Pharmacodynamics and pharmacokinetics
This enzyme agent can compensate for the insufficiency of the secretory function of the pancreas, as well as the biliary activity of the liver.
The enzymes contained in pancreatin - protease, amylase and lipase - help facilitate the digestion of proteins and carbohydrates, improving the absorption of these components in the small intestine.
It is known that the enzyme hemicellulase improves the breakdown of plant fiber and digestive processes, reducing the formation of gases.
Bovine bile extract is also characterized by a choleretic effect, improved emulsification of fats, normalization of absorption of fats or fat-soluble vitamins , and increased lipase activity.
Indications for use of Festal
The main indications for the use of Festal are insufficiency of the pancreas, accompanied by chronic pancreatitis , as well as biliary insufficiency with impaired digestion of food, flatulence, constipation , and so on in the treatment of:
- diffuse liver diseases, for example, liver cirrhosis , alcoholic and toxic liver damage;
- large losses of bile acids, for example, after cholecystectomy ;
- disruptions in the circulation of bile acids, as a result of biliary dyskinesia, dysbacteriosis and malabsorption;
- deviations in the digestion of food in people with normal gastrointestinal tract function due to changes in nutrition, problems with chewing function, a sedentary lifestyle, and so on;
- violations of the neurohumoral regulation of various processes of bile formation or bile secretion, accompanied by chronic gastrointestinal diseases, for example, chronic forms of gastritis, duodenitis or cholecystitis;
- as well as in preparation for an abdominal ultrasound or x-ray.
What does Festal help with?
The main indications for taking an enzyme preparation is a decrease in the activity of the pancreas and hepatolienal system, which is accompanied by symptoms of dyspepsia, increased gas formation, and impaired digestion of food.
Festal is prescribed for:
- Toxic, medicinal and alcoholic hepatitis, liver cirrhosis.
- Chronic pancreatitis.
- Malabsorption syndrome.
- Dysbacteriosis.
- Gastritis, duodenitis, enteritis, colitis.
- Other pathological conditions of the gastrointestinal tract, accompanied by impaired digestion and absorption of food.
Contraindications for use
Main contraindications to the use of Festal:
- high sensitivity to its components;
- hepatitis;
- acute pancreatitis or exacerbation of its chronic form;
- liver failure , coma or precoma;
- hyperbilirubinemia;
- intestinal obstruction, empyema of the gallbladder, tendency to diarrhea ;
- patient age under 3 years;
- obstructive jaundice and various gallstone diseases.
Nosological classification (ICD-10)
- K29.5 Chronic gastritis, unspecified
- K29.9 Gastroduodenitis, unspecified
- K59.0 Constipation
- K63.8.0* Dysbacteriosis
- K70 Alcoholic liver disease
- K71 Liver toxicity
- K74.6 Other and unspecified cirrhosis of the liver
- K81.1 Chronic cholecystitis
- K82.8.0* Dyskinesia of the gallbladder and biliary tract
- K86.1 Other chronic pancreatitis
- K86.8.0* Hypofunction of the pancreas, exocrine
- K86.9 Disease of the pancreas, unspecified
- K90 Intestinal malabsorption
- K92.9 Disease of the digestive system, unspecified
- K94* Diagnosis of gastrointestinal diseases
- R14 Flatulence and related conditions
- Z72.4 Inappropriate diet and unhealthy eating habits
- Z98.8 Other specified postsurgical conditions
Festal during pregnancy
It should be noted that Festal is prescribed with extreme caution pregnancy As a rule, you should check with your doctor to find out whether pregnant women can take this or other medications. According to the instructions, the use of this drug during breastfeeding and pregnancy is allowed if the benefit for treating a woman significantly outweighs the risk of developing undesirable effects for the baby.
Instructions for use of Festal (Method and dosage)
This medicine is intended to be taken orally as a whole, together with or immediately after eating, with water.
The average daily dosage is 1-2 tablets for 3 times a day. Increasing the dose is possible only as prescribed by a doctor. Before an x-ray or ultrasound, the drug is taken 2-3 days before the examination, 2 pieces 2-3 times a day.
At the same time, the instructions for using Festal for children indicate that when prescribing the drug to a small patient, the dose is determined by the attending physician.
The duration of therapy depends on the complexity of the disorder and can range from several days to years.
Special instructions for the use of the drug Festal
the drug contains glucose and sucrose, which should be taken into account in patients with diabetes. During the recovery period or when expanding the diet, the drug can be taken only as prescribed by a doctor. Use during pregnancy and lactation. The use of the drug during pregnancy and lactation is possible if, in the opinion of the doctor, the expected positive effect for the mother exceeds the potential risk for the fetus/child. Children . The drug is intended for use in adults. The ability to influence the reaction rate when driving a vehicle or operating other mechanisms. Does not affect.
How to give Festal to children?
Children often have various problems in the gastrointestinal tract and therefore they may be prescribed enzyme preparations.
Festal often helps eliminate bloating, pain and discomfort in the abdomen, and problems with bowel movements. This drug can be used for children only from 3 years of age. In this case, the dosage for children is determined by the attending physician.
The medicine should be given immediately with food or a short time after. If the tablets are difficult for a child to swallow, they can be pre-dissolved in liquid.
Interaction
The combination of the drug with sulfonamides, antibiotics and iron supplements can have different effects on their absorption.
Antacids containing magnesium hydroxide or calcium carbonate can reduce the effectiveness of Festal.
Simultaneous use with Cimetidine may enhance its effect.
Compound
Dragee | 1 dragee |
core | |
active substances: | |
pancreatin | 192 mg |
(equivalent to amylase - 4500 FIP units; lipase - 6000 FIP units; protease - 300 FIP units) | |
hemicellulase | 50 mg |
bile components | 25 mg |
excipients: sodium chloride | |
shell: cellacephate (cellulose acetate phthalate); ethyl vanillin; Castor oil; sucrose; methyl parahydroxybenzoate (methylparaben); propyl parahydroxybenzoate (propylparaben); gelatin; liquid dextrose (liquid glucose); talc; calcium carbonate; acacia gum; glycerol (glycerol); macrogol (polyethylene glycol 6000); titanium dioxide |
Festal's analogs
Level 4 ATC code matches:
Digestin
Creon
Pancitrate
Mezim
Pankreoflat
Pancreazim
Enterosan
Panzinorm Forte
Panzinorm
Micrasim
Enzistal P
Pancreatin
Penzital
Pangrol
Hermital
Abomin
The main analogues of Festal: Digestal, Pancreatin, Creon, Mezim Forte and Pangrol.
Festal or Creon - which is better?
Before you think about which of these drugs to take, you need to find out what Festal helps with, what it is needed for, and what disorders does Creon ? To do this, you need to compare the symptoms of the disease and the indications for which these drugs are prescribed. Of course, for this it is better to consult a doctor.
As for the effectiveness of these two drugs, according to experts, Creon is higher, and it has more advantages. Creon is offered in a more convenient form of release - capsules, and has an improved principle of action - granules dissolve well in the small intestine.
In addition, Creon has more indications for use and fewer contraindications. This remedy can also be taken by children from 1 year of age.
Reviews about Festal
As numerous reviews of Festal show, it is extremely popular among patients of various groups. According to many patients, this is an excellent, highly effective remedy that helps improve digestion and eliminate many unwanted symptoms. There are also many people who have to take Festal N for many years, for example, with constant functional deficiency in the digestive system. Due to the natural origin and high degree of purification of this drug, it is often used as a substitute for its own enzymes.
In addition, there are many messages on the Internet from users who take such drugs for any digestive disorder. At the same time, they are trying to choose the best medicine for themselves and are interested in the forums about Festal tablets, why they help, how to take them before or after meals, and so on.
It is possible that some people are using this remedy for other purposes, since they do not know exactly what it helps with. It should be noted that they will not immediately feel the development of undesirable effects if used incorrectly, but over time this will certainly appear. If a person regularly has digestive problems, then you need to contact a gastroenterologist, who will conduct a full examination and write a prescription in Latin prescribing the necessary treatment.
Festal price, where to buy
The price of Festal in Moscow is 120-590 rubles.
In Ukraine, the medicine can be bought in Kyiv, as well as in cities such as Kharkov, Dnepropetrovsk, etc., the cost of the drug varies between 53-75 UAH.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Festal - tablets 40 pcs., three-component enzyme agentAventis Pharma/Sanofi India
RUB 206.order - Festal other intestinal digestions. 10 pcs. Sanofi India Limited
92 rub. order
- Festal - tablets 100 pcs., three-component enzyme agentAventis Pharma/Sanofi India
RUR 733 order
- Festal - tablets 20 pcs., three-component enzyme agentAventis Pharma/Sanofi India
RUB 154 order
Pharmacy Dialogue
- Festal three-component enzyme tablet No. 100Aventis Pharma
RUR 776 order
- Festal three-component enzyme tablet No. 20Sanofi Aventis
RUB 151 order
- Festal three-component enzyme tablet No. 100Sanofi Aventis
RUR 733 order
- Festal three-component enzyme dragee No. 40Sanofi Aventis
RUB 269 order
- Festal three-component enzyme tablet No. 10Sanofi Aventis
87 RUR order
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Pharmacy24
- Festal Neo 10000 N20 tablets LLC "Pharmex Group", m. Boryspil, Ukraine
60 UAH. order
PaniPharmacy
- Festal neo tablets Festal Neo 10000 tablets. No. 20 Ukraine, Pharmex Group LLC
69 UAH order
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Manufacturer
Sanofi India Limited, India
Legal entity in whose name the registration certificate is issued: Sanofi India Limited, India.
Release quality control:
1. Sanofi India Limited, India.
2. JSC "BIOKOM", Russia. 355016, Stavropol, Chapaevsky proezd, 54.
Tel., 36-53-54; Fax.
Consumer complaints should be sent to the address in Russia: 125009, Moscow, st. Tverskaya, 22.
Tel.; Fax.
If the drug is packaged at ZAO BIOCOM, consumer complaints should be sent to the address of ZAO BIOCOM.