Diarrhea is an extremely unpleasant disorder that can take both children and adults by surprise. Stopdiar will help eliminate the cause of the disease - harmful bacteria. The drug is distinguished by a variety of dosage forms, the absence of a negative effect on the intestinal microflora and an affordable price.
Medicine Stopdiar - composition
Film-coated tablets. One tablet contains:
- active ingredient nifuroxazide 100 mg;
- excipients: talc , colloidal silicon dioxide , potato starch , gelatin , magnesium stearate ;
- film shell composition: talc , hypromellose , titanium dioxide , polyethylene glycol 20000 , quinoline yellow dye .
Suspension for oral administration, 5 ml of suspension contains:
- active ingredient nifuroxazide 220 mg;
- excipients: carbomer , sucrose , sodium hydroxide , citric acid monohydrate , 30% simethicone antifoam emulsion , methyl parahydroxybenzoate , banana flavor .
Review of dosage forms
So that every buyer can choose the right option, Stopdiar is available in three dosage forms:
- round yellow film-coated tablets, one piece contains 100 mg of nifuroxazide, each package contains 24 tablets in an aluminum blister and instructions for use;
- yellow gelatin capsules containing 200 mg of nifuroxazide, one package contains 12 pieces;
- suspension, 5 ml of which contains 220 ml of nifuroxazide. It has a light yellow color and a banana smell. The 125 ml dark glass bottle is sold complete with a measuring spoon.
The main component of all forms is a substance with an antibacterial effect, nifuroxazide. Excipients in tablets include talc, colloidal silicon dioxide, potato starch, gelatin, magnesium stearate.
The suspension contains sucrose, sodium hydroxide, citric acid monohydrate, simethicone, methyl parahydroxybenzoate, banana flavor. The capsules additionally contain corn starch, magnesium stearate, sucrose, and pregelatinized corn starch.
Pharmacodynamics and pharmacokinetics
The active ingredient Stopdiar nifuroxazide belongs to the group of nitrofurans and, when taken orally, has an antibacterial effect on pathogenic and opportunistic microorganisms that cause intestinal infections. Nifuroxazide is active against gram-positive ( staphylococci, streptococci ) and gram-negative ( salmonella , shigella , klebsiella , Escherichia coli ) bacteria, which are most often the causative agents of intestinal infections.
The action of Stopdiar is associated with the suppression of the action of enzymes involved in the cellular metabolism of infectious agents. Due to metabolic disorders, bacterial cell membranes are destroyed and the cells die.
The activity of Stopdiar against infectious agents does not decrease even with a long course of treatment. At the same time, it does not destroy the beneficial intestinal microflora, therefore, after its use, it takes less time to restore the digestive process than when using antibiotics. The effect of the drug does not depend on the acidity in the intestines.
After ingestion of capsules or suspensions, the active substance is practically not absorbed in the intestines, does not enter the blood and does not have a systemic effect on the body. It acts directly in the intestines and is then excreted from the body naturally through feces.
Mechanism of action of the drug
Due to nifuroxazide, Stopdiar has an antibacterial effect against pathogens of intestinal infections - pathogenic or opportunistic microorganisms.
The medication inhibits the action of enzymes involved in the metabolism of infectious agents at the cell level. As a result of the destruction of cell membranes, bacteria die.
Stopdiar is active against infectious agents during long courses of treatment and does not have a negative effect on the intestinal microflora. The substance is not an antibiotic, so restoration of the gastrointestinal tract after treatment does not take much time.
The main component does not enter the bloodstream, is minimally absorbed in the intestines, and has no systemic effect on the body. The drug gives a therapeutic effect in the intestines and is eliminated from the body naturally.
Contraindications for the use of Stopdiar
Contraindications for the use of tablets:
- allergies to drugs from the group of 5-nitrofuran derivatives ;
- increased sensitivity of the body to other components of the drug;
- age up to seven years.
Contraindications for use of the suspension:
- allergies to drugs from the group of 5-nitrofuran derivatives ;
- increased sensitivity of the body to other components of the drug;
- age up to two months;
- prematurity.
It is recommended to take the medicine with caution during pregnancy and breastfeeding , since clinical trials have not been conducted on these categories of patients.
Contraindications and side effects
The instructions for use of Stopdiar indicate that the drug is not prescribed for hypersensitivity to nifuroxazide or other ingredients of the dosage forms.
The conditions under which Stopdiar is prohibited depend on its type. Tablets are not prescribed to preschool children, the suspension is not prescribed to premature infants and newborns under two months of age.
Capsules are contraindicated for persons with fructose intolerance, glucose-galactose malabsorption syndrome, children under three years of age, and pregnant women.
As a rule, the medication does not cause adverse reactions and is easily tolerated by patients. However, if there is a personal hypersensitivity to this antibacterial substance, then the following may occur:
- pain in the abdomen;
- attacks of nausea and loose stools;
- skin rash;
- allergic reactions in the form of shortness of breath, swelling of the tongue, face and lips, skin rashes and itching.
Side effects of Stopdiar
The drug is usually well tolerated by all patients and only in isolated cases does its side effects appear:
- from the stomach and intestines - transient abdominal pain, nausea may appear, and symptoms of diarrhea will intensify; this does not require interruption of the course of treatment;
- allergic reactions - urticaria , Quincke's edema , breathing problems. In such circumstances, you should stop taking the drug immediately.
special instructions
When treating with Stopdiar, it is important to drink enough fluid to replenish fluid loss due to diarrhea.
Avoid drinking alcoholic beverages due to the risk of a disulfiram-like reaction. If you have an allergic reaction, you should stop taking the medication and consult a doctor.
The ability to drive a car or operate complex machinery is not affected.
If the patient takes several medications, then it is necessary to wait 2-3 hours between doses, since Stopdiar is able to remove another drug from the body and prevent it from being absorbed.
Instructions for use of Stopdiar (Method and dosage)
Instructions for Stopdiar : swallow the tablets without chewing and wash them down with water every 6 hours. Taking Stopdiar does not depend on diet. Adults and children over six years of age should take 200 mg (2 tablets) 4 times a day for a week.
Instructions for Stopdiar - suspension for children : the suspension is given to the child every 6 - 8 hours, without connecting it with feeding; Before use, the bottle is thoroughly shaken to ensure uniformity of the suspension, after which the suspension is dosed using a measuring spoon (1 small measuring spoon per 2.5 ml contains 110 mg of the drug, 1 large measuring spoon per 5 ml - 220 mg). Instructions for children recommend the following age-specific dosages of the drug:
- 1 – 6 months: 110 – 220 mg (1-2 scoops per 2.5 ml) twice a day;
- 6 months - 6 years: 220 mg (1 scoop per 5 ml) three times a day;
- 6 - 18 years and adults: 220 mg (1 scoop per 5 ml) four times a day.
The duration of use of Stopdiar suspension for children should not exceed one week. Treatment should be carried out under the supervision of a physician, since intestinal infection , especially in young children, often leads to dehydration and associated severe complications. Therefore, it is necessary to constantly replenish fluid loss.
How to take Stopdiar
The method and regimen of use depend on the dosage form of the drug.
In accordance with the instructions for use of Stopdiar, tablets are taken 4 times a day with an interval of 6 hours.
Adults and children over the age of seven are prescribed two pieces. The tablets cannot be crushed, they cannot be chewed, but must be swallowed whole and washed down with a sufficient amount of water. The duration of therapy is three days. If symptoms persist, you should see a doctor.
Capsules are prescribed for adults and children over 6 years old, one capsule four times a day, for children 3-6 years old, one capsule three times a day. The course of treatment is three days.
The suspension is taken in accordance with the dosages recommended by the manufacturer:
- adults and children over 6 years old – 5 ml four times a day;
- children from 6 months to 6 years – 5 ml three times a day;
- infants from 2 to 6 months – 2.5-5 ml twice a day.
Before use, the contents of the bottle must be shaken so that the substance becomes homogeneous. Duration of treatment: 5-7 days.
Analogues of Stopdiar
Level 4 ATC code matches:
Levorin
Sangviritrin
Ersefuril
Nifuroxazide
Analogs are drugs from different medicinal groups that are used to treat the same diseases. An analogue of Stopdiar is Furazolidone , a drug from the nitrofuran group, but with a different active ingredient. Furazolidone is one of the first drugs from the group of nitrofuran derivatives, which was prescribed for the treatment of intestinal infections. Its effectiveness is certainly lower than that of Stopdiar.
Synonyms for the drug are Enterofuril, Ersefuril, Diastat, Nifuroxazide . In all these drugs, the active ingredient is nifuroxazide.
Stopdiar price, where to buy
The price of one package of Stopdiar tablets in Moscow ranges from 128 to 158 rubles; Stopdiar suspensions price from 214 to 247 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Stopdiar capsules 200 mg 12 pcs. Gedeon Richter Poland LLC
258 rub. order - Stopdiar susp. for internal approx. 220mg/5ml 90mlGedeon Richter Romania JSC/JSC Gedeon Richter
RUB 377 order
- Stopdiar tablets p.p.o. 100 mg 24 pcs. Gedeon Richter Poland LLC
RUB 195 order
Pharmacy Dialogue
- Stopdiar (tablet p/o 100 mg No. 24) Gedeon-Richter
RUB 218 order
- Stopdiar (susp. for intravenous administration 220 mg/5 ml 90 ml) Gedeon-Richter
RUB 356 order
- Stopdiar (caps. 200 mg No. 12) Gedeon-Richter
RUB 292 order
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Pharmacy24
- Stopdiar 200 mg No. 12 capsules TOV "Gedeon Richter Poland", Poland
93 UAH.order
PaniPharmacy
- Stopdiar capsule Stopdiar capsule. 200 mg No. 12 Poland, Gedeon Richter Poland
89 UAH order
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