Buy Nootropil solution for internal use 20% 125ml No. 1 in pharmacies

Compound

Piracetam is the active ingredient of the drug.
The tablets contain 800 or 1200 mg of this substance. Additional elements: macrogol 6000, silicon dioxide, croscarmellose sodium, magnesium stearate.

Capsules of 400 mg of active ingredient. Additional substances: macrogol 6000, silicon dioxide, lactose monohydrate, magnesium stearate.

The oral solution contains 200 or 330 mg of active substance per 1 ml. Additional elements of the composition are: sodium saccharinate, pure water, glycerol , sodium acetate, acetic acid, methyl parahydroxybenzoate, flavorings, propyl parahydroxybenzoate.

Nootropil solution IV and IM contains 200 mg of active substance per 1 ml. Auxiliary elements are: sodium acetate trihydrate, water for injection, glacial acetic acid.

Pharmacodynamics and pharmacokinetics

The active ingredient is piracetam. The use of the drug Nootropil enhances the utilization of glucose, enhances the synthesis of phospholipids and RNA, increases the level of ATP in brain tissue, and stimulates glycolytic reactions . The drug has a positive effect on metabolic processes in brain tissue, facilitates the learning process, improves integrative work and brain activity, and improves memory . Nootropil is able to suppress the aggregation of activated platelets, does not have a vasodilatory effect, but at the same time has a positive effect on microcirculation and the speed of propagation of the excitation wave in brain tissue. In case of brain damage due to intoxication, hypoxia, or electric shock, the drug has a pronounced protective effect, reducing the severity of vestibular nystagmus, reduces delta activity and enhances alpha and beta activity on the electroencephalogram . The medication improves cerebral blood flow, increases mental performance, improves conductivity between synapses in neocortical structures, and has a positive effect on interhemispheric connections. The therapeutic effect of treatment develops gradually. The drug does not have psychostimulating and sedative effects.

The drug is quickly absorbed, is not metabolized, and does not bind to blood proteins. It is excreted unchanged by the kidneys.

Nootropil 800 mg No. 30 tablet p.o.

INSTRUCTIONS FOR MEDICAL USE OF THE MEDICINE NOOTROPIL® TRADE NAME NOOTROPIL® INTERNATIONAL NON-PROPENTED NAME PIracetam DOSAGE FORM FILM-COATED TABLETS, 800 MG COMPOSITION ONE TABLE ITK CONTAINS THE ACTIVE SUBSTANCE – PIRACETAM 800 MG, AUXILIARY SUBSTANCES: SILICON DIOXIDE COLLOIDAL ANHYDROUS, MAGNESIUM STEARATE, POLYETHYLENE GLYCOL 6000, CROSCARMELLOSE SODIUM, COVER COMPOSITION: OPADRAY Y-1-7000 (HYDROXYPROPYL METHYL CELLULOSE, TITANIUM DIOXIDE (E171), POLYETHYLENE GLYCOL 400), OPADRAY OY-S-29019 (HYDROXYPROPYL METHYL CELLULOSE, POLYETHYLENE GLYCOL 6000). DESCRIPTION FILM-COATED TABLETS, WHITE, LONG, WITH SCORES ON BOTH SIDES AND ENGRAVED N ON BOTH SIDES OF SCORES ON ONE SIDE. PHARMACOTHERAPEUTIC GROUP OTHER PSYCHOSTIMULANTS AND NOOTROPIC DRUGS ATC CODE N06BX03 PHARMACOLOGICAL PROPERTIES PHARMACOKINETICS AFTER ORAL USE PIRACETAM IS QUICKLY AND ALMOST COMPLETELY ABSORBED, PEAK CONCENTRATION I AM REACHED 1 HOUR AFTER USE. BIOAVAILABILITY OF THE DRUG IS APPROXIMATELY 100%. AFTER TAKING A SINGLE DOSE OF 2 G, THE MAXIMUM CONCENTRATION IS 40-60 mcg/ml, WHICH IS REACHED IN THE BLOOD AFTER 30 MINUTES. THE APPEARING VOLUME OF DISTRIBUTION OF PIRACETAM IS ABOUT 0.6 L/KG. THE HALF-LIFE OF THE DRUG FROM BLOOD PLASMA IS 4-5 HOURS AND 8.5 HOURS FROM CORESPINAL FLUID, WHICH IS ELONGED IN RENAL FAILURE. THE PHARMACOKINETICS OF PIracetam DOES NOT CHANGE IN PATIENTS WITH LIVER FAILURE. PENETRATES THE BLOOD-BRAIN AND PLACENTAL BARRIER AND MEMBRANES USED IN HEMODIALYSIS. PIRACETAM SELECTIVELY ACCUMULATES IN THE TISSUE OF THE CEREBRAL CORTEX, MAINLY IN THE FRONTAL, PARIETAL AND OCCIPITAL LOBE, IN THE CEREBELLUM AND BASAL GANGLIA. DOES NOT BIND TO BLOOD PLASMA PROTEINS, IS NOT METABOLIZED IN THE BODY AND IS EXCRETED BY THE KIDNEYS IN AN UNCHANGED FORM. 80-100% OF PIRACETAM IS EXCRETED BY THE KIDNEYS IN AN UNMODIFIED FORM BY RENAL FILTRATION. PHARMACODYNAMICS THE ACTIVE COMPONENT OF NOOTROPIL® IS PIRACETAM, A CYCLIC DERIVATIVE OF GAMMA-AMINO-BUTYRY ACID (GABA). NOOTROPIL IS A NOOTROPIL DRUG THAT DIRECTLY AFFECTS THE BRAIN, IMPROVING COGNITIVE (COGNITIVE) PROCESSES SUCH AS LEARNING ABILITY, MEMORY, ATTENTION, AND ALSO MENTAL PERFORMANCE. NOOTROPIL® INFLUENCES THE CENTRAL NERVOUS SYSTEM IN VARIOUS WAYS: BY CHANGING THE RATE OF EXCITATION IN THE BRAIN, IMPROVING METABOLIC PROCESSES IN NERVE CELLS, IMPROVING MICROCIRCULATION, IMPACTS INFLUENCES THE RHEOLOGICAL PROPERTIES OF BLOOD AND DOES NOT CAUSE A VASUDOLATORAL EFFECT. IMPROVES SYNAPTIC CONDUCTION IN NEOCORTICAL STRUCTURES, INCREASES MENTAL PERFORMANCE, IMPROVES CEREBRAL BLOOD FLOW. NOOTROPIL INHIBITS PLATELET AGGREGATION AND RESTORES THE ELASTICITY OF THE erythrocyte membrane, and reduces the adhesion of erythrocytes. WHEN TAKEN AT A DOSE OF 9.6 G, THERE IS A 30% - 40% DECREASE IN FIBRINOGEN AND VILLIBRAND FACTORS AND AN ELONGATION IN BLEEDING TIME. NOOTROPIL HAS A PROTECTIVE AND RESTORATIVE EFFECT WHEN BRAIN FUNCTION IS DISRUPTED DUE TO HYPOXIA AND INTOXICATION. NOOTROPIL REDUCES THE SEVERITY AND DURATION OF VESTIBULAR NYSTAGM. INDICATIONS FOR USE - PSYCHOORGANIC DISORDERS, IN PARTICULAR IN ELDERLY PATIENTS, MANIFESTED BY REDUCED MEMORY, Dizziness, REDUCED CONCENTRATION OF ATTENTION AND REDUCED GENERAL ACTIVITY, MOOD CHANGES, BEHAVIORAL DISORDERS, GAIT DISORDERS AND IN PATIENTS WITH ALZHEIMER'S DISEASE AND SENILIA DEMENTIA OF ALZHEIMER'S TYPE - Dizziness AND ASSOCIATED EQUILIBILITY DISORDERS, EXCEPT FOR DIZZINESS OF VASCULAR AND MENTAL ORIGIN - CORTICAL MYOCLONIUS AS A MONO- OR COMPLEX THERAPY - SICKLE CELL ANEMIA AS A COMPLEX THERAPY - TREATMENT D ISLEXIA IN CHILDREN (IN COMPLEX WITH OTHER METHODS). METHOD OF APPLICATION AND DOSES NOOTROPIL® IS TAKEN ORALLY DURING MEALS OR ON AN EAST SCHATCH WITH LIQUIDS. ATTENTION! TAKE THE LAST SINGLE DOSE NO LATER THAN 5:00 PM TO PREVENT SLEEP DISTURBANCE. THE DAILY DOSE IS RECOMMENDED TO BE TAKEN IN 2-4 SIZES. SYMPTOMATIC TREATMENT OF PSYCHOORGANIC SYNDROME: 4.8 G/DAY DURING THE FIRST WEEK AND THEN GO TO A MAINTENANCE DOSE OF 1.2-2.4 G/DAY TREATMENT OF VERTIGO AND ASSOCIATED EQUILIBRIUM: 2.4 — 4.8 G/ DAILY TREATMENT OF CORTICAL MYOCLONIUS: START WITH A DOSE OF 7.2 G/DAY, EVERY 3-4 DAYS THE DOSE IS INCREASED BY 4.8 G/DAY UNTIL A MAXIMUM DOSE OF 24 G/DAY IS REACHED. TREATMENT CONTINUES DURING THE WHOLE PERIOD OF THE DISEASE. EVERY 6 MONTHS AN ATTEMPT SHOULD BE MADE TO REDUCE THE DOSE OR WITHDRAWAL THE DRUG BY GRADUALLY REDUCING THE DOSE BY 1.2 G/DAY EVERY 2 DAYS. IF THERE IS NO EFFECT OR AN INsignificant THERAPEUTIC EFFECT, THE TREATMENT IS DISCONTINUED. TREATMENT OF SICKLE CELL ANEMIA: THE DAILY PREVENTIVE DOSE IS 160 MG/KG OF BODY WEIGHT, DIVIDED INTO 4 EQUAL DOSES. A DOSE LESS THAN 160 MG/KG OR IRREGULAR TAKING OF THE DRUG MAY CAUSE AN EXacERBATION OF THE DISEASE. TREATMENT OF DYSLEXIA IN CHILDREN (IN COLLECTION WITH OTHER TREATMENT METHODS): RECOMMENDED DAILY DOSE FOR CHILDREN FROM 8 YEARS OLD AND ADOLESCENTS – 3.2 G, DIVIDED INTO 2 ADMISSIONS. SINCE NOOTROPIL® IS EXCLUDED FROM THE BODY BY THE KIDNEYS, WHEN PRESCRIBING THE DRUG TO PATIENTS WITH RENAL FAILURE AND ELDERLY PATIENTS, THE DOSE SHOULD BE ADJUSTED DEPENDING ON THE VALUATION OF CREATININE CLEARANCE (CR). BC FOR MEN CAN BE CALCULATED BASED ON SERUM CREATININE CONCENTRATION USING THE FOLLOWING FORMULA: [140 – AGE (YEARS)] ´ BODY WEIGHT (KG) BC (ML/MIN) = ————————————— ————- 72 X CVS (MG/DL) CV FOR WOMEN CAN BE CALCULATED BY MULTIPLYING THE OBTAINED VALUE BY A COEFFICIENT OF 0.85. NO DOSE CORRECTION IS REQUIRED FOR PATIENTS WITH LIVER FUNCTION IMPAIRMENTS. FOR PATIENTS WITH IMPAIRED RENAL AND LIVER FUNCTIONS, DOSING IS CARRIED OUT ACCORDING TO THE TABLE BELOW. RENAL FAILURE KK (ML/MIN) DOSING REGIMEN NORMAL > 80 USUAL DOSE LIGHT 50-79 2/3 USUAL DOSE IN 2-3 DEPARTMENTS MEDIUM 30-49 1/3 USUAL DOSE IN 2 DETAILS SEVERE <30 1/6 USUAL DOSE ONE MULTIPLE TERMINAL STAGE < 20 CONTRAINDICATED SIDE EFFECTS - HYPERKINESIA, NERVOUSITY, Drowsiness, DEPRESSION, ASTHENIA, - Dizziness, HEADACHES - ATAXIA, IMPAIRED EQUILIBRIUM, ACHIEVEMENT OF EPILEPSY, ANXIETY, HALLUCINATIONS - DER MATITIS, ITCHING, SKIN RASHE, SWELLING - NAUSEA, VOMITING, DIARRHEA, ABDOMINAL PAIN. CONTRAINDICATIONS - INCREASED SENSITIVITY TO PIRACETAM OR PYRROLIDONE DERIVATIVES, AS WELL AS OTHER COMPONENTS OF THE DRUG - PSYCHOMOTOR EXCITATION AT THE TIME OF PRESCRIPTION OF THE DRUG - HUNTINGTON'S CHOREA - ACUTE CEREBRAL CIRCULATION (HEMORRHA) GYCAL STROKE) - TERMINAL STAGE RENAL FAILURE (CC < 15 ML/MIN) - CHILDHOOD UP TO 6 YEARS - PREGNANCY AND LACTATION WITH CAUTION: - IMPAIRED HEMOSTASIS - EXTENSIVE SURGICAL INTERVENTIONS - SEVERE BLEEDING Drug interactions Nootropil increases the effectiveness of thyroid hormones and antipsychotic drugs (neuroleptics). When administered simultaneously with antipsychotics, nootropil reduces the risk of extrapyramidal disorders. When used simultaneously with drugs that stimulate the central nervous system, their effect on the central nervous system may be enhanced. There was no interaction with clonazepam, phenytoin, phenobarbital, or sodium valproate. Nootropil in high doses (9.6 g/day) increases the effectiveness of indirect anticoagulants in patients with venous thrombosis (a more pronounced decrease in platelet aggregation, fibrinogen levels, von Willebrand factors, blood and plasma viscosity was observed compared with the use of indirect anticoagulants only). The possibility of changing the pharmacodynamics of nootropil under the influence of other drugs is low, because 90% of the drug is excreted unchanged in the urine. Nootropil does not inhibit cytochrome P450 isoenzymes. Metabolic interaction with other drugs is unlikely. When taking nootropil at a dose of 20 mg/day, Cmax in the blood plasma and the nature of the pharmacokinetic curve of antiepileptic drugs (carbamazepine, phenytoin, phenobarbital, valproate) in patients with epilepsy receiving constant doses of these drugs do not change. When piracetam 1.6 g was taken together with alcohol, the serum concentrations of piracetam and ethanol did not change. Special instructions When treating cortical myoclonus, abrupt interruption of treatment should be avoided, as this may cause resumption of attacks. When treating sickle cell anemia, a dose of less than 160 mg/kg or irregular use of the drug may cause an exacerbation of the disease. When treating patients on a hyposodium diet, it is recommended to take into account that piracetam tablets at a dose of 24 g contain 46 mg of sodium. Penetrates through the filter membranes of hemodialysis machines. Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms Taking into account possible side effects, care should be taken when driving a car and working with mechanisms. Overdose Symptoms: dyspeptic symptoms such as bloody diarrhea and abdominal pain. Treatment: immediately after taking the drug orally, you can rinse the stomach or induce artificial vomiting. Symptomatic therapy is recommended, which may include hemodialysis. There is no specific antidote. The effectiveness of hemodialysis for piracetam is 50-60%. Release form and packaging: 15 tablets in PVC/aluminum foil strip packaging. 2 contour packages together with instructions for medical use in the state and Russian languages ​​are placed in a cardboard box. Storage conditions: In a dry place at a temperature not exceeding +25°C. Keep out of the reach of children! Shelf life 4 years Do not use after the expiration date indicated on the package! Conditions for dispensing from pharmacies By prescription Manufacturer: USB Pharma S.A. Cheman du Foret B-1420 Brain-l'Alley, Belgium Address of the organization that accepts claims from consumers regarding the quality of products (products) in the Republic of Kazakhstan Representative office in the Republic of Kazakhstan, 050000, Almaty, st. Tolebi 69, office 21 tel.: +, fax

Indications for use of Nootropil

Instructions for use of the drug Nootropil recommend prescribing the drug in neurology, narcology and psychiatry.

In neurological practice, the medication is used for pathology of the nervous system, accompanied by disturbances in the emotional-volitional sphere (for example, Alzheimer's disease) and a decrease in intellectual and mental functions. The drug is prescribed after intoxication and traumatic brain damage, for chronic cerebrovascular insufficiency (headaches, severe dizziness, speech disorders, attention, memory), for vascular pathology of brain tissue, for comatose and subcomatose states, during the period of convalescence in order to increase mental and motor activity, with residual effects of cerebral circulatory disorders according to the ischemic variant.

Indications for the use of Nootropil in psychiatry: flaccid apathetic defective conditions (such as psychoorganic syndrome, schizophrenia), asthenodepressive syndrome (with a predominance of ideator inhibition, with senesto-hypochondriacal disorders, asthenic pathology, with adynamia), nephrotic syndrome . Piracetam is prescribed in the complex treatment of depressive conditions that are resistant to the effects of antidepressants, in the treatment of mental pathology that occurs on “organically defective soil.” The drug is recommended for use in cases of intolerance to neuroleptics and antipsychotic medications in order to eliminate mental, neurological and somatovegetative complications. The drug is prescribed for the cortical form of myoclonus.

Nootropil in drug treatment practice is used to relieve alcohol withdrawal syndrome , in acute poisoning with phenamine , barbiturates , morphine, ethanol, in morphine withdrawal syndrome, chronic alcoholism (in combination with intellectual and mnestic disorders, asthenia, persistent mental pathology). The drug can be used as part of combination therapy in the treatment of sickle cell anemia .

In order to eliminate the consequences of perinatal damage to brain structures, to improve the learning process, in case of cerebral palsy , mental retardation, Nootropil can be used in pediatrics.

Indications for use

The drug is used to treat psychiatric, neurological, and drug-related diseases. It is prescribed in the presence of such pathologies and disorders:

• Alzheimer's disease;
• deterioration of memory and other intellectual functions;
• intoxication;
• various brain injuries;
• headaches;
• dizziness;
• speech problems;
• comatose states;
• pathology of cerebral vessels;
• period of convalescence;
• defective conditions, including schizophrenia;
• nephrotic syndrome;
• lethargy;
• hypochondria;
• depressive states;
• withdrawal syndrome due to alcoholism;
• acute poisoning with certain drugs (including when using barbiturates, morphine);
• sickle cell anemia (as an additional therapy);
• perinatal brain damage (including mental retardation in children, cerebral palsy).

Nootropil is often used in cases of intolerance to antipsychotic drugs. It is used to overcome side effects associated with somatovegetative and neurological complications.

Contraindications

The medication is not used for hemorrhagic stroke , with severe pathology of the renal system, or with intolerance to the main substance piracetam. During pregnancy, severe bleeding , after extensive surgical interventions, with pathology of hemostasis and during breastfeeding, Nootropil is prescribed with caution, assessing the possible risks.

Side effects

There are the following side effects during treatment: vomiting, nausea, disturbances in concentration, imbalance, motor disinhibition, mental agitation, gastralgia , sleep disturbances, anxiety, appetite disturbances, stool disturbances, increased sexual activity, convulsive syndrome , extrapyramidal disorders, headache, dizziness, tremors of extremities. When angina is diagnosed, the course of the disease worsens. Most often, side effects are recorded when the recommended dose of 5 g per day is exceeded.

Contraindications and side effects

The product has few contraindications. Taking Nootropil is completely excluded only in the presence of hemorrhagic stroke and severe kidney pathologies or acute failure. Another indicator of absolute contraindications is individual intolerance to piracetam or other substances included in the tablets, capsules or solution.

Pregnant and lactating women (at any stage) should use Nootropil with caution. Also, careful use is carried out in the presence of chronic diseases, acute conditions that disrupt homeostasis.

In some cases (especially often when the daily norm exceeds 5 g), taking Nootropil gives a number of side effects:

• nausea;
• vomit;
• deterioration in concentration;
• mood swings;
• retardation of movements;
• mental overexcitation;
• sleep problems;
• high level of anxiety;
• appetite disorders;
• gastralgia;
• increased sexual desire;
• headaches;
• tremor;
• dizziness.

Attention!

Taking the medicine may make your angina worse. Patients suffering from this disease should take the drug only under the supervision of a doctor and in accordance with the dosage.

Instructions for use of Nootropil (Method and dosage)

The drug is prescribed intravenously, intramuscularly and orally.

Instructions for the solution

The initial dosage of the drug for parenteral intravenous administration is 10 g. In severe pathology, the medication is administered intravenously by drip up to 12 g per day, the duration of the infusion is 20-30 minutes. Once the therapeutic effect is achieved, the amount of the drug is reduced with a gradual transition to oral administration.

Nootropil tablets, instructions for use

The drug is taken twice a day, the daily dosage is 30-160 mg per 1 kg. It is possible to increase the frequency of administration to 3-4 times a day if necessary. The course of treatment under this regimen is up to 2-6 months.

When treating memory disorders and cognitive disorders, the medication is prescribed orally at the initial stages of therapy, 1600 mg three times a day, then the amount of the drug is reduced to 800 mg.

Treatment of cerebrovascular diseases in the acute stage should begin as soon as possible with a dose of 12 g per day for two weeks, then switch to a dosage of 6 g per day.

Therapy for cortical myoclonus begins with 7.2 g per day with a gradual increase in the amount of active substance by 4.8 g per day every 3-4 days. The maximum dose is 24 grams in 24 hours.

The daily dosage for sickle cell anemia is 160 mg per 1 kg (4 doses). During a crisis period, the dose is increased to 300 mg per 1 kg.

In case of renal dysfunction, the drug is used with caution. The dose is prescribed by the doctor.

How to take a drug to improve memory?

You need to take the medicine 2 times a day. The following dosage is recommended to improve memory - 8 ml of a 20% solution for oral administration.

Instructions for use "Nootropil"

The drug is used intravenously (dropper), intramuscularly (injection) and orally. Instructions for using the solution:

1. Intravenous injection in the amount of 10 g per day.
2. Severe pathology - increase the dosage to 12 g;
3. The duration of the droppers is no more than 30 minutes.
4. After achieving a stable result, they switch to taking Nootropil tablets or other medications.

Instructions for use of tablets depend on the type of disease and patient’s condition:

1. As a general rule, tablets are taken 2 times a day, calculating the dosage in an amount of 30 to 160 g per 1 kg of body weight.
2. Memory and attention disorders - 3 times a day, single dose of 1600 mg, then the dosage is reduced by 2 times.
3. Cerebrovascular pathologies in the acute stage - initial dosage 12 g per day, after 14 days - 6 g.
4. Cortical myoclonus - daily dose is 7.2 g, then daily it is increased by 4.8 g, if necessary, reaching a maximum of 24 g.
5. Sickle cell anemia - the dosage is calculated based on the ratio of 160 mg per 1 kg of body weight, taken 4 times a day. The maximum amount is 300 mg per 1 kg of weight.

Attention!

In case of overdose, seek emergency help. The patient is given gastric lavage, vomiting is induced, and hemodialysis is performed if necessary.

special instructions

Treatment with Nootropil requires regular monitoring of the functioning of the renal and hepatic systems, the state of peripheral blood , the level of creatinine and residual nitrogen. Drug therapy can be combined with psychoactive drugs and medications for the treatment of cardiovascular diseases. Treatment of acute lesions of tissues and structures of the brain is recommended to be carried out in combination with methods of restorative medicine and detoxification therapy . For psychiatric diseases, psychoactive drugs are simultaneously prescribed. Abrupt discontinuation of the medication is unacceptable, especially when treating patients suffering from cortical myoclonus ( due to the high risk of recurrence of seizures and seizures). If side effects such as insomnia or excessive drowsiness develop, it is recommended to stop taking the medication in the evening. During hemodialysis, Nootropil penetrates through special filter membranes in the device. Piracetam affects the ability to drive a vehicle.

The drug is not described in Wikipedia.

Buy Nootropil solution for internal use 20% 125ml No. 1 in pharmacies

Nootropil Buy Nootropil in pharmacies Nootropil in the drug directory DOSAGE FORMS solution for internal use 20% oral solution 200 mg/ml

MANUFACTURERS NextPharma S.a.S (France) USB S.A. Pharma Sector (Belgium)

GROUP Nootropic drugs

COMPOSITION Active substance - piracetam.

INTERNATIONAL NON-PROPENTED NAME Piracetam

SYNONYMS Lucetam, Memotropil, Nootobril, Noocetam, Piratropil, Piracetam, Piracetam MS, Piracetam Obolenskoe, Piracetam-Akos, Piracetam-Vial, Piracetam-Ratiopharm, Piracetam-Richter, Piracetam-Rusfar, Piracetam-Ferein, Piracetam-E scom, Cerebril, Escotropil

PHARMACOLOGICAL ACTION Pharmacological action is nootropic. Activates associative processes of the brain, improves memory, mood and mentality in healthy and sick people. Increases integrative brain activity and intellectual activity, stimulates learning processes, restores and stabilizes impaired brain functions. Increases the resistance of brain tissue to hypoxia and toxic influences, enhances the synthesis of nuclear RNA in the brain. Improves microcirculation (without vasodilation), blocks platelet aggregation, optimizes the conformational properties of the erythrocyte membrane and the ability of erythrocytes to pass through microvessels. In patients with dementia due to repeated cerebrovascular accidents, it improves the local uptake of oxygen and glucose by brain tissue, and in patients with functional disorders of the central nervous system, it increases the level of wakefulness. Due to its antihypoxic effect, it is effective in complex therapy of myocardial infarction. Reduces the severity of vestibular nystagmus. It is quickly and almost completely absorbed when taken orally. Bioavailability is 100%. Does not bind to plasma proteins. The maximum concentration in the liquor is created after 2-8 hours. Penetrates all organs and tissues, passes the placental barrier. Selectively accumulates in the cerebral cortex, mainly in the frontal, parietal and occipital lobes, cerebellum and basal ganglia. Practically not metabolized. The plasma half-life is 4-5 hours; cerebrospinal fluid - 6-8 hours. Excreted by the kidneys. In patients with renal failure, the half-life is prolonged.

INDICATIONS FOR USE Psychoorganic disorders of vascular, traumatic and toxic origin (comata, acute phase of traumatic brain injury, etc.), psychoorganic syndromes with a predominance of asthenia, decreased attention and thinking abilities (cerebral atherosclerosis, intoxication, alcoholism, etc.), alcohol withdrawal and relief of alcoholic delirium, acute poisoning with morphine and barbiturates, psychosis and asthenodepressive states (complex therapy), flaccid apathetic defective states in schizophrenia, depressive states resistant to antidepressants; in gerontology: memory impairment, dizziness, changes in personality traits, Alzheimer's disease, atherosclerotic discirculatory encephalopathy, post-stroke mental and physical defects; in pediatrics - prevention and treatment of newborn asphyxia, birth trauma and its consequences, the period of convalescence after meningitis, encephalitis, traumatic brain injury, mental retardation, learning difficulties, memory disorders and intellectual disability; correction of side effects and complications of therapy with psychotropic drugs (asthenia, adynamia, neuroleptic crises with hyperkinesis), cortical myoclonus, sickle cell anemia (complex therapy), viral neuroinfections (to reduce the phenomena of hypoxia and cerebral ischemia).

CONTRAINDICATIONS Hypersensitivity, including to pyrrolidone derivatives; hemorrhagic stroke, severe renal dysfunction, pregnancy, breastfeeding, infancy up to 1 year.

SIDE EFFECTS: Dizziness, tremor, nervousness, agitation, incl. sexual, irritability, anxiety, sleep disturbance, weakness, drowsiness, nausea, vomiting, diarrhea, abdominal pain, increased frequency of attacks of coronary insufficiency.

INTERACTION Increases the effectiveness of antidepressants. In old and senile age, it enhances the effect of antianginal drugs and reduces the need for nitroglycerin.

OVERDOSE Symptoms: more pronounced symptoms of side effects. Treatment: symptomatic.

SPECIAL INSTRUCTIONS Caution is required when prescribing to patients with impaired hemostasis, during major surgical operations or patients with symptoms of severe bleeding. When treating patients with cortical myoclonus, abrupt cessation of treatment should be avoided. Exacerbation of coronary insufficiency occurs in elderly patients; in these cases, it is necessary to reduce the dose or discontinue therapy. If sleep disturbances occur, it is recommended to cancel the evening dose and increase the daytime dose. Use with caution while working for vehicle drivers and people whose profession involves increased concentration. Penetrates through the filter membranes of hemodialysis machines.

STORAGE CONDITIONS Store at room temperature, in a dry place.

Analogues of Nootropil

Level 4 ATX code matches:
Bravinton

Acefen

Carnicetine

Pyracesin

Nooclerin

Semax

Piracetam

Olatropil

Fezam

Vinpocetine

Cerebrocurin

Cavinton Forte

Calcium hopantenate

Glutamic acid

Cephabol

Olanzapine

Cerebrolysate

Pramistar

Sidnocarb

Vinpotropil

Analogues are the following drugs: Biotropil , Lucetam , Piracetam .

The price of Nootropil analogues is lower and higher. For example, Piracetam costs less.

Which is better: Nootropil or Piracetam?

The medicines are generics, that is, they contain one active substance, piracetam, and have a similar effect on the body. The drug Piracetam is domestically produced and therefore costs less, however, it is also considered less purified.

Reviews about Nootropil

According to reviews of Nootropil on the forums, memory pills are very useful. They improve brain activity, help memorize large amounts of information, add energy and invigorate.

The drug also helps for its intended purpose, but does not act immediately. Based on reviews for children who used this medication, Nootropil is also useful for delayed speech development in a child.

The disadvantages include a bitter taste, individual intolerance to the drug, as well as side effects, for example, headaches.

Nootropil price, where to buy

The price of Nootropil tablets is 275 rubles for 30 pieces of 800 mg each. You can buy Nootropil in the same release form in Ukraine for 80-100 hryvnia.

The price of Nootropil 20% solution ampoules of 5 ml is 315 rubles for 12 pieces. In Ukraine - 170 hryvnia.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

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