All about coding for alcoholism with Disulfiram

If you look from the perspective of such a science as biology, then alcoholism is a disease of enzymes. We are talking about those that are responsible for the disposal of alcohol in the body. It is impossible to restore the functioning of these enzymes with medications, so an alcoholic never knows when to stop drinking alcohol. The drugs developed by pharmacological scientists are aimed at causing an aversion to alcohol in an addicted person. They are real assistants to narcologists, as in most cases they successfully return patients to normal life. We will talk about one of them today.

"Disulfiram" is an effective drug for coding against alcoholism

We have already repeatedly told you how to recognize the signs of alcoholism. Today we want to talk about how to get rid of it. Nowadays popular and frequently used

Narcologists use Disulfiram as a drug for the treatment of alcohol dependence. Drugs with the same active ingredient are affordable, they work well both as a stand-alone medicine and in complex therapy. When interacting with alcohol they give a rather violent reaction.

"Disulfiram" has the ability to block the enzyme necessary to neutralize alcohol - aldehyde dehydrogenase. This liver enzyme converts ethanol into carbon dioxide and water. Accumulating in the body, it leads to poisoning. The effect of the drug is based on this feature, after taking which the addicted patient develops symptoms such as nausea, vomiting, headache, dizziness and many other unpleasant sensations. These manifestations are so strong that you can’t even think about drinking.

The principle and feature of the treatment of alcohol addiction with Disulfiram is that the patient must make his own decision and take responsibility for his future life. Treatment is possible only if he understands the danger of combining alcohol with this medicine, otherwise his life may suddenly end due to severe poisoning by the components of the substance.

Action of disulfiram

The use of anti-alcohol medications containing disulfiram is indicated in cases where other treatment methods do not help. They are usually used to combat chronic alcoholism.

When taken, the patient’s body develops a negative conditioned reflex to alcohol. As a result, patients, afraid of experiencing painful sensations, find the strength to refuse to drink alcoholic beverages.

Disulfiram slows down the metabolic processes in the body associated with the processing of ethanol. An intermediate metabolite of ethyl alcohol, acetaldehyde, leads to the process of intoxication. Poisoning is expressed by symptoms:

• vomiting, nausea, diarrhea;
• difficulty breathing, shortness of breath;
• feeling of squeezing in the chest area;
• decreased blood pressure;
• tachycardia;
• redness of the epidermis;
• fever or, conversely, chills;
• inexplicable fear.

Therefore, you can use drugs with disulfiram only a day after your last drink.

To consolidate the body’s negative reaction to alcohol, a medical narcologist performs a teturam alcohol test. To do this, the patient needs to drink a small amount of alcohol. Based on the results of such a test, the dose of the drug can be adjusted if necessary.

Instructions for use of the drug "Disulfiram"

"Disulfiram" is intended for the treatment and prevention of alcohol dependence. It is also used in complex therapy for nickel intoxication. It is produced in the form of tablets, an oil solution for injection, as well as implant capsules.

The drug can be administered either intramuscularly or intravenously. The tablet form of the drug is easy to divide, so the dosage prescribed by the doctor will not be a problem for the patient. It is recommended to take the tablets in the morning.

Implant capsules are injected subcutaneously into the scapula area. They dissolve in the body within two days. The number of implants is determined by the doctor.

"Disulfiram" gel is injected subcutaneously into the scapula area. This procedure is performed exclusively in a hospital and under the supervision of experienced narcologists. However, metheodics are used extremely rarely, as it can provoke a sharp rise in temperature for several days.

"Esperal-gel" is one of the analogues of "Disulfiram". Contact with alcohol leads to severe intoxication.

A gel or capsule containing Esperal for coding against alcoholism is injected under the skin on the shoulder blade, from where it cannot be removed. This introduction of disulfiram, the main component of this gel, ensures its slow release into the blood and a long-lasting effect.

To purchase Disulfiram, a doctor gives a prescription. The dosage of the drug will depend on each specific case. It is prohibited to exceed the dose prescribed by the doctor. Self-medication with the drug is not allowed.

Release forms, composition, analogues

Available in different forms:

• for internal use (oral tablets);
• in the form of injections, gel, tablets or capsules for subcutaneous, intramuscular or intravenous administration.

There are different commercial names for drugs that contain the active ingredient disulfiram, but they have the same effect on the body. The indications, contraindications and possible side effects for these anti-alcohol medications are similar.

Common drugs containing disulfiram that can be purchased in Russia:

• tablet drug Lidevin;
• Antabuse effervescent tablets;
• Esperal gel or tablets;
• Teturam tablets;
• effervescent tablet product Radoter, etc.

They may differ in price and dosage of the active substance. The most common medications are with dosages (mg): 100, 150, 200, 250, 400, 500. In addition to the main active component, medications may contain excipients, so you need to read the instructions before use.

There are two ways to use disulfiram: internally (orally) and subcutaneously. Medicines of the second group are popularly known as “Torpedo coding”.

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Disulfiram and alcohol: consequences that are important to know about

Any pharmaceutical drug has both positive and negative sides.

Disulfiram is no exception. Treatment is contraindicated for them in the following conditions:

• decompensated cardiovascular diseases;
• aggravated damage to the organs of hearing and vision;
• diseases of the gastrointestinal tract during exacerbation;
• malignant neoplasms;
• severe form of tuberculosis;
• diabetes;
• severe kidney pathology;
• pregnancy and lactation;
• drinking alcohol less than 3 days before coding;
• individual intolerance to the components of the drug.

Coding with Disulfiram is prohibited for children under 18 years of age!

Disulfiram is a non-toxic drug, but it can cause side effects such as spatial disorientation, unpleasant taste in the mouth, headaches, anaphylaxis, and neurological disorders. In addition, sometimes the body odor of the addict changes during the drug encoding.

Disulfiram-like reactions when taking alcohol

If the patient ignored the doctor’s warning and still took alcohol while being coded with Disulfiram, he should be immediately hospitalized. Sometimes it is enough to take 50 grams of alcohol for the consequences to become irreversible. In case of severe intoxication of the body, doctors urgently carry out removal (decoding) of implants and detoxification therapy.

The consequences of incontinence can manifest themselves in the form of:

• headaches;
• nausea and vomiting;
• tachycardia or bradycardia;
• shortness of breath;
• disorientation;
• seizures;
• collapse followed by a heart attack.

Contraindications

The drug is prescribed only after a thorough medical examination. Disulfiram is usually prescribed to those who have not been helped by simpler and safer treatments. If the patient drank alcohol 48 hours before the appointment, then the first dose is postponed to a later date. The substance is strictly contraindicated for those with mental disorders. Problems always occur in those who suffer from liver and respiratory failure. The drug is not prescribed to those who have heart, vascular, or gastrointestinal diseases. It’s bad if the patient has a stomach ulcer or erosion. The use of Disulfiram is dangerous for pregnant and lactating women. The instructions prohibit administering the substance to adolescents; it is highly undesirable to treat elderly people with it.

It is important to know: treating alcoholism is a complex process. Much of the success will depend on the patient himself, his desire and desire to be cured. Introducing Disulfiram against your will can end in disaster. Before starting treatment, it is advisable to undergo a course of therapy with a psychiatrist. Ignoring this point can lead to serious illnesses and mental disorders. Narcologists speak positively about this drug. Many patients were able to overcome alcoholism and become normal people.

"Disulfiram" intravenously: how much is in the body?

The dosage of a medicine directly affects its duration of action. It can only be determined by a narcologist!

Intravenous administration of the drug gives positive dynamics for one year. The substance works actively for 2-3 months, and then the coding is based on the psychological component of the coding.

The tablets are effective for no more than two days, the “Disulfiram” injection given intramuscularly is active for 8-9 months. As an implant, Disulfiram will work for 5-8 months.

After discontinuation of the drug or after forced decoding, the effect of the medicine will continue for another week to two.

How to find out if there is disulfiram in the body

Finding out whether this substance is still present in the tissues and blood is quite simple: you need to drink a little alcohol. And you will receive a response from the body in the form of “chemical protection”: shortness of breath, tachycardia, sweating, vomiting with nausea.

We advise you to immediately call an ambulance, since the consequences of such a step are unpredictable - heart attack, cerebral edema, coma, death. It seems that there are not many daredevils to play “Russian roulette” with the body.

Directions for use and dosage

The daily dose of Disulfiram for oral administration is 125-500 mg.

Intramuscular or subcutaneous implantation is performed in the left iliac region. Before the procedure, disinfection of the injection site and local anesthesia are necessary. After this, a 6 mm incision is made. 2 implantation tablets should be inserted using a trocar parallel to the skin surface. The remaining 6 tablets are introduced later, 2 pieces at a time, so that all 8 are located crosswise relative to the incision. Then stitches and a sterile dressing are applied. The procedure can be repeated after 8 months.

How to remove the drug "Disulfiram" from the body?

Sometimes an addicted person is faced with situations that require immediate removal of the drug from the body. Only narcologists are proficient in these techniques. It is impossible to neutralize the effect of Disulfiram on your own!

It is also important to remember that there is no antidote for Disulfiram - this is a feature of the medicine. Removal of chemical protection against alcohol can only be carried out by a doctor in a hospital setting. The only option is to remove the implant. Treatment for alcoholism will be nullified. Subsequent encodings will no longer bring the expected result.

However, ascorbic acid, Piracetam, diuretics such as Lasix, and H1 blocking drugs such as Ephedrine can serve as antidotes for Disulfiram.

Antidote

Often, drugs that contain disulfiram are forcibly administered to a person, against his will. Almost always such a patient tries to find an antidote. But it doesn’t exist, and it won’t be possible to remove the substance ahead of time. If a strong reaction to alcoholic beverages occurs, doctors begin gradual intoxication. This is a rather long, complex process. You will need to administer ascorbic acid, Ephedrine, and H1 blockers. This can take from twelve hours to two days. But Disulfiram will not be completely removed - the degree of human poisoning will simply decrease.

Such procedures are carried out only in emergency cases; the removal itself can have a negative impact on the body. A serious dose of ascorbic acid often leads to irreversible consequences and physiological damage. This can cause stomach ulcers or cirrhosis of the liver. There are known cases of impotence and cancer. Many narcologists recommend being extremely careful when using the drug. You can always consult a psychiatrist or undergo a simpler course of therapeutic treatment.

Find out the price of Disulfiram for alcoholism coding

The cost of disulfiram coding is strictly individual and depends on the period for which the coding will be performed and with what drug.

The total cost will depend on the volume of medical care provided in the clinic or at home, treatment of concomitant diseases, the patient’s stay in hospital before coding and other factors. Almost every drug treatment center develops treatment programs designed for patients with different income levels.

Coding with Disulfiram in Moscow costs approximately 24–25 thousand rubles. You can get more information by contacting the clinic directly through communication channels convenient for you.

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Read reviews about disulfiram coding for alcoholism

“Our father is an alcoholic with a long history. No matter what they did, no matter how they influenced him both in the family and at work, there was zero reaction on his part. After coming out of yet another binge, during which he almost said goodbye to his life, he promised to encode us. The narcologist recommended the drug “Disulfiram”. We explained to my father all the positive and negative aspects of coding, and he signed an agreement to voluntarily give up alcohol. 7 months have passed since the date of encoding. They were difficult, but the father kept his word. Now she plans to have it stitched again to consolidate the results of the treatment. The most important thing is that during these 7 months he completely revised his views on life. We hope this is forever."

Frolov family, Astrakhan

Approaches to coding for alcoholism with Disulfiram abroad

Narcologists from different countries believe that the patient’s decision to quit alcohol addiction using the coding method must be conscious, otherwise it will not be effective. The addict must tell his decision not only to the doctor, but also to his family members.

Such interaction between the doctor and the patient’s family members will provide him with real psychological support. Together they will make the best decision regarding the type of coding for alcoholism.

Drug treatment centers abroad have been using the Disulfiram coding method for more than 20 years. The method has been tested and effectively helps develop the alcohol aversion reflex. Thanks to him, a large number of alcohol addicts were able to return to normal life.

Indications for use

The indication for the use of disulfiram is alcohol dependence in various forms and at different stages. Before the coding procedure, the narcologist explains to the patient in detail the principle of action of the substance and talks about the possible consequences. Only after the patient has signed consent to the coding procedure does the doctor begin the procedure itself. In no case should you secretly give disulfiram to an addict - alcohol, once in the body, will cause severe poisoning, and after such cases it is not always possible to save the person. Also, coding is not carried out against the will of the addict - this is determined by the legislation of the Russian Federation.

Features of Disulfiram coding in Israel at the Renaissance Clinic

Renaissance is the best drug treatment clinic in Israel. She rightfully occupies a leading position in the treatment and rehabilitation of patients with alcohol addiction. The center values ​​its reputation; coding techniques here are constantly being improved at all stages. This also applies to disulfiram coding.

In rehabilitation, patients can be treated for alcoholism on an outpatient or inpatient basis for 1-12 months. The clinic is licensed by the Israeli Ministry of Health. All addicts are guaranteed to receive qualified medical care.

The center's doctors will provide you with information about everything you need to know about alcoholism treatment in Israel. You will also be pleasantly surprised by the fairly loyal pricing policy for alcohol addiction treatment. It is unnecessary to remind you that all treatment services in Israel will be provided to you anonymously.

Let us emphasize once again: only a narcologist can give injections for alcohol dependence, choose drugs, the method of administration and dosage, taking into account the patient’s health condition, the stage and type of his alcohol dependence. Self-medication or dubious “specialists” can take away from you at least your money, and at most your life!