Magnesium B6 forte, 30 pcs., 100 mg, film-coated tablets
Magnesium takes part in more than 300 enzymatic reactions. It is needed for the production of protein, DNA, for the breakdown of glucose, the removal of toxins from the body, for the absorption of vitamin C, thiamine (B1) and pyridoxine (B6). Magnesium contributes to the stability of the cell structure during growth, takes part in the process of regeneration of body cells, has a beneficial effect on the functioning of internal organs, reduces irritability and protects against radiation. Vitamin B2 (riboflavin) helps convert vitamin B6 into its active form. With a lack of Vitamin B2, the absorption of iron decreases and the activity of the thyroid gland worsens. It has antioxidant properties, participates in metabolic processes and has a positive effect on the immune system, the state of the cardiovascular and nervous systems, skin and mucous membranes, liver function, stimulates hematopoiesis, and is responsible for the health of hair and nails. Vitamin B6 (pyridoxine hydrochloride) improves the absorption of magnesium from the gastrointestinal tract and its penetration into body cells, participates in the synthesis of hormones, as well as nucleic acids, which increase immunity and prevent the aging process. Magnesium and the female body Magnesium will help eliminate PMS symptoms. Premenstrual passion for chocolate is explained by a lack of magnesium in the body. "Magnesium B6 FORTE VITAMIR®" will help compensate for the lack of magnesium without adding calories to you.
Effect of Magnesium on the human body:
Magnesium and bones Today it has been proven that consuming the required amount of magnesium significantly increases bone mineral density. Moreover, as it turns out, magnesium is much more important than calcium for the health of our bones. Bone health depends not only on calcium, but it is clear that it depends just as much on magnesium. With the help of magnesium, cartilage and bone tissue grow, calcium and vitamins B, C, E are absorbed.
Magnesium and muscles Magnesium increases endurance. An experiment was conducted for a group of American athletes: before important competitions, they took magnesium. The results exceeded all expectations. In addition, complaints of chest pain that arose during intense training earlier have practically disappeared.
Magnesium and memory, emotions If you have increased anxiety, magnesium will help cope with stress. This trace element increases interest in new things, relieves some types of migraines, and improves memory.
Magnesium and the Heart Most patients with cardiovascular disease are deficient in magnesium. Patients who are being prepared for heart surgery are recommended to be prescribed magnesium to normalize blood pressure and minimize the possibility of heart rhythm disturbances and arrhythmias. Taking magnesium-containing medications as a preventive measure will help reduce the risk of cardiovascular disease.
Magnesium and figure Magnesium improves digestion, helps move food through the intestines, utilize proteins and fats, and stabilizes genes responsible for obesity. If your family has a tendency to be overweight, then in the presence of magnesium these genes will not open up. Magnesium reduces the level of “stress” hormones, saving you from overeating
Magne B6 forte for magnesium and vitamin B6 deficiency tablets No. 40
A country
Hungary
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.
Compound
1 tablet contains the core of the tablet: active ingredients: magnesium citrate - 618.43 mg, which corresponds to 100 mg of magnesium (Mg++), pyridoxine hydrochloride - 10.00 mg; excipients: lactose - 50.57 mg, macrogol-6000 - 120.00 mg, magnesium stearate - 1.00 mg. Tablet shell: hypromellose 6 mPa.s - 14.08 mg, macrogol-6000 - 1.17 mg, titanium dioxide (E 171) - 4.75 mg, talc - traces. Description Oval, biconvex, white film-coated tablets. At the fracture, two layers are visible: a white shell and a white tablet mass. Release form: Film-coated tablets. 15 or 20 tablets in a blister made of PVC-PE-PVDC/aluminum foil. 2 or 4 blisters of 15 tablets each, 2 or 3 blisters of 20 tablets each, along with instructions for use in a cardboard box.
Pharmacological properties
Pharmacodynamics Magnesium is a vital element that is necessary for the normal functioning of cells and is involved in most metabolic reactions. In particular, it is involved in the regulation of the transmission of nerve impulses and muscle contraction. 1/3 of the amount of magnesium contained in the body accumulates in bone tissue. The body receives magnesium through food. A lack of magnesium in the body can be observed when the diet is disrupted, when the need for magnesium increases, or when there is an imbalance in the intake, metabolism and excretion of magnesium (for example, with increased physical and mental stress, stress, during pregnancy, when using diuretics). Pyridoxine (vitamin B6) is involved in many metabolic processes and helps improve the absorption of magnesium from the gastrointestinal tract and its penetration into cells. Serum magnesium levels: - between 12 and 17 mg/L (1 - 1.4 mEq/L or 0.5 - 0.7 mmol/L): indicate mild magnesium deficiency; - below 12 mg/L (1 mEq/L or 0.5 mmol/L): indicate severe magnesium deficiency. Pharmacokinetics Gastrointestinal absorption of magnesium salts occurs partly through a passive mechanism in which the solubility of the salt plays a determining role. The degree of this absorption does not exceed 50%. Excretion occurs mainly by the kidneys.
Indications for use
Established magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as increased irritability, minor sleep disturbances, gastrointestinal cramps, rapid heartbeat, increased fatigue, muscle pain and spasms, and a tingling sensation in the muscles. If after a month of treatment there is no improvement in these symptoms, continuing treatment is not advisable.
Contraindications
Hypersensitivity to any of the components of the drug. Severe renal failure (creatinine clearance less than 30 ml/min). Phenylketonuria. Age up to 6 years (efficacy and safety have not been established). Hereditary galactosemia, glucose and galactose malabsorption syndrome, or lactase deficiency (due to the presence of lactose in the drug). Concomitant use of levodopa (see “Interaction with other drugs”). With caution: Moderate renal failure (risk of developing hypermagnesemia). Use during pregnancy and breastfeeding Pregnancy Clinical experience with the drug in a sufficient number of pregnant women has not revealed any adverse effects on the occurrence of fetal malformations or fetotoxic effects. The drug Magne B6® forte can be used during pregnancy only if necessary, on the recommendation of a doctor. Breastfeeding period Taking into account that magnesium passes into breast milk, if it is necessary to take the drug, it is recommended to stop breastfeeding.
Mode of application
The tablets should be taken whole with a glass of water. Adults: 3-4 tablets per day, divided into 2-3 doses, with meals. Children over 6 years of age (weighing about 20 kg): 10-30 mg/kg/day (0.4–1.2 mmol/kg/day), i.e. children over 6 years of age (weighing about 20 kg) 2- 4 tablets per day, divided into 2-3 doses, with meals. Typically the duration of treatment is one month.
Side effect
Immune system disorders: Very rare (Gastrointestinal disorders: Unknown frequency (it is not possible to estimate the frequency of occurrence based on available data): diarrhea, abdominal pain, nausea, vomiting, flatulence.
Overdose
Symptoms With normal renal function, an overdose of magnesium when taken orally does not usually lead to toxic reactions. However, in case of renal failure, magnesium poisoning may develop. Symptoms of overdose, the severity of which depends on the concentration of magnesium in the blood: decreased blood pressure; nausea, vomiting; depression of the central nervous system, decreased reflexes; changes in the electrocardiogram; respiratory depression, coma, cardiac arrest and respiratory paralysis; anuric syndrome. Treatment Rehydration, forced diuresis. In case of renal failure, hemodialysis or peritoneal dialysis is necessary.
Interaction
Contraindicated combinations With levodopa: the activity of levodopa is inhibited by pyridoxine (unless taking this drug is combined with taking inhibitors of peripheral aromatic L-amino acid decarboxylase). Any amount of pyridoxine should be avoided unless levodopa is taken in combination with peripheral aromatic L amino acid decarboxylase inhibitors. Not recommended combinations The simultaneous use of drugs containing phosphates or calcium salts may impair the absorption of magnesium in the intestine. Combinations that should be taken into account When prescribing tetracyclines orally, it is necessary to maintain an interval of at least three hours between ingestion of tetracycline and Magne B6 forte, since magnesium preparations reduce the absorption of tetracyclines.
special instructions
The tablets are intended only for adults and children over 6 years of age. In case of moderate renal failure, the drug should be taken with caution due to the risk of developing hypermagnesemia. If calcium and magnesium are deficient at the same time, the magnesium deficiency should be corrected before taking calcium supplements or dietary supplements containing calcium. When pyridoxine is used in high doses (more than 200 mg per day) for a long time (over several months or in some cases years), sensory axonal neuropathy may develop, which is accompanied by symptoms such as numbness and impaired proprioceptive sensitivity, distal tremor limbs and gradually developing sensory ataxia (impaired coordination of movements). These disorders are usually reversible and disappear after stopping taking vitamin B6. Impact on the ability to drive vehicles and engage in other potentially hazardous activities No effect. There are no special recommendations.
Magne B6 Forte PPO tablets No. 40
Compound
Active ingredients: magnesium 100 mg, pyridoxine hydrochloride 10 mg.
Pharmacokinetics
Gastrointestinal absorption of magnesium salts occurs partly through a passive mechanism in which the solubility of the salt plays a determining role. The degree of this absorption does not exceed 50%.
It is excreted primarily by the kidneys.
Indications for use
Established magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as:
- increased irritability;
- minor sleep disturbances;
- gastrointestinal cramps or rapid heartbeat;
- increased fatigue;
- pain and muscle spasms;
- tingling sensation.
Contraindications
- hypersensitivity to the components of the drug;
- severe renal failure (creatinine clearance <30 ml/min);
- age up to 6 years (efficacy and safety have not been established);
- hereditary galactosemia, glucose and galactose malabsorption syndrome or lactase deficiency (due to the presence of lactose in the drug);
- simultaneous administration of levodopa.
With caution: moderate renal failure (risk of developing hypermagnesemia).
Directions for use and doses
The drug is taken orally with meals. The tablets should be taken whole with a glass of water.
Adults are recommended to take 3-4 tablets/day.
Children over 6 years of age (with a body weight of about 20 kg) - 10-30 mg/kg/day (0.4-1.2 mmol/kg/day), i.e. 2-4 tablets/day.
The daily dose should be divided into 2-3 doses.
Typically the duration of treatment is 1 month.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 30°C.
Best before date
2 years.
special instructions
The tablets are intended only for adults and children over 6 years of age.
In case of moderate renal failure, the drug should be taken with caution due to the risk of developing hypermagnesemia.
If calcium and magnesium deficiency occur simultaneously, the magnesium deficiency should be corrected before taking calcium supplements or dietary supplements containing calcium.
When using pyridoxine in high doses (more than 200 mg/day) for a long time (over several months or in some cases years), sensory axonal neuropathy may develop, which is accompanied by symptoms such as numbness and impaired proprioceptive sensitivity, distal tremor limbs and gradually developing sensory ataxia (impaired coordination of movements). These disorders are usually reversible and disappear after stopping vitamin B6.
Dosage form
White film-coated tablets, oval, biconvex; two layers are visible on the fracture: a white shell and a white tablet mass.
Use in children
Use in children under 6 years of age: efficacy and safety have not been established.
Action
Magnesium is a vital element that is found in all tissues of the body and is necessary for the normal functioning of cells and is involved in most metabolic reactions. In particular, it is involved in the regulation of the transmission of nerve impulses and muscle contraction.
The body receives magnesium through food. A lack of magnesium in the body can be observed when the diet is disrupted, when the need for magnesium increases, or when there is an imbalance in the intake, metabolism and excretion of magnesium (for example, with increased physical and mental stress, stress, during pregnancy, when using diuretics).
Pyridoxine (vitamin B6) is involved in many metabolic processes and in the regulation of nervous system metabolism. Vitamin B6 improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.
Serum magnesium content:
- from 12 to 17 mg/l (0.5-0.7 mmol/l) - moderate magnesium deficiency;
- below 12 mg/l (0.5 mmol/l) – severe magnesium deficiency.
Side effects
From the immune system: very rarely (<0.01%) - allergic reactions, including skin reactions.
From the digestive system: frequency unknown (it is not possible to estimate the frequency of occurrence based on available data) - diarrhea, abdominal pain, nausea, vomiting, flatulence.
Use during pregnancy and breastfeeding
Pregnancy
Clinical experience with the use of the drug in a sufficient number of pregnant women has not revealed any adverse effects on the occurrence of fetal malformations or fetotoxic effects.
Magne B6® Forte can be used during pregnancy only if necessary, on the recommendation of a doctor.
Breastfeeding period
Taking into account that magnesium passes into breast milk, if it is necessary to take the drug during lactation, it is recommended to stop breastfeeding.
Interaction
Contraindicated combinations
With levodopa: the activity of levodopa is inhibited by pyridoxine (unless this drug is combined with the use of peripheral aromatic L-amino acid decarboxylase inhibitors). Any amount of pyridoxine should be avoided unless levodopa is taken in combination with peripheral aromatic L-amino acid decarboxylase inhibitors.
Combinations not recommended
The simultaneous use of drugs containing phosphates or calcium salts may impair the absorption of magnesium in the intestine.
Combinations to Consider
When using antibiotics of the tetracycline group, it is necessary to maintain an interval of at least 3 hours between oral administration of tetracycline and Magne B6® forte, because Magnesium preparations reduce the absorption of tetracyclines.
Overdose
With normal renal function, an overdose of magnesium taken orally does not usually lead to toxic reactions. However, in case of renal failure, magnesium poisoning may develop. The severity of symptoms depends on the concentration of magnesium in the blood.
Symptoms: decreased blood pressure, nausea, vomiting, central nervous system depression, decreased reflexes, ECG changes, respiratory depression, coma, cardiac arrest and respiratory paralysis, anuric syndrome.
Treatment: rehydration, forced diuresis. In case of renal failure, hemodialysis or peritoneal dialysis is necessary.
Release form
Film-coated tablets, No. 40.
Impact on the ability to drive vehicles and operate machinery
Does not affect. There are no special recommendations.
