Combilipen: features of the use of vitamins

Compound

The composition of 1 ml of Combilipen solution includes the following active ingredients: thiamine hydrochloride - 50 mg, pyridoxine hydrochloride - 50 mg, cyanocobalamin - 500 mcg, lidocaine hydrochloride - 10 mg.
As excipients: benzyl alcohol, sodium hydroxide, potassium hexacyanoferrate, sodium tripolyphosphate, water for injection. The composition of 1 tablet of the drug includes: pyridoxine hydrochloride - 100 mg, benfotiamine - 100 mg, cyanocobalamin - 2 mcg. As excipients: carmellose sodium, microcrystalline cellulose, povidone K30, calcium stearate, talc, polysorbate, sucrose.

pharmachologic effect

The drug is a multivitamin complex, which includes several components.

Thiamine hydrochloride (vitamin B1) provides glucose to the body's nerve cells. Lack of glucose leads to deformation and subsequent enlargement of nerve cells, which ultimately provokes a violation of their immediate functions.

Pyridoxine hydrochloride (vitamin B6) is directly involved in the metabolic processes of the central nervous system. It ensures the normalization of the conduction of nerve impulses, excitation and inhibition, and also takes part in the synthesis of catecholamines ( adrenaline , norepinephrine ) and in the transport of sphingosine (a component of the nerve sheath).

Cyanocobalamin (vitamin B12) is involved in the production of choline, the main substrate for the synthesis of acetylcholine (acetylcholine is a neurotransmitter that takes part in the conduction of nerve impulses), hematopoiesis (promotes the maturation of red blood cells and ensures their resistance to hemolysis). Cyanocobalamin is also involved in the synthesis of nucleic acids , folic acid , and myelin . It increases the ability of body tissues to regenerate.

special instructions

During the therapeutic course, you should not simultaneously take other multivitamin complexes that contain B vitamins.

If injections or tablets are taken together with Levodopa, the effect of vitamin B6 on the human body is significantly reduced.

Before starting treatment, you need to consult a specialist. If treatment is carried out with Combilipen, then it is best to refrain from driving a vehicle and other dangerous mechanisms for the first time after taking it.

Indications for use of Kombilipen

Indications for the use of this drug are a number of neurological diseases:

• trigeminal neuralgia;
• inflammation of the facial nerve;
• polyneuropathy , which has different origins: diabetic and alcoholic;
• pain in patients suffering from spinal diseases: intercostal neuralgia , lumbar and cervical syndrome , cervicobrachial syndrome , radicular syndrome , pathological changes in the spine.

The price and reviews of the drug’s effect on the treatment of these diseases indicate its high effectiveness when used in complex therapy.

Instructions for use of Kombilipen (Method and dosage)

When using a solution of the drug, injections are given intramuscularly.

If the symptoms of the disease are pronounced, injections are carried out for 5-7 days, 2 ml daily, after which the administration of Combilipen continues 2-3 times a week for another two weeks.

For mild forms of the disease, injections are carried out 2-3 times a week for no more than 10 days. Treatment with Kombilipen solution is carried out for no more than two weeks, the dosage is adjusted by the attending physician.

Instructions for use of Combilipen Tabs tablets

The drug should be taken after meals, washed down with a small amount of water, and not chewed. Adult patients take 1-3 tablets daily. The course of treatment is prescribed by a specialist. High doses of the drug should not be taken for longer than four weeks.

Interaction

If Kombilipen injections or oral administration of the drug are combined with treatment with Levodopa, the effect of vitamin B6 .

You cannot inject medications with substances that have a redox effect, as they are incompatible with vitamin B1 . These are mercuric chloride , carbonate , iodide , acetate , tannic acid .

In addition, thiamine intake cannot be combined with sodium phenobarbital , riboflavin , metabisulfite , benzylpenylene , dextrose .

Thiamine is destroyed very quickly when in contact with copper. Thiamine inactivation also occurs when the pH exceeds 3.

Vitamin B12 is not compatible with heavy metal compounds.

Overdose

If the therapeutic dosage of the drug is exceeded, symptoms of overdose may occur. These include:

• nausea;
• vomit;
• hives;
• Quincke's edema;
• dizziness;
• convulsions;
• disturbance of consciousness;
• heart rhythm disturbance.

If any of the above symptoms occur, it is recommended to stop taking the drug and consult a doctor. In the presence of severe overdose, hospitalization is indicated. There is no specific antidote. To alleviate the condition, symptomatic therapy is used.

Analogs

Level 4 ATX code matches:
Neurobex Forte

Neurobex

Milgamma Compositum

Milgamma

Neurorubin

Neurobion

Pharmacies sell analogues of Kombilipen, which contain similar active ingredients. There are a large number of multivitamin preparations that contain vitamins. The price of analogues varies widely. When choosing an analogue, you should take into account what Combilipen is and what vitamins are included in its composition.

Which is better: Milgamma or Combilipen?

The drugs Milgamma and Kombilipen are analogs and are manufactured by different manufacturers. Both drugs have a similar effect on the human body. However, the cost in Milgamma pharmacies is higher.

Kombilipen's analogs

Taking Combilipen may be contraindicated or impossible for a number of other reasons. In such cases, doctors advise using analogues of the drug. The main ones include:

• Milgamma;
• Neuromultivitis;
• Neurobion;
• Pentovit;
• Compligam;
• Neurobion;
• Movalis;
• Mydocalm;
• Cocarnit;
• Vitaxon.

Which is better: Combilipen or Milgamma?

Milgamma is a complex drug whose active substances are B vitamins. The drug has an analgesic, metabolic and neuroprotective effect. Available in the form of tablets and solution for intramuscular administration. Used for medicinal and prophylactic purposes. The main indications for prescribing Milgamma include:

• neuritis;
• neuralgia;
• neuropathy of various origins;
• convulsive syndrome;
• complex therapy of degenerative-dystrophic diseases of the spine.

The drug is not used in the presence of individual intolerance to its components, heart failure in the stage of decompensation, during pregnancy and lactation, as well as in childhood.

Combilipen and Milgamma belong to the same pharmacological group. Used to treat various neurological conditions. Medicines have similar active substances, release forms, and contraindications for use. The differences between the drugs are as follows:

• Milgamma is produced by a German pharmaceutical company. Combilipen is a domestically produced drug;
• Milgamma contains a larger number of excipients that increase the absorption of vitamins;
• Milgamma is less likely to cause side effects compared to Combilipen.

Before purchasing medications from a pharmacy, it is recommended to consult a doctor. The specialist will be able to select the required dosage, frequency of administration and duration of treatment.

Which is better: Combilipen or Neuromultivit?

Neuromultivitis is a complex medicine. The active components of the drug are pyridoxine, thiamine, cyanocobalamin. It is produced in the form of tablets and solution for intramuscular administration. Neuromultivitis has neurometabolic and analgesic effects. Indications for prescribing the drug are:

• diabetic and alcoholic polyneuropathy;
• neuralgia of various origins;
• radicular syndrome;
• neuritis;
• lumboischialgia.

Neuromultivit is not prescribed in case of individual intolerance to the components of the drug, during pregnancy and breastfeeding, or in the presence of heart failure.

Combilipen and Neuromultivit are representatives of the same pharmacological group. The drugs are prescribed for the presence of various neurological diseases. Available in the form of tablets and solution for intramuscular administration. A similar composition provides the same indications, side effects and contraindications.

The excipient of Combilipen is lidocaine. It allows you to reduce pain during injection of the drug. Neuromultivit does not contain this component. Neuromultivit is produced by a European pharmaceutical company. Combilipen is a domestically produced medicine.

Which is better: Combilipen or Neurobion?

Neurobion is one of the complex preparations that contain B vitamins. It is available in the form of tablets and solution for injection. The drug helps to replenish vitamin deficiency and has an analgesic and neurometabolic effect. Among the main indications for prescribing the drug are:

• neuralgia;
• neuritis;
• pain syndrome caused by degenerative-dystrophic diseases of the musculoskeletal system.

Neurobion is not used during pregnancy and lactation. This is due to the high levels of vitamins. In addition, the drug is contraindicated in case of individual intolerance to its components, under the age of 18 years.

Combilipen and Neurobion are combined vitamin complexes. The drugs are similar in composition, indications for use, release form and side effects. Neurobion is produced by a European pharmaceutical company, Combilipen is a domestic drug.

Which is better: Combilipen or Pentovit?

Pentovit is a multivitamin complex medicine. The active ingredients of the drug are pyridoxine, thiamine, folic acid, cyanocobalamin and nicotinamide. Produced in tablet form. Among the main indications for prescribing Pentovit are:

• dermatitis;
• neuralgia of various origins;
• hypovitaminosis;
• asthenia;
• rehabilitation period after infectious diseases.

The dosage, frequency of administration and duration of treatment are selected by the doctor individually. Pentovit is not used in pediatric practice. During pregnancy, the drug can be included in therapy if there are strict indications.

Pentovit and Combilipen belong to the same pharmacological group of drugs. The drugs are prescribed to treat various neurological diseases. Pentovit is available in tablet form. Combilipen is produced in the form of tablets and solution for injection. This provides a wider range of indications.

Which is better: Combilipen or Compligam?

Compligam is a multivitamin medicine. The drug contains active ingredients cyanocobalamin, thiamine, pyridoxine and lidocaine. Compligam has a local anesthetic and analgesic effect. Produced in the form of tablets and solution for injection. Normalizes blood circulation and stimulates hematopoiesis. The main indications for prescribing the drug are:

• intercostal neuralgia;
• paresis;
• neuritis;
• convulsive syndrome;
• polyneuropathy of various origins;
• trigeminal neuralgia;
• pain syndrome due to degenerative-dystrophic diseases of the musculoskeletal system.

Compligam is not prescribed during pregnancy and lactation. The drug is not used in pediatric practice and for heart failure in the stage of decompensation.

Combilipen and Compligam belong to the same pharmacological group. A similar composition provides the same indications and contraindications for use, as well as side effects. Both drugs are produced by a domestic manufacturer.

Which is better: Combilipen or Neurobion?

Neurobion is a multivitamin medicine. The active ingredients of the drug are thiamine hydrochloride, pyridoxine hydrochloride and cyanocobalamin. Produced in the form of tablets and solution for injection. Neurobion is prescribed for the presence of various neurological diseases. The drug replenishes vitamin deficiencies, has a positive effect on the condition of nerve endings and improves impulse conduction. The main indications for prescribing Neurobion include:

• radicular syndrome;
• Bell's palsy;
• neuralgia of various origins;
• degenerative-dystrophic diseases of the musculoskeletal system.

There is no data on the negative effects of the drug on the fetus during pregnancy. However, doctors recommend using the drug only if there are strict indications and under the supervision of a specialist.

Combilipen and Neurobion are representatives of the same pharmacological group. Both drugs contain B vitamins, are prescribed for the treatment of neurological diseases, and are available in the form of tablets and injection solution. Before using medications, it is recommended to consult a doctor. The specialist will be able to assess the severity of the condition, select the most effective dosage, frequency of administration and duration of treatment. Self-medication can lead to various consequences.

Which is better: Combilipen or Movalis?

Movalis is a representative of the group of nonspecific anti-inflammatory drugs. The active substance is meloxicam. Available in the form of tablets, solution for injection, rectal suppositories and suspension. It has analgesic, anti-inflammatory and antipyretic effects. The main indications for the use of Movalis are degenerative-dystrophic diseases of the musculoskeletal system. The drug is part of the treatment of diseases such as:

• osteochondrosis;
• arthrosis;
• arthritis;
• chronic pain syndrome

The drug is not recommended for use during pregnancy and lactation.

Combilipen and Movalis are prescribed for the treatment of neurological diseases. The differences between the drugs are as follows:

• Combilipen is a complex drug whose active substances are B vitamins. Movalis is a nonspecific anti-inflammatory drug;
• The active ingredients of Combilipen are cyanocobalamin, thiamine and pyridoxine. The active substance of Movalis is considered meloxicam;
• Combilipen is available in the form of tablets and solution for injection. Movalis is produced in the form of a solution for injection, rectal suppositories, tablets and suspension for oral administration. The variety of shapes provides a wider range of uses.

Doctors often practice co-prescribing Kombilipen and Movalis. Such complex therapy allows you to shorten the treatment period.

Which is better: Combilipen or Mydocalm?

Mydocalm is a muscle relaxant drug. The active ingredient of the drug is tolperisone. Mydocalm is available in the form of tablets and solution for injection. It has a membrane-stabilizing and local anesthetic effect. Indications for the appointment of Mydocalm are:

• spasms of striated muscles;
• diseases of the central nervous system of various origins;
• muscle contractures and spasms;
• degenerative-dystrophic diseases of the musculoskeletal system;
• rehabilitation period after surgery;
• combination therapy for obliterating vascular diseases;
• disruption of vascular innervation.

Mydocalm is not used in cases of hypersensitivity to its components, with myasthenia gravis, during pregnancy and lactation, as well as in children under 3 years of age.

Combilipen and Mydocalm belong to different pharmacological groups of drugs. The active substance of Mydocalm is tolperisone. Combilipen contains active ingredients: thiamine, pyridoxine, cyanocobalamin. The drugs are available in the form of tablets and solution for injection. If there are certain indications, they can be used together as part of complex therapy for various neurological diseases.

Which is better: Combilipen or Cocarnit?

Cocarnit is a complex drug. The drug contains cyanocobalamin, cocarboxylase, nicotinamide and adenosine triphosphate. Available in the form of a lyophilisate for preparing a solution. Cocarnit has a neurometabolic and analgesic effect, and has a positive effect on the emotional background. The main indications for prescribing the drug are:

• neuritis;
• neuralgia of various origins;
• sciatica;
• bursitis;
• tendinitis;
• myalgia;
• radiculitis;
• neuropathy.

Cocarnit is used as part of complex therapy for coronary heart disease and myocarditis. Can be prescribed during pregnancy if there are strict indications and under the supervision of a doctor.

Combilipen and Cocarnit belong to the same pharmacological group. Prescribed for the treatment of neurological diseases. The drugs differ in composition. The active substances of Cocarnit are nicotinamide, cocarboxylase, cyanocobalamin and adenosine triphosphate. Combilipen contains pyridoxine, thiamine and cyanocobalamin. Cocarnit is produced in the form of a lyophilisate for the preparation of a solution. The release forms of Combilipen are tablets and solution for injection. Combilipen is not prescribed during pregnancy and lactation. Cocarnit has no such restrictions. Before using medications, it is recommended to consult a doctor. The specialist will be able to assess the severity of the condition, prescribe the necessary dosage, frequency of administration and duration of treatment.

Which is better: Combilipen or Vitaxon?

Vitaxon is a neurotropic drug. The active ingredients of the drug are thiamine, pyridoxine and cyanocobalamin. Produced in the form of tablets and solution for injection. Prescribed as part of complex therapy for various neurological diseases. The main indications for prescribing Vitaxon include:

• myalgia;
• neuralgia;
• radicular syndrome;
• polyneuropathy of various origins;
• neuritis;
• withdrawal syndrome.

The drug is not used during pregnancy and lactation, as well as in childhood, in the presence of chronic heart failure in the decompensation stage.

Kombilipen and Vitaxon are representatives of complex preparations containing B vitamins. Both drugs are produced in the form of tablets and injection solution. The similar composition of the drugs explains the same indications and contraindications for use, as well as side effects. Vitaxon is a Ukrainian-made medicine. Combilipen is produced by a domestic pharmaceutical company.

Reviews

Reviews for Combilipen are mostly positive. Patients note its beneficial effects in the complex treatment of various neurological diseases. Leaving reviews of injections and reviews on Combilipen Tabs, people note its affordable price.

Due to the presence of lidocaine in the composition, the injections are less painful than the injection of analogues containing B vitamins. Reviews of doctors about the tablets and solution of this drug indicate that it has a pronounced positive effect in the treatment of osteochondrosis . As adverse reactions, reviews mention the appearance of slight itching of the skin and urticaria.

How much does Combilipen cost?

A multivitamin complex can be purchased at a pharmacy. It is released only with a medical prescription. The injection solution costs an average of 230 rubles. The drug in tablet form is sold for 250 rubles.

In conclusion, it is worth noting that multivitamins are an excellent remedy that is effective for various diseases of the central nervous system. The medicine copes with diseases in mild and more complex forms. The constituent components are B vitamins, which provide undeniable benefits to the human body.

Price, where to buy

The average price for Combilipen in ampoules is about 350 rubles. (ampoules 2 ml, 10 pcs/). Price for ampoules in a package of 5 pcs. averages 150 rubles. In some pharmacy chains the price of Combilipen injections may be lower.

The medicine in tablet form is sold for an average of 300 rubles. (price of Combilipen Tabs tablets, 30 pieces per package). The drug in tablets (pack of 60 pieces) can be purchased at a price of 450 rubles.

• Online pharmacies in RussiaRussia
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Combilipen tabs tab.
  p.o n30Pharmstandard-Ufavita Ufimsky vitamin plant OJSC 252 rub.order
• Combilipen tabs tab. p.o n60Pharmstandard-Ufavita Ufimsky vitamin plant OJSC

  424 RUR order

Pharmacy Dialogue

• Combilipen (amp. 2 ml No. 10) FS-UfaVita

  606 rub. order

• Combilipen Tabs (tab. No. 60) FS-UfaVita

  450 rub. order

• Combilipen Tabs (tab. No. 30) FS-UfaVita

  RUB 265 order

• Combilipen (amp. 2 ml No. 5) FS-UfaVita

  155 rub. order

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