Nazol nasal spray 0.025 mg/dose 150 doses 10 ml bottle 1 pc. in Moscow
benzalkonium chloride (50% solution), benzyl alcohol, disodium edetate, macrogol 400, povidone, propylene glycol, sodium hydrogen phosphate, sodium dihydrogen phosphate, purified water up to 100 ml. Description. Transparent, colorless, odorless solution.
Pharmacotherapeutic group: anticongestive agent - vasoconstrictor (alpha2-adrenergic agonist).
ATX code: R01AA05
pharmachologic effect
Oxymetallip belongs to the group of alpha-agonists for topical use. Has a vasoconstrictor effect. When administered intranasally, it reduces swelling of the mucous membrane of the upper respiratory tract, which leads to easier nasal breathing and the opening of the mouths of the paranasal sinuses and eustachian tubes. The effect of the drug appears 10-15 minutes after use and lasts for 10-12 hours.
Indications for use
To facilitate nasal breathing during colds and viral infections of the upper respiratory tract, sinusitis, rhinitis of any etiology.
Contraindications
- hypersensitivity to the drug or its components; atrophic rhinitis: children under 6 years of age
pregnancy - lactation period
The drug should be used with caution in patients suffering from diseases of the cardiovascular system (arterial hypertension, coronary heart disease, chronic heart failure, tachycardia, arrhythmias), impaired carbohydrate metabolism (diabetes mellitus), thyroid function (hyperthyroidism), pheochromocytoma, chronic renal insufficiency, prostatic hyperplasia (urinary retention) and closed-angle glaucoma, taking monoamine oxidase inhibitors, tricyclic antidepressants.
Directions for use and doses
Intranasally. Adults and children over 12 years old - 2-3 injections into each nasal passage 2 times a day.
Children from 6 to 12 years old - 1 injection into each nasal passage 2 times a day. The drug should not be used more than 2 times a day. Duration of treatment:
It is not recommended to use the drug for more than 3 days. With frequent or prolonged use of the drug, the feeling of difficulty in nasal breathing may reappear or worsen. If these symptoms appear, you should stop treatment and consult a doctor. When spraying, do not tilt your head back and do not spray while lying down.
Side effect
Sometimes burning or dryness of the nasal membranes, dry mouth and throat, sneezing, increased volume of secretions released from the nose. In rare cases, after the effect of the drug wears off, a strong feeling of “stuffiness” in the nose (reactive hyperemia).
Side effects caused by the systemic action of the drug: increased blood pressure, headache, dizziness, palpitations, increased anxiety, nausea, insomnia. With long-term use of the drug (more than 7 days), the following are possible: reactive hyperemia of the nasal mucosa, atrophy of the nasal mucosa, tachyphylaxis (rapid decrease in the therapeutic effect with repeated use).
Overdose
Long-term or frequent use of the drug in the nasal cavity can cause nausea, increased blood pressure, tachycardia, and central nervous system depression. Treatment is symptomatic.
Interaction with other drugs
When used simultaneously with MAO inhibitors (including the period within 14 days after their withdrawal) and tricyclic antidepressants, an increase in blood pressure may be observed. The drug slows down the absorption of local anesthetic drugs and prolongs their effect. Co-administration of other vasoconstrictor drugs increases the risk of side effects.
special instructions
Use during pregnancy and breastfeeding is only possible if the intended benefit to the mother is superior! possible risk to the fetus or infant.
Use the recommended dosage without consulting a doctor for more than 3 days. Avoid getting the drug into your eyes.
To avoid the spread of infection, it is necessary to use the drug individually.
Nazol nasal spray 0.025% 10ml
Compound
1 ml: - oxymetazoline hydrochloride 500 mcg Excipients: benzalkonium chloride (50% solution), benzyl alcohol, disodium edetate, macrogol 400, povidone, propylene glycol, sodium hydrogen phosphate, sodium dihydrogen phosphate, purified water.
Pharmacokinetics
Pharmaceutical group: anticongestive agent - vasoconstrictor (alpha-adrenergic agonist). Pharmaceutical action: Nazol is an alpha-adrenergic stimulating agent for topical use. Oxymetazoline belongs to the group of alpha-agonists for topical use. Has a vasoconstrictor effect. When administered intranasally, it reduces swelling of the mucous membrane of the upper respiratory tract, which leads to easier nasal breathing and the opening of the mouths of the paranasal sinuses and eustachian tubes. The effect of the drug appears 10-15 minutes after application and continues for 10-12 hours.
Contraindications
hypersensitivity to the drug Nazol or its components, atrophic rhinitis, children under 6 years of age, pregnancy, lactation. The drug Nazol should be used with caution in patients suffering from diseases of the cardiovascular system (arterial hypertension, coronary artery disease, chronic heart failure, tachycardia, arrhythmias), impaired carbohydrate metabolism (diabetes mellitus), thyroid function (hyperthyroidism), pheochromocytoma, chronic renal failure , prostatic hyperplasia (urinary retention) and angle-closure glaucoma, taking MAO inhibitors, tricyclic antidepressants.
Directions for use and doses
Intranasally. Adults and children over 12 years old - 2-3 injections of Nazol into each nasal passage 2 times a day. Children from 6 to 12 years old - 1 injection into each nasal passage 2 times a day. You should not use Nazol more than 2 times a day. Duration of treatment: it is not recommended to use the drug for more than 3 days. With frequent or prolonged use of the drug, the feeling of difficulty in nasal breathing may reappear or worsen. If these symptoms appear, you should stop treatment and consult a doctor. When spraying, do not tilt your head back and do not spray while lying down.
Storage conditions
In a place protected from light, at a temperature not exceeding 25C.
Best before date
3 years.
special instructions
Use the recommended dosage without consulting a doctor for more than 3 days. Avoid getting the drug into your eyes. To avoid the spread of infection, it is necessary to use the drug individually.
Conditions for dispensing from pharmacies
Available without a prescription
Side effects
Sometimes burning or dryness of the nasal membranes, dry mouth and throat, sneezing, increased volume of secretions released from the nose. In rare cases, after the effect of the drug wears off, a strong feeling of nasal congestion (reactive hyperemia) occurs. Side effects caused by the systemic action of the drug: increased blood pressure, headache, dizziness, palpitations, increased anxiety, nausea, insomnia. With long-term use of the drug Nazol (more than 7 days), the following are possible: reactive hyperemia of the nasal mucosa, atrophy of the nasal mucosa, tachyphylaxis (rapid decrease in the therapeutic effect with repeated use).
Interaction
When Nazol is used simultaneously with MAO inhibitors (including a period of 14 days after their discontinuation) and tricyclic antidepressants, an increase in blood pressure may be observed. The drug slows down the absorption of local anesthetic drugs and prolongs their effect. Co-administration of other vasoconstrictor drugs increases the risk of side effects.
Overdose
Long-term or frequent use of the drug Nazol in the nasal cavity can cause nausea, increased blood pressure, tachycardia, and central nervous system depression. Treatment is symptomatic.
Nazol nasal spray 0.5 mg/ml 30 ml No. 1
Description
Transparent, colorless, odorless liquid.
Main active ingredient
Oxymetazoline
Release form
Nasal spray
Dosage
0.05% 30 ml
Special instructions and precautions
With longer use and overdose of topical decogents, their effect may weaken. As a consequence of their abuse, the following may occur: reactive hyperemia of the nasal mucosa (rebound effect), chronic swelling of the nasal mucosa (rhinitis medicamentosa), atrophy of the mucous membrane. The benzalkonium chloride (preservative) contained in the composition can cause swelling of the nasal mucosa when used for a long time. If you suspect the above, stop using the drug or replace it with a drug without a preservative.
Pharmacological properties
Oxymetazoline hydrochloride causes vasoconstriction of the mucous membranes of the nose, paranasal sinuses and eustachian tube, which causes a mild and lasting reduction in their swelling and leads to easier nasal breathing. Relief in nasal breathing occurs 5-10 minutes after injection into the nasal cavity and lasts about 12 hours. The glycols contained in the preparation have a softening effect on the irritated mucous membrane of the nasal sinuses and protect it from excessive drying. As a result, the nasal mucosa retains the ability to naturally warm, moisturize and cleanse the inhaled air.
Indications for use
Difficulty in nasal breathing due to colds, flu, ARVI, allergic rhinitis, sinusitis.
Directions for use and doses
Inject one by one into each nasal passage; do not throw your head back when injecting. Adults and children over 12 years of age: 2-3 sprays into each nasal passage. Children 6-12 years old: 1 injection. Repeat injections no earlier than after 12 hours. Do not exceed the recommended dosage and do not use the drug for more than 7 days.
Use during pregnancy and lactation
When used during pregnancy or breastfeeding, do not exceed the recommended dosage. Use is possible only after a thorough assessment of the risk-benefit ratio for the mother and fetus.
Impact on the ability to drive a car and operate machinery
Does not affect. After long-term use in dosages exceeding the recommended ones, a general effect on the cardiovascular system and the central nervous system cannot be excluded. In these cases, the ability to operate a vehicle or operate machinery may be reduced.
Interaction with other drugs
Taking tricyclic antidepressants or MAO inhibitors at the same time or immediately before using oxymetazoline may lead to an increase in blood pressure.
Contraindications
Increased individual sensitivity to the ingredients of the drug; atrophic rhinitis; arterial hypertension; severe atherosclerosis; tachycardia; increased intraocular pressure, angle-closure glaucoma; hyperthyroidism; diabetes; pheochromocytoma; severe renal dysfunction; difficulty urinating due to prostate enlargement; after transsphenoidal hypophysectomy or after other surgical intervention that affects the dura mater; simultaneous use of MAO inhibitors; children under 6 years of age.
Compound
Active ingredient: oxymetazoline hydrochloride 0.5 mg/ml. Excipients: benzalkonium chloride, disodium edetate dihydrate, macrogol 400, povidone, propylene glycol, disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate, purified water.
Overdose
After a significant overdose or accidental ingestion, symptoms associated with both hyperactive phases and inhibitory phases of the central nervous system may occur. Stimulation of the central nervous system manifests itself in anxiety, agitation, hallucinations and seizures. CNS depression manifests itself in a decrease in body temperature, lethargy, drowsiness, and coma. Additional symptoms may be observed: miosis, mydriasis, nausea, vomiting, cyanosis, fever, sweating, pallor, spasms, palpitation, tachycardia, bradycardia, arrhythmia, cardiovascular failure, cardiac arrest, arterial hypertension, respiratory depression, apnea, pulmonary edema . Treatment: taking activated carbon, sodium sulfate (laxative), gastric lavage. Vasopressors should not be taken. If necessary, reduce the temperature, anticonvulsant therapy.
Side effect
Common: burning or dryness of the nasal membranes, sneezing. Uncommon: after the effect of using the drug wears off, a strong feeling of nasal congestion (reactive hyperemia), nosebleeds, allergic reactions (Quincke's edema, urticaria, itching). Rarely: palpitations, tachycardia, arterial hypertension. Very rare: apnea in infants, insomnia, fatigue (drowsiness, sedation), headache, restlessness, hallucinations (mainly in children), arrhythmia, convulsions (especially in children).
Storage conditions
At a temperature not exceeding 30 °C, out of the reach of children.
Buy Nazol spray nas. 0.5 mg/ml in bottle with nas.-sp. 30 ml in pack No. 1 in the pharmacy
Price for Nazol spray nas. 0.5 mg/ml in bottle with nas.-sp. 30 ml in pack No. 1
Instructions for use for Nazol spray naz. 0.5 mg/ml in bottle with liquid dispenser 30 ml in pack No. 1
