Pharmacological properties of the drug Solcoderm
Combined preparation for external use. After application to the affected area, it penetrates into the treated tissue and after 1–2 minutes causes a change in its color, which reflects the intravital fixation of the tissues of the treated area. Subsequently, the pathological tissue mummifies, the scab darkens and falls off on its own after a few days. Healing occurs quickly. Complications (in the form of secondary infection or scarring) are rare. The development of systemic effects is unlikely.
Use of the drug Solcoderm
Treatment should be carried out by a doctor or specially trained medical personnel. Due to the instability of the solution in an open ampoule, a new ampoule must be used for each application. An open ampoule can be secured in a special recess in the package. Before the procedure, the affected area of skin is treated with alcohol or ether. Solcoderm is applied directly to the affected area of the skin. To apply the drug, each package contains an applicator with sharp and blunt ends and a glass tube. The sharp end of the applicator is intended for treating small lesions, the blunt end is intended for treating large and/or keratinized lesions. Using a glass tube, you can treat surfaces up to 4–5 cm2 in area. For adults and children, Solcoderm is carefully applied to the affected area with an applicator or glass tube and then penetrated with a plastic applicator until the solution is completely absorbed. Over the next 3–5 minutes, you need to pay attention to the appearance of a grayish or yellowish color of the treated skin. If necessary, the procedure should be repeated until the indicated color appears. Affected areas near mucous membranes and eyes should be treated with extreme caution. When treating keratinized warts, part of the stratum corneum can be previously removed. New growths with a diameter of 10 mm are treated with Solcoderm only if only the top layer of skin is affected. In case of multiple lesions, treatment with the drug must be carried out in several stages with an interval of about 4 weeks. In one session, 4–5 skin tumors with a total area of no more than 4–5 cm2 can be treated. Within a few days after treatment, the affected area is covered with a mummified dark brown scab. If mummification is unsatisfactory, the treatment can be repeated after a few days.
Solcoderm solution for external use in ampoules 0.2 ml No. 1
Name
Solcoderm.
Description
Transparent colorless solution.
Release form
0.2 ml - colorless glass ampoules (1) complete with a plastic applicator (1) and glass capillaries (2) - contour cell packaging (1) - cardboard packs.
pharmachologic effect
A drug for the local treatment of benign superficial skin lesions. The complex effect of Solcoderm components on the affected area of the skin ensures direct intravital fixation followed by mummification of the pathologically altered tissue with which the drug comes into contact. The immediate effect of the drug is expressed in skin discoloration with the appearance of a characteristic pale gray or yellowish tint. The tissue devitalized after exposure to the drug is dehydrated and, as it mummifies, acquires a dark brown color. The resulting mummified scab sloughs off spontaneously after a few days or weeks. Healing occurs quickly; complications such as secondary infection or scar tissue are rare
Pharmacokinetics
When using Solcoderm, no significant absorption of the active substance through the skin is observed; Due to the minimal volume of the therapeutic dose, the drug does not have a systemic effect on the body.
Indications for use
For external use in the treatment of benign skin changes: common warts (Verruca vulgaris); plantar warts (Verruca plantaris); genital warts (Condylomata acuminata); non-cellular nevus, tested for benignity (Naevus naevo-cellularis).
Directions for use and doses
Solcoderm is for external use only; The procedure must be performed by a physician or qualified medical personnel under the supervision of a physician. Before the procedure, the area of the affected skin is treated with ethyl alcohol or ether. Solcoderm is applied directly to the affected area of the skin. To apply the drug to the skin, use a special plastic applicator with sharp and blunt ends, available in the package. The sharp edge is used mainly for applying the drug to small affected areas of the skin; The blunt end is used to treat large lesions. As an alternative method of applying the drug, the supplied glass capillary is used. Combined skin lesions with an area of 2-3 cm2 can also be treated using a glass capillary. To fill a glass capillary with the drug, it must be immersed in Solcoderm solution for several minutes. Particular care should be taken during application, avoiding applying too large volumes of Solcoderm solution and damaging the deep layers of tissue. It is necessary to apply as much solution as the tissue of the affected skin area absorbs. Solcoderm is carefully applied to the affected area of skin with a plastic applicator or glass capillary and then distributed over the surface of the selected area of skin with light pressure using a plastic applicator until the solution completely penetrates the tissue. Over the next 3-5 minutes, it is necessary to carefully observe the changes occurring in the treated area: skin discoloration occurs with the appearance of a characteristic pale grayish or yellowish tint. The procedure should be repeated until the above changes in skin color occur. When treating keratinized warts, the top layer of the stratum corneum should first be removed. Affected areas of skin with a diameter of more than 10 mm are treated with Solcoderm only if it is established that only the top layer of skin is pathologically modified. In the presence of numerous foci of skin lesions, treatment with Solcoderm should be carried out in several stages, with an interval of approximately 4 weeks. During each procedure, no more than 2-3 lesions with a total area of no more than 2-3 cm2 can be treated. Within a few days after the procedure, the treated area of skin becomes dark brown and dries out to form a scab. In case of unsatisfactory mummification of pathologically altered tissue, the procedure can be repeated after a few days. In order to promote fixation and mummification of pathologically altered tissues that have undergone treatment, the affected areas should be treated 2-3 times a day with a swab moistened with a 70% solution of ethyl alcohol (especially after taking a bath or after washing). Do not remove the scab by scraping or using mechanical means. The scab must fall off spontaneously, otherwise tissue healing processes may be disrupted and scars may form.
Use during pregnancy and lactation
Studies to study the possible effect of the drug on the body of women during pregnancy and lactation have not been conducted to date. Solcoderm can be used during pregnancy and lactation only in cases where the potential benefits of its use outweigh the possible risk to the fetus or child.
Precautionary measures
Solcoderm is a strong acidic solution and has a damaging effect on nerve endings. The use of the drug on inflamed areas of the skin is not allowed. In cases of pain, treatment should be interrupted immediately. Using too large doses of the drug can lead to acid burns and damage to deep layers of tissue. Special precautions should be taken when applying the drug solution to the face, especially to the skin areas located near the eyes. If accidental contact of the drug with healthy skin occurs, it should be immediately removed using a cotton swab moistened with water. If Solcoderm accidentally comes into contact with the eyes, it is necessary to immediately rinse the eye with a large amount of water or with a weak alkaline solution, for example, 1% sodium bicarbonate solution. Drops of Solcoderm solution that get on furniture or clothing must be washed off with water, since the drug can destroy the materials from which they are made. After a biopsy of the affected skin area, it is recommended to wait 8-10 days before starting treatment with the drug solution. The application of an occlusive dressing during treatment is not recommended. Treatment for careless ingestion corresponds to general measures for acid poisoning: drink plenty of water as quickly as possible and go to the clinic. Special care is required when treating benign skin tumors with Solcoderm that have previously been treated with other drugs or other methods. Disposal of used ampoules: before discarding the ampoule, the remaining solution should be washed off in running water. The empty ampoule can be thrown into a waste container.
Interaction with other drugs
The interaction of Solcoderm with other topical medications has not been established.
Contraindications
Compound
1 ml of solution contains Active ingredients: Nitric acid 70% Glacial acetic acid Oxalic acid dihydrate Lactic acid 90% Copper (II) nitrate trihydrate Excipient: Purified water
Overdose
An ulcer resulting from an overdose is treated like a regular wound.
Side effect
In cases of improper use of Solcoderm (use of too large doses), deep layers of tissue may be damaged. Treatment with Solcoderm is often associated with a short-term burning sensation at the site of application of the drug, which usually lasts for several minutes. If severe local irritation and severe itching occur in adjacent areas of the skin, it is recommended to use a cream containing steroid components or an ointment that has an anesthetic effect. The use of Solcoderm can lead to changes in skin pigmentation and the formation of scar tissue. However, provided that the healing process proceeds normally, is not accompanied by infection, and the resulting eschar disappears spontaneously, the risk of such undesirable effects is negligible.
Storage conditions
Store at a temperature not exceeding 25 °C. Keep out of the reach of children! Handle with care!
Buy Solcoderm solution for external use in amp. 0.2 ml in pack No. 1 with set of plastic app. (1 pcs.) and glass cups (2 pcs.) in the pharmacy
Price for Solcoderm solution for external use in amp. 0.2 ml in pack No. 1 with set of plastic app. (1 pcs.) and glass capillaries (2 pcs.)
Instructions for use for Solcoderm solution for external use in amp. 0.2 ml in pack No. 1 with set of plastic app. (1 pcs.) and glass capillaries (2 pcs.)
Special instructions for the use of Solcoderm
For the normal course of the mummification process, the neoplasm on which Solcoderm is applied should be treated with 70% alcohol, especially after taking a bath/shower. The scab cannot be removed; it must fall off on its own. Until complete healing, direct exposure to sunlight and UV irradiation should be avoided. If the drug gets on mucous membranes or healthy skin, it must be quickly washed off with plenty of water or 1% sodium bicarbonate solution. When surgically removing the affected area of skin prior to using Solcoderm, treatment should begin no earlier than 8–10 days later. Patients with a tendency to form rough scars should not be prescribed Solcoderm. Treatment with Solcoderm during pregnancy is carried out only in cases where the benefit to the mother outweighs the risk to the fetus. Before discarding used ampoules, any remaining solution should be washed off with running water.
Instructions for use SOLCODERM (SOLCODERM)
Solcoderm is for external use only; The procedure must be performed by a physician or qualified medical personnel under the supervision of a physician.
Before the procedure, the area of skin to be treated is first disinfected with ethanol or ether. Solcoderm is applied directly to the affected area of the skin. To apply the drug to the skin, use a special plastic applicator included in the package with a beveled edge on one side and a blunt edge (spatula) on the other. The end with a beveled edge is used mainly for applying the drug to small affected areas of the skin; spatula - for treating large lesions.
As an alternative method of applying the drug, the supplied glass capillary is used. Combined skin lesions with an area of 2-3 cm2 can also be treated using a glass capillary. To fill a glass capillary with the drug, it must be immersed in Solcoderm solution for several minutes. Particular care should be taken during application, avoiding applying too large volumes of Solcoderm solution and damaging the deep layers of tissue.
Solcoderm is carefully applied to the affected area of skin with a plastic applicator or glass capillary and then evenly distributed over the surface of the selected area of skin using a plastic applicator, while lightly pressing the applicator to completely penetrate the solution into the tissue. Over the next 3-5 minutes, it is necessary to carefully observe the changes occurring in the treated area:
- discoloration of the skin occurs with the appearance of a characteristic pale grayish or yellowish tint. The procedure should be repeated until skin discoloration occurs.
When treating affected areas of the skin located next to the mucous membranes, incl. near the eyes, special precautions should be taken.
When treating deep keratinized areas of the skin, the top layer must first be removed.
Affected areas of skin with a diameter of more than 10 mm are treated with Solcoderm only if it is established that only the top layer of skin is pathologically modified.
In the presence of numerous foci of skin lesions, treatment with Solcoderm should be carried out in several stages, with an interval of approximately 4 weeks. During each procedure, no more than 2-3 lesions with a total area of no more than 2-3 cm2 can be treated.
During the procedure, mild transient erythema and the formation of a pale ring may be observed on the normal skin surrounding the treated area (due to vascular contraction). Such phenomena are normal and do not require special therapy. If pain occurs, treatment is stopped immediately. A few days after the procedure, a dark brown scab forms on the treated area of skin. In case of insufficient mummification of the pathologically altered tissue, the procedure can be repeated after a few days.
In order to promote fixation and mummification of pathologically altered tissues, the affected areas should be treated 2-3 times a day with a swab moistened with a 70% ethanol solution (especially after taking a bath or after washing).
Do not remove the scab by scraping or using mechanical means. The scab must fall off spontaneously, otherwise tissue healing processes may be disrupted and scars may form.
Until complete healing of the lesion is achieved (approximately 2-4 months after therapy), exposure to direct sunlight and UV irradiation should be avoided.
After opening the ampoule, the solution is chemically unstable; a new ampoule must be used for each therapeutic procedure. The tip of the ampoule breaks off along the mark. The opened ampoule should be stored strictly vertically in a plastic packaging holder.
