The action of nootropic drugs is aimed at improving cognitive abilities and brain functioning in general. Cereton belongs to this group of drugs. The drug provides metabolic protection and promotes the release of choline. This allows you to improve concentration, memory, and improve learning abilities. Against the background of the drug’s action, restoration processes are launched during the development of various pathologies.
Compound
Capsules | 1 caps. |
active substance: | |
choline alfoscerate (calculated as 100% substance) | 400 mg |
excipients: glycerol - 50 mg; purified water - up to 590 mg | |
capsule: gelatin; sorbitol; glycerol; methyl parahydroxybenzoate; propyl parahydroxybenzoate; titanium dioxide; iron oxide yellow dye; purified water |
Release form and composition
Cereton is produced in the form of gelatin capsules and solution for injection. The active substance in the drug is choline alfoscerate. Its content in capsules is 400 mg, in ampoules of 4 ml – 1000 mg.
The capsules are oval in shape and yellowish-brown in color. They are filled with an oily liquid. Auxiliary components used in the manufacture of capsules are glycerol and purified water. The capsule shell is made on the basis of gelatin using other additional components that allow it to be given the desired shape.
Pharmacodynamics
Nootropic drug. Central anticholinergic stimulant, which contains 40.5% metabolically protected choline. Metabolic protection promotes the release of choline in the brain. Provides the synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances metabolic processes in the central nervous system, activates the reticular formation. Increases the linear speed of blood flow on the side of the traumatic brain injury, promotes the normalization of the spatio-temporal characteristics of spontaneous bioelectrical activity of the brain, regression of focal neurological symptoms and restoration of consciousness; has a positive effect on the cognitive and behavioral reactions of patients with vascular diseases of the brain (dyscirculatory encephalopathy and residual effects of cerebrovascular accident). It has a preventive and corrective effect on the pathogenetic factors of involutional psychoorganic syndrome, changes the phospholipid composition of neuron membranes; participates in the synthesis of phosphatidylcholine (membrane phospholipid); improves the plasticity of neuronal membranes. Stimulates the dose-dependent release of acetylcholine under physiological conditions, improves synaptic transmission and receptor function. Does not affect the reproductive cycle and does not have a teratogenic or mutagenic effect.
Contraindications and negative reactions of the body
The main contraindications to taking the drug are hypersensitivity to the active ingredient and other components. The medicine is not prescribed before reaching the age of 18 years, as well as during pregnancy and lactation.
Contraindications include the acute stage of hemorrhagic stroke, which, as a rule, develops against the background of high blood pressure.
When taking the drug, allergic reactions may occur: rash and itching on the skin. Other adverse reactions are rare. Nausea is sometimes observed after taking the drug, which is a consequence of the effect of the drug on the peripheral nervous system. When it appears, discontinuation of the drug is not required; it is enough to reduce the dosage.
It is necessary to consult a doctor when the medicine provokes disturbances in the functioning of the central nervous system. For example, during treatment, headaches, sleep problems, and increased excitability occur. It may also be necessary to discontinue the drug if gastritis and peptic ulcers worsen during oral administration, or severe constipation or diarrhea occurs.
Indications for Cereton®
recovery period of severe traumatic brain injury and ischemic stroke, recovery period of hemorrhagic stroke, occurring with focal hemispheric symptoms or symptoms of brain stem damage;
psychoorganic syndrome against the background of degenerative and involutional changes in the brain;
cognitive disorders (impaired thinking function, memory, confusion, disorientation, decreased motivation, initiative and ability to concentrate), incl. for dementia and encephalopathy;
senile pseudomelancholia.
Terms of use
Cereton injections are prescribed for acute conditions. In this case, deep intramuscular injection is performed. The solution can also be administered intravenously. Therapeutic dose is 1 ampoule, which corresponds to 1000 mg of the active substance. Duration of use is 10-15 days. Thus, the price of the medicine for one course is quite high.
Cereton tablets are mainly used during the recovery period after traumatic brain injuries and strokes. The duration of treatment with the drug is 6 months. Recommended dose of medication:
- In the morning, 2 capsules, which corresponds to 800 mg.
- During the day, 1 capsule, which corresponds to 400 g of active substance.
For symptoms of dementia and confirmation of circulatory problems in the brain, it is recommended to take 1 capsule three times a day. Treatment lasts 3-6 months.
Manufacturer
JSC NPO "Europe-Biopharm". 400078, Volgograd, st. 2nd Gornaya, 4.
JSC "Pharm" 141345, Russia, Moscow region, Sergiev Posad municipal district, rural settlement Bereznyakovskoye, pos. Belikovo, 11.
Tel/fax: 956-29-30;
or
Artlife LLC. 634034, Tomsk, st. Nakhimova, 8/2.
Owner of the registration certificate: CJSC Pharm.
JSC "Pharm" 141345, Russia, Moscow region, Sergiev Posad municipal district, rural settlement Bereznyakovskoye, pos. Belikovo, 11.
Tel/fax: 956-29-30.
Owner of the registration certificate: CJSC Pharm.
Consumer complaints should be sent to the address of JSC “Pharm.
Special instructions and reviews
There are no data on interactions with other drugs. There is no effect on psychomotor functions, so there are no restrictions on driving a car or performing any operations requiring precision.
You can find both positive and negative reviews about the drug. Many patients emphasize that after the course of treatment, memory and concentration have significantly improved. Many also note a positive effect associated with slowing the progression of dementia.
All negative reviews, as a rule, contain information that there is no positive result. Negative side reactions of the body are also often observed, due to which it was necessary to abandon the medicine.
Indications for use of Cereton
- senile pseudomelancholia;
- cognitive impairment;
- attention disorder;
- dementia of unknown origin;
- encephalopathy of unspecified origin;
- cerebral infarction ;
- apathy;
- after ONMC ;
- encephalopathy;
- organic mental disorders;
- behavioral disorders of organic origin (with central nervous system dysfunction);
- senile dementia;
- lack of initiative, decreased motivation;
- lack of coordination;
- after intracranial hemorrhages;
- after brain injuries.
Additional indications for the use of Cereton in elderly people:
- psychoorganic syndrome,
- cerebrovascular insufficiency,
- multi-infarct dementia.
Cereton price, where to buy
The cost of Cereton solution is 3 ampoules - about 350 rubles, 5 ampoules - about 550 rubles. The price of Cereton in capsules is about 1000 rubles per pack of 28 pieces. In different regions, the price of Cereton varies depending on the pharmacy chain.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Cereton solution for intravenous and intramuscular injection.
250 mg/ml 4 ml 5 pcs. CJSC “Pharm” 549 rub. order - Cereton capsules 400 mg 28 pcs. Artlife LLC Artlife/Sotex
RUB 1,091 order
- Cereton capsules 400 mg 56 pcs. Artlife/Sotex LLC
RUB 1,589 order
- Cereton capsules 400 mg 14 pcs. Artlife/Sotex LLC
RUR 585 order
Pharmacy Dialogue
- Cereton (caps. 400 mg No. 56) Artlife LLC/PharmFirma Sotex CJSC
RUB 1,543 order
- Cereton (caps. 400 mg No. 14) Artlife LLC/PharmFirma Sotex CJSC
RUR 538 order
- Cereton (amp. 250 mg/ml 4 ml No. 3) Sotex
RUR 358 order
- Cereton (caps. 400 mg No. 28) Artlife LLC/PharmFirma Sotex CJSC
RUB 1,059 order
- Cereton (amp. 250 mg/ml 4 ml No. 5) Sotex
RUR 578 order
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Analogues of Cereton
Level 4 ATC code matches:
Delecite
Choline alphoscerate
Cerepro
Gliatilin
Coincidence in pharmacological effects:
- Mexidol
- Actovegin
Structural analogues of Cereton:
- Gliatilin
- Cerepro
Side effects
Skin:
- hives;
- rashes.
Digestive tract:
- ulcerative lesions of the stomach;
- constipation;
- gastritis;
- pharyngitis;
- dry mouth mucous membranes.
Nervous system:
- dizziness;
- hyperkinesis;
- convulsive syndrome;
- nervousness;
- anxiety;
- aggression;
- drowsiness;
- migraine;
- ischemic changes in brain tissue.
Rarely, urinary disturbances, diarrhea syndrome , and pain in the injection area are recorded.