What to choose Gendevit, Undevit Revit or Hexavit?

Main indicators of Gendevit

Gendevit is a low-cost multivitamin complex. The price is 60-70 rubles. Due to the active components, the pharmacological effect is ensured:

• thiamine - improves nervous system function;
• riboflavin - normalization of the activity of the organs of vision, cellular respiration;
• pyridoxine - influence on the synthesis of amino acids, neurotransmitters;
• cyanocobalamin - restores the epidermis, normalizes hematopoiesis, stimulates the formation of folic acid;
• ascorbic acid - improves the function of the immune system, strengthens teeth, bones, cartilage;
• nicotinamide - normalization of metabolism;
• folic acid - improves metabolism, stimulates erythropoiesis, stimulates the development of the nervous system in the fetus;

• tocopherol - eliminates the action of free radicals;
• calcium pantothenate - ensuring tissue regeneration.

The medicine is indicated for use for the prevention and treatment of hypovitaminosis. It is mainly prescribed during pregnancy and lactation, as it contains folic acid. The only side effects include allergic reactions. The drug is contraindicated in case of individual intolerance.

It is not recommended to exceed the dose. If you combine the product with other multivitamin complexes, hypervitaminosis will appear. This will worsen the patient’s well-being and increase the risk of an allergic reaction.

Analogues and important instructions

Among the analogues are a number of inexpensive vitamin complexes that are sold in any pharmacy:

It is forbidden to take other multivitamins at the same time as Undevit - this increases the risk of overdose. Do not be alarmed if your urine turns dark yellow or bright yellow during treatment - this is a consequence of taking riboflavin. Vitamin A can reduce the effect of glucocorticosteroids, which must be taken into account when treating the latter. Iron-containing preparations inhibit the effect of vitamin E, and ascorbic acid reduces the effectiveness of heparin treatment.

When to drink Undevit?

Undevit is a low-cost multivitamin. It is 40-50 rubles. The set contains 50 tablets. The pharmacological effect is provided by the components contained. The use of vitamins B, C, E, A, P is combined. The quantitative ratio is selected in such a way as to bring maximum benefit to the body. The drug contains the following beneficial substances:

• tocopherol;
• ascorbic acid;

• calcium;
• nicotinamide;
• pyridoxine;
• retinol, riboflavin, rutoside;
• folic acid, cyanocobalamin;
• thiamine

The drug is indicated for use in cases of hypovitaminosis, deterioration of metabolism, after a decrease in the function of the immune system against the background of a previous illness. It is recommended to use it after the use of antibiotics, when there is a strong effect on the gastrointestinal tract with deterioration in the absorption of substances.

The only contraindication for use is individual intolerance, accompanied by the development of allergic reactions.

The drug can cause a negative effect on the human body if high dosages are used during inflammatory lesions of the liver, gastric and duodenal ulcers.

The use of a multivitamin complex is allowed, but in limited quantities. During this period, it is recommended to give urine for OAM, a biochemical test, to monitor the condition of the organs.

Undevit-KV dragee No. 50

Name

Undevit-KV others in containers (bans) No. 50 in pack No. 1

Release form

Dragee

pharmachologic effect

Pharmacodynamics

Multivitamin medicine. Refers to drugs that regulate metabolic processes. Normalizes metabolism, including during the aging process. The pharmacological effect of the drug is determined by the active substances included in its composition. Vitamin A (retinol) plays a key role in the synthesis of enzyme proteins and structural components of tissues, is necessary for the formation of epithelial cells, bones and the synthesis of rhodopsin (visual pigment), supports the division of immunocompetent cells, the normal synthesis of immunoglobulins and other factors of protection against infections. Vitamin E (α-tocopherol acetate) is a fat-soluble vitamin that exhibits high antioxidant and radioprotective effects, protects cell membranes from damage by free radicals, takes part in the biosynthesis of heme and proteins, cell proliferation and other important processes of cellular metabolism. Vitamin E improves oxygen consumption by tissues. Shows angioprotective effect, affecting the tone and permeability of blood vessels, stimulating the formation of new capillaries. Vitamin B1 (thiamine hydrochloride) is an important coenzyme in the metabolism of carbohydrates and takes part in the functioning of the nervous system. Vitamin B2 (riboflavin) is an important catalyst for the processes of cellular respiration and visual perception. Vitamin B6 (pyridoxine hydrochloride) as a coenzyme takes part in protein metabolism and the synthesis of neurotransmitters. Vitamin B12 (cyanocobalamin) is a growth factor, necessary for the normal course of hematopoiesis and red blood cell maturation, and takes part in the synthesis of amino acids, nucleic acids and myelin. Vitamin C (ascorbic acid) takes part in the redox processes of the body, the synthesis of hemoglobin, affects the metabolism of amino acids, accelerates the absorption of iron from the gastrointestinal tract, increases the nonspecific resistance of the body, is necessary for the growth and formation of bones, skin, teeth and for normal functioning of the nervous and immune systems. Vitamin PP (nicotinamide) takes part in the processes of tissue respiration, carbohydrate and lipid metabolism. Folic acid stimulates erythropoiesis and takes part in the synthesis of amino acids and nucleic acids. Rutin normalizes capillary permeability, strengthens vascular walls, reduces platelet aggregation, exhibits antioxidant properties, prevents oxidation and promotes the deposition of ascorbic acid in tissues. Calcium pantothenate is part of coenzyme A and is necessary for the normal formation of the tricarboxylic acid cycle, the synthesis of ATP (adenosine triphosphate), the production of hormones and antibodies, the synthesis of acetylcholine, and the absorption of potassium ions, glucose, and vitamin E from the intestines.

Pharmacokinetics

After oral administration, the drug is well absorbed from the small intestine into the systemic circulation and penetrates into all organs and tissues. Clinical characteristics.

Indications for use

As a preventive and therapeutic agent for improving metabolic processes and general condition in people of working age and the elderly, including premature aging, asthenic syndrome, as well as during the period of convalescence after infectious diseases, in the postoperative period, after long-term therapy with broad-spectrum antibiotics.

Directions for use and doses

The drug is prescribed to adults and children over 14 years of age orally, after meals: for prophylactic purposes - 1 tablet 2 times a day, for treatment - 2 tablets 3 times a day for 20-30 days. Repeated courses should be carried out after 1–3 months. During pregnancy, to prevent the risk of a teratogenic effect, the daily dose of the drug should not exceed 1 tablet per day. The course of treatment depends on the severity and course of the disease and is determined by the doctor individually. Children. The use of the drug is contraindicated for children under 14 years of age.

Use during pregnancy and lactation

Use during pregnancy or breastfeeding is possible only taking into account the benefit to the mother over the potential risk to the fetus/child. During pregnancy, to prevent the risk of a teratogenic effect, the daily dose of the drug should not exceed 1 tablet per day. The dose of vitamin A should not exceed 5,000 IU for pregnant women and women planning to become pregnant. Large doses of retinol (over 10,000 IU) should not be used by women during breastfeeding due to the risk of developing hypervitaminosis A in infants.

Precautionary measures

When using the drug, it is necessary to observe the dosage and duration of the course of use. The drug should be used with caution in patients with diabetes mellitus, degenerative heart diseases, cardiac decompensation and coronary heart disease, diseases of the hematopoietic organs, impaired iron metabolism (hemosiderosis, hemochromatosis, thalassemia), gastrointestinal diseases, peptic ulcers. and duodenum in history, cholelithiasis, chronic pancreatitis, liver damage, patients with acute nephritis, urolithiasis, glaucoma, hemorrhages, moderate arterial hypotension. When using the drug, monitoring of blood pressure and kidney condition is necessary. Use with caution in patients with neoplasms (except for cases accompanied by megaloblastic anemia). It should be taken into account that the use of ascorbic acid in high doses may change some laboratory parameters (blood glucose, transaminases, uric acid, creatinine). The simultaneous use of ascorbic acid with an alkaline drink reduces its absorption, so you should not drink the drug with alkaline mineral water. Do not use the medicine with hot drinks (especially coffee), alcohol. It is not recommended to use the drug at the end of the day, since ascorbic acid has a slight stimulating effect. Do not exceed the recommended dose. When using the drug, like other multivitamin preparations, you need a complete protein diet that promotes better absorption and metabolism of vitamins, especially water-soluble ones. Women who have used high doses of retinol (more than 10,000 IU) can plan pregnancy no earlier than 6-12 months later. This is due to the fact that during this time there is a risk of abnormal development of the fetus under the influence of high levels of vitamin A in the body. The drug contains sugar, which should be taken into account in patients with diabetes. The drug is not recommended to be prescribed together with other multivitamins, since an overdose of the latter in the body is possible. The drug contains wheat flour as an excipient, which should be taken into account by patients with celiac disease. Urine may turn yellow, which is completely harmless and is explained by the presence of riboflavin in the drug.

Interaction with other drugs

Vitamins A and E mutually enhance the effect and are synergists. Vitamin A reduces the anti-inflammatory effect of glucocorticoids. It cannot be used simultaneously with nitrites and cholestyramine, as they interfere with the absorption of retinol. Vitamin A should not be prescribed with retinoids, as their combination is toxic. Vitamin E should not be used together with iron, silver, alkaline agents (sodium bicarbonate, trisamine), or indirect anticoagulants (dicoumarin, neodicoumarin). Vitamin E enhances the effect of steroidal and non-steroidal anti-inflammatory drugs (sodium diclofenac, ibuprofen, prednisolone). Medicines containing iron inhibit the effect of vitamin E. Vitamin C enhances the effect and toxicity of sulfonamides (possibility of crystalluria), penicillin, increases the absorption of iron, the absorption of aluminum (take into account during simultaneous treatment with antacids containing aluminum), reduces the effectiveness of heparin and indirect coagulants. Large doses of the drug reduce the effectiveness of tricyclic antidepressants, neuroleptics - phenothiazine derivatives, tubular reabsorption of amphetamine, and interfere with the excretion of mexiletine by the kidneys. Ascorbic acid can be used only 2 hours after the injection of deferoxamine. Long-term use of large doses of the drug reduces the effectiveness of treatment with disulfiram. Ascorbic acid increases the overall clearance of ethyl alcohol. Ascorbic acid increases the excretion of oxalates in the urine and increases the risk of crystalluria during treatment with salicylates. The absorption of vitamin C is reduced when used simultaneously with oral contraceptives, consumption of fruit or vegetable juices, and alkaline drinking. Folic acid, when used simultaneously with antithrombotic drugs, increases the risk of bleeding, with antihypertensive drugs - leads to increased arterial hypotension, with lipid-lowering drugs - increases the risk of their toxic effects, with antidiabetic drugs - reduces the glucose-lowering effect of the latter, with methyldopa or beta blockers. adrenergic receptors - leads to a significant decrease in blood pressure, with probenecid - reduces the effect of probenecid. Folic acid reduces plasma concentrations of phenytoin; when used with other antiepileptic drugs, a mutual decrease in clinical effectiveness is possible. Vitamin B6 weakens the effect of levodopa, prevents or reduces the toxic effects observed with the use of isoniazid and other anti-tuberculosis drugs. Vitamin B1, influencing polarization processes in the area of ​​neuromuscular synapses, can weaken the curare-like effect of muscle relaxants. Vitamin B2 is incompatible with streptomycin and reduces the effectiveness of antibacterial drugs (oxytetracycline, doxycycline, erythromycin, tetracycline and lincomycin). Tricyclic antidepressants, imipramine and amitriptyline, inhibit the metabolism of riboflavin, especially in cardiac tissue. PAS (para-aminosalicylic acid), cimetidine, calcium supplements, ethyl alcohol reduce the absorption of vitamin B12. Prescribe with caution to patients with angina, unstable angina and acute myocardial infarction, patients receiving nitrates, calcium channel antagonists and beta blockers. Cases of rhabdomyolysis have been reported when nicotinic acid was used with lovastatin.

Contraindications

Hypersensitivity to any components of the drug, nephrolithiasis, severe renal dysfunction, chronic glomerulonephritis, gout, hyperuricemia, erythremia, erythrocytosis, tendency to thrombosis, thrombophlebitis, thromboembolism, thyrotoxicosis, chronic heart failure, history of sarcoidosis, active peptic ulcer of the stomach and duodenum (due to a possible increase in the acidity of gastric juice), severe liver dysfunction, active hepatitis, neoplasms (except for cases accompanied by megaloblastic anemia), arterial hypertension (severe forms), hypervitaminosis A and E, impaired iron and copper metabolism, hypercalcemia, fructose intolerance, glucose-galactose malabsorption syndrome.

Compound

Active ingredients: 1 tablet contains vitamin A (in the form of vitamin A palmitate) - 3300 MO (1.817 mg) or vitamin A (in the form of retinol acetate) - 3300 MO (1.135 mg), vitamin E (in the form of α-tocopherol acetate) - 10 mg, vitamin B1 (in the form of thiamine hydrochloride) - 2 mg, vitamin B2 (riboflavin) - 2 mg, vitamin B6 (pyridoxine hydrochloride) - 3 mg, vitamin B12 (cyanocobalamin) - 2 mcg, vitamin C (ascorbic acid) - 75 mg, nicotinamide - 20 mg, folic acid - 0.07 mg, rutin - 10 mg, calcium D-pantothenate - 3 mg, excipients: wheat flour, starch syrup, talc, light mineral oil, sugar, yellow wax, flavoring "mint aroma"

Overdose

In case of an overdose of the drug, dyspeptic symptoms (nausea, vomiting, diarrhea, epigastric pain), allergic reactions (itching, skin rash), changes in the skin and hair, liver dysfunction, headache, drowsiness, lethargy, facial flushing, irritability. In such cases, the use of the drug should be discontinued. Therapy is symptomatic. With long-term use of vitamin C in large doses, it is possible to inhibit the function of the insular apparatus of the pancreas, change the renal secretion of ascorbic and uric acids during acetylation of urine with the risk of precipitation of oxalate stones.

Side effect

When using the drug in recommended doses, the following adverse reactions are possible. From the immune system: hypersensitivity reactions to the components of the drug, including anaphylactic shock, angioedema, bronchospasm; from the cardiovascular system: arterial hypertension; from the skin and subcutaneous tissues: rash, urticaria, itching, redness; from the gastrointestinal tract: dyspeptic disorders, nausea, vomiting, stomach pain, belching, constipation, diarrhea, increased secretion of gastric juice; from the nervous system: headache, dizziness, increased excitability, drowsiness, sleep disturbance, increased fatigue; from the organs of vision: blurred vision, dry skin/mucous membranes of the eyes; from the metabolic side: hypercalcemia, hypercalciuria, crystalluria, glucosuria; from the blood and lymphatic system: blood coagulation disorders, hemolysis of erythrocytes in patients with glucose-6-phosphate dehydrogenase deficiency; general disorders: hot flashes, which may be accompanied by a feeling of palpitations, irritability, sweating, hyperthermia; others: yellow coloration of urine. During long-term use of high doses, the following adverse reactions may occur. Metabolism: hyperuricemia, impaired glucose tolerance, hyperglycemia, impaired zinc and copper metabolism; from the nervous system: paresthesia, convulsions, anorexia; from the cardiovascular system: arrhythmias, arterial hypotension; from the blood and lymphatic system: erythrocytopenia, neutrophilic leukocytosis; from the gastrointestinal tract: gastrointestinal disorders; from the skin and subcutaneous tissues: hair loss, seborrhea, hyperpigmentation, dryness and cracks on the palms and soles; from the kidneys and urinary tract: impaired renal function, renal failure; from the liver and biliary tract: jaundice, fatty liver; from the musculoskeletal and connective tissue side: myalgia, myopathy; laboratory data: temporary increase in the level of aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase, increase in the level of uric acid in the blood, electrolyte imbalance.

Storage conditions

Store in original packaging at a temperature not exceeding 25 °C. Keep out of the reach of children.

Buy Undevit-KV etc. in containers (bans) No. 50 in pack No. 1 in the pharmacy

Price for Undevit-KV etc. in containers (bans) No. 50 in pack No. 1

Instructions for use for Undevit-KV etc. in containers (bans) No. 50 in pack No. 1

Hexavit for hypovitaminosis

Hexavit is one of the multivitamin products recommended for patients with hypovitaminosis or other negative conditions. It has a low cost, no more than 40 rubles. The main effect on the body is provided due to the content of the following substances:

• ascorbic acid;
• nicotinamide;
• pyridoxine;
• retinol;
• riboflavin;
• thiamine

The product is indicated for use in cases of hypovitaminosis, deterioration of the immune system, decreased vision, and long-term treatment with antibiotics. It supplies the body with the correct ratio of vitamins, so a positive effect occurs.

Apart from an allergic reaction, no other side effects were identified when using the product.

The drug is contraindicated in hypervitaminosis, chronic inflammatory diseases of the gastrointestinal tract (intestinal obstruction, peptic ulcer, irritable bowel syndrome), pregnancy and lactation, minors, intolerance to active and auxiliary components. Most contraindications are associated with limited research of the drug in laboratories and on patients. Sufficient testing has not been carried out.

Contraindications, side effects

Prohibitions on use include conditions associated with acute inflammatory processes in the gastrointestinal tract. Do not take the drug if you have a stomach ulcer or if you are affected by ulcers and erosions of the duodenum. Also, the body will react poorly to treatment for acute enteritis and colitis.

It is forbidden to drink the complex if you have cirrhosis and other severe liver diseases, or liver failure.

Some people experience intolerance to the components included in the composition and experience allergic reactions. This mainly concerns additional substances, but in some cases an allergic reaction to certain vitamins develops.

Pregnant women are not prohibited from taking it, but it is important to strictly monitor the amount of vitamin A entering the body in order to completely prevent an overdose. The same information applies to the period of breastfeeding. It is prohibited to exceed the daily dose; an overdose of individual components may occur.

What is Revit?

Revit is an inexpensive set of vitamins, the price of which does not exceed 70 rubles. The composition includes only retinol, thiamine, riboflavin, ascorbic acid. Due to them, the main effect on the body is ensured. Therefore, the following indications for use are distinguished:

• treatment or prevention of hypovitaminosis, vitamin deficiency;

• pregnancy, lactation;
• severe mental and physical stress with gradual exhaustion of the body;
• condition after an infection.

Side effects are rare. An allergic reaction may develop. The drug is contraindicated in case of individual intolerance. It can be used by pregnant women or children, but with caution. The concentration of the drug can be found out from the attending physician or from the instructions for use.

It is important to consider that ascorbic acid increases the absorption of certain medications. Among them are antibiotics, anticoagulants, and iron. This is important when using combination therapy. Otherwise, there may be a large load on the liver, kidneys, pancreas, and other internal organs. The risk of tissue inflammation increases.

Instructions for use

The product should be taken only during meals, immediately after meals. For adolescents over 14 years of age, adults, the dosage rate is 1 tablet/day. Specific treatment recommendations are given below:

• for severe mental stress - 2 tablets/day;
• when recovering from infections - 2-3 tablets/day;
• for severe vitamin deficiency - 3 tablets/day;
• for the prevention of vitamin deficiency in spring and winter - 1 tablet/day;
• pregnant women from the 2nd trimester, during lactation - 1-2 tablets/day.

Typically the course of therapy is 21-30 days. Repeated courses are allowed, but not earlier than 30-90 days from the end of the first course. It is advisable to take vitamins as prescribed by a doctor; without recommendations, it is permissible to carry out 1 therapeutic course.

In case of overdose, nausea and vomiting and diarrhea most often occur.

In addition to dyspeptic reactions, an overdose can cause pain in the abdomen, in the stomach area, allergies, migraines, lethargy and drowsiness. People with liver disease are at high risk of liver dysfunction. In all cases of overdose, you should immediately stop taking Undevit.

Similarities of drugs

The main similarity among medicines is the presence of vitamin composition. But many therapists or pediatricians also highlight a number of other features that allow the use of drugs as analogues or substitutes:

• low price category, one package of each product does not exceed 100 rubles. by cost;
• the presence of a large number of vitamins that have a beneficial effect on a person’s health in case of hypovitaminosis, recovery from an infectious disease;
• the form of production of all drugs is only in tablets for oral use;
• a small number of side effects and contraindications, which allows almost all patients to use the medicine;
• no effect on concentration, which allows the patient to drive a vehicle during the treatment period;
• It is not recommended to use several types of multivitamin preparations together, otherwise hypervitaminosis will occur, which also negatively affects your well-being.

If the patient decides to buy similar products due to the risk of side effects, you should carefully read the composition. For example, a patient may be intolerant to artificial thiamine. Then the doctor will recommend a product that does not contain it.

Differences between multivitamins

Despite the fact that all these products belong to multivitamin complexes, they have many differences. This should be taken into account when replacing a prescribed drug with an analogue. All data is shown in the table.

Based on the table, you can understand that despite the presence of a large number of vitamins, the products have differences. They should be taken into account when initially prescribing the drug, the presence or absence of combination therapy. If the patient develops a rash, itching, burning, peeling, inflammation of the skin or mucous membrane, the drug is discontinued.

Indications of the product

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The main indication is hypovitaminosis (avitaminosis) in children over 14 years of age and adults. Symptoms of this condition usually appear in late winter and include weakness, lack of energy, brittle nails, hair loss, pale and dry skin. Other possible indications for use:

• metabolic disorders in older people;
• slow fat metabolism, high cholesterol, obesity;
• taking a course of antibiotics, hormonal agents and other medications that negatively affect the immune system;
• past viral, fungal, bacterial infections;
• high loads - physical, intellectual;

• operations, especially those accompanied by difficult rehabilitation;
• in adolescents it is a time of intensive growth.

The drug can be taken even without specific indications during periods when the diet does not include enough vitamins. Among women, the complex is popular for improving the condition of the skin and prolonging its youth by stimulating collagen production. A course of taking Undevit increases immunity, improves liver and heart function, and optimizes overall well-being.

Why is vitamin therapy needed?

All human organs, tissues, and cells require constant delivery of nutrients, minerals and vitamins. Thanks to them, metabolism, protective immune reactions, and tissue regeneration improve. Therefore, the diet of any person should contain a sufficient amount of useful substances that regulate the activity of his body.

If there are not enough vitamins in food, the quality of teeth, hair, nails, skin, and internal organs deteriorates. In this case, doctors advise starting therapy with multivitamin preparations. Not all of them are suitable for every patient.

It is required to first undergo laboratory tests to find out which components are missing.

Using the data obtained, the doctor can accurately understand which drug to prescribe if the patient is diagnosed with hypovitaminosis. For example, during pregnancy you need large doses of folic acid. Additionally, you will need calcium, thiamine, riboflavin and other substances. It is on their basis that a product should be produced to replenish the entire volume of required substances so that the woman and fetus are normal.

It is recommended to look through analogues of drugs, choosing the highest quality ones. If we consider Revit, Hexavit, Undevit, Gendevit, many similarities can be identified. But due to the different composition, different effects on the body occur.