What is Grammidin
A pharmaceutical product based on the antimicrobial substance gramicidin C is used to eliminate the symptoms of acute respiratory infections, tonsillitis and other infectious lesions of the oropharynx and trachea.
The Grammidin line combines several drugs with similar effects. They are produced in the form of rounded flat candies of yellowish or white color, packed in cell plates.
- Grammidin: mint flavor;
- Grammidin Neo with anesthetic (lidocaine);
- children's Grammidin: with the taste and aroma of raspberries.
The composition of the drug Grammidin Neo also includes oxybuprocaine and cetylpyridinium, which have an additional antiseptic effect.
Among the excipients of the drug: sugar, calcium stearate and formative additives. Each type of drug has a characteristic packaging with a painted scarf. The medicine is also produced in liquid form: in the form of a spray in pediatric and adult dosages.
Grammidin with Anesthetic Neo tablets d/rassas No. 18
Compound
Active substances:
1 tab. | |
gramicidin C dihydrochloride | 3.2 mg, |
which corresponds to the content of gramicidin | 3 mg |
Oxybuprocaine hydrochloride | 0.2 mg |
cetylpyridinium chloride monohydrate | 1.05 mg, |
which corresponds to the content of cetylpyridinium chloride | 1 mg |
Excipients: colloidal silicon dioxide - 5 mg, talc - 60 mg, acesulfame potassium - 15 mg, mint flavor - 25 mg, sorbitol - 1065.55 mg, magnesium stearate - 25 mg.
Indications for use
Infectious and inflammatory diseases of the mouth and throat: sore throat, pharyngitis, tonsillitis, periodontal disease, gingivitis, stomatitis.
Contraindications
- Hypersensitivity to the components included in the drug;
- children under 4 years of age;
- pregnancy (first trimester).
Directions for use and doses
It is used after meals, by dissolving in the mouth without chewing.
Immediately after using the drug, you should refrain from eating and drinking for 1-2 hours.
Dosage for adults and children over 12 years of age: 1 tablet 3-4 times a day.
Dosage for children from 4 to 12 years: 1 tablet 1-2 times a day.
If there is no therapeutic effect within 7 days of taking the drug, it is recommended to consult a doctor.
Storage conditions
In a place protected from light at a temperature not exceeding 25° C. Keep out of the reach of children.
Best before date
2 years. Do not use after expiration date
special instructions
If there is no therapeutic effect within 7 days, the patient should consult a doctor.
Description
Antibiotic + antiseptic + local anesthetic.
Use in children
Contraindication: children under 4 years of age.
Pharmacodynamics
Combined drug for the treatment of infectious and inflammatory diseases of the pharynx and oral cavity. The drug contains the antimicrobial agent gramicidin C, the local anesthetic agent oxybuprocaine and the antiseptic agent cetylpyridinium chloride.
The mechanism of action of gramicidin C is associated with an increase in the permeability of the cytoplasmic membrane of the microbial cell, which disrupts its stability and causes cell death.
Gramicidin C has a pronounced antimicrobial effect against pathogens of infectious diseases of the oral cavity and pharynx.
The anesthetic oxybuprocaine has a local anesthetic effect on the mucous membrane of the oral cavity and pharynx. Causes a reversible blockade of the propagation and conduction of nerve impulses through the axons of nerve cells.
Cetylpyridinium chloride is an antiseptic. Suppresses the growth and reproduction of pathogens of infectious diseases of the oral cavity.
The drug has an analgesic effect, reduces inflammation, has an antimicrobial effect, softens discomfort in the throat, facilitates swallowing, and when absorbed causes hypersalivation, which contributes to the mechanical cleansing of the oral cavity and pharynx from microorganisms.
Side effects
In some cases: allergic reactions, temporary loss of sensitivity of the tongue.
Use during pregnancy and breastfeeding
It is not recommended to use the drug during pregnancy (I) trimester. Breastfeeding should be stopped while taking the drug.
Interaction
Grammidin® with neo anesthetic enhances the effects of other antimicrobial agents of local and systemic action.
Release form
Lozenges.
How does Grammidin work?
The active substance of the drug violates the integrity of the membranes of bacterial cells, provoking their destruction. Grammidin has a local antiseptic effect in the oral cavity, slows down the proliferation of pathogens and stimulates the secretion of saliva, which softens inflamed mucous membranes. As a result of several applications, pain and swelling are reduced, swallowing becomes easier, and normal health is restored. The effectiveness of the drug is higher with initial signs of infection.
Grammidin with an anesthetic has an additional analgesic effect, smoothing out acute symptoms of inflammation. Gramicidin is not absorbed into the general bloodstream, so one should not expect a systemic effect from the drug.
Buy Grammidin neo with anesthetic lozenges No. 18 in pharmacies
Grammidin with anesthetic neo Buy Grammidin with anesthetic neo in pharmacies DOSAGE FORMS lozenges 3mg+0 2mg+1mg
MANUFACTURERS Valenta Pharmaceuticals (Russia)
GROUP Combined antibiotics
COMPOSITION Gramicidin C, oxybuprocaine, cetylpyridinium chloride.
INTERNATIONAL NON-PROPENTED NAME Gramicidin C + Oxybuprocaine + Cetylpyridinium chloride
PHARMACOLOGICAL ACTION Antibacterial combined drug for local use in the oral cavity and pharynx. The drug contains the antibiotic gramicidin C, the local anesthetic oxybuprocaine and the antiseptic cetylpyridinium chloride. The drug has a pronounced antibacterial effect against pathogens of infectious and inflammatory diseases of the pharynx and oral cavity. Increases the permeability of the microbial cell membrane, which disrupts its barrier functions and leads to its death. The anesthetic oxybuprocaine, causing a reversible block of axonal conduction of nerve impulses, has an analgesic effect on the mucous membrane of the oral cavity and pharynx. Cetylpyridinium chloride, being an antiseptic, inhibits the growth and reproduction of pathogens of infectious diseases of the oral cavity. The drug has antimicrobial, analgesic and anti-inflammatory effects, reduces discomfort in the oral cavity and pharynx, and facilitates the swallowing process. When absorbed, the drug stimulates hypersalivation, which promotes mechanical cleansing of the oral cavity and pharynx from microorganisms. The drug has a local effect.
INDICATIONS FOR USE Infectious and inflammatory diseases of the oral cavity and pharynx: sore throat, pharyngitis, tonsillitis, periodontal disease, gingivitis, stomatitis.
CONTRAINDICATIONS First trimester of pregnancy, children under 4 years of age, hypersensitivity to the components of the drug.
SIDE EFFECTS In some cases: allergic reactions, temporary loss of sensitivity of the tongue.
INTERACTION The drug, when taken together, increases the effectiveness of other antimicrobial agents of local and systemic action.
METHOD OF APPLICATION AND DOSAGE For adults and children over 12 years of age, the drug is prescribed 1 tablet 3-4 times a day; children aged 4 to 12 years - 1 tablet 1-2 times a day. The tablets are used after meals, dissolving in the mouth without chewing. Immediately after using the drug, you should refrain from eating and drinking for 1-2 hours. If there is no therapeutic effect within 7 days of taking the drug, the patient should consult a doctor.
OVERDOSE No data available.
SPECIAL INSTRUCTIONS No data available.
STORAGE CONDITIONS Store out of reach of children, in a dry place, protected from light at a temperature not exceeding 25 degrees. WITH.
Contraindications for use
It is necessary to stop using the drug:
- people with galactose intolerance or malabsorption syndrome;
- patients with phenylketonuria;
- those suffering from individual hypersensitivity to any component;
- having open injuries to the mucous membranes of the mouth and larynx.
Caution Grammidin tablets should be used for diabetes, as it contains sugar.
What diseases does Grammidin help with?
The drug is prescribed for the treatment of bacterial diseases of the throat and oral cavity, accompanied by inflammatory processes:
- pharyngitis - damage to the mucous and lymphoid tissue of the pharynx;
- tonsillitis - infection of the mucous membrane, inflammation of the annular part, tonsils;
- tonsillitis - damage to the palatine tonsils;
- stomatitis – ulcerative formations in the oral cavity, damage to the mucous membrane;
- gingivitis – inflammatory processes in the gum tissue;
- periodontitis is inflammation of the bone and soft tissues of the tooth.
The medicinal effect is based on the destruction of bacteria that cause diseases. This leads to inhibition of inflammatory processes and a decrease in pain symptoms in the throat, which makes swallowing easier.
How to use Grammidin
The drug is approved for treatment from 4 years of age. It is dissolved in the mouth after eating like a candy, without chewing, until completely dissolved:
- patients under 12 years old: 1 pc. 2 times a day;
- from 12 years and older: 2 pcs. up to 4 times a day;
- course of therapy: 5–6 days.
To ensure that the active substance remains on the mucous membranes for as long as possible, after taking the medicine you should not drink or eat food for 1 hour. Otherwise, Grammidin will not have any effect.
Grammidin spray 0.06 mg+0.1 mg/dose 112 doses
A country
Netherlands, Russia
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.
Compound
Bottle of 112 doses of Gramicidin C dihydrochloride 0.0638 mg, cetylpyridinium chloride 0.1 mg. Excipients: ethanol 96% - 19 mg, sucralose - 0.2 mg, glycerol - 33.2 mg, mint flavor - 0.82 mg, citric acid monohydrate - 0.058 mg, sodium citrate - 0. 022 mg, polysorbate 80 - 0.4 mg, methyl parahydroxybenzoate (methylparaben) - 0.184 mg, propyl parahydroxybenzoate (propylparaben) - 0.02 mg, purified water - up to 0.2 ml. Spray for topical use dosed in the form of a clear or opalescent, colorless or yellowish solution with a characteristic mint odor .
pharmachologic effect
Antibiotic + antiseptic.
Indications for use
Infectious and inflammatory diseases of the mouth and throat: pharyngitis, tonsillitis, periodontitis, gingivitis, stomatitis.
Mode of application
Locally, by spraying onto the mucous membrane of the mouth and throat. Used after meals. Dosage for adults: 4 injections per application 3 times a day for 7 days. Immediately after using the drug, you should refrain from eating and drinking for 1 hour. If after treatment there is no improvement or the symptoms worsen, or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, the method of use and the doses which are indicated in the instructions.
Side effect
Allergic reactions to the components of the drug are possible. If you experience the side effects indicated in the instructions, or they get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Contraindications
- hypersensitivity to gramicidin C, cetylpyridinium chloride and other components of the drug; - pregnancy (I trimester); - lactation period; - children under 18 years of age. With caution: pregnancy (II-III trimester).
special instructions
The drug should not be used if there are open wounds in the oral cavity, since cetylpyridinium chloride slows down wound healing. The drug contains ethanol. In the maximum single dose of the drug, the ethanol content is up to 0.08 g. Effect on the ability to drive transport. Wed and fur.: The drug does not affect the ability to perform potentially hazardous activities that require special attention and speed of reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher and operator, etc.).
Is Grammidin safe for pregnant women and breastfeeding?
Grammidin cannot be used in the first trimester, as its components may be toxic to the tissues of the embryo. In exceptional cases, with severe inflammation of the gums or throat, you can use children's tablets or spray. But only with the prior permission of the doctor.
In the second and third trimester, pregnancy is not a contraindication for Grammidin. But self-medication should not be allowed.
Breastfeeding women are not recommended to use the drug, as the risk of it passing into breast milk cannot be completely ruled out. If treatment is necessary, children should be transferred to mixed or artificial nutrition.
"Grammidin": description, types, composition
"Grammidin" is a medical product for the treatment of infections of the throat and mouth. It is produced in the form of a spray and tablets and is taken externally. The product contains 2 active ingredients:
- Gramicidin C dihydrochloride is an antibiotic that has an antibacterial effect (impairs the permeability of bacterial cell membranes).
- Cetylpyridinium chloride is an antiseptic that destroys microorganisms and suppresses colony reproduction.
Today they produce 5 forms of the drug - this is “Grammidin”:
- for children;
- for children (in the form of a spray);
- Neo;
- with anesthetic Neo;
- in the form of a spray.
The active ingredients are the same in all cases.
Restrictions and contraindications
Preparations from the Grammidin line are contraindicated:
- children up to 3 years old inclusive;
- individual intolerance, allergic reactions;
- phenylketonuria;
- open, bleeding wounds in the mouth;
- pregnancy (1st trimester).
Restricted admission:
- pregnancy (II and III trimester) - only in consultation with a doctor;
- lactation - only with interrupted feeding.
Important!
"Grammidin for children" can also be used during the first trimester of pregnancy. In these products the concentration of active substances is reduced. Therefore, admission is possible, preferably in consultation with a doctor.