Instructions for use FURAGIN

Pharmacodynamics and pharmacokinetics

The drug affects many gram-positive and gram-negative microorganisms. Its therapeutic effect is due to the fact that the drug belongs to nitrofurans and includes a molecule that can bind to biologically active substances in microbial cells that can transfer a hydrogen molecule. This prevents further activity of the microbial cell.

To achieve a positive result, the active substance of the drug in a small concentration is sufficient.

The drug is absorbed in the intestine through passive diffusion. When taken orally, it has a disinfecting effect on the kidneys, urethra, and bladder. The drug is excreted by the kidneys.

On forums you can often come across the question, is Furagin an antibiotic or not? This medicine is an antibacterial and antimicrobial drug. Unlike many antibiotics, it does not have a systemic effect. The drug is intended for topical use and cannot in any way be classified as a systemic antibiotic .

Pharmacological properties of the drug Furagin

Furagin belongs to the group of antimicrobial agents - nitrofuran derivatives that have a wide spectrum of antimicrobial action. Effective against gram-positive and gram-negative bacteria; in some cases it is effective against microorganisms resistant to sulfonamides and antibiotics. The mechanism of the antimicrobial action of the drug is associated with the reduction of the nitro group to the amino group. In this case, the reduced forms of the drug have a direct effect on cellular macromolecules and electron transport in the microbial cell. Interacting at the DNA level, it causes breaks and mutations in it, which leads to disruption of its biological function. It is also assumed that the reduced form of the drug oxidizes a number of enzyme systems of microorganisms. Regarding some microorganisms, the antimicrobial effect of Furagin is higher than that of other nitrofurans. The drug is especially active against urinary tract infections.

Indications for use of Furagin

Indications for use of Furagin:

• preventing the occurrence of an infectious process during the treatment of recurrent diseases;
• infectious and inflammatory diseases of the genitourinary system.

Specialists can prescribe Furagin for cystitis , prostatitis , pyelonephritis , urethritis , including after operations.

In addition, in pharmacies you can find such a remedy as Furagin Lect. It also has antimicrobial effects.

Indications for use of Furagin Lect:

• infections of the skin and soft tissues;
• urogenital infections;
• prophylaxis during urological operations ;
• gynecological infections;
• infectious and inflammatory diseases of the mouth and pharynx;
• severe infected burns ;
• infected wounds.

Contraindications

You cannot use Furagin tablets for cystitis and other infectious and inflammatory diseases of the genitourinary system if the body has a negative reaction to the drug and kidney failure .

In addition, this remedy is contraindicated in the following cases:

• congenital enzymatic deficiency of glucose-6-phosphate dehydrogenase ;
• if the patient is less than a week old;
• allergies to drugs belonging to the nitrofuran ;
• multiple lesions of peripheral nerves .

Furagin is not used during pregnancy and lactation .

Interactions of the drug Furagin

When used simultaneously with drugs of the tetracycline group, there is a potentiation of the effects of the drug, in combination with erythromycin, fusidine, nystatin, levorin - an increase in the effect; with ristomycin, chloramphenicol, polymyxins, long- and short-acting sulfonamides, nalidixic acid - mutual reduction of effect. Antacids reduce the activity of the drug by reducing its absorption. With the simultaneous use of nitrofuran derivatives with 8-hydroxyquinoline nitroxoline, the neurotoxic effect of these drugs is summed up. The drug should not be used with adrenergic agonists (ephedrine, phenamine), anorexigenic drugs, or MAO inhibitors.

Side effects

The following side effects are possible when taking tablets:

• gastrointestinal tract: loss of appetite , upset stool, pain in the abdomen, vomiting, nausea;
• allergies: skin itching , rash;
• CNS: dizziness , neuritis , blurred vision, drowsiness , multiple lesions of peripheral nerves .

In addition, malaise , increased body temperature, and chills .

Instructions for use FURAGIN

The drug is usually well tolerated, but side effects are possible.

The incidence of adverse drug reactions is the percentage of the number of patients who experienced an adverse reaction to a drug at a given time to the total number of patients who used that drug at a certain time.

Adverse reactions are listed according to systemic organ classes, in descending order of frequency. Criteria for the incidence of adverse reactions:

• over 10% - very frequent;
• 1-10% - frequent;
• 0.1-1% - infrequent;
• 0.01-0.1% - rare;
• less than 0.01% - very rare.

Blood and lymphatic system disorders:

very rare - hematopoietic disorders (agranulocytosis, thrombocytopenia, aplastic anemia).

Nervous system disorders:

Uncommon: dizziness, drowsiness, blurred vision;

• rare - peripheral neuropathy;
• very rare - mild intracranial hypertension.

Disorders of the respiratory system, chest and mediastinal organs:

rare - acute and chronic pulmonary reactions. An acute pulmonary reaction develops rapidly. It is manifested by severe shortness of breath, fever, chest pain, cough with or without sputum, eosinophilia (increased number of eosinophilic granulocytes in the blood). There is information about the simultaneous appearance of skin rashes, itching, urticaria, myalgia (muscle pain), and angioedema (swelling of the face, neck, oral tissues and larynx) with an acute pulmonary reaction. The basis of an acute pulmonary reaction is a hypersensitivity reaction that can develop over several hours, less often within minutes. The acute pulmonary reaction is reversible and disappears when the drug is stopped. A chronic pulmonary reaction can develop over a long period of time after stopping treatment with nitrofurans (including furagin). Characterized by a gradual increase in dyspnea, tachypnea, unstable fever, eosinophilia, progressive cough and interstitial pneumonitis and/or pulmonary fibrosis.

Gastrointestinal disorders:

infrequently - loss of appetite, nausea;

• rare - vomiting, diarrhea;
• very rare - pancreatitis (inflammation of the pancreas).

Disorders of the skin and subcutaneous tissues:

rare - papular rash, itching, transient hair loss;

• very rare - angioedema, urticaria, dermatitis, Erythemamultiforme.

Musculoskeletal and connective tissue disorders:

very rare - arthralgia (joint pain).

General violations:

rare - weakness, increased body temperature.

Disorders of the liver and biliary tract:

very rare - cholestatic jaundice, hepatitis.

Furagin turns urine brown.

Read also:  Luteinizing hormone and features of its determination

Side effects are reduced if the drug is taken after meals with plenty of liquid.

If side effects occur, reduce the dose or stop taking the drug.

Instructions for use of Furagin (Method and dosage)

For those who have been prescribed Furagin tablets, the instructions for use indicate that they should be taken with meals. This should be done in the following dosages:

• children are given the drug at 5-7 mg/kg per day during standard therapy, as well as 1-2 mg/kg during long-term therapy;
• in case of prevention of infectious and inflammatory diseases, give 1 tablet once in the evening;
• adult patients need to take 2 tablets every day 4 times, at the end of the course they are taken 3 times a day in the same dose.

Instructions for use Furagin recommends simultaneously following a protein diet .

The duration of therapy does not depend on what Furagin is used in each specific case. It should be a maximum of 7-10 days. If necessary, treatment of cystitis with tablets, as well as other inflammatory and infectious diseases of the genitourinary system, can be extended after 10-15 days.

With long-term use, liver and kidney function should be monitored, as well as leukocyte .

Instructions for use Furagin Lect informs that the product is also intended for internal use. Adults should take 50-100 mg, children over 3 years old should take 25-50 mg. The medicine in the prescribed dosage is taken 3 times daily. Therapy is designed for 7-10 days. If the course needs to be repeated, you need to take a break for 10-15 days.

For prevention, take 50 mg of the drug once half an hour before the procedure.

In addition, the drug can be used externally 2-3 times every day to wash wounds or wet bandages. The product is also used as a mouth and throat rinse 2-3 times daily.

Use of the drug Furagin

Furagin is prescribed orally after meals, washed down with plenty of water in a dose of 100–200 mg 2–3 times a day. For children over 5 years of age (body weight 20 kg), the drug is prescribed in a daily dose of 5–7 mg/kg body weight. Depending on the form and course of the disease, the course of treatment is 7–10 days. If necessary and there are no side effects, the course of treatment can be repeated after 10–15 days. For prophylaxis, the drug is prescribed 50 mg (1 tablet) 1 time per day (mainly in the evening).

Overdose

Overdose symptoms:

• dysfunction of the central nervous system: inflammation of peripheral nerves, psychosis , deterioration of mood;
• allergic reactions: angioedema , urticaria , bronchospasm ;
• nausea;
• liver dysfunction.

If the drug is used in excess doses, gastric lavage , as well as drug elimination of overdose symptoms. In severe situations, hemodialysis .

Side effects of the drug Furagin

Possible decrease or loss of appetite, heartburn, nausea, sometimes vomiting, pain in the epigastric region, dizziness, allergic reactions. Sometimes neurotoxic phenomena are observed - headache, dizziness, insomnia, general weakness, increased sweating. In the described cases, the dose of the drug should be reduced or stopped altogether. Side effects are reduced when taking the drug only after meals and when drinking plenty of liquid. With prolonged use of the drug in high doses, as well as in the case of prolonged treatment with low doses, polyneuritis may occur with decreased renal function, cardiac decompensation, or alcoholism. With insufficient liver function, as well as hereditary deficiency of enzymes of the pentose phosphate cycle, acute hemolytic anemia may develop in case of prolonged treatment or use in high doses.

Furagin's analogs

Level 4 ATC code matches:
Furadonin

Furamag

Such analogues of Furagin are known as Furasol and Furamag . These medications cannot be replaced at your own discretion, without consulting your doctor.

Which is better: Furamag or Furagin?

Often on medical forums people ask about Furagin analogues. Most often in this case, Furamag . This product contains potassium furazidin and basic magnesium carbonate .

The differences between Furamag and Furagin mainly lie in the fact that the first drug has higher bioavailability. And in the blood the maximum concentration of its active component remains longer. Accordingly, those who are interested in which is better - Furamag or Furagin - can clearly answer that the bacteriostatic effect of the first remedy is higher.

Furagin for children

Children of all ages often suffer from urinary tract infections However, often an incompletely cured disease can return. This can be avoided if you take the appropriate medications according to the instructions. In this case, experts very often recommend antibiotics . However, if for one reason or another they are not suitable for use, Furagin is prescribed to children. Unlike many antibiotics, it is not addictive.

In addition, this remedy combines well with many other medications. For children who tolerate it well, the drug is prescribed not only for the treatment of inflammatory and infectious diseases , but also for prevention purposes.

However, it should not be given to patients under 1 month of age, especially if the baby is not even a week old. In addition, the drug is prescribed with caution for children under 3 years of age.

The dosage of Furagin for children can be from 5 to 7 mg per 1 kg of weight. For babies up to one year old, the tablets are ground into powder, which is mixed with a certain amount of liquid (milk, formula). If long-term therapy is planned, the specialist reduces the dosage for children to 1-2 mg per 1 kg of weight.

Special instructions for the use of the drug Furagin

It is prescribed with caution in cases of impaired renal function, as well as in patients with diabetes mellitus, since the use of the drug may cause symptoms of polyneuropathy. It is not recommended to prescribe Furagin for urosepsis, as well as for infection of the kidney parenchyma. During the period of use of Furagin, false-positive results of determining glucose in urine using Benedict and Fehling solutions may be observed. It is recommended to determine glucose in urine using the enzymatic method. During long-term treatment with Furagin, the level of blood leukocytes, as well as indicators of liver and kidney function, should be periodically monitored. Furagin does not affect the speed of psychomotor reactions, so it can be prescribed to patients whose activities require increased attention.

Reviews about Furagin

Reviews about Furagin for cystitis and other infectious and inflammatory diseases are very contradictory. The product has helped some, while others complain that they have not noticed any improvement. In addition, you can often find reports that there are side effects when taking pills. However, positive opinions about the drug are still more common.

Parents who gave Furagin to their children also left mostly good reviews. They note the rapid action and effectiveness of this product.

Furagin price, where to buy

Furagin's price is on average about 200 rubles. The medicine is considered to be very affordable compared to analogues; this price of tablets for cystitis makes them a fairly popular remedy. This drug is often prescribed by doctors and is often sought after in pharmacies.

The price of Furagin in Ukraine is also quite affordable. On average it is about 65 hryvnia.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Furagin tablets 50 mg 30 pcs.
  Obolenskoe JSC Obolenskoe farm. enterprise 191 rub. order
• Furagin tablets 50 mg 30 pcs. Olainfarm JSC

  RUB 276 order

• Activetex fom therapeutic coating healing without scars 10x10 n10 (furagin-sea buckthorn oil)Altex Plus

  RUB 308 order

• Furagin tablets 50 mg 30 pcs. Northern StarNorthern Star JSC

  RUB 171 order

• Furagin-Aktifur capsules 50 mg 30 pcs. JSC Obolenskoe farm. company

  RUR 528 order

Pharmacy Dialogue

• Furagin tablets 50 mg No. 30Ozon LLC

  184 RUR order

• Furagin tablets 50 mg No. 30Olainskiy HFZ

  RUB 285 order

• Furagin-LekT 50 mg No. 30 Tyumen.khim. factory

  91 rub. order

• Activtex wipes (FL (furagin, lidocaine) No. 10) Altex LLC

  RUB 229 order

• Furagin (tab. 50 mg No. 30) Usolye-Sibirsky Chemical Physics Complex

  99 RUR order

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Pharmacy24

• Furagin 5 mg N30 tablets PAT "Kievmedpreparat", Ukraine
  47 UAH. order
• Furagin 50 mg No. 30 tablets AT "Olainfarm", Latvia

  79 UAH order

PaniPharmacy

• Furagin tablets Furagin tablets 0.05g No. 30 Latvia, Olainfarm JSC

  90 UAH order

• Furagin tablets Furagin tablets 50 mg No. 30 Ukraine, Kievmedpreparat OJSC

  49 UAH order

• Atraumatic medical napkin with furagin 6x10cm Ukraine, Sarepta-Mediplast

  16 UAH order

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