® 200 contains lactose. Patients suffering from congenital galactose intolerance, lactase deficiency in the body, or glucose-galactose malabsorption syndrome should not take Yodomarin ® 200. Pregnancy and lactation During pregnancy and lactation, the need for iodine increases, so it is especially important to have a sufficient (200 mcg per day) intake of iodine in the body. Due to the diaplacental transition of iodine and the sensitivity of the fetus to pharmacologically active doses, iodine is not recommended to be prescribed in the milligram dose range. This also applies to the lactation period, since the concentration of iodide in milk is 30 times higher than in blood serum. An exception is high-dose iodine prophylaxis carried out after accidents in the field of nuclear technology. Features of the drug's influence on the ability to drive a vehicle or potentially dangerous machinery There are no indications that Yodomarin® 200 limits the ability to participate in street traffic, operate machines, or work without safety nets. Overdose Symptoms: Brown staining of the mucous membranes, reflex vomiting (if starch-containing components are present in food, the vomit becomes blue), abdominal pain and diarrhea (possibly bloody). Dehydration and shock may develop. In rare cases, esophageal stenosis has occurred. Fatal outcomes were observed only after taking large amounts of iodine (from 30 to 250 ml of iodine tincture). Long-term overdose in rare cases leads to the appearance of a phenomenon called iodism: a metallic taste in the mouth, swelling and inflammation of the mucous membranes (runny nose, conjunctivitis, gastroenteritis, bronchitis). Latent inflammations, such as tuberculosis, can be activated under the influence of iodide. The development of edema, erythema, acne-like and bullous rashes, hemorrhages, fever and nervous excitability occurs. Treatment: a) Therapy for acute intoxication: Gastric lavage with a solution of starch, protein or 5% sodium thiosulfate solution until all traces of iodine are removed. Symptomatic treatment of water and electrolyte imbalances, anti-shock therapy. b) Therapy for chronic intoxication Iodine withdrawal. c) Hypothyroidism induced by iodine Abolition of iodine, normalization of metabolism with the help of thyroid hormones. d) Iodine-induced hyperthyroidism This is not an overdose in the literal sense, because hyperthyroidism can also be caused by amounts of iodine that are physiological in other countries. Treatment in accordance with the form of the course: mild forms, under certain conditions, do not require treatment; in severe forms, thyreostatic therapy is required (the effectiveness of which, however, always appears with a delay). In the most severe cases (thyrotoxic crisis), intensive therapy, plasmapheresis or thyroidectomy are necessary. Release form and packaging 25 tablets are placed in a blister pack made of opaque, rigid polyvinyl chloride (PVC) film (250 microns) and rigid aluminum foil (20 microns). 1, 2 or 4 contour packages together with instructions for medical use in the state and Russian languages are placed in a cardboard pack. Storage conditions Store in a dry place, protected from light, at a temperature not exceeding 25°C. Keep out of the reach of children! Shelf life: 3 years After the expiration of the shelf life, the medicine cannot be used. Conditions for dispensing from pharmacies Without a prescription Manufacturer Berlin-Chemie AG (Menarini Group), Germany Registration certificate holder BERLIN-CHEMIE AG (MENARINI GROUP) Glienikker Weg 125 12489 Berlin, Germany Address of the organization that accepts claims from consumers regarding product quality in the territory of the Republic of Kazakhstan (product): Representative office of JSC Berlin-Chemie AG in the Republic of Kazakhstan Phone number: +7 727 2446183, 2446184, 2446183 fax number: +7 727 2446180 email address
Overdose
Symptoms of an overdose of Iodomarin are:
- reflex vomiting (in this case, the vomit is blue in color, which is due to the presence of starch-containing components in food);
- brown staining of mucous membranes;
- diarrhea (possibly melena, i.e. black, tarry stool);
- stomach ache.
In particularly severe cases, dehydration and shock may occur. of esophageal stenosis and the occurrence of the phenomenon of “iodism” have also been recorded
In case of acute intoxication, the patient is indicated for gastric lavage with a starch solution, a solution of five percent Sodium thiosulfate or protein (up to the removal of all traces of iodine), anti-shock therapy, and the prescription of symptomatic treatment to correct the disturbed water-electrolyte balance.
In case of chronic intoxication, you should stop taking the drug.
In case of iodine-induced hypothyroidism, you should stop taking Iodomarin. Treatment in this case is aimed at normalizing metabolism by prescribing thyroid hormones .
mild iodine-induced thyrotoxicosis develops while using the drug thyreostatic therapy is necessary (it should be remembered that its effect is always delayed).
In case of thyrotoxic crisis, intensive therapy, plasmacytopheresis procedures or removal of the thyroid gland .
Overdose of the drug Iodomarin, symptoms and treatment
Symptoms of acute poisoning: brown staining of the mucous membranes, vomiting (if starch-containing components are present in food, the vomit turns blue), abdominal pain and diarrhea (even bloody diarrhea is possible). Dehydration and shock may occur. In rare cases, the development of esophageal stenosis has been noted. Deaths were recorded only after the use of iodine in high doses - from 30 to 250 ml of iodine tincture. There is a report of the development of acute nephritis after simultaneous administration of potassium iodide solution and mefenamic acid tablets. Long-term use can cause the development of the phenomenon of iodism: a metallic taste in the mouth, swelling and inflammation of the mucous membranes (rhinitis, conjunctivitis, gastroenteritis, bronchitis). Latent processes, such as tuberculosis, can be activated under the influence of iodine. The development of peripheral edema, erythema, acne-like and bullous rash, hemorrhage, fever and nervous agitation is possible. Treatment of acute intoxication: gastric lavage with starch, protein or 5% sodium thiosulfate solution until traces of iodine disappear. Carrying out symptomatic therapy to eliminate disturbances in water and electrolyte balance, and, if necessary, anti-shock therapy. Treatment for chronic intoxication: discontinuation of iodine-containing drugs. Iodine-induced hyperthyroidism: This is not an overdose in the literal sense, since hyperthyroidism can also arise from an amount of iodine that is considered physiological in other countries. Mild forms do not require therapy, while severe forms require thyreostatic treatment, the effectiveness of which is delayed over time. In severe cases (thyrotoxic crisis), intensive therapy, plasmapheresis or thyroidectomy are necessary.
Interaction
Excessive iodine content reduces, and insufficient iodine increases the effectiveness of treatment of hyperthyroidism with thyreostatic drugs . In connection with this, before taking these medications, as well as during the treatment of hyperthyroidism , you should, if possible, avoid taking iodine in any form.
On the other hand, thyreostatic drugs inhibit the transformation of iodine into an organic compound in the thyroid gland and, therefore, can cause the development of goiter .
Combination therapy using high doses of iodine and drugs containing lithium salts can provoke hypothyroidism and the development of goiter .
Iodomarin in high doses in combination with potassium-sparing diuretics can cause hyperkalemia .
Analogues of Iodomarin
Level 4 ATC code matches:
Blue Yod
Potassium iodide
Synonyms of Iodomarin 100 are: Antisturmin , children's Iodine Vitrum , Iodide 100 , Iodine Vitrum 100 mcg , Iodandin 100 mcg , Iodbalance 100 mcg , Microiodide 100 , Potassium iodide Renewal 100 mcg .
Structural analogues of Iodomarin 200: 9 months Potassium iodide , Iodine Vitrum 100 mcg , Iodine Vitrum 200 mcg , Iodantine 200 mcg , Iodine balance 200 mcg , Microiodide 200 , Potassium iodide Renewal 200 mcg .
Iodine balance or Iodomarin - which is better?
Iodbalance and Iodomarin are generic drugs. Having analyzed why they are prescribed, how to take both drugs, the range of contraindications, as well as possible drug interactions, we can conclude that the only difference between the drugs is a slight difference in price ( Iodine balance is slightly cheaper than its analogue).
Composition per tablet:
Active substance:
potassium iodide - 0.262 mg (corresponding to 0.2 mg of iodine).
Excipients:
lactose monohydrate, magnesium hydroxycarbonate, gelatin, sodium carboxymethyl starch, colloidal silicon dioxide, magnesium stearate.
Description: round flat-cylindrical tablets of white or almost white color with a chamfer and a score on one side.
Pharmacotherapeutic group: thyroxine synthesis regulator - iodine drug
ATX code: H03CA
Iodomarin during pregnancy and breastfeeding
Pregnant women and lactation have an increased need for iodine .
In the 1st trimester, when the formation and formation of the child’s main organs and systems occurs, insufficient supply of this microelement can cause changes in the mother’s hormonal levels and, consequently, disturbances in the formation of the fetus (primarily the child’s brain ).
In children who did not receive enough iodine during prenatal development, pathologies of the development of the nervous system , problems with the thyroid gland (up to the appearance of neoplasms), mental defects and mental retardation .
In the early stages of pregnancy, the fetus does not have thyroid gland hormones . Therefore, in order to avoid problems after conception, doctors recommend starting to take iodine supplements when planning a pregnancy (optimally within six months, so that the body is well prepared for bearing a child).
Also, iodine can trigger the launch of a protective mechanism: perceiving pregnancy as an additional burden, the mother’s body will do its best to get rid of it. In particularly severe cases, miscarriage often occurs.
When using Iodomarin for pregnant and lactating women, it should be remembered that potassium iodide has the ability to penetrate the placenta and into breast milk. Therefore, the drug should be taken strictly in recommended doses.
The dosage during pregnancy is usually the following - 200 mcg/day: Iodomarin 200 during pregnancy is prescribed to take 1 tablet per day, Iodomarin 100 - 2 tablets per day.
Special instructions for the use of the drug Iodomarin
The drug contains lactose, so it should not be used in cases of congenital galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome. Use during pregnancy and lactation. During pregnancy and lactation, the need for iodine is increased, so a sufficient intake of iodine in the body (200 mcg/day) is especially important. Due to the penetration of iodine through the placental barrier and the sensitivity of the fetus to it, the recommended doses should not be exceeded. This requirement also applies to the period of breastfeeding, since the concentration of iodine in milk is 30 times higher than that in blood plasma. An exception is high-dose iodine prophylaxis, which is carried out in case of man-made radioactive contamination. Use in children. The drug can be used in children at any age if indicated. The ability to influence reaction speed when driving vehicles or operating machinery. There is no data on negative effects.
Reviews about Yodomarin
Reviews for Iodomarin 100, like reviews for Iodomarin 200, are mostly positive. Using the drug for medicinal purposes can reduce the symptoms of the disease; when taking the tablets for preventive purposes, many people note a decrease in irritability, an improvement in general well-being and memory, and an increase in concentration.
There are no less good reviews for Iodomarin during pregnancy. In women, the use of this remedy helps prevent the development of iodine deficiency conditions and associated diseases, normalize the metabolism of proteins , lipids and carbohydrates , and ensure normal activity of the brain and cardiovascular system .
iodine intake is the key to normal physical and mental development.
In some reviews, people write that taking Iodomarin helped them bring their weight to normal levels. So, can the drug be used for weight loss? Endocrinologists answer that it is possible, but only according to the doctor’s indications.
In a number of situations, excess weight is a consequence of decreased thyroid function , and then it is impossible to lose it either with the help of diets or with the help of physical activity.
The manufacturer does not recommend taking Iodomarin for hypothyroidism , excluding, however, those cases where the disease is associated with obvious iodine .
It should be remembered that is responsible of the secretion of thyroid hormones , but the hypothalamic hormones, which, in turn, are controlled by the cerebral cortex, are responsible for regulating the influence of the pituitary gland on the thyroid gland .
Thyroid hormones also influence the pituitary gland , hypothalamus , a number of endocrine glands , the course of metabolic processes, and the condition of internal organs and their systems.
Thus, uncontrolled use of Iodomarin for the purpose of losing weight can provoke serious disturbances in the usual rhythm of thyroid activity and, as a consequence, the entire endocrine system of the body with all the ensuing consequences.
To gently stimulate thyroid function and activate metabolic processes, it is recommended to first review your diet, supplementing it with foods high in iodine (seafood, onions, garlic, eggplants, beets, radishes, persimmons, grapefruits, etc.), or at least replacing regular iodized salt.
Iodomarin is used as a dietary supplement. You can take it for weight loss only after consulting a doctor and not exceeding the recommended dose.
Iodomarin price, where to buy
The price of Iodomarin 100 in Russian pharmacies is about 145 rubles for package No. 100, the price of Iodomarin 200 is about 215 rubles for package No. 100 and about 135 rubles for package No. 50.
How much does Yodomarin cost in Ukraine?
You can buy Iodomarin 100 No. 100 for an average of 70-77 UAH, the cost of Iodomarin 200 is from 58 UAH (for package No. 50)
- Online pharmacies in RussiaRussia
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ZdravCity
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Pharmacy Dialogue
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